Cefifurt O Tablet: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, or throat, or difficulty breathing.
- Severe, persistent diarrhea or bloody stools.
- Sudden pain, swelling, or inability to move a joint, especially the Achilles tendon.
- Numbness, tingling, or burning in hands or feet.
- Seizures or convulsions.
- Yellowing of the skin or eyes, dark urine, or severe fatigue.
- Decreased urine output or swelling in the legs.
- Unusual bleeding or bruising.
- Severe headache with visual changes.
- Chest pain or irregular heartbeat.
If experiencing severe symptoms, call emergency services immediately.
What is cefifurt o tablet used for?
This medicine is a prescription antibiotic combining cefixime and ofloxacin. It treats bacterial infections like urinary tract, respiratory, and skin infections. Take it exactly as prescribed, avoid dairy and antacids within 2 hours, and do not stop early.
- Generic Name: Cefixime + Ofloxacin
- Manufacturer: Frankfurt Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cefifurt o tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक प्रिस्क्रिप्शन एंटीबायोटिक है जिसमें सेफिक्साइम और ओफ्लोक्सासिन दो सक्रिय तत्व होते हैं। यह बैक्टीरियल संक्रमण जैसे मूत्र मार्ग संक्रमण, श्वसन तंत्र संक्रमण, त्वचा संक्रमण और टाइफाइड बुखार के इलाज के लिए इस्तेमाल की जाती है। यह वायरल संक्रमण जैसे सर्दी-जुकाम के लिए प्रभावी नहीं है। इस दवा को डॉक्टर के निर्देशानुसार ही लें और कोर्स पूरा करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, पेट दर्द, सिरदर्द, चक्कर आना और त्वचा पर हल्के दाने शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें तेज एलर्जी, टेंडन टूटना, गंभीर दस्त, दौरे और तंत्रिका समस्याएं शामिल हो सकती हैं। कोई भी असामान्य लक्षण दिखने पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे पूरे पानी के साथ निगलें, चबाएं नहीं। दूध, दही, एंटासिड या मिनरल सप्लीमेंट के साथ इस दवा को न लें, कम से कम 2 घंटे का अंतर रखें। शराब न पिएं। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें। कोर्स बीच में न छोड़ें।
💊 cefifurt o tablet Uses & Benefits
[{"condition":"Complicated urinary tract infections","description":"Used when a doctor determines that a combination of cefixime and ofloxacin is needed to cover multiple possible bacteria causing the infection.","evidence":"Moderate"},{"condition":"Respiratory tract infections","description":"May be prescribed for certain bacterial bronchitis or pneumonia when a broader spectrum of coverage is required.","evidence":"Moderate"},{"condition":"Skin and soft tissue infections","description":"Can be used for bacterial skin infections such as cellulitis or abscesses when the doctor suspects a mixed bacterial cause.","evidence":"Limited"},{"condition":"Typhoid fever","description":"Sometimes used in regions where resistance patterns make this combination a reasonable choice, but only under medical supervision.","evidence":"Limited"}]
Off-label uses: [{"condition":"Gonorrhea","description":"Ofloxacin and cefixime have been used individually for gonorrhea, but the combination is not standard and should only be used if specifically advised by a specialist.","evidence":"Limited"},{"condition":"Pelvic inflammatory disease","description":"May be considered as part of a broader regimen in some settings, but not a first-line approach.","evidence":"Limited"}]
Primary treatment for: Bacterial infections
Also treats: Urinary tract infections, Respiratory tract infections, Skin infections, Typhoid fever
📋 Drug Information
| Generic Name(s) | Cefixime + Ofloxacin |
| Brand Name | Abixim O Tablet |
| Manufacturer | Frankfurt Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Antibiotic (Cephalosporin + Fluoroquinolone) |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C. Keep away from direct sunlight and moisture. Do not store in the bathroom. Keep the tablets in their original container, tightly closed. |
| Shelf Life | 24 months from the date of manufacture, or as printed on the pack. Do not use after the expiry date. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two antibiotics with different mechanisms. Cefixime, a cephalosporin, binds to penicillin-binding proteins in the bacterial cell wall, blocking the cross-linking of peptidoglycan. This weakens the cell wall and leads to bacterial death. Ofloxacin, a fluoroquinolone, inhibits DNA gyrase and topoisomerase IV, enzymes that are essential for bacterial DNA replication, repair, and transcription. By blocking these enzymes, ofloxacin prevents bacteria from multiplying and causes them to die. The combination provides a broader spectrum of activity against both gram-positive and gram-negative bacteria than either agent alone.
