cerekul 1 mg/10 mg tablet
What is cerekul 1 mg/10 mg tablet used for?
Angirex Tablet (Chlordiazepoxide + Trifluoperazine) is used to treat NEURO CNS. It contains Chlordiazepoxide (1mg) + Trifluoperazine (10mg), which Chlordiazepoxide enhances GABA-A receptor activity; Trifluoperazine blocks dopam. Always consult your doctor before use. Take as prescribed.
- Generic Name: Chlordiazepoxide + Trifluoperazine
- Manufacturer: Zeus Pharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ cerekul 1 mg/10 mg tablet Uses & Benefits
๐ Drug Information
| Generic Name(s) | Chlordiazepoxide + Trifluoperazine |
| Brand Name | Angirex Tablet |
| Manufacturer | Zeus Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Benzodiazepine + Phenothiazine Antipsychotic |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Chlordiazepoxide enhances GABA-A receptor activity; Trifluoperazine blocks dopamine D2 receptors
Mechanism Steps
๐ก How to Take cerekul 1 mg/10 mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cerekul 1 mg/10 mg tablet
โ Common Side Effects
- Drowsiness
- Dizziness
- Dry mouth
- Blurred vision
- Constipation
- Weight gain
๐จ Serious Side Effects
- Extrapyramidal symptoms
- Tardive dyskinesia
- Neuroleptic malignant syndrome
- Respiratory depression
- Blood dyscrasias
โ ๏ธ Rare Side Effects
- Jaundice
- Agranulocytosis
- Seizures
- QT prolongation
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Additive CNS depression, increased sedation |
| MAOIs | Major | Hypertensive crisis, serotonin syndrome |
| CNS Depressants | Major | Enhanced sedation, respiratory depression |
| Levodopa | Major | Antagonism of levodopa effect |
| Lithium | Major | Increased neurotoxicity risk |
| Anticholinergics | Major | Additive anticholinergic effects |
| Antihypertensives | Moderate | Additive hypotensive effect |
| Antidiabetics | Moderate | Altered blood glucose control |
| CYP3A4 Inhibitors | Moderate | Increased chlordiazepoxide levels |
| CYP3A4 Inducers | Moderate | Decreased chlordiazepoxide levels |
| Antacids | Minor | Reduced absorption of trifluoperazine |
| Caffeine | Minor | Reduced sedative effect |
๐จ Major Interactions
- MAOIs
- CNS depressants (alcohol, opioids)
- Anticholinergics
- Levodopa
- Lithium
โก Moderate Interactions
- Antihypertensives
- Antidiabetics
- CYP3A4 inhibitors/inducers
โน๏ธ Minor Interactions
- Antacids
- Caffeine
๐ฝ๏ธ Food Interactions
Grapefruit juice (may increase levels), High-fat meals (may delay absorption)
๐ท Alcohol Interaction
Avoid; additive CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, coma, severe CNS depression, narrow-angle glaucoma, bone marrow suppression, liver failure
๐ Monitoring Parameters
CNS status, liver function, blood pressure, ECG (QT interval), CBC
๐คฑ Lactation Safety
Not recommended; excreted in breast milk
๐ Overdose Management
Supportive care; activated charcoal; flumazenil for chlordiazepoxide; avoid epinephrine for hypotension
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double
๐จโโ๏ธ Reviewed by Expert
โญ User Reviews
This medicine was effective for me. I followed the doctor's advice.
Good quality medicine. Satisfied with the outcome.
Good quality medicine. Satisfied with the outcome.
Helpful and effective medicine as per my experience. Always consult a doctor.
Found this to be a helpful product. Good results.