cerofene 100mg tablet - Clomiphene (100mg) medicine

Clofert 100 Tablet: Complete Guide to Uses, Dosage, and Safety

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🏭 Merck Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 16, 2026
⚠️ Hepatotoxicity Risk 🤰 Pregnancy Category Not recommended during pregnancy. This medicine is used to induce ovulation and should be stopped if pregnancy occurs. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for ovulation induction.
Reviewed by
SaathiMed Expert Panel | Oct 16, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Severe abdominal pain or bloating
  • Rapid weight gain or swelling
  • Difficulty breathing or chest pain
  • Blurred or double vision, or vision loss
  • Yellowing of skin or eyes
  • Severe allergic reaction with swelling of face, lips, or throat
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is cerofene 100mg tablet used for?

This medicine is an oral tablet containing Clomiphene 100 mg, used to treat certain types of female infertility by inducing ovulation. It works by blocking estrogen receptors in the brain, leading to increased release of hormones that stimulate the ovaries to release eggs.

  • Generic Name: Clomiphene
  • Manufacturer: Merck Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cerofene 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा क्लोमिफीन 100 मिलीग्राम की गोली है, जिसका उपयोग महिलाओं में ओव्यूलेशन को प्रेरित करने के लिए किया जाता है। यह उन महिलाओं के लिए है जो नियमित रूप से ओव्यूलेट नहीं करती हैं, जैसे कि पीसीओएस वाली महिलाएं। यह दवा मस्तिष्क में एस्ट्रोजन रिसेप्टर्स को ब्लॉक करके काम करती है, जिससे फॉलिकल-स्टिमुलेटिंग हार्मोन और ल्यूटिनाइजिंग हार्मोन का स्तर बढ़ता है। इन हार्मोनों के कारण अंडाशय में अंडे का विकास और रिलीज होता है। इस दवा का उपयोग पुरुषों में कम टेस्टोस्टेरोन के इलाज के लिए भी किया जा सकता है, लेकिन यह केवल विशेषज्ञ की देखरेख में ही करना चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में गर्म लालिमा, मतली, उल्टी, पेट में असुविधा, सूजन, स्तन में कोमलता, सिरदर्द और दृष्टि में बदलाव शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन ओवेरियन हाइपरस्टिमुलेशन सिंड्रोम, लीवर की समस्या, गंभीर दृष्टि परिवर्तन और एलर्जी प्रतिक्रियाएं हो सकती हैं। यदि आपको गंभीर पेट दर्द, अचानक वजन बढ़ना, सांस लेने में कठिनाई या दृष्टि में कमी हो, तो तुरंत चिकित्सा सहायता लें।

सुरक्षा सलाह: इस दवा को अपने डॉक्टर के निर्देशानुसार ही लें। अपने आप से खुराक न बढ़ाएं या घटाएं। यह दवा आमतौर पर मासिक धर्म चक्र के एक निश्चित दिन से शुरू करके कुछ दिनों तक ली जाती है। नियमित जांच, जैसे अल्ट्रासाउंड और हार्मोन टेस्ट, करवाते रहें। यदि आपको धुंधली दृष्टि या चक्कर आए तो वाहन चलाने से बचें। गर्भवती होने पर या गर्भधारण की योजना बनाते समय डॉक्टर को सूचित करें। स्तनपान के दौरान इस दवा का सेवन न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 cerofene 100mg tablet Uses & Benefits

[{"condition":"Anovulatory infertility","description":"This medicine is used to induce ovulation in women who do not ovulate regularly, such as those with polycystic ovary syndrome.","evidence":"Well-established"},{"condition":"Luteal phase defect","description":"Sometimes used to improve luteal phase function in women with infertility.","evidence":"Limited"},{"condition":"Male hypogonadism","description":"Off-label use to stimulate testosterone production in men with low testosterone.","evidence":"Limited"},{"condition":"Male infertility","description":"Off-label use to improve sperm production in some men with infertility.","evidence":"Limited"}]