Mechanism Steps
💡 How to Take cefifurt o tablet
Strength: This medicine is available as an immediate-release tablet. The specific strength of cefixime and ofloxacin in this product is not provided in the available information. Check the package label or ask your pharmacist.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one tablet taken once or twice daily, depending on the type and severity of the infection. The exact dose and duration must be individualized by a qualified clinician based on the indication, your age, weight, kidney and liver function, and other medicines you are taking. Do not adjust the dose yourself. Always follow your doctor's prescription and complete the full course. |
| Pediatric Dosage | Pediatric dosing is not established from available information. This combination is generally not recommended for children under 18 years due to the ofloxacin component. Consult a pediatrician for appropriate alternatives. |
| Elderly Dosage | Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, tendon problems, and kidney effects. The dose may need to be adjusted based on kidney function. Your doctor will determine the appropriate dose for you. |
| Renal Impairment | In patients with kidney disease, the dose of this medicine may need to be reduced. Your doctor will adjust the dose based on your creatinine clearance. Regular monitoring of kidney function is advised. |
| Hepatic Impairment | In patients with liver disease, this medicine should be used with caution. Your doctor may monitor liver function. Dose adjustment may not be necessary for mild liver disease, but severe liver disease may require a different antibiotic. |
| Maximum Daily Dose | The maximum daily dose should not exceed what your doctor prescribes. Typically, the maximum adult dose is 400 mg of cefixime and 400 mg of ofloxacin per day, but this must be confirmed by your clinician. Do not exceed the prescribed dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cefifurt o tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Antacids (Al/Mg) | Major | |
| Iron/zinc supplements | Major | |
| Theophylline | Major | |
| NSAIDs | Major | |
| Corticosteroids | Major | |
| Probenecid | Moderate | |
| Oral hypoglycemics | Moderate | |
| Phenytoin | Moderate | |
| Cyclosporine | Moderate |
🚨 Major Interactions
- Warfarin
- Antacids containing aluminum or magnesium
- Sucralfate
- Iron supplements, zinc supplements, multivitamins with minerals
- Theophylline
- NSAIDs (e.g., ibuprofen, naproxen)
- Corticosteroids
⚡ Moderate Interactions
- Probenecid
- Oral hypoglycemic agents (e.g., glibenclamide)
- Phenytoin
- Cyclosporine
- Didanosine (buffered tablets)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can worsen side effects such as dizziness, drowsiness, and stomach upset. It may also increase the risk of liver problems and reduce your ability to fight the infection. It is best to wait until you have finished the course and your doctor says it is safe to drink alcohol again.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known allergy to cefixime, other cephalosporins, ofloxacin, or other fluoroquinolones.","History of tendon disorders with fluoroquinolone use.","Myasthenia gravis (ofloxacin can worsen muscle weakness).","Pregnancy and breastfeeding (unless clearly needed and advised by a doctor).","Children under 18 years of age (fluoroquinolones may affect cartilage development).","Severe kidney disease (dose adjustment needed).","History of QT interval prolongation or serious heart rhythm problems."]
