chymogo-a tablet - Aceclofenac (100mg) + Trypsin Chymotrypsin (50000IU) medicine

chymogo-a tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Accilex Nutricorp ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is chymogo-a tablet used for?

Alonac Forte (Aceclofenac + Trypsin Chymotrypsin) is used to treat PAIN ANALGESICS. It contains Aceclofenac (100mg) + Trypsin Chymotrypsin (50000IU), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Trypsin . Always consult your doctor before use. Take as prescribed.

  • Generic Name: Aceclofenac + Trypsin Chymotrypsin
  • Manufacturer: Accilex Nutricorp
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š chymogo-a tablet Uses & Benefits

Pain and inflammation in musculoskeletal disorders, post-operative inflammation

Off-label uses: Dental pain, dysmenorrhea

๐Ÿ“‹ Drug Information

Generic Name(s)Aceclofenac + Trypsin Chymotrypsin
Brand NameAlonac Forte
ManufacturerAccilex Nutricorp
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Proteolytic Enzyme
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in tissues
Protein BindingAceclofenac: >99%
MetabolismAceclofenac: Hepatic via CYP2C9; Trypsin Chymotrypsin: Proteolytic degradation
Half-LifeAceclofenac: ~4 hours; Trypsin Chymotrypsin: Not well defined
ExcretionAceclofenac: Renal (primarily as metabolites); Trypsin Chymotrypsin: Fecal
BioavailabilityAceclofenac: ~100%
Onset of ActionAceclofenac: 30-60 minutes
Peak Plasma TimeAceclofenac: 1-3 hours
Duration of ActionAceclofenac: 12-24 hours

How It Works

Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Trypsin Chymotrypsin reduces inflammation by breaking down proteins involved in inflammatory response

Mechanism Steps

1Aceclofenac inhibits cyclooxygenase (COX-1 and COX-2) enzymes
2Reduces conversion of arachidonic acid to prostaglandins
3Decreases pain and inflammation

๐Ÿ’ก How to Take chymogo-a tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of chymogo-a tablet

โœ… Common Side Effects

  • Nausea
  • Dyspepsia
  • Diarrhea
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • GI bleeding
  • Peptic ulcer
  • Renal failure
  • Hepatotoxicity
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Stevens-Johnson syndrome
  • Agranulocytosis
  • Pancreatitis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Lithium Major Increased lithium toxicity
Methotrexate Major Increased methotrexate toxicity
Aspirin Major Increased GI ulceration risk
Other NSAIDs Major Additive GI toxicity
ACE inhibitors Moderate Reduced antihypertensive effect
Diuretics Moderate Reduced diuretic effect
Anticoagulants Moderate Increased bleeding risk
Corticosteroids Moderate Increased GI ulceration risk
Antacids Minor Reduced absorption of aceclofenac
Digoxin Minor Increased digoxin levels
Cyclosporine Minor Increased nephrotoxicity risk

๐Ÿšจ Major Interactions

  • Warfarin
  • Lithium
  • Methotrexate
  • Aspirin
  • Other NSAIDs

โšก Moderate Interactions

  • ACE inhibitors
  • Diuretics
  • Anticoagulants
  • Corticosteroids

โ„น๏ธ Minor Interactions

  • Antacids
  • Digoxin
  • Cyclosporine

๐Ÿฝ๏ธ Food Interactions

May be taken with food to reduce GI upset

๐Ÿท Alcohol Interaction

Increased risk of GI bleeding

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, active peptic ulcer, severe renal/hepatic impairment, third trimester pregnancy, history of asthma with NSAIDs

๐Ÿ“Š Monitoring Parameters

Renal function, hepatic function, GI symptoms, blood pressure

๐Ÿคฑ Lactation Safety

Not recommended; excreted in breast milk

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage if recent; monitor renal function

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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