Off-label uses: [{"condition":"Male hypogonadism","description":"Sometimes prescribed off-label to increase testosterone levels in men.","evidence":"Limited"},{"condition":"Male infertility","description":"May be used off-label to improve sperm count and motility.","evidence":"Limited"}]

Primary treatment for: Anovulatory infertility

Also treats: Polycystic ovary syndrome, Luteal phase defect

📋 Drug Information

Generic Name(s)Clomiphene
Brand NameAxifert 50mg Tablet
ManufacturerMerck Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassGYNAECOLOGICAL
Action ClassPartial estrogen agonist
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine at the same time each day to maintain consistent hormone levels.
2
Attend all monitoring appointments, including ultrasound scans, to track ovulation and detect any ovarian enlargement.
3
Report any visual disturbances immediately, as this may require stopping the medicine.
4
Avoid alcohol while taking this medicine to reduce the risk of dizziness and nausea.
5
Do not take this medicine if you are already pregnant; it is intended to induce ovulation, not to maintain pregnancy.
6
Inform your doctor about all other medicines you are taking, especially hormonal treatments.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Irregular menstrual cycles
This medicine is commonly prescribed for anovulatory infertility.
Likely Use
✅
Infertility
This medicine is used to induce ovulation in women with infertility.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration.
DistributionIt is widely distributed in the body, with high concentrations in the liver, kidneys, and reproductive tissues.
Protein BindingApproximately 90% bound to plasma proteins.
MetabolismIt is metabolized in the liver, primarily by the cytochrome P450 enzyme system.
Half-LifeThe elimination half-life is approximately 5 to 7 days.
ExcretionIt is mainly excreted in the feces via bile, with a small amount excreted in urine.
BioavailabilityThe oral bioavailability is approximately 90%.
Onset of ActionOvulation typically occurs 5 to 10 days after the last dose of a treatment cycle.
Peak Plasma TimePeak plasma concentrations are reached 6 to 8 hours after oral administration.
Duration of ActionThe effects on ovulation last for the duration of the treatment cycle, typically 5 days of dosing.

How It Works

This medicine works by binding to estrogen receptors in the hypothalamus and pituitary gland, blocking the normal feedback inhibition by estrogen. This leads to increased secretion of gonadotropin-releasing hormone, which in turn stimulates the release of follicle-stimulating hormone and luteinizing hormone from the pituitary. These hormones then act on the ovaries to promote follicular development and ovulation.

Mechanism Steps

1
Binding to estrogen receptors: This medicine binds to estrogen receptors in the hypothalamus and pituitary gland.
2
Blockade of estrogen feedback: By occupying the receptors, it prevents estrogen from exerting its negative feedback on gonadotropin-releasing hormone secretion.
3
Increased GnRH secretion: The hypothalamus increases its release of gonadotropin-releasing hormone.
4
Increased FSH and LH release: The pituitary gland responds by releasing more follicle-stimulating hormone and luteinizing hormone into the bloodstream.
5
Ovarian stimulation: These hormones stimulate the ovaries to develop follicles and eventually release an egg during ovulation.

💡 How to Take cerofene 100mg tablet

Strength: Tablet, 100 mg

1Take this medicine by mouth with or without food.
2Swallow the tablet whole with a glass of water.
3Take it at the same time each day to maintain consistent levels.
4Follow the specific dosing schedule provided by your doctor.
5Do not crush or chew the tablet.

