cepoxim 200mg tablet - Cefpodoxime Proxetil (200mg) medicine

cepoxim 200mg tablet

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🏭 Syntho Pharmaceuticals Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 21, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Reviewed by
SaathiMed Expert Panel | Sep 21, 2026

What is cepoxim 200mg tablet used for?

This medicine contains Cefpodoxime Proxetil (200mg) and is used to treat ANTI INFECTIVES. Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to . Always consult your doctor before use.

  • Generic Name: Cefpodoxime Proxetil
  • Manufacturer: Syntho Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Category A
  • Prescription Required: Yes
💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 cepoxim 200mg tablet Uses & Benefits

Treatment of respiratory tract infections (e.g., community-acquired pneumonia, acute exacerbations of chronic bronchitis), urinary tract infections, skin and soft tissue infections, otitis media, sinusitis, and uncomplicated gonorrhea.

Off-label uses: Lyme disease, Meningococcal prophylaxis, Bacterial endocarditis prophylaxis

📋 Drug Information

Generic Name(s)Cefpodoxime Proxetil
Brand NameAxone O 200mg Tablet
ManufacturerSyntho Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 3 generation
Route of AdministrationOral
StorageStore at 20-25°C (68-77°F); protect from light and moisture.
Shelf LifeAs per manufacturer

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionWell absorbed from gastrointestinal tract; absorption is enhanced by food.
DistributionDistributes widely into body tissues and fluids including lungs, tonsils, prostate, and middle ear; crosses placenta and enters breast milk.
Protein BindingAbout 21-29% bound to plasma proteins.
MetabolismCefpodoxime proxetil is de-esterified to active cefpodoxime; further metabolism is minimal.
Half-LifeApproximately 2-3 hours in patients with normal renal function.
ExcretionPrimarily excreted unchanged in urine via glomerular filtration and tubular secretion.
BioavailabilityApproximately 50% (increased to 60-70% when taken with food).
Onset of ActionRapid; within 1-2 hours after oral administration.
Peak Plasma Time2-3 hours after oral administration.
Duration of ActionApproximately 12 hours.

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), leading to cell lysis and death.

Mechanism Steps

1Cefpodoxime proxetil is de-esterified by intestinal esterases to active cefpodoxime.
2Cefpodoxime binds to penicillin-binding proteins (PBPs) located on the bacterial cell wall.
3Inhibition of transpeptidase enzymes prevents cross-linking of peptidoglycan chains.
4Disruption of cell wall synthesis leads to osmotic instability and bacterial cell lysis.
5Bactericidal effect is time-dependent, requiring adequate drug concentration above MIC for a sufficient duration.

💡 How to Take cepoxim 200mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of cepoxim 200mg tablet

✅ Common Side Effects

Diarrhea
Nausea
Vomiting
Abdominal pain
Headache
Vaginal candidiasis

🚨 Serious Side Effects

Pseudomembranous colitis
Severe allergic reactions (anaphylaxis)
Stevens-Johnson syndrome
Toxic epidermal necrolysis
Seizures

⚠️ Rare Side Effects

Hemolytic anemia
Agranulocytosis
Thrombocytopenia
Interstitial nephritis
Hepatitis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Probenecid Major Decreased renal excretion of cefpodoxime, increased plasma levels and toxicity risk.
Warfarin Major Enhanced anticoagulant effect, increased INR and bleeding risk.
Live typhoid vaccine Major Reduced immunogenicity of the vaccine.
BCG vaccine Moderate Reduced effectiveness of BCG vaccine.
Cholera vaccine Moderate Reduced immune response to cholera vaccine.
Estrogen derivatives Moderate Possible reduced efficacy of oral contraceptives.
Sodium picosulfate Moderate Increased risk of Clostridium difficile infection.
Antacids Minor Reduced absorption of cefpodoxime.
H2-receptor antagonists Minor Reduced absorption of cefpodoxime.
Iron supplements Minor Reduced absorption of cefpodoxime.

🚨 Major Interactions

  • Probenecid
  • Warfarin
  • Live typhoid vaccine

⚡ Moderate Interactions

  • BCG vaccine
  • Cholera vaccine
  • Estrogen derivatives
  • Sodium picosulfate

🍷 Alcohol Interaction

No direct interaction reported; however, alcohol may reduce immune response and increase side effects.

🛡️ Safety & Warnings

🚫 Contraindications

Hypersensitivity to cefpodoxime or other cephalosporins; history of immediate-type hypersensitivity to penicillins.

🤱 Lactation Safety

Excreted in breast milk in small amounts; use with caution.

💊 Overdose Management

Supportive care; hemodialysis may enhance elimination.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose and resume regular schedule. Do not double dose.

🔄 Substitutes for cepoxim 200mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

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