acelic-th4 tablet - Uses, Price, Side Effects & Substitutes
What is acelic-th4 tablet used for?
Aldigesic TH 100mg/4mg Tablet (Aceclofenac + Thiocolchicoside) is used to treat PAIN ANALGESICS. It contains Aceclofenac (100mg) + Thiocolchicoside (4mg), which Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Thiocolc. Always consult your doctor before use. Take as prescribed.
- Generic Name: Aceclofenac + Thiocolchicoside
- Manufacturer: Anabolic Remedies Pvt Ltd
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ acelic-th4 tablet Uses & Benefits
Acute musculoskeletal pain, osteoarthritis, rheumatoid arthritis, ankylosing spondylitis, muscle spasms
Off-label uses: Postoperative pain, dental pain, dysmenorrhea
๐ Drug Information
| Generic Name(s) | Aceclofenac + Thiocolchicoside |
| Brand Name | Aldigesic TH 100mg/4mg Tablet |
| Manufacturer | Anabolic Remedies Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | NSAID + Muscle Relaxant |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from moisture and light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Aceclofenac inhibits COX-1 and COX-2, reducing prostaglandin synthesis; Thiocolchicoside acts as a GABA-A receptor agonist and glycine receptor agonist, producing muscle relaxation
Mechanism Steps
๐ก How to Take acelic-th4 tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of acelic-th4 tablet
โ Common Side Effects
- Nausea
- Vomiting
- Diarrhea
- Constipation
- Dizziness
- Headache
- Somnolence
- Abdominal pain
- Dyspepsia
๐จ Serious Side Effects
- GI bleeding
- Peptic ulcer
- Hepatotoxicity
- Nephrotoxicity
- Cardiovascular events
- Stevens-Johnson syndrome
- Anaphylaxis
- Bone marrow suppression
โ ๏ธ Rare Side Effects
- Pancreatitis
- Hearing loss
- Tinnitus
- Aseptic meningitis
- Photosensitivity
- Agranulocytosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Lithium | Major | Increased lithium toxicity |
| Methotrexate | Major | Increased methotrexate toxicity |
| Aspirin | Major | Increased GI ulceration risk |
| Corticosteroids | Major | Increased GI bleeding risk |
| Diuretics | Major | Reduced diuretic efficacy |
| ACE inhibitors | Major | Reduced antihypertensive effect |
| Cyclosporine | Major | Increased nephrotoxicity |
| SSRIs | Moderate | Increased bleeding risk |
| Alcohol | Moderate | Increased GI bleeding and hepatotoxicity |
๐จ Major Interactions
- Warfarin
- Lithium
- Methotrexate
- Anticoagulants
- Aspirin
- Corticosteroids
- Diuretics
- ACE inhibitors
- Cyclosporine
- Tacrolimus
โก Moderate Interactions
- SSRIs
- SNRIs
- Antiplatelet agents
- Pentoxifylline
- Zidovudine
- Pemetrexed
โน๏ธ Minor Interactions
- Beta-blockers
- Digoxin
- Phenytoin
- Sulfonylureas
๐ฝ๏ธ Food Interactions
May be taken with food to reduce GI upset; avoid alcohol
๐ท Alcohol Interaction
Increased risk of GI bleeding and hepatotoxicity
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, active peptic ulcer, bleeding disorders, severe renal/hepatic impairment, pregnancy, lactation, children <18 years, history of asthma, CVS disease
๐ Monitoring Parameters
Liver function, renal function, CBC, blood pressure, signs of GI bleeding
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Symptomatic and supportive; gastric lavage, activated charcoal; monitor for GI bleeding, renal function, CNS depression
โฐ Missed Dose
Take as soon as remembered; if near next dose, skip missed dose; do not double dose