chyflam plus 50mg tablet - Uses, Price, Side Effects & Substitutes
What is chyflam plus 50mg tablet used for?
Chymoral Plus (Diclofenac + Trypsin Chymotrypsin) is used to treat PAIN ANALGESICS. It contains Diclofenac (50mg) + Trypsin Chymotrypsin (50000AU), which Diclofenac inhibits cyclooxygenase (COX-1 and COX-2), reducing prostaglandin syn. Always consult your doctor before use. Take as prescribed.
- Generic Name: Diclofenac + Trypsin Chymotrypsin
- Manufacturer: Moon Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ chyflam plus 50mg tablet Uses & Benefits
Pain and inflammation associated with trauma, surgery, dental procedures, musculoskeletal disorders.
Off-label uses: Not well documented.
๐ Drug Information
| Generic Name(s) | Diclofenac + Trypsin Chymotrypsin |
| Brand Name | Chymoral Plus |
| Manufacturer | Moon Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Nonsteroidal Anti-inflammatory Drug (NSAID) + Proteolytic Enzymes |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Diclofenac inhibits cyclooxygenase (COX-1 and COX-2), reducing prostaglandin synthesis; Trypsin Chymotrypsin hydrolyzes proteins involved in inflammation and edema.
Mechanism Steps
๐ก How to Take chyflam plus 50mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of chyflam plus 50mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Dyspepsia
- Abdominal pain
- Headache
- Dizziness
- Rash
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Renal failure
- Hepatotoxicity
- Anaphylaxis
- Stevens-Johnson syndrome
- Cardiovascular thrombotic events
โ ๏ธ Rare Side Effects
- Pancreatitis
- Aseptic meningitis
- Hematologic disorders
- Interstitial nephritis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Lithium | Major | Increased lithium toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| Aspirin | Major | Increased GI ulceration risk |
| Other NSAIDs | Major | Additive GI and renal toxicity |
| Anticoagulants | Major | Increased bleeding risk |
| Corticosteroids | Major | Increased GI ulceration risk |
| ACE inhibitors | Moderate | Reduced antihypertensive effect |
| Diuretics | Moderate | Reduced diuretic effect, increased nephrotoxicity |
| Cyclosporine | Moderate | Increased nephrotoxicity |
| Tacrolimus | Moderate | Increased nephrotoxicity |
| Quinolone antibiotics | Moderate | Increased risk of seizures |
| Antacids | Minor | Reduced absorption of Diclofenac |
| Digoxin | Minor | Increased digoxin levels |
| Phenytoin | Minor | Increased phenytoin levels |
๐จ Major Interactions
- Warfarin
- Lithium
- Methotrexate
- Aspirin
- Other NSAIDs
- Anticoagulants
- Corticosteroids
โก Moderate Interactions
- ACE inhibitors
- Diuretics
- Cyclosporine
- Tacrolimus
- Quinolone antibiotics
โน๏ธ Minor Interactions
- Antacids
- Digoxin
- Phenytoin
๐ฝ๏ธ Food Interactions
Food may delay absorption of Diclofenac; avoid high-fat meals.
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active GI bleeding, severe renal/hepatic impairment, history of asthma with NSAIDs, third trimester pregnancy.
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of GI bleeding.
๐คฑ Lactation Safety
Excreted in breast milk; avoid or use with caution.
๐ Overdose Management
Symptomatic and supportive; gastric lavage, activated charcoal; monitor for GI bleeding, renal failure.
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double dose.