Dosage Information

Adult DosageThe usual adult dose is 50 mg once daily for 5 days, starting on the 5th day of the menstrual cycle. If ovulation does not occur, the dose may be increased to 100 mg once daily for 5 days in the next cycle. The maximum recommended dose is 100 mg per day. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageSafety and efficacy in elderly patients have not been established. Use with caution.
Renal ImpairmentNo specific dose adjustment recommended. Use with caution in patients with renal impairment.
Hepatic ImpairmentContraindicated in patients with liver disease. Use with caution in mild hepatic impairment.
Maximum Daily Dose100 mg per day

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With or without food
Take as directed
Food does not significantly affect absorption.
Grapefruit
Avoid
May increase drug levels by affecting liver enzymes.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cerofene 100mg tablet

✅ Common Side Effects

Hot flushes (Common (10-20%))
Usually resolves without treatment. Consult your doctor if bothersome.
Nausea (Common (5-10%))
Take with food to reduce nausea. If persistent, consult your doctor.
Abdominal discomfort (Common (5-10%))
Usually mild and temporary. Report severe pain to your doctor.
Breast tenderness (Common (5-10%))
Wear a supportive bra. Consult if severe.
Headache (Common (5-10%))
Rest and stay hydrated. Use pain relief only if approved by your doctor.
Visual disturbances (Uncommon (1-5%))
Stop the medicine and inform your doctor immediately if you experience blurred or double vision.

🚨 Serious Side Effects

Ovarian hyperstimulation syndrome (Rare (<1%))
Seek immediate medical attention if you have severe abdominal pain, bloating, rapid weight gain, or difficulty breathing.
Liver toxicity (Rare (<1%))
Report yellowing of skin or eyes, dark urine, or severe fatigue to your doctor immediately.
Severe visual changes (Rare (<1%))
Stop the medicine and seek immediate medical attention if you experience vision loss or persistent visual disturbances.
Allergic reactions (Rare (<1%))
Seek emergency care if you develop rash, itching, swelling of face or throat, or difficulty breathing.

⚠️ Rare Side Effects

Ovarian cysts
Report pelvic pain or bloating to your doctor.
Thromboembolic events
Seek immediate care for leg pain, swelling, chest pain, or shortness of breath.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Hormonal contraceptives Major
Tamoxifen Major
Cimetidine Moderate
Antidiabetic drugs Moderate

🚨 Major Interactions

  • Hormonal contraceptives
  • Tamoxifen

⚡ Moderate Interactions

  • Cimetidine
  • Antidiabetic drugs

🍷 Alcohol Interaction

Alcohol may worsen side effects such as dizziness, nausea, and headache. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Pregnancy","Liver disease","Abnormal uterine bleeding of unknown cause","Ovarian cysts (except those due to polycystic ovary syndrome)","Hormone-sensitive cancers","Hypersensitivity to clomiphene"]

⚠️ Warnings & Precautions

["Use only under specialist supervision.","May cause visual disturbances; avoid driving if affected.","Risk of multiple pregnancies (twins, triplets).","May cause ovarian hyperstimulation syndrome.","Not for use in children.","Use with caution in patients with thyroid or adrenal disorders."]

🤱 Lactation Safety

Not recommended during breastfeeding. It is not known if this medicine passes into breast milk, and it may affect milk production.

💊 Overdose Management

Overdose may cause nausea, vomiting, hot flushes, visual disturbances, and ovarian hyperstimulation. Seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without consulting your doctor. This medicine is usually taken for a specific number of days in each cycle, starting on a day determined by your doctor. You should have regular check-ups, including ultrasound scans and hormone tests, to monitor your response and detect any problems early. Avoid driving or operating heavy machinery if you experience blurred vision or dizziness. Inform your doctor if you are pregnant or planning to become pregnant. Do not breastfeed while taking this medicine. Keep this medicine out of reach of children. Store it at room temperature, away from moisture and direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

This medicine is not intended for use in elderly women beyond reproductive age. Safety and efficacy have not been established.

🤰 Pregnancy Planning (TTC)

This medicine is used to induce ovulation in women trying to conceive. It should be stopped once pregnancy is confirmed. If you are planning pregnancy, discuss the risks and benefits with your doctor.

🏥 Post-Surgery Considerations

There are no specific restrictions after surgery, but inform your surgeon and anesthesiologist that you are taking this medicine.

