Cilacar TC 12.5 Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Swelling of face, lips, tongue, or throat
- Difficulty breathing or swallowing
- Severe dizziness or fainting
- Chest pain or irregular heartbeat
- Decreased urine output or swelling in legs
- Yellowing of skin or eyes
- Severe abdominal pain or vomiting blood
If experiencing severe symptoms, call emergency services immediately.
What is davaindia telmisartan+cilnidipine+chlorthalidone 40mg/10mg/12.5mg tablet used for?
This medicine is a combination of Telmisartan and Cilnidipine used to treat high blood pressure. It works by relaxing blood vessels and reducing peripheral resistance, thereby lowering blood pressure. It is taken once daily orally.
- Generic Name: Telmisartan + Cilnidipine
- Manufacturer: Davaindia Generic Pharmacy
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 davaindia telmisartan+cilnidipine+chlorthalidone 40mg/10mg/12.5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा उच्च रक्तचाप (हाइपरटेंशन) के इलाज के लिए इस्तेमाल की जाती है। इसमें टेल्मिसार्टन और सिल्निडिपिन दो सक्रिय तत्व होते हैं जो रक्त वाहिकाओं को आराम देकर रक्तचाप को कम करते हैं। यह उन रोगियों के लिए फायदेमंद है जिनका रक्तचाप अकेले एक दवा से नियंत्रित नहीं होता। यह गुर्दे की सुरक्षा में भी मदद कर सकती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में सिरदर्द, चक्कर आना, थकान, और पैरों में सूजन शामिल हैं। ये आमतौर पर हल्के होते हैं और कुछ समय में ठीक हो जाते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर निम्न रक्तचाप, एंजियोएडेमा (चेहरे, होंठ, गले में सूजन), और गुर्दे की समस्या शामिल हो सकती है। यदि आपको सांस लेने में कठिनाई या गंभीर चक्कर आए तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ या बिना भोजन के लिया जा सकता है, लेकिन भोजन के साथ लेने से पेट की परेशानी कम हो सकती है। शराब का सेवन न करें क्योंकि इससे चक्कर आ सकते हैं। गर्भावस्था के दौरान इस दवा का सेवन न करें। अपने डॉक्टर को अन्य सभी दवाओं के बारे में बताएं। पोटेशियम सप्लीमेंट या नमक के विकल्प बिना डॉक्टर की सलाह के न लें। नियमित रूप से रक्तचाप और गुर्दे की जांच कराएं।
💊 davaindia telmisartan+cilnidipine+chlorthalidone 40mg/10mg/12.5mg tablet Uses & Benefits
- [{"condition":"Essential Hypertension","description":"This medicine is used to lower high blood pressure in adults when monotherapy is insufficient.
- It combines two complementary mechanisms to achieve better blood pressure control.","evidence":"Well-established"},{"condition":"Hypertension with Chronic Kidney Disease","description":"The telmisartan component provides renoprotective effects, while cilnidipine may offer additional renal benefits by dilating both afferent and efferent arterioles.","evidence":"Moderate"},{"condition":"Hypertension with Angina","description":"Cilnidipine, as a calcium channel blocker, may help in reducing angina episodes by improving coronary blood flow.","evidence":"Limited"}]
Off-label uses: [{"condition":"Diabetic Nephropathy","description":"Sometimes prescribed off-label to slow the progression of kidney disease in diabetic patients due to the renoprotective effects of telmisartan.","evidence":"Moderate"},{"condition":"Heart Failure with Preserved Ejection Fraction","description":"May be used off-label in some patients with heart failure, but evidence is limited.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Chronic kidney disease, Angina, Heart failure
📋 Drug Information
| Generic Name(s) | Telmisartan + Cilnidipine |
| Brand Name | Cilacar TC 12.5 |
| Manufacturer | Davaindia Generic Pharmacy |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Angiotensin II Receptor Blocker + Calcium Channel Blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antihypertensive agents with complementary mechanisms. Telmisartan is an angiotensin II receptor blocker (ARB) that selectively blocks the AT1 receptor subtype, preventing the vasoconstrictor and aldosterone-secreting effects of angiotensin II. This leads to relaxation of blood vessels and reduced blood pressure. Cilnidipine is a dual L-type and N-type calcium channel blocker. It inhibits the influx of calcium ions into vascular smooth muscle cells, causing vasodilation. The N-type calcium channel blockade additionally inhibits sympathetic neurotransmitter release, which may contribute to its blood pressure-lowering effect and potentially offer organ protection. Together, these agents reduce peripheral vascular resistance and lower blood pressure effectively.
