Cilaspene 500mg/500mg Injection
What is cilaspene 500mg/500mg injection used for?
Cilaspene 500mg/500mg Injection is an antibiotic used to treat serious bacterial infections such as intra-abdominal, urinary tract, skin, and respiratory infections. It contains imipenem, which kills bacteria, and cilastatin, which prevents its breakdown in the kidneys.
- Generic Name: Imipenem (500mg) + Cilastatin (500mg)
- Manufacturer: Sanjivani Parenteral Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
๐ cilaspene 500mg/500mg injection Uses & Benefits
Detailed medical information is being added to our database.
๐ Drug Information
| Generic Name(s) | Imipenem (500mg) + Cilastatin (500mg) |
| Brand Name | cilaspene 500mg/500mg injection |
| Manufacturer | Sanjivani Parenteral Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Information pending |
| Route of Administration | Oral |
| Storage | Room temperature (15-30ยฐC), away from moisture |
| Shelf Life | As per manufacturer |
๐ก How to Take cilaspene 500mg/500mg injection
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of cilaspene 500mg/500mg injection
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Injection site pain or redness
- Headache
๐จ Serious Side Effects
- Severe allergic reaction (rash, itching, swelling, trouble breathing)
- Seizures
- Severe diarrhea (Clostridium difficile infection)
- Blood in urine or decreased urination
โ ๏ธ Rare Side Effects
- Low white blood cell count (neutropenia)
- Liver enzyme elevation
- Pseudomembranous colitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Valproic Acid | Major | Decreased valproic acid levels, risk of seizures |
| Ganciclovir | Major | Increased risk of seizures |
| Probenecid | Moderate | Increased imipenem levels |
| Warfarin | Moderate | Increased INR |
| Theophylline | Minor | Possible increased theophylline levels |
๐จ Major Interactions
- Valproic Acid
- Ganciclovir
- Methotrexate
โก Moderate Interactions
- Warfarin
- Probenecid
- Cyclosporine
โน๏ธ Minor Interactions
- Theophylline
- Furosemide
- Heparin
๐ฝ๏ธ Food Interactions
No significant food interactions. However, it is given intravenously, so food does not affect absorption.
๐ท Alcohol Interaction
Avoid alcohol while taking this medicine as it may increase the risk of side effects like nausea and dizziness.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Do not use in patients with a history of severe allergic reaction to imipenem, cilastatin, or other beta-lactam antibiotics (e.g., penicillins, cephalosporins). Also contraindicated in patients with severe renal impairment not on dialysis.
โ ๏ธ Warnings & Precautions
Use with caution in patients with kidney disease, as dose adjustment may be needed. Monitor for signs of allergic reactions, seizures, and severe diarrhea. Prolonged use may lead to superinfections. Avoid use in patients with known hypersensitivity to imipenem or other beta-lactam antibiotics.
๐ Overdose Management
In case of overdose, seek emergency medical attention. Symptoms may include seizures, confusion, and kidney failure. Treatment is supportive and may include dialysis to remove the drug.
โฐ Missed Dose
If you miss a dose, take it as soon as possible. However, if it is almost time for the next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.