Aricef DS Syrup: Complete Guide to Uses, Dosage, and Safety
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling of face or throat, difficulty breathing.
- Severe diarrhea with abdominal cramps or fever, which may indicate Clostridium difficile infection.
- Seizures, especially in patients with kidney disease.
- Unusual bruising or bleeding, which may indicate a blood disorder.
- Decreased urine output or swelling, which may indicate kidney problems.
- Yellowing of skin or eyes, which may indicate liver problems.
- Persistent headache or dizziness that interferes with daily activities.
If experiencing severe symptoms, call emergency services immediately.
What is cefolac 50mg oral suspension used for?
This medicine is an antibiotic syrup containing cefixime, used to treat bacterial infections such as respiratory tract infections, urinary tract infections, and skin infections. It works by killing bacteria and is usually taken for 7 to 10 days.
- Generic Name: Cefixime
- Manufacturer: Macleods Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefolac 50mg oral suspension के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीबायोटिक सिरप है जिसमें सेफिक्साइम नामक सक्रिय तत्व होता है। यह मुख्य रूप से बैक्टीरियल संक्रमणों के इलाज के लिए उपयोग की जाती है, जैसे कि श्वसन तंत्र के संक्रमण, मूत्र मार्ग के संक्रमण, त्वचा के संक्रमण और गोनोरिया। यह दवा बैक्टीरिया को मारकर काम करती है और आमतौर पर 7 से 10 दिनों तक ली जाती है। इसका उपयोग वायरल संक्रमणों जैसे सर्दी-जुकाम के लिए नहीं किया जाना चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और सिरदर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभावों में एलर्जी की प्रतिक्रिया, जैसे चकत्ते, खुजली, चेहरे या गले में सूजन, और सांस लेने में कठिनाई शामिल हो सकती है। दवा के लंबे समय तक उपयोग से क्लोस्ट्रीडियम डिफिसाइल से जुड़े दस्त भी हो सकते हैं। यदि आपको कोई गंभीर या लगातार दुष्प्रभाव महसूस हो, तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले, अपने डॉक्टर को बताएं कि क्या आपको सेफिक्साइम, अन्य सेफलोस्पोरिन या पेनिसिलिन से एलर्जी है। साथ ही, किडनी रोग, यकृत रोग या जठरांत्र संबंधी समस्याओं के बारे में भी जानकारी दें। इस दवा को वायरल संक्रमणों के इलाज के लिए न लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें। यदि आप एक खुराक भूल जाते हैं, तो याद आते ही ले लें, लेकिन अगली खुराक का समय नजदीक हो तो छोड़ दें। दोहरी खुराक न लें।
💊 cefolac 50mg oral suspension Uses & Benefits
- [{"condition":"Respiratory tract infections","description":"Used to treat bacterial infections of the respiratory tract, such as bronchitis and pneumonia, caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated urinary tract infections caused by susceptible bacteria like E.
- coli and Klebsiella species.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Used for treating bacterial skin infections such as cellulitis and abscesses caused by susceptible strains.","evidence":"Well-established"},{"condition":"Uncomplicated gonorrhea","description":"A single dose is often used to treat uncomplicated gonorrhea caused by Neisseria gonorrhoeae.","evidence":"Well-established"},{"condition":"Otitis media","description":"Sometimes prescribed for middle ear infections in children, though other antibiotics may be preferred.","evidence":"Moderate"},{"condition":"Pharyngitis and tonsillitis","description":"May be used for bacterial pharyngitis or tonsillitis, particularly when penicillin is not suitable.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Lyme disease","description":"Occasionally used as an alternative for early Lyme disease, but not first-line.","evidence":"Limited"},{"condition":"Prophylaxis in dental procedures","description":"Rarely used for prophylaxis in patients with certain heart conditions, but not standard.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Respiratory tract infections, Urinary tract infections, Skin infections, Gonorrhea
📋 Drug Information
| Generic Name(s) | Cefixime |
| Brand Name | Abixim |
| Manufacturer | Macleods Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Oral |
| Storage | Store the dry powder at room temperature (15-30°C) in a tightly closed container. After reconstitution, store the syrup in the refrigerator (2-8°C) and use within 14 days. Do not freeze. |
| Shelf Life | The shelf life of the dry powder is typically 2 years from the date of manufacture. After reconstitution, the syrup should be used within 14 days if stored in the refrigerator. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by binding to specific penicillin-binding proteins (PBPs) located inside the bacterial cell wall. This binding inhibits the third and final stage of bacterial cell wall synthesis, leading to a defective cell wall and ultimately causing bacterial cell lysis and death. It is bactericidal against a wide range of gram-positive and gram-negative bacteria.
