celstemx 24mg injection - Plerixafor (24mg) medicine

celstemx 24mg injection

4.5 (11 reviews)
๐Ÿญ Sayre Therapeutics Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is celstemx 24mg injection used for?

Celrixafor (Plerixafor) is used to treat ANTI NEOPLASTICS. It contains Plerixafor (24mg), which Plerixafor is a CXCR4 chemokine receptor antagonist; it blocks the binding of st. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Plerixafor
  • Manufacturer: Sayre Therapeutics Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š celstemx 24mg injection Uses & Benefits

Mobilization of hematopoietic stem cells for autologous transplantation in patients with non-Hodgkin's lymphoma or multiple myeloma.

Off-label uses: Mobilization for allogeneic transplantation; treatment of WHIM syndrome (rare immunodeficiency).

๐Ÿ“‹ Drug Information

Generic Name(s)Plerixafor
Brand NameCelrixafor
ManufacturerSayre Therapeutics Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassHematopoietic stem cell mobilizer
Route of AdministrationSubcutaneous injection
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light; do not freeze.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after subcutaneous injection; peak plasma concentration reached in 30-60 minutes.
DistributionVolume of distribution approximately 0.3 L/kg; primarily distributed in extracellular fluid.
Protein BindingApproximately 58% bound to plasma proteins.
MetabolismMinimally metabolized; primarily excreted unchanged.
Half-Life3-5 hours in healthy volunteers; prolonged in renal impairment.
ExcretionPrimarily excreted unchanged in urine (approximately 70% within 24 hours).
BioavailabilityHigh (approximately 87% after subcutaneous injection).
Onset of ActionRapid; mobilization of stem cells begins within 1-2 hours.
Peak Plasma Time30-60 minutes after subcutaneous injection.
Duration of ActionUp to 24 hours; stem cell mobilization persists for several hours.

How It Works

Plerixafor is a CXCR4 chemokine receptor antagonist; it blocks the binding of stromal cell-derived factor-1ฮฑ (SDF-1ฮฑ) to CXCR4, resulting in mobilization of hematopoietic stem cells from bone marrow to peripheral blood.

Mechanism Steps

1Plerixafor binds to CXCR4 receptor on hematopoietic stem cells.
2Blocks interaction between CXCR4 and SDF-1ฮฑ.
3Disrupts retention signals that keep stem cells in bone marrow.

๐Ÿ’ก How to Take celstemx 24mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of celstemx 24mg injection

โœ… Common Side Effects

  • Injection site reactions
  • Diarrhea
  • Nausea
  • Fatigue
  • Headache
  • Arthralgia
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Anaphylactic reactions
  • Splenic rupture
  • Leukocytosis
  • Thrombocytopenia
  • Tumor cell mobilization in leukemia

โš ๏ธ Rare Side Effects

  • Hypersensitivity vasculitis
  • Pulmonary embolism
  • Seizures

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased risk of bleeding due to additive effects on hemostasis.
Heparin Major Increased risk of bleeding.
NSAIDs Moderate Increased risk of gastrointestinal bleeding.
Aspirin Moderate Increased risk of bleeding.
Clopidogrel Moderate Increased risk of bleeding.

๐Ÿšจ Major Interactions

  • Warfarin
  • Heparin
  • Anticoagulants

โšก Moderate Interactions

  • NSAIDs
  • Aspirin
  • Clopidogrel

โ„น๏ธ Minor Interactions

  • Acetaminophen
  • Corticosteroids

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No known interaction; caution due to potential for dizziness.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to plerixafor or any excipients; patients with leukemia (may cause mobilization of leukemic cells).

๐Ÿ“Š Monitoring Parameters

Complete blood count (CBC) with differential; CD34+ cell count; renal function; signs of bleeding or infection.

๐Ÿคฑ Lactation Safety

Not recommended; unknown if excreted in human milk.

๐Ÿ’Š Overdose Management

No specific antidote; supportive care; monitor for adverse effects.

โฐ Missed Dose

Administer as soon as remembered if within 4 hours; otherwise skip and resume next scheduled dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for celstemx 24mg injection

View All

Alternative brands with exact same active ingredient (Plerixafor (24mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Happy Patient Jul 10, 2026

Effective and reliable. Worked as expected.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Happy Patient Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

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