Cefaro CV 250mg/62.5mg Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe or persistent diarrhea, or blood in stool
- Yellowing of the skin or eyes
- Unusual bleeding or bruising
- Decreased urine output or swelling in the legs
- Severe abdominal pain
- High fever with rash
If experiencing severe symptoms, call emergency services immediately.
What is cefuxime-cv 250mg/62.5mg tablet used for?
This medicine is a combination antibiotic containing cefuroxime and clavulanic acid, used to treat various bacterial infections. It works by killing bacteria and overcoming resistance. Take it with food as prescribed.
- Generic Name: Cefuroxime + Clavulanic Acid
- Manufacturer: Nectar Biopharma Pvt Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefuxime-cv 250mg/62.5mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा सेफुरोक्सिम और क्लैवुलैनिक एसिड का संयोजन है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह श्वसन तंत्र, मूत्र मार्ग, त्वचा और कोमल ऊतकों के संक्रमण में प्रभावी है। यह जीवाणुओं को मारती है और उनके प्रतिरोध को कम करती है। इसे भोजन के साथ लें और डॉक्टर के निर्देशानुसार पूरा कोर्स करें।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द, सिरदर्द और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, गंभीर दस्त, यकृत समस्याएं और रक्त विकार हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। इसे भोजन के साथ लें। गोली को पूरा निगलें, चबाएं नहीं। यदि खुराक छूट जाए तो याद आते ही लें, लेकिन अगली खुराक का समय नजदीक हो तो छोड़ दें। शराब न लें। गुर्दे या यकृत की समस्या हो तो डॉक्टर को बताएं।
💊 cefuxime-cv 250mg/62.5mg tablet Uses & Benefits
[{"condition":"Respiratory tract infections","description":"Used to treat community-acquired pneumonia, acute bacterial exacerbations of chronic bronchitis, and acute bacterial sinusitis caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated and complicated urinary tract infections caused by susceptible bacteria such as Escherichia coli and Klebsiella species.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for uncomplicated skin infections including cellulitis, abscesses, and wound infections caused by susceptible gram-positive and gram-negative bacteria.","evidence":"Well-established"},{"condition":"Gonorrhea","description":"May be used as an alternative treatment for uncomplicated gonorrhea caused by Neisseria gonorrhoeae, though resistance patterns should be considered.","evidence":"Moderate"},{"condition":"Lyme disease","description":"Used in the treatment of early Lyme disease and some manifestations of late Lyme disease, though other agents may be preferred.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Prophylaxis in dental procedures","description":"Sometimes used off-label for prevention of infective endocarditis in high-risk patients undergoing dental procedures, but not a standard recommendation.","evidence":"Limited"},{"condition":"Travelers' diarrhea","description":"Occasionally prescribed off-label for moderate to severe travelers' diarrhea, but fluoroquinolones or azithromycin are more commonly used.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Skin and soft tissue infections, Gonorrhea, Lyme disease
📋 Drug Information
| Generic Name(s) | Cefuroxime + Clavulanic Acid |
| Brand Name | Augxetil CV 500 Tablet |
| Manufacturer | Nectar Biopharma Pvt Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin antibiotic + Beta-lactamase inhibitor |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefuroxime, the active cephalosporin component, inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins, which interferes with the cross-linking of peptidoglycan strands. This leads to weakening of the cell wall and ultimately bacterial lysis and death. Clavulanic acid is a beta-lactamase inhibitor that binds irreversibly to certain beta-lactamase enzymes produced by bacteria, preventing them from hydrolyzing and inactivating cefuroxime. This extends the spectrum of cefuroxime to include beta-lactamase-producing strains of bacteria that would otherwise be resistant.
Mechanism Steps
💡 How to Take cefuxime-cv 250mg/62.5mg tablet
Strength: Immediate-release tablet containing 250 mg cefuroxime and 62.5 mg clavulanic acid.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken orally twice daily, approximately every 12 hours, with food. The duration of treatment depends on the type and severity of infection, typically 5 to 10 days. For specific infections such as uncomplicated urinary tract infections, a shorter course may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may have reduced renal function and may require dose adjustment. Use with caution and monitor renal function. Dose must be individualized by a qualified clinician. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For creatinine clearance between 10 and 30 mL/min, the usual dose may be reduced or the dosing interval extended. For creatinine clearance less than 10 mL/min, the drug should be used with caution and may require further dose reduction. Consult a nephrologist or clinical pharmacist for specific guidance. |
| Hepatic Impairment | No specific dose adjustment is provided for hepatic impairment, but caution is advised in patients with severe liver disease. Monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose is 500 mg of cefuroxime (two tablets) per day, but this may vary based on indication and medical supervision. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefuxime-cv 250mg/62.5mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Probenecid | Major | |
| Oral contraceptives | Moderate | |
| Loop diuretics | Moderate | |
| Aminoglycosides | Moderate | |
| Methotrexate | Moderate | |
| Antacids | Minor | |
| H2 blockers | Minor |
🚨 Major Interactions
- Warfarin
- Probenecid
- Oral contraceptives
⚡ Moderate Interactions
- Loop diuretics (e.g., furosemide)
- Aminoglycosides
- Methotrexate
🍷 Alcohol Interaction
Alcohol may worsen gastrointestinal side effects such as nausea and diarrhea. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cefuroxime, clavulanic acid, or any other cephalosporin or beta-lactam antibiotic","History of severe allergic reaction (e.g., anaphylaxis) to penicillins or other beta-lactam antibiotics","Use in patients with a history of Clostridioides difficile-associated diarrhea"]
⚠️ Warnings & Precautions
["Before starting therapy, inquire about previous allergic reactions to antibiotics.","Use with caution in patients with renal impairment; dose adjustment may be required.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","May cause false-positive results in urine glucose tests using copper reduction methods.","Not effective against viral infections; do not use for colds or flu.","Avoid use in patients with a history of colitis."]