Mechanism Steps
💡 How to Take davaindia telmisartan+cilnidipine+chlorthalidone 40mg/10mg/12.5mg tablet
Strength: Tablet containing Telmisartan 40 mg and Cilnidipine 10 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Telmisartan 40 mg + Cilnidipine 10 mg) once daily, preferably at the same time each day. Your doctor may adjust the dose based on your blood pressure response and tolerability. The maximum recommended dose is one tablet daily. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects. Start with a lower dose and monitor closely. Dose must be individualized by a qualified clinician. |
| Renal Impairment | No dose adjustment is required for mild to moderate renal impairment. In severe renal impairment or hemodialysis patients, use with caution and monitor potassium and creatinine levels. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | Use with caution in patients with mild to moderate hepatic impairment. Contraindicated in severe hepatic impairment. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | One tablet daily (Telmisartan 40 mg + Cilnidipine 10 mg). |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of davaindia telmisartan+cilnidipine+chlorthalidone 40mg/10mg/12.5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Spironolactone | Major | |
| Lisinopril | Major | |
| Lithium | Major | |
| Ibuprofen | Moderate | |
| Ketoconazole | Moderate | |
| Rifampicin | Moderate | |
| Metoprolol | Moderate | |
| Grapefruit juice | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Potassium-sparing diuretics (e.g., spironolactone)
- ACE inhibitors (e.g., lisinopril)
- Lithium
- NSAIDs (e.g., ibuprofen)
⚡ Moderate Interactions
- CYP3A4 inhibitors (e.g., ketoconazole)
- CYP3A4 inducers (e.g., rifampicin)
- Beta-blockers
🍷 Alcohol Interaction
Alcohol may enhance the blood pressure-lowering effect of this medicine, leading to dizziness, lightheadedness, and increased risk of fainting. It is advisable to avoid or limit alcohol consumption while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to telmisartan, cilnidipine, or any component of the formulation","Pregnancy (second and third trimesters)","Severe hepatic impairment","Bilateral renal artery stenosis","Concomitant use with aliskiren in patients with diabetes"]
⚠️ Warnings & Precautions
["Avoid use in pregnancy; use effective contraception.","Monitor for hypotension, especially after first dose or in volume-depleted patients.","Monitor potassium levels, especially in patients with renal impairment or on potassium supplements.","Use with caution in patients with aortic or mitral stenosis.","May impair ability to drive or operate machinery; avoid until you know how it affects you.","Do not use potassium supplements or salt substitutes without medical advice.","Inform your doctor if you have a history of angioedema."]
🤱 Lactation Safety
It is not known whether telmisartan or cilnidipine are excreted in human breast milk. Because of the potential for adverse effects in nursing infants, a decision should be made whether to discontinue nursing or discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
Overdose may cause severe hypotension, dizziness, and tachycardia. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic. Gastric lavage may be considered if ingestion is recent. Monitor vital signs and electrolytes. There is no specific antidote.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not change the dose or stop taking it without consulting your healthcare provider. This medicine can be taken with or without food, but taking it with food may reduce the risk of stomach upset. Avoid consuming alcohol while on this medication, as it can enhance the blood pressure-lowering effect and cause dizziness. Stand up slowly from a sitting or lying position to prevent dizziness due to low blood pressure. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine is not safe during pregnancy, especially in the second and third trimesters, as it can harm the unborn baby. Use effective contraception while taking this medicine. Inform your doctor about all other medications you are taking, including over-the-counter drugs, herbal supplements, and vitamins, as interactions may occur. Do not take potassium supplements or salt substitutes containing potassium without your doctor's approval. Keep all appointments for blood pressure monitoring and lab tests. Store this medicine at room temperature, away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects and are at higher risk of dizziness and falls. Start with a lower dose and monitor closely. Regular monitoring of kidney function and electrolytes is advised.
