Cefton-S 1.5gm Injection: A Comprehensive Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or swelling of the face, lips, or throat
- Severe, persistent, or bloody diarrhea
- Rash with blistering or peeling skin
- Seizures or confusion
- Decreased urine output or swelling in legs
- Yellowing of eyes or skin
- Severe abdominal pain radiating to the back
If experiencing severe symptoms, call emergency services immediately.
What is cefmol-sf 1gm/0.5gm injection used for?
This medicine is a combination antibiotic containing ceftriaxone and sulbactam, used intravenously to treat serious bacterial infections. It works by killing bacteria and overcoming resistance.
- Generic Name: Ceftriaxone + Sulbactam
- Manufacturer: Elfin Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefmol-sf 1gm/0.5gm injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्ट्रिएक्सोन और सल्बैक्टम का संयोजन है, जिसका उपयोग गंभीर जीवाणु संक्रमणों के इलाज के लिए अंतःशिरा (IV) मार्ग से किया जाता है। यह निमोनिया, मूत्र पथ के संक्रमण, पेट के अंदर के संक्रमण, त्वचा के संक्रमण और मेनिनजाइटिस जैसी बीमारियों में प्रभावी है। यह दवा बैक्टीरिया की कोशिका भित्ति को नष्ट करके उन्हें मार देती है और सल्बैक्टम एंजाइम को रोकता है जो सेफ्ट्रिएक्सोन को निष्क्रिय कर सकता है। यह केवल डॉक्टर की देखरेख में अस्पताल में दी जाती है।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन स्थल पर दर्द, दस्त, मतली, उल्टी और त्वचा पर चकत्ते शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, गंभीर दस्त, रक्त विकार, यकृत और गुर्दे की समस्याएं हो सकती हैं। यदि आपको सांस लेने में कठिनाई, चेहरे या गले में सूजन, या गंभीर दस्त हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: यह दवा केवल योग्य स्वास्थ्य पेशेवर द्वारा ही दी जानी चाहिए। स्वयं इंजेक्शन न लगाएं। अपने डॉक्टर को अपनी सभी चिकित्सीय स्थितियों, दवाओं और एलर्जी के बारे में बताएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। इलाज के दौरान शराब न पिएं। दवा का पूरा कोर्स पूरा करें, बीच में न छोड़ें। किसी भी असामान्य लक्षण की रिपोर्ट डॉक्टर को करें।
💊 cefmol-sf 1gm/0.5gm injection Uses & Benefits
[{"condition":"Community-acquired pneumonia","description":"Used to treat moderate to severe pneumonia caused by susceptible bacteria, often when beta-lactamase-producing organisms are suspected.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"Effective against pyelonephritis and other complicated UTIs caused by susceptible Gram-negative bacteria.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Used in combination with other antibiotics for intra-abdominal infections like peritonitis and abscesses.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats severe cellulitis, abscesses, and wound infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Meningitis","description":"Used for bacterial meningitis when caused by susceptible strains, often in combination with other agents.","evidence":"Well-established"},{"condition":"Surgical prophylaxis","description":"Administered before certain surgical procedures to prevent postoperative infections.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Lyme disease","description":"Sometimes used off-label for disseminated Lyme disease, though other agents are preferred.","evidence":"Limited"},{"condition":"Gonorrhea","description":"May be used off-label for uncomplicated gonorrhea, but resistance patterns limit its use.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Pneumonia, Urinary tract infections, Intra-abdominal infections, Skin infections, Meningitis
📋 Drug Information
| Generic Name(s) | Ceftriaxone + Sulbactam |
| Brand Name | Accuzon Plus 1.5gm Injection |
| Manufacturer | Elfin Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporin + Beta-lactamase inhibitor |
| Route of Administration | Intravenous (IV) infusion or injection. It must be administered by a qualified healthcare professional |
| Storage | Store the unreconstituted powder at room temperature (20-25°C). After reconstitution, the solution should be used immediately or stored as per the manufacturer's instructions, typically refrigerated (2-8°C) and used within 24 hours. Protect from light and moisture. |
| Shelf Life | The shelf life of the unreconstituted product is typically 24 months from the date of manufacture. After reconstitution, use within the time specified by the manufacturer, usually 24 hours if refrigerated. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines ceftriaxone, a third-generation cephalosporin antibiotic, with sulbactam, a beta-lactamase inhibitor. Ceftriaxone works by binding to penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting the final transpeptidation step of peptidoglycan synthesis, which leads to bacterial cell lysis and death. Sulbactam irreversibly inhibits certain beta-lactamase enzymes produced by bacteria, protecting ceftriaxone from enzymatic degradation and extending its spectrum of activity against beta-lactamase-producing organisms. This combination is bactericidal.
