Antof 100mg Tablet DT (Ofloxacin) - Complete Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Sudden severe pain, swelling, or inability to move a joint (possible tendon rupture)
- Numbness, tingling, or burning in hands or feet (peripheral neuropathy)
- Seizures, confusion, or hallucinations
- Severe allergic reaction: rash, hives, swelling of face or throat, difficulty breathing
- Severe or bloody diarrhea with fever and abdominal cramps
- Yellowing of skin or eyes, dark urine, or severe abdominal pain
- Irregular heartbeat or fainting
If experiencing severe symptoms, call emergency services immediately.
What is ceflox syrup used for?
This medicine is an antibiotic containing Ofloxacin 100mg, used to treat various bacterial infections. It works by stopping the growth of bacteria. Take it exactly as prescribed by your doctor.
- Generic Name: Ofloxacin
- Manufacturer: Maa Formulations Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 ceflox syrup के बारे में (Hindi Summary)
उपयोग: यह दवा ओफ्लोक्सासिन 100 मिलीग्राम की एक एंटीबायोटिक गोली है, जिसका उपयोग विभिन्न जीवाणु संक्रमणों के इलाज के लिए किया जाता है। यह मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, त्वचा संक्रमण और कुछ यौन संचारित संक्रमणों के इलाज में प्रभावी है। यह दवा बैक्टीरिया के डीएनए को नष्ट करके उनकी वृद्धि को रोकती है। इसे डॉक्टर के निर्देशानुसार पूरा कोर्स करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, सिरदर्द, चक्कर आना और पेट में दर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन इनमें टेंडन टूटना, तंत्रिका क्षति, दौरे और गंभीर एलर्जी प्रतिक्रियाएं शामिल हो सकती हैं। यदि आपको कोई असामान्य लक्षण दिखे तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक न छोड़ें और कोर्स पूरा करें। पर्याप्त पानी पिएं। एंटासिड, आयरन, जिंक या मैग्नीशियम सप्लीमेंट के साथ इस दवा को न लें; कम से कम 2 घंटे का अंतर रखें। धूप से बचें और सनस्क्रीन का उपयोग करें। चक्कर आने पर वाहन न चलाएं। शराब का सेवन न करें। गुर्दे या यकृत की समस्या हो तो डॉक्टर को बताएं।
💊 ceflox syrup Uses & Benefits
[{"condition":"Urinary tract infections","description":"Used to treat uncomplicated and complicated urinary tract infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Respiratory tract infections","description":"Effective against certain bacterial respiratory infections, including acute exacerbations of chronic bronchitis and pneumonia.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Prescribed for uncomplicated skin infections caused by susceptible organisms.","evidence":"Well-established"},{"condition":"Sexually transmitted infections","description":"Used in the treatment of gonorrhea and chlamydia in some cases, often in combination with other antibiotics.","evidence":"Established"},{"condition":"Prostatitis","description":"Effective against bacterial prostatitis due to good tissue penetration.","evidence":"Established"}]
Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes used off-label for severe traveler's diarrhea caused by susceptible bacteria.","evidence":"Limited"},{"condition":"Tuberculosis (second-line)","description":"Occasionally used as a second-line agent in multidrug-resistant tuberculosis regimens.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Prostatitis
📋 Drug Information
| Generic Name(s) | Ofloxacin |
| Brand Name | Auroflox 0.3% Eye Drop |
| Manufacturer | Maa Formulations Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Quinolones/ Fluroquinolones |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a fluoroquinolone antibiotic that inhibits bacterial DNA gyrase (topoisomerase II) and topoisomerase IV. These enzymes are essential for bacterial DNA replication, transcription, repair, and recombination. By binding to these enzymes, this medicine blocks the supercoiling of DNA, leading to inhibition of bacterial growth and ultimately bacterial cell death. It is bactericidal, meaning it kills bacteria directly.
