cefticool 1000mg injection - Ceftizoxime (1000mg) medicine

cefticool 1000mg injection - Uses, Price, Side Effects & Substitutes

No reviews yet
๐Ÿญ Unifaith Biotech (P) Limited ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 27, 2026

What is cefticool 1000mg injection used for?

Cefizox (Ceftizoxime) is used to treat ANTI INFECTIVES. It contains Ceftizoxime (1000mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Ceftizoxime
  • Manufacturer: Unifaith Biotech (P) Limited
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š cefticool 1000mg injection Uses & Benefits

Treatment of infections caused by susceptible organisms: lower respiratory tract, urinary tract, skin and soft tissue, bone and joint, intra-abdominal, gynecologic, septicemia, meningitis.

Off-label uses: Lyme disease, Typhoid fever, Melioidosis

๐Ÿ“‹ Drug Information

Generic Name(s)Ceftizoxime
Brand NameCefizox
ManufacturerUnifaith Biotech (P) Limited
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassCephalosporins: 3 generation
Route of AdministrationIntravenous (IV) or intramuscular (IM).
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light; reconstituted solutions stable for 24 hours at room temperature, 7 days refrigerated.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntramuscular administration: well absorbed; intravenous administration: immediate.
DistributionWidely distributed into body tissues and fluids including pleural, peritoneal, and synovial fluids; crosses placenta; minimal penetration into CSF.
Protein BindingApproximately 30%
MetabolismNot significantly metabolized; primarily excreted unchanged.
Half-Life1.4-1.8 hours (normal renal function); prolonged in renal impairment.
ExcretionRenal excretion (80-90% unchanged) via glomerular filtration and tubular secretion.
Bioavailability100% (IV); approximately 90% (IM).
Onset of ActionRapid (within 1 hour for IM).
Peak Plasma TimeIM: 0.5-1 hour; IV: end of infusion.
Duration of ActionApproximately 12 hours.

How It Works

Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs), inhibiting transpeptidase activity, leading to cell lysis.

Mechanism Steps

1Ceftizoxime binds to penicillin-binding proteins (PBPs) on bacterial cell wall.
2Inhibits transpeptidase enzyme, preventing cross-linking of peptidoglycan chains.
3Disrupts cell wall synthesis, leading to osmotic instability and cell lysis.

๐Ÿ’ก How to Take cefticool 1000mg injection

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cefticool 1000mg injection

โœ… Common Side Effects

  • Diarrhea
  • Nausea
  • Vomiting
  • Rash
  • Injection site pain
  • Eosinophilia

๐Ÿšจ Serious Side Effects

  • Anaphylaxis
  • Pseudomembranous colitis
  • Seizures
  • Severe skin reactions (Stevens-Johnson syndrome)
  • Hemolytic anemia

โš ๏ธ Rare Side Effects

  • Interstitial nephritis
  • Hepatotoxicity
  • Agranulocytosis
  • Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Probenecid Major Decreased renal excretion of ceftizoxime, increased serum levels
Aminoglycosides Major Increased nephrotoxicity risk
Loop diuretics Moderate Increased nephrotoxicity risk
Oral contraceptives Moderate Reduced contraceptive efficacy
Antacids Minor Possible decreased absorption
Iron supplements Minor Possible decreased absorption

๐Ÿšจ Major Interactions

  • Warfarin
  • Probenecid
  • Aminoglycosides

โšก Moderate Interactions

  • Loop diuretics
  • Oral contraceptives

โ„น๏ธ Minor Interactions

  • Antacids
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

No disulfiram-like reaction reported.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to ceftizoxime or other cephalosporins, penicillins, or beta-lactam antibiotics.

๐Ÿ“Š Monitoring Parameters

Renal function (especially in elderly or with concurrent nephrotoxic drugs), signs of hypersensitivity, superinfection, bleeding (with warfarin).

๐Ÿคฑ Lactation Safety

Excreted in breast milk in low concentrations; generally considered compatible with breastfeeding.

๐Ÿ’Š Overdose Management

Supportive care; hemodialysis may enhance elimination.

โฐ Missed Dose

Administer as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cefticool 1000mg injection

View All

Alternative brands with exact same active ingredient (Ceftizoxime (1000mg)):

Medical Note: Always consult your doctor before switching medications.

๐Ÿ˜Š Was this information helpful?

Browse Medicines A-Z

Search our extensive medical database alphabetically.

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory
SaathiMed App
SaathiMed App Consult doctors & order medicines faster
Install