🤱 Lactation Safety
Cefuroxime is excreted in human breast milk in small amounts. Clavulanic acid is also excreted in breast milk. The amounts are generally low and unlikely to cause harm to the nursing infant, but monitor for diarrhea or thrush. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, and diarrhea. In severe cases, seizures may occur, especially in patients with renal impairment. Treatment is symptomatic and supportive. Hemodialysis may be considered to remove cefuroxime from the blood in severe cases. Contact a poison control center or emergency department immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at once to make up for a missed dose.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop treatment early, even if you feel better, as this can lead to antibiotic resistance and recurrence of infection. Take the tablet with food to improve absorption and reduce stomach upset. Swallow the tablet whole with a glass of water; do not crush or chew it. If you miss a dose, take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose. Inform your doctor if you have kidney problems, liver disease, or a history of allergies to antibiotics. Avoid alcohol while taking this medicine, as it may worsen side effects. Do not share this medicine with others, even if they have similar symptoms. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced renal function and may require dose adjustment. Monitor renal function and watch for signs of superinfection.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. It is generally considered safe but should be used only when clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions regarding dosing and duration.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may be used prophylactically before dental procedures in certain high-risk patients, but this is not a standard recommendation.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Mild exercise is generally safe, but if you experience dizziness, fatigue, or severe diarrhea, avoid strenuous activities and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating heavy machinery until you know how it affects you. Most people can continue their normal activities.
🛑 When to Stop This Medicine
Stop taking this medicine only after completing the full prescribed course or if your doctor advises discontinuation. If you experience severe side effects, contact your doctor immediately before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, superinfections (such as oral thrush or vaginal yeast infections), and rarely, liver or kidney problems. Prolonged therapy should be monitored with regular blood tests. Use only for the prescribed duration.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Another combination antibiotic that may be used for similar infections.
Evidence: Well-establishedMay be used if beta-lactamase-producing bacteria are not suspected.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for a live vaccine, inform your doctor as antibiotics may affect the vaccine's effectiveness.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from moisture. If crossing time zones, adjust dosing times gradually to maintain approximately 12-hour intervals. Check local customs regulations regarding prescription medications.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2 to 3 days, but it is important to complete the full course as prescribed.
A: Yes, take it with food to improve absorption and reduce stomach upset.
A: Take it as soon as you remember, but if it is almost time for your next dose, skip the missed dose and continue with your regular schedule.
A: Consult your doctor. It is generally considered safe when clearly needed, but the combination with clavulanic acid has not been extensively studied.
A: It is advisable to avoid alcohol as it may worsen side effects like nausea and diarrhea.
🤔 Common Patient Concerns
🔄 Substitutes for cefuxime-cv 250mg/62.5mg tablet
View AllAlternative brands with exact same active ingredient:
-
meritum cv 250mg/62.5mg tabletMRG Biotech Pvt Ltd ₹70.00 40.7% CHEAPER
-
pulmocef-cv 250 tabletMicro Labs Ltd ₹121.88 3.2% COSTLIER
-
bactilam 250mg/62.5mg tabletEmcure Pharmaceuticals Ltd ₹128.81 9% COSTLIER
-
ocef cv 250 mg/62.5 mg tabletGujarat Terce Laboratories Ltd ₹141.56 19.8% COSTLIER
-
vartil cv 250mg/62.5mg tabletVarmed Pharma Pvt Ltd ₹180.00 52.4% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine is effective only against bacterial infections and will not treat viral illnesses. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full prescribed course to prevent recurrence and antibiotic resistance. - Myth: Antibiotics can be shared with others who have similar symptoms.
Fact: Never share antibiotics; they are prescribed for a specific individual and condition.
🔄 Alternative Options
Generic Alternatives
- Cefuroxime and clavulanic acid combination tablets are available generically.
Brand Alternatives
- Cefaro CV 250mg/62.5mg Tablet is a brand of this medicine.