Mechanism Steps
💡 How to Take ceflox syrup
Strength: Immediate-release tablet, 100 mg
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 200-400 mg every 12 hours, depending on the type and severity of infection. For uncomplicated urinary tract infections, 200 mg every 12 hours for 3-7 days is common. For more severe infections, higher doses may be used. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. Fluoroquinolones are generally not recommended for children due to risk of cartilage damage. |
| Elderly Dosage | Elderly patients may have reduced renal function and are at higher risk of tendon rupture and CNS effects. Dose adjustment may be necessary based on renal function. Use with caution. |
| Renal Impairment | In patients with renal impairment (creatinine clearance <50 mL/min), dose adjustment is required. For creatinine clearance 20-50 mL/min, the usual dose is 200 mg every 24 hours. For creatinine clearance <20 mL/min, 200 mg every 48 hours or as directed by a clinician. |
| Hepatic Impairment | No specific dose adjustment is required for hepatic impairment, as this medicine is primarily excreted unchanged by the kidneys. However, monitor liver function in patients with severe liver disease. |
| Maximum Daily Dose | The maximum recommended daily dose is 800 mg per day, divided into two doses. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of ceflox syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Antacids | Major | |
| Warfarin | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| Caffeine | Moderate | |
| Cyclosporine | Moderate | |
| Probenecid | Moderate | |
| Cimetidine | Minor | |
| Furosemide | Minor | |
| Iron supplements | Major |
🚨 Major Interactions
- Antacids, sucralfate, iron, zinc, magnesium
- Warfarin
- Theophylline
- NSAIDs (e.g., ibuprofen, naproxen)
⚡ Moderate Interactions
- Caffeine
- Cyclosporine
- Probenecid
🍷 Alcohol Interaction
Alcohol may increase the risk of central nervous system side effects such as dizziness, drowsiness, and confusion. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to ofloxacin or other fluoroquinolones","History of tendon disorders related to fluoroquinolone use","Myasthenia gravis","Children and adolescents (unless specifically indicated)","Pregnancy and lactation (unless benefit outweighs risk)"]
⚠️ Warnings & Precautions
["Tendon rupture can occur, especially in older adults, those on corticosteroids, and transplant recipients. Stop at first sign of tendon pain.","Peripheral neuropathy may be irreversible. Discontinue if symptoms occur.","Central nervous system effects including seizures, confusion, and hallucinations have been reported. Use caution in patients with CNS disorders.","May exacerbate muscle weakness in patients with myasthenia gravis. Avoid use.","Serious hypersensitivity reactions, including anaphylaxis, can occur. Discontinue immediately if reaction occurs.","Clostridioides difficile-associated diarrhea may occur. Evaluate if diarrhea develops.","Avoid excessive sun exposure due to photosensitivity risk.","May cause dizziness; avoid driving or operating machinery until effects are known.","Use with caution in patients with renal impairment; dose adjustment may be needed.","Prolonged use may lead to bacterial or fungal superinfection."]
🤱 Lactation Safety
This medicine is excreted in breast milk. Because of the potential for serious adverse reactions in nursing infants, a decision should be made whether to discontinue nursing or to discontinue the drug, taking into account the importance of the drug to the mother.
💊 Overdose Management
In case of overdose, seek immediate medical attention. Symptoms may include nausea, vomiting, dizziness, and confusion. Treatment is symptomatic and supportive. Hemodialysis does not effectively remove this medicine from the body. Contact a poison control center for guidance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early, even if you feel better. Drink plenty of water to stay hydrated. Avoid taking antacids, sucralfate, or mineral supplements containing iron, zinc, or magnesium within 2 hours before or after this medicine, as they can reduce its absorption. Avoid excessive sunlight and use sunscreen, as this medicine may increase sun sensitivity. Do not drive or operate heavy machinery if you experience dizziness. Inform your doctor if you have kidney problems, liver problems, diabetes, or a history of tendon problems. Avoid alcohol while taking this medicine. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of tendon rupture, CNS effects, and renal impairment. Dose adjustment may be needed based on renal function. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before taking this medicine. Fluoroquinolones are generally avoided during pregnancy unless clearly needed. Discuss safer alternatives.
🏥 Post-Surgery Considerations
Inform your surgeon if you are taking this medicine before surgery. It may interact with anesthetics and increase the risk of tendon problems. Your doctor may advise stopping it before surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may increase the risk of bleeding during dental procedures if taken with blood thinners. Your dentist may recommend postponing elective procedures until you complete the course.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon injury. If you experience joint pain, stop exercising and consult your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or confusion in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is advisable to take rest if you feel unwell.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience serious side effects, contact your doctor immediately.
📅 Long-Term Use Effects
Long-term use of this medicine may lead to bacterial resistance, superinfections, and rare but serious effects such as tendon damage, peripheral neuropathy, and CNS effects. It is generally prescribed for short courses. Regular monitoring of renal and liver function may be needed if used for prolonged periods.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps flush out bacteria in urinary tract infections.
Evidence: SupportiveMay help prevent antibiotic-associated diarrhea.
Evidence: Limited💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines (e.g., typhoid vaccine). Avoid vaccination with live bacterial vaccines during treatment. Consult your doctor for timing.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature and protect from light and moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage to avoid temperature extremes. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 24-48 hours, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. Taking it with food may help reduce stomach upset.
A: Avoid antacids, iron, zinc, magnesium supplements, and alcohol. Also limit caffeine and sun exposure.
🤔 Common Patient Concerns
🔄 Substitutes for ceflox syrup
View AllAlternative brands with exact same active ingredient:
-
onoff 100mg tabletSun Pharmaceutical Industries Ltd ₹10.55 80.9% CHEAPER
-
ofpil kid 100mg tablet dtPsychotropics India Ltd ₹12.50 77.4% CHEAPER
-
quilox 100mg tabletHamax Pharmaceuticals ₹13.50 75.6% CHEAPER
-
ciproj 100mg tabletJarson Pharmaceuticals ₹14.40 74% CHEAPER
-
floxip 100mg infusionAbbott ₹16.76 69.7% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the flu.
Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full course as prescribed, even if symptoms improve, to prevent bacterial resistance and recurrence. - Myth: This medicine is safe for everyone.
Fact: This medicine is not recommended for children, pregnant women, or those with certain medical conditions. Always consult a doctor.
🔄 Alternative Options
Generic Alternatives
- Ofloxacin
Brand Alternatives
- Antof 100mg Tablet DT