Mechanism Steps
💡 How to Take cefmol-sf 1gm/0.5gm injection
Strength: Each vial contains ceftriaxone sodium equivalent to 1 gram of ceftriaxone and sulbactam sodium equivalent to 0.5 gram of sulbactam. The total strength is 1.5 grams per vial.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 1.5 grams (1 gram ceftriaxone + 0.5 gram sulbactam) administered intravenously every 12 hours. For severe infections, the dose may be increased to 3 grams every 12 hours. The duration of therapy depends on the type and severity of infection and clinical response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced renal function, so dose adjustment may be necessary. Monitor renal function and adjust dose as prescribed by a clinician. |
| Renal Impairment | In patients with renal impairment (creatinine clearance < 10 mL/min), the dose of sulbactam may need to be adjusted. Ceftriaxone dose generally does not require adjustment unless both renal and hepatic impairment are present. Consult a clinician for individualized dosing. |
| Hepatic Impairment | In patients with hepatic impairment, ceftriaxone dose may need adjustment if renal function is also impaired. Monitor liver function tests. Consult a clinician for individualized dosing. |
| Maximum Daily Dose | The maximum recommended daily dose is 4 grams of ceftriaxone (not to exceed 4 grams per day) and 2 grams of sulbactam per day, but individual dosing must be determined by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefmol-sf 1gm/0.5gm injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Calcium-containing IV solutions | Major | |
| Warfarin | Major | |
| Aminoglycosides | Moderate | |
| Loop diuretics | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Minor |
🚨 Major Interactions
- Calcium-containing intravenous solutions
- Warfarin
- Aminoglycosides
⚡ Moderate Interactions
- Loop diuretics (e.g., furosemide)
- Probenecid
🍷 Alcohol Interaction
Avoid alcohol while receiving this medicine. Alcohol may worsen gastrointestinal side effects and increase the risk of certain reactions. It is best to abstain until treatment is completed and you have consulted your doctor.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe hypersensitivity to ceftriaxone, sulbactam, or other beta-lactam antibiotics","Neonates with hyperbilirubinemia","Neonates requiring calcium-containing intravenous solutions","Previous severe allergic reaction to penicillins or cephalosporins"]
⚠️ Warnings & Precautions
["Serious and occasionally fatal hypersensitivity reactions can occur. Discontinue immediately if allergic reaction occurs.","Clostridioides difficile-associated diarrhea may occur; monitor for severe diarrhea.","Use with caution in patients with renal impairment; dose adjustment may be needed.","May cause gallbladder sludge or pseudolithiasis, especially in children; monitor if abdominal symptoms occur.","Concurrent use with calcium-containing IV solutions can cause precipitation; avoid in neonates.","May interfere with certain lab tests (e.g., urine glucose tests).","Prolonged use may lead to overgrowth of non-susceptible organisms."]
🤱 Lactation Safety
Ceftriaxone and sulbactam are excreted in human breast milk in low concentrations. Caution is advised when administering to a nursing mother. Consult your doctor to weigh the benefits and potential risks to the infant.
💊 Overdose Management
Overdose with this medicine is unlikely due to its intravenous administration by healthcare professionals. In case of accidental overdose, treatment should be symptomatic and supportive. Ceftriaxone and sulbactam are not removed significantly by hemodialysis or peritoneal dialysis. Monitor vital signs and provide supportive care as needed.
⏰ Missed Dose
This medicine is administered by a healthcare professional, so missed doses are unlikely. If you miss an appointment for your dose, contact your doctor or nurse as soon as possible to reschedule. Do not attempt to self-administer a double dose.
Additional Safety Advice
This medicine must be given only by a qualified healthcare professional in a clinical setting. Do not attempt to self-administer. Inform your doctor about all your medical conditions, especially kidney or liver disease, allergies to antibiotics, or a history of colitis. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Avoid alcohol while receiving this medicine, as it may increase the risk of certain side effects. Do not use this medicine for longer than prescribed, as it can lead to antibiotic resistance and superinfections. If you experience severe diarrhea, rash, or difficulty breathing, seek immediate medical attention. Keep all follow-up appointments and lab tests as scheduled to monitor your response and check for side effects.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can affect the elimination of this medicine. Dose adjustment may be necessary. They are also at higher risk of side effects like confusion, seizures, and Clostridioides difficile infection. Close monitoring is recommended.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before starting this medicine. It is classified as Pregnancy Category B, meaning animal studies show no risk, but human data are limited. Use only if clearly needed, as determined by your healthcare provider.