Mechanism Steps
💡 How to Take cefolac 50mg oral suspension
Strength: This medicine is available as a dry syrup that provides 50 mg of cefixime per 5 mL after reconstitution.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 200-400 mg per day, taken as a single dose or in two divided doses, depending on the type and severity of the infection. For uncomplicated gonorrhea, a single 400 mg dose is recommended. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | The usual pediatric dose of this medicine is 8 mg/kg/day, taken as a single dose or in two divided doses. For children over 50 kg or older than 12 years, adult dosing may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Elderly Dosage | Elderly patients may have reduced renal function and may require dose adjustment. Dose must be individualized by a qualified clinician based on renal function. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For creatinine clearance (CrCl) 20-60 mL/min, the dose should be reduced to 75% of the usual dose. For CrCl <20 mL/min, the dose should be reduced to 50% of the usual dose. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | No specific dose adjustment is required for hepatic impairment, but caution is advised. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 400 mg. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefolac 50mg oral suspension
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Carbamazepine | Major | |
| Probenecid | Moderate | |
| Antacids | Moderate | |
| H2 blockers | Moderate | |
| Proton pump inhibitors | Moderate | |
| Oral contraceptives | Minor | |
| Loop diuretics | Minor |
🚨 Major Interactions
- Warfarin
- Carbamazepine
- Probenecid
⚡ Moderate Interactions
- Antacids (aluminum or magnesium based)
- H2 blockers (e.g., ranitidine)
- Proton pump inhibitors (e.g., omeprazole)
🍷 Alcohol Interaction
Alcohol may increase the risk of stomach upset and dizziness. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to cefixime or any other cephalosporin","Previous anaphylactic reaction to penicillins","Severe renal impairment (dose adjustment required)","Use in premature infants or neonates (safety not established)"]
⚠️ Warnings & Precautions
["Before starting this medicine, tell your doctor if you are allergic to penicillins or cephalosporins.","Use with caution in patients with kidney disease; dose adjustment may be needed.","Prolonged use may lead to overgrowth of non-susceptible organisms, causing superinfection.","May cause Clostridium difficile-associated diarrhea; report severe diarrhea.","Do not use this medicine for viral infections.","Complete the full course as prescribed, even if symptoms improve.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]
🤱 Lactation Safety
This medicine is excreted in human breast milk in small amounts. It is generally considered safe during breastfeeding, but consult your doctor to weigh the benefits and risks.
💊 Overdose Management
Overdose of this medicine may cause nausea, vomiting, abdominal pain, and diarrhea. In severe cases, seizures may occur, especially in patients with renal impairment. Treatment is symptomatic and supportive. Hemodialysis may be considered in severe cases. Contact a poison control center or emergency room immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you are allergic to cefixime, other cephalosporins, or penicillins. Also, disclose any history of kidney disease, liver disease, or gastrointestinal problems, especially colitis. This medicine may interact with other medications, including blood thinners, antacids, and certain antibiotics, so provide a complete list of all medicines you are taking. Do not use this medicine to treat viral infections, as it will not work and may cause harm. Take the full prescribed course, even if you feel better, to prevent resistance. If you miss a dose, take it as soon as you remember, but skip it if it is almost time for the next dose; do not double the dose. Store the dry powder at room temperature and after reconstitution, keep the syrup in the refrigerator and discard any unused portion after 14 days. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may have reduced kidney function and may require dose adjustment. They are also more susceptible to side effects like diarrhea and dizziness. Close monitoring is advised.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is classified as Pregnancy Category B, meaning it is generally considered safe, but should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed after surgery to prevent or treat bacterial infections. Follow your surgeon's instructions carefully and complete the full course.
🦷 Dental Procedures
This medicine may be used for dental infections or prophylaxis in certain patients. Inform your dentist if you are taking this medicine before any dental procedure.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine may cause dizziness or fatigue. Avoid strenuous exercise or activities requiring alertness until you know how it affects you.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue, which can affect your ability to drive or operate machinery. It is advisable to avoid these activities until you know how the medicine affects you. Most people can continue their normal daily activities with caution.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the full course, even if you feel better. Stopping early can lead to antibiotic resistance and recurrence of the infection. If you experience severe side effects, consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use can lead to antibiotic resistance, superinfections, and rare blood or kidney disorders. Regular monitoring of kidney and liver function may be required if used for extended periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the infection and susceptibility, other antibiotics like amoxicillin or cefpodoxime may be used.
Evidence: Well-establishedFor viral infections, rest, fluids, and over-the-counter remedies may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for a vaccine, inform your doctor, as antibiotics may be prescribed for an active infection that could affect vaccination timing.
📦 Storage Guide
✅ DO
Store dry powder at room temperature (15-30°C)
❌ DON'T
Do not refrigerate dry powder
✅ DO
After reconstitution, store in refrigerator (2-8°C)
❌ DON'T
Do not freeze the reconstituted syrup
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling with this medicine, carry it in its original packaging along with a copy of your prescription. Keep the dry powder at room temperature and protect it from extreme heat or moisture. If the syrup is already reconstituted, keep it refrigerated and use within 14 days. For air travel, carry it in your hand luggage to avoid temperature extremes in checked baggage. Check customs regulations for carrying prescription medicines in your destination country.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take this medicine with or without food. Taking it with food may help reduce stomach upset.
A: Take the missed dose as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Yes, this medicine is commonly prescribed for children, but the dose is based on weight and must be determined by a doctor.
A: No, you must complete the full course to prevent the infection from returning and to avoid antibiotic resistance.
🤔 Common Patient Concerns
🔄 Substitutes for cefolac 50mg oral suspension
View AllAlternative brands with exact same active ingredient:
-
cefimax 50mg dry syrupWin-Medicare Pvt Ltd ₹11.53 78.7% CHEAPER
-
fexim o 50mg dry syrupZydus Healthcare Limited ₹16.41 69.7% CHEAPER
-
fiximac syrupTorque Pharmaceuticals Pvt Ltd ₹18.16 66.4% CHEAPER
-
safexim 50mg dry syrupShreya Life Sciences Pvt Ltd ₹18.75 65.4% CHEAPER
-
nirxime 50mg syrupNirlife Healthcare ₹18.97 64.9% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: Antibiotics only work against bacterial infections. They are ineffective against viruses. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full course to prevent the infection from returning and to avoid antibiotic resistance. - Myth: Antibiotics can be shared with others.
Fact: Antibiotics are prescribed for specific infections and should never be shared.
🔄 Alternative Options
Generic Alternatives
- Cefixime 50mg/5mL dry syrup
Brand Alternatives
- Taxim-O 50 Dry Syrup
- Zifi 50 Dry Syrup
- Cefolac 50 Dry Syrup