cetalic 250mg injection - Ceftazidime (250mg) medicine

cetalic 250mg injection - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Anabolic Remedies Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is cetalic 250mg injection used for?

Akuzid 1000 Injection (Ceftazidime) is used to treat ANTI INFECTIVES. It contains Ceftazidime (250mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ceftazidime
  • Manufacturer: Anabolic Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š cetalic 250mg injection Uses & Benefits

Treatment of infections caused by susceptible organisms including lower respiratory tract, skin and skin structure, urinary tract, intra-abdominal, gynecologic, septicemia, and meningitis.

Off-label uses: Febrile neutropenia, Melioidosis, Burkholderia cepacia infections

๐Ÿ“‹ Drug Information

Generic Name(s)Ceftazidime
Brand NameAkuzid 1000 Injection
ManufacturerAnabolic Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 3 generation
Route of AdministrationIntravenous (IV) or intramuscular (IM).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light; reconstituted solutions stable for 24 hours at room temperature or 7 days refrigerated.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular administration results in rapid and complete absorption; intravenous administration provides immediate bioavailability.
DistributionWidely distributed into body tissues and fluids including pleural, peritoneal, synovial, and cerebrospinal fluid (when meninges inflamed).
Protein BindingApproximately 10-17% bound to plasma proteins.
MetabolismNot significantly metabolized; primarily excreted unchanged.
Half-Life1.5-2 hours in patients with normal renal function.
ExcretionRenal excretion via glomerular filtration; >80% excreted unchanged in urine within 24 hours.
Bioavailability100% (IV); ~90% (IM).
Onset of ActionRapid (within 1 hour for IM).
Peak Plasma TimeIM: 1-2 hours; IV: end of infusion.
Duration of ActionApproximately 8-12 hours depending on renal function.

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death.

Mechanism Steps

1Ceftazidime binds to penicillin-binding proteins (PBPs) located on the bacterial cell wall.
2Inhibition of transpeptidase enzymes prevents cross-linking of peptidoglycan chains.
3Disruption of cell wall synthesis leads to osmotic instability and bacterial cell lysis.

๐Ÿ’ก How to Take cetalic 250mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cetalic 250mg injection

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Injection site reactions

๐Ÿšจ Serious Side Effects

  • Clostridioides difficile colitis
  • Seizures
  • Anaphylaxis
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Hemolytic anemia
  • Agranulocytosis
  • Thrombocytopenia
  • Interstitial nephritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Aminoglycosides Major Increased risk of nephrotoxicity and ototoxicity
Loop diuretics Major Increased risk of nephrotoxicity
Chloramphenicol Major Antagonistic effect
Probenecid Moderate Decreased renal excretion of ceftazidime
Oral contraceptives Moderate Reduced contraceptive efficacy
Warfarin Moderate Increased INR and bleeding risk
Live bacterial vaccines Minor Reduced vaccine efficacy
BCG vaccine Minor Reduced vaccine efficacy

๐Ÿšจ Major Interactions

  • Aminoglycosides
  • Loop diuretics
  • Chloramphenicol

โšก Moderate Interactions

  • Probenecid
  • Oral contraceptives
  • Warfarin

โ„น๏ธ Minor Interactions

  • Live bacterial vaccines
  • BCG vaccine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to ceftazidime or any cephalosporin; history of severe immediate hypersensitivity reaction to penicillins or other beta-lactams.

๐Ÿ“Š Monitoring Parameters

Renal function (especially in elderly or those on nephrotoxic drugs), signs of superinfection, hypersensitivity reactions, and bleeding.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination.

โฐ Missed Dose

Administer as soon as remembered; if close to next dose, skip missed dose and resume regular schedule; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cetalic 250mg injection

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Alternative brands with exact same active ingredient (Ceftazidime (250mg)):

Medical Note: Always consult your doctor before switching medications.

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