🤰 Pregnancy Planning (TTC)
This medicine is contraindicated during pregnancy. If you are planning to become pregnant, consult your doctor to switch to a safer alternative before conception. Use effective contraception while taking this medicine.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may need to be temporarily stopped before surgery to avoid excessive hypotension during the procedure. Follow your doctor's instructions.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine, as it may affect blood pressure during dental procedures. Local anesthetics with epinephrine should be used with caution.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Regular exercise is beneficial, but avoid sudden strenuous activities if you are not used to them. Stay hydrated, and if you experience dizziness or shortness of breath, stop and rest. Consult your doctor before starting a new exercise regimen.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, especially when you first start taking it. Avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities once adjusted to the medication.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your blood pressure is well-controlled for a long period, your doctor may consider reducing the dose or switching to another medication. Abrupt discontinuation can lead to rebound hypertension.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe and effective for managing hypertension. Regular monitoring of blood pressure, kidney function, and electrolytes is recommended. Some patients may develop tolerance, requiring dose adjustment. Prolonged use may rarely cause liver enzyme elevations. Adherence to lifestyle modifications can reduce the need for higher doses.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, and stress reduction can help lower blood pressure and may reduce the need for medication.
Evidence: Well-establishedDepending on your condition, your doctor may prescribe different combinations such as ARB + diuretic or CCB + beta-blocker.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, maintain routine vaccinations as recommended by your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, consult your doctor about adjusting the dosing schedule. Carry enough supply for the entire trip plus extra in case of delays. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within a few hours, but the full effect may take 4-8 weeks. Continue taking it regularly as prescribed.
A: Yes, you can take it with or without food. Taking it with food may reduce stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: No, this medicine is not safe during pregnancy, especially in the second and third trimesters. Consult your doctor for alternative treatment if you are pregnant or planning to become pregnant.
A: No, do not stop taking this medicine without consulting your doctor. High blood pressure often has no symptoms, and stopping suddenly can cause a rebound increase.
🤔 Common Patient Concerns
🔄 Substitutes for davaindia telmisartan+cilnidipine+chlorthalidone 40mg/10mg/12.5mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia cilnidipine+telmisartan 10mg/40mg tabletDavaindia Generic Pharmacy ₹30.00 14.3% CHEAPER
-
acmetel-ln tabletAcmedix Pharma LLP ₹37.00 5.7% COSTLIER
-
cldn tm 10mg/40mg tabletDR Best pharmaceuticals Pvt Ltd ₹45.00 28.6% COSTLIER
-
telmizem c 10mg/40mg tabletZeelab Pharmacy Pvt Ltd ₹45.00 28.6% COSTLIER
-
cilogard t tabletCipla Ltd ₹45.94 31.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure high blood pressure permanently.
Fact: This medicine controls blood pressure but does not cure hypertension. Lifestyle changes and ongoing medication are usually needed. - Myth: You can stop taking this medicine once your blood pressure is normal.
Fact: Stopping suddenly can cause a rebound increase in blood pressure. Always consult your doctor before stopping. - Myth: This medicine causes kidney damage.
Fact: When used appropriately, this medicine can actually protect the kidneys, especially in patients with diabetes or kidney disease.
🔄 Alternative Options
Generic Alternatives
- Telmisartan 40 mg + Cilnidipine 10 mg tablet (generic)
Brand Alternatives
- Cilacar TC 12.5 Tablet