Anbrol 50mg/500mg Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or slow, shallow breathing
- Seizures or convulsions
- Severe abdominal pain or vomiting blood
- Yellowing of the skin or eyes
- Signs of an allergic reaction: rash, itching, swelling of face, lips, or throat
- Agitation, hallucinations, fever, sweating, or muscle stiffness (serotonin syndrome)
- Inability to urinate
- Severe dizziness or fainting
If experiencing severe symptoms, call emergency services immediately.
What is cetadol 50mg/500mg tablet used for?
This medicine is a combination of tramadol (an opioid analgesic) and paracetamol (an analgesic and antipyretic) used for short-term relief of moderate to severe acute pain. It works by blocking pain signals in the brain and spinal cord. It should be taken exactly as prescribed, with food, and not for longer than recommended due to risks of dependence and liver damage.
- Generic Name: Tramadol + Paracetamol
- Manufacturer: Rut Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cetadol 50mg/500mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा ट्रामाडोल और पैरासिटामोल का संयोजन है, जिसका उपयोग मध्यम से गंभीर तीव्र दर्द के अल्पकालिक उपचार के लिए किया जाता है। यह सर्जरी, दांत निकालने, या मस्कुलोस्केलेटल चोट के बाद होने वाले दर्द में प्रभावी है। यह दवा दर्द के संकेतों को मस्तिष्क और रीढ़ की हड्डी में अवरुद्ध करके काम करती है। इसे डॉक्टर के निर्देशानुसार ही लें और लंबे समय तक उपयोग न करें, क्योंकि इससे निर्भरता और यकृत की क्षति का खतरा हो सकता है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, चक्कर आना, नींद आना, सिरदर्द, कब्ज, मुंह सूखना और पसीना आना शामिल हैं। गंभीर दुष्प्रभावों में दौरे, सांस लेने में कठिनाई, सेरोटोनिन सिंड्रोम, गंभीर एलर्जी, यकृत की क्षति और निर्भरता शामिल हो सकते हैं। यदि आपको सांस लेने में कठिनाई, दौरे, गंभीर पेट दर्द, या त्वचा या आंखों का पीला पड़ना महसूस हो, तो तुरंत चिकित्सा सहायता लें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। अनुशंसित खुराक या अवधि से अधिक न लें। इस दवा के साथ शराब और अन्य केंद्रीय तंत्रिका तंत्र अवसादकों से बचें। जब तक आपको पता न चले कि यह दवा आपको कैसे प्रभावित करती है, तब तक वाहन न चलाएं या भारी मशीनरी न चलाएं। यदि आपको यकृत या गुर्दे की बीमारी, दौरे, सांस की समस्या, या नशे की लत का इतिहास है, तो अपने डॉक्टर को बताएं। इस दवा को बच्चों और पालतू जानवरों से दूर रखें।
💊 cetadol 50mg/500mg tablet Uses & Benefits
[{"condition":"Acute moderate to severe pain","description":"This medicine is indicated for the short-term management of moderate to moderately severe acute pain, such as postoperative pain, dental pain, or musculoskeletal pain, when non-opioid analgesics are insufficient.","evidence":"Well-established"},{"condition":"Postoperative pain","description":"Used for the relief of pain following surgical procedures, often as part of a multimodal analgesia approach.","evidence":"Well-established"},{"condition":"Dental pain","description":"Effective for managing moderate to severe dental pain, including after tooth extraction or other oral surgical procedures.","evidence":"Well-established"},{"condition":"Musculoskeletal pain","description":"May be used for short-term relief of moderate to severe musculoskeletal pain, such as back pain or sprains, when other treatments are inadequate.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Neuropathic pain","description":"Sometimes prescribed off-label for neuropathic pain, though evidence is limited and other agents are generally preferred.","evidence":"Limited"},{"condition":"Chronic pain syndromes","description":"Rarely used off-label for chronic pain conditions, but long-term use is discouraged due to risks of dependence and tolerance.","evidence":"Limited"}]
Primary treatment for: Acute moderate to severe pain
Also treats: Postoperative pain, Dental pain, Musculoskeletal pain
📋 Drug Information
| Generic Name(s) | Tramadol + Paracetamol |
| Brand Name | Anadol P |
| Manufacturer | Rut Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | PAIN ANALGESICS |
| Action Class | Opioid analgesic + Non-opioid analgesic |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two analgesics with complementary mechanisms. Tramadol is a centrally acting opioid analgesic that binds to mu-opioid receptors and also inhibits the reuptake of norepinephrine and serotonin, enhancing descending inhibitory pain pathways. Paracetamol acts primarily in the central nervous system to reduce pain and fever, likely by inhibiting prostaglandin synthesis and modulating pain perception. Together, they provide synergistic pain relief.
