chemitol injection - Glycerin (10gm) + Mannitol (10gm) medicine

chemitol injection

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🏭 Lee Chem Biotech Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026

What is chemitol injection used for?

This medicine contains Glycerin (10gm) + Mannitol (10gm) and is used to treat BLOOD RELATED. Increases plasma osmolality, drawing water from tissues into the bloodstream, thereby reducing intra. Always consult your doctor before use.

  • Generic Name: Glycerin + Mannitol
  • Manufacturer: Lee Chem Biotech Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category C
  • Prescription Required: Yes
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💊 chemitol injection Uses & Benefits

Reduction of intracranial pressure, reduction of intraocular pressure, promotion of diuresis in acute renal failure

Off-label uses: Treatment of acute glaucoma, cerebral edema in traumatic brain injury

📋 Drug Information

Generic Name(s)Glycerin + Mannitol
Brand NameChemitol Injection
ManufacturerLee Chem Biotech Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassBLOOD RELATED
Action ClassOsmotic diuretic
Route of AdministrationIntravenous
StorageStore at 20-25°C; protect from freezing
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionNot applicable (intravenous administration)
DistributionDistributes primarily in extracellular fluid; does not cross blood-brain barrier significantly
Protein BindingNegligible
MetabolismMinimal; primarily excreted unchanged
Half-Life0.5-1 hour (Mannitol); 2-4 hours (Glycerin)
ExcretionRenal (unchanged)
Bioavailability100% (intravenous)
Onset of ActionWithin 15-30 minutes
Peak Plasma Time30-60 minutes
Duration of Action4-6 hours

How It Works

Increases plasma osmolality, drawing water from tissues into the bloodstream, thereby reducing intracranial and intraocular pressure.

Mechanism Steps

1Intravenous administration increases plasma osmolality.
2Creates an osmotic gradient between blood and tissues.
3Water moves from tissues (e.g., brain, eye) into the bloodstream.
4Reduces tissue edema and intracranial/intraocular pressure.
5Increases renal blood flow and glomerular filtration rate.
6Osmotic diuresis occurs as mannitol and glycerin are filtered but not reabsorbed.
7Excretion of water and electrolytes in urine.

💡 How to Take chemitol injection

Follow your doctor's prescription exactly.

⚠️ Side Effects of chemitol injection

✅ Common Side Effects

Headache
Nausea
Vomiting
Electrolyte imbalance
Dehydration

🚨 Serious Side Effects

Acute renal failure
Pulmonary edema
Intracranial hemorrhage
Seizures

⚠️ Rare Side Effects

Allergic reactions
Thrombophlebitis
Hyperosmolar coma

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Lithium Major Increased risk of lithium toxicity due to decreased renal clearance
Cyclosporine Major Increased risk of nephrotoxicity
Aminoglycosides Major Increased risk of nephrotoxicity and ototoxicity
Diuretics Moderate Additive diuretic effect, risk of electrolyte imbalance
ACE inhibitors Moderate Increased risk of hypotension and hyperkalemia
NSAIDs Moderate Reduced diuretic effect, increased risk of nephrotoxicity
Corticosteroids Minor Increased risk of hyperglycemia
Digoxin Minor Increased risk of digoxin toxicity due to electrolyte disturbances

🚨 Major Interactions

  • Lithium
  • Cyclosporine
  • Aminoglycosides

⚡ Moderate Interactions

  • Diuretics
  • ACE inhibitors
  • NSAIDs

🍷 Alcohol Interaction

May increase risk of dehydration and electrolyte imbalance

🛡️ Safety & Warnings

🚫 Contraindications

Anuria, severe dehydration, intracranial hemorrhage, severe pulmonary edema, hypersensitivity to any component

🤱 Lactation Safety

Use with caution; not known if excreted in breast milk

💊 Overdose Management

Discontinue infusion; monitor electrolytes and renal function; supportive care including fluid and electrolyte replacement

⏰ Missed Dose

Administer as soon as remembered; do not double dose

🔄 Substitutes for chemitol injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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