🏥 Post-Surgery Considerations
This medicine is often used for surgical prophylaxis or to treat postoperative infections. It is administered intravenously in the hospital setting. Follow your surgeon's instructions regarding wound care and follow-up. Report any signs of infection like fever, redness, or discharge.
🦷 Dental Procedures
This medicine may be used prophylactically before certain dental procedures in patients at risk of infective endocarditis. However, it is not routinely used for dental infections unless they are severe. Consult your dentist and doctor for appropriate antibiotic prophylaxis.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While on this medicine, you may feel tired or weak due to the infection. Avoid strenuous exercise until you have fully recovered. Light activities like walking are generally safe, but listen to your body and rest when needed. Consult your doctor before resuming intense workouts.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital or clinic setting, so you may need to take time off work or arrange for transportation. You may experience fatigue or dizziness; avoid driving or operating heavy machinery until you know how the medicine affects you. Discuss with your employer about your treatment schedule and recovery time.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. The duration of treatment is determined by your healthcare provider based on the type and severity of infection. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor immediately; they will decide whether to stop or change the treatment.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to antibiotic resistance, superinfections such as Clostridioides difficile-associated diarrhea, and fungal infections. Prolonged therapy may also affect liver and kidney function. Regular monitoring of blood counts, liver enzymes, and renal function is recommended during extended treatment. The medicine should be used only for the prescribed duration and indication.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
For less severe infections, oral antibiotics may be used as an alternative after initial improvement with injectable therapy.
Evidence: Well-establishedDepending on the pathogen and resistance patterns, other antibiotics like piperacillin-tazobactam or meropenem may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines like the typhoid vaccine. Avoid receiving live vaccines during treatment and for a short period after. Inactivated vaccines are generally safe. Consult your doctor for personalized advice.
📦 Storage Guide
✅ DO
Store the unreconstituted powder at room temperature (20-25°C).
❌ DON'T
Do not freeze the powder.
✅ DO
After reconstitution, store the solution in the refrigerator (2-8°C) and use within 24 hours.
❌ DON'T
Do not use the reconstituted solution if it is cloudy or contains particles.
✅ DO
Keep the vial in its original carton to protect from light.
❌ DON'T
Do not store in the bathroom or near a sink.
✈️ Traveling with This Medicine
This medicine is administered in a healthcare setting, so travel is not typically applicable. If you are traveling and need to continue treatment, ensure you have a copy of your prescription and a letter from your doctor explaining the medical need. Carry the medicine in its original packaging with the pharmacy label. Check with airlines and customs about regulations for carrying injectable antibiotics. Store the medicine as directed, and keep it in a cool, dry place away from direct sunlight. If traveling across time zones, consult your doctor about adjusting the dosing schedule.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24 to 48 hours after starting treatment, but it is important to complete the full course as prescribed.
A: No, this medicine must be administered by a healthcare professional in a clinical setting.
A: Since this medicine is given by a healthcare professional, missed doses are unlikely. If you miss an appointment, contact your doctor to reschedule.
A: Avoid alcohol during treatment. No specific food restrictions are required, but maintain a healthy diet and stay hydrated.
A: Yes, allergic reactions are possible. Seek immediate medical help if you experience difficulty breathing, rash, or swelling.
🤔 Common Patient Concerns
🔄 Substitutes for cefmol-sf 1gm/0.5gm injection
View AllAlternative brands with exact same active ingredient:
-
zencef plus 1gm/0.5gm injectionHelax Healthcare Pvt. Ltd. ₹45.00 64% CHEAPER
-
ultracef-s 1gm/0.5gm injectionUltra Bio Labs ₹89.06 28.8% CHEAPER
-
deczone-s 1gm/0.5gm injectionDaksh Pharma Pvt Ltd ₹97.13 22.3% CHEAPER
-
glicef-s 1gm/0.5gm injectionNeiss Labs Pvt Ltd ₹103.13 17.5% CHEAPER
-
Traxocef-S 1gm/0.5gm InjectionMaxo Chem Ltd ₹107.81 13.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full course as prescribed by your doctor to prevent recurrence and resistance, even if symptoms improve.
🔄 Alternative Options
Generic Alternatives
- Ceftriaxone + Sulbactam injection
Brand Alternatives
- Cefton-S 1.5gm injection
- Monocef-S 1.5gm injection
- Intacef-S 1.5gm injection