🦷 Dental Procedures

No specific precautions for dental procedures. However, inform your dentist about all medicines you are taking.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to improve fertility outcomes.
🥗
Eat a balanced diet rich in fruits, vegetables, and whole grains.
😴
Exercise regularly to reduce stress and improve overall health.
💧
Avoid smoking and alcohol, as they can affect fertility.
🧘
Get adequate sleep to support hormonal balance.
🌞
Practice stress-reducing techniques like yoga or meditation.

🏋️ Exercise Considerations

Moderate exercise is generally safe. However, if you experience ovarian enlargement or abdominal discomfort, avoid strenuous activities and consult your doctor.

🥗 Diet Recommendations

Include omega-3 rich foods like fish and flaxseeds.
Reduce intake of processed foods and refined sugars.
Stay well hydrated by drinking plenty of water.
Eat plenty of leafy green vegetables for folic acid.

💼 Impact on Daily Work & Life

This medicine may cause visual disturbances or dizziness in some people. If affected, avoid driving or operating heavy machinery. Otherwise, it usually does not interfere with daily activities.

🛑 When to Stop This Medicine

Stop taking this medicine if you become pregnant or if you experience severe side effects such as visual disturbances or severe abdominal pain. Always consult your doctor before stopping the medicine.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of ovarian cysts and possibly ovarian cancer, although the evidence is not conclusive. Regular monitoring is required. It is generally recommended to limit the number of treatment cycles to avoid potential risks.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Letrozole

Another oral medication for ovulation induction, often used as an alternative.

Evidence: Well-established
Gonadotropins

Injectable hormones used for ovulation induction in specialist settings.

Evidence: Well-established
Lifestyle modifications

Weight loss and dietary changes can improve ovulation in some women.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, continue taking the medicine at the same local time as prescribed. Keep enough supply for the entire trip. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 32-year-old woman with polycystic ovary syndrome trying to conceive for 2 years.
She was prescribed this medicine at 100 mg daily for 5 days starting on day 5 of her cycle. After two cycles, she ovulated and conceived. She experienced mild hot flushes and nausea, which were manageable. Regular ultrasound monitoring ensured safety.
💡 Lesson: Consistent use and monitoring can lead to successful ovulation and pregnancy even in women with PCOS.
👤 A 28-year-old woman with irregular cycles and no ovulation.
She started this medicine at 50 mg daily for 5 days. When ovulation did not occur, her doctor increased the dose to 100 mg. She ovulated in the next cycle but did not conceive. She continued treatment for three more cycles under supervision and eventually became pregnant.
💡 Lesson: Dose adjustment may be needed, and patience with regular monitoring is key to success.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Ovulation typically occurs 5 to 10 days after the last dose of a treatment cycle. Your doctor will monitor your response with ultrasound and hormone tests.

Q: Can I take this medicine if I have PCOS?

A: Yes, this medicine is often prescribed for women with polycystic ovary syndrome to induce ovulation. However, it must be used under medical supervision.

Q: What are the chances of having twins?

A: The risk of multiple pregnancies, including twins, is increased with this medicine. Your doctor will discuss this with you.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cerofene 100mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Clomiphene guarantees pregnancy.
    Fact: Clomiphene induces ovulation but does not guarantee pregnancy. Many factors affect fertility.
  • Myth: Clomiphene is safe to take without monitoring.
    Fact: Clomiphene requires regular monitoring by a fertility specialist to ensure safety and effectiveness.

🔄 Alternative Options

Generic Alternatives

  • Clomiphene citrate 100 mg tablet

Brand Alternatives

  • Clofert 100
  • Fertyl 100
  • Ovofar 100

📊 Comparison with Similar Medicines

[{"medicine":"Clomiphene","class":"SERM","primary_use":"Ovulation induction","route":"Oral"},{"medicine":"Letrozole","class":"Aromatase inhibitor","primary_use":"Ovulation induction","route":"Oral"}]

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