Mechanism Steps
💡 How to Take cetadol 50mg/500mg tablet
Strength: Tablet containing Tramadol 50 mg and Paracetamol 500 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet (Tramadol 50 mg + Paracetamol 500 mg) taken orally every 4 to 6 hours as needed for pain, not to exceed 8 tablets in 24 hours. The maximum daily dose of tramadol should not exceed 400 mg and paracetamol should not exceed 4000 mg from all sources. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not use for longer than recommended without medical supervision. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 12 years of age. |
| Elderly Dosage | Elderly patients (above 65 years) may be more sensitive to the effects of tramadol and paracetamol. Start with a lower dose and monitor closely for side effects such as dizziness, sedation, and respiratory depression. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose adjustment may be necessary. For creatinine clearance less than 30 mL/min, the dosing interval should be increased to every 12 hours, and the maximum daily dose should not exceed 2 tablets. Consult a doctor for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, dose reduction is recommended. Avoid use in severe hepatic impairment. Consult a doctor for individualized dosing. |
| Maximum Daily Dose | Maximum 8 tablets in 24 hours, not to exceed 400 mg tramadol and 4000 mg paracetamol from all sources. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cetadol 50mg/500mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | |
| CNS depressants | Major | |
| Warfarin | Major | |
| Carbamazepine | Major | |
| SSRIs/SNRIs | Major | |
| CYP2D6 inhibitors | Moderate | |
| CYP3A4 inducers | Moderate | |
| CYP3A4 inhibitors | Moderate | |
| Diuretics | Moderate | |
| Anticholinergics | Moderate |
🚨 Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- CNS depressants (e.g., alcohol, benzodiazepines, opioids)
- Warfarin
- Carbamazepine
- SSRIs, SNRIs, triptans, tramadol
⚡ Moderate Interactions
- CYP2D6 inhibitors (e.g., fluoxetine, paroxetine, quinidine)
- CYP3A4 inducers (e.g., rifampin, St. John's wort)
- CYP3A4 inhibitors (e.g., ketoconazole, erythromycin)
- Diuretics
- Anticholinergics
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Concurrent use can increase the risk of liver damage, respiratory depression, sedation, and other serious side effects. It can also impair judgment and coordination.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to tramadol, paracetamol, or any component of the formulation","Severe respiratory depression or acute or severe bronchial asthma","Known or suspected gastrointestinal obstruction, including paralytic ileus","Concurrent use with MAOIs or within 14 days of MAOI therapy","Severe hepatic or renal impairment","Children under 12 years of age","Pregnancy and breastfeeding (unless advised by doctor)","History of substance abuse or dependence"]
⚠️ Warnings & Precautions
["Risk of dependence and withdrawal with prolonged use.","Risk of seizures, especially in patients with a history of seizures or those taking other seizure-threshold-lowering drugs.","Risk of serotonin syndrome when used with serotonergic drugs.","Risk of respiratory depression, especially in elderly or debilitated patients.","Risk of liver damage with high doses of paracetamol or alcohol use.","May impair mental and physical abilities required for driving or operating machinery.","Use with caution in patients with head injury, increased intracranial pressure, or central nervous system depression.","Not recommended for chronic pain unless under close medical supervision."]
🤱 Lactation Safety
Tramadol and paracetamol are excreted in breast milk. Use is not recommended during breastfeeding unless advised by a doctor, as it may cause sedation and respiratory depression in the infant.
💊 Overdose Management
Overdose of this medicine can cause severe liver damage, respiratory depression, seizures, and coma. Seek immediate medical attention. Treatment includes supportive care, activated charcoal if within 1-2 hours of ingestion, N-acetylcysteine for paracetamol toxicity, and naloxone for opioid toxicity. Hemodialysis may be considered in severe cases.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration of treatment. Avoid alcohol and other central nervous system depressants while taking this medicine, as they can increase drowsiness and the risk of respiratory depression. Do not drive or operate heavy machinery until you know how this medicine affects you. Inform your doctor if you have a history of liver or kidney disease, seizures, breathing problems, or substance abuse. Do not use this medicine for longer than recommended without medical supervision, as it can lead to dependence. Keep this medicine out of reach of children and pets. Store at room temperature away from moisture and heat. Do not share this medicine with others, even if they have similar symptoms.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more sensitive to the effects of tramadol and paracetamol. They may experience increased drowsiness, dizziness, and respiratory depression. Start with a lower dose and monitor closely. Dose adjustment is often necessary.
🤰 Pregnancy Planning (TTC)
This medicine is not recommended during pregnancy or when planning pregnancy unless clearly needed and advised by a doctor. Consult your doctor for alternative pain management options.
🏥 Post-Surgery Considerations
This medicine is often used for postoperative pain. It should be used for the shortest duration possible and under medical supervision. Monitor for side effects and follow your surgeon's instructions.
🦷 Dental Procedures
This medicine may be prescribed for dental pain after procedures. Inform your dentist if you are taking this medicine before any dental work. It may interact with anesthetics and other medications used during dental procedures.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid activities that require mental alertness or coordination, such as driving or operating machinery, until you know how it affects you. Consult your doctor before starting any exercise program, especially after surgery or injury.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine can cause drowsiness, dizziness, and impaired concentration, which may affect your ability to work, drive, or operate machinery. Avoid these activities until you know how the medicine affects you. Inform your employer if your job requires such activities.
🛑 When to Stop This Medicine
Stop taking this medicine when your pain is adequately controlled or as advised by your doctor. Do not stop abruptly after long-term use; consult your doctor for a tapering schedule to avoid withdrawal symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine can lead to tolerance, dependence, and withdrawal symptoms. It may also increase the risk of liver damage due to paracetamol and seizures due to tramadol. Regular monitoring of liver and kidney function is recommended. This medicine should not be used for chronic pain unless under close medical supervision.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can complement medicine for chronic pain and improve function.
Evidence: Well-establishedNSAIDs or paracetamol alone may be sufficient for mild to moderate pain.
Evidence: Well-establishedRelaxation, meditation, and cognitive behavioral therapy can help manage pain.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
Not established from the available information. Consult your doctor regarding vaccination timing while taking this medicine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust dosing intervals as advised by your doctor. Check local customs regulations regarding controlled substances, as tramadol may be restricted in some countries.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine usually starts relieving pain within 30 to 60 minutes after taking it orally.
A: The pain-relieving effect typically lasts for about 4 to 6 hours.
A: It is best to take this medicine with food to reduce the risk of nausea and stomach upset.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Do not stop this medicine abruptly after long-term use, as it can cause withdrawal symptoms. Consult your doctor for a tapering schedule.
🤔 Common Patient Concerns
🔄 Substitutes for cetadol 50mg/500mg tablet
View AllAlternative brands with exact same active ingredient:
-
Tramanat Plus TabletNature Biotech ₹23.44 56.1% CHEAPER
-
Tramnom-P 50mg/500mg TabletAcinom Healthcare ₹34.00 36.4% CHEAPER
-
scudol p 50mg/500mg tabletScutage Pharmaceuticals ₹35.63 33.3% CHEAPER
-
aldol tp 50mg/500mg tabletAltar Healthcare Pvt Ltd ₹37.50 29.8% CHEAPER
-
dolin plus tabletSerin Formulations Pvt Ltd ₹37.97 28.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is safe to take for any type of pain.
Fact: This medicine is only for moderate to severe acute pain and should not be used for mild pain or chronic pain without medical supervision. - Myth: It is okay to drink alcohol while taking this medicine.
Fact: Alcohol increases the risk of liver damage, respiratory depression, and other serious side effects. It should be avoided. - Myth: This medicine is not addictive.
Fact: Tramadol can cause dependence and withdrawal, especially with prolonged use. It should be used only as prescribed. - Myth: You can stop this medicine abruptly after long-term use.
Fact: Abrupt discontinuation can cause withdrawal symptoms. Consult your doctor for a tapering schedule.
🔄 Alternative Options
Generic Alternatives
- Tramadol 50 mg + Paracetamol 500 mg tablet (generic)
Brand Alternatives
- Anbrol 50mg/500mg Tablet