⚠️ Warnings & Precautions
["Take this medicine exactly as prescribed. Do not skip doses or stop early.","Avoid taking antacids, dairy, or mineral supplements within 2 hours of this medicine.","Do not drink alcohol while taking this medicine.","Avoid driving or operating machinery if you feel dizzy or drowsy.","Tell your doctor if you have kidney or liver disease, diabetes, or heart problems.","Report any tendon pain, numbness, or tingling immediately.","If you develop severe diarrhea, contact your doctor before taking any anti-diarrheal medicine.","This medicine may make your skin more sensitive to sunlight. Use sunscreen and avoid prolonged sun exposure.","Do not use this medicine for viral infections like colds or flu.","Keep out of reach of children."]
🤱 Lactation Safety
This medicine passes into breast milk. Because of the potential risk of serious side effects in the infant, breastfeeding is not recommended while taking this medicine. If you need this medicine, your doctor may advise you to stop breastfeeding temporarily or to use a different antibiotic. Always consult your doctor before breastfeeding while on this medicine.
💊 Overdose Management
If you accidentally take more than the prescribed dose, seek medical attention immediately. Symptoms of overdose may include nausea, vomiting, dizziness, and confusion. There is no specific antidote. Treatment is supportive and may include stomach emptying if the overdose was recent. Contact your doctor or a poison control center for guidance.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. However, if it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure, consult your doctor or pharmacist.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not share it with others or save leftover tablets for later use. Swallow the tablet whole with a full glass of water; do not crush or chew it. You may take it with or without food, but taking it with a meal can reduce stomach upset. Avoid taking antacids, multivitamins, or dairy products within two hours before or after this medicine, as they can reduce absorption. Drink plenty of fluids throughout the day. Do not drink alcohol while taking this medicine, as it can increase the risk of dizziness and stomach problems. If you are pregnant, planning pregnancy, or breastfeeding, tell your doctor before starting this medicine. Inform your doctor about all other medicines you take, especially blood thinners, diabetes medicines, and steroids. Do not stop the course early even if you feel better, as this can lead to resistant infections. Keep all follow-up appointments and report any new symptoms promptly.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of side effects from this medicine, especially tendon rupture, kidney problems, dizziness, and confusion. The dose may need to be adjusted based on kidney function. Regular monitoring of kidney function and tendon health is advised. Elderly patients should take extra care to avoid falls and should report any joint pain immediately.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. Both cefixime and ofloxacin may not be safe during pregnancy. Your doctor may recommend a different antibiotic that is safer for pregnancy. Use effective contraception while taking this medicine if you are of childbearing age and not planning pregnancy.
🏥 Post-Surgery Considerations
If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may interact with other medications used during surgery. In some cases, your doctor may advise you to stop this medicine before surgery. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may interact with other medications or affect healing. Your dentist may consult with your doctor to decide whether to continue or temporarily stop the medicine.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, avoid strenuous exercise or high-impact activities that could strain your tendons, especially if you are over 60 or have had tendon problems before. If you experience any joint pain, stop exercising and consult your doctor. Light activities like walking are generally safe if you feel well.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, drowsiness, or headache in some people. Avoid driving or operating heavy machinery until you know how it affects you. If your work involves fine motor skills or alertness, take extra care. Most people can continue their normal daily activities, but listen to your body and rest when needed.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can allow the infection to return and may lead to antibiotic resistance. If you experience a serious side effect such as a severe allergic reaction, tendon pain, or severe diarrhea, stop the medicine and seek medical help immediately. Your doctor will advise you on whether to stop or switch to another antibiotic.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless specifically directed by a doctor. Prolonged use can lead to antibiotic resistance, fungal overgrowth, and rare but serious effects such as tendon damage, nerve damage, and liver or kidney problems. If you need long-term therapy, your doctor will monitor your kidney and liver function, blood counts, and any signs of tendon or nerve issues. Always discuss the risks and benefits with your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Using a narrower antibiotic that specifically targets the identified bacteria can be safer and equally effective.
Evidence: Well-establishedMay help prevent antibiotic-associated diarrhea, but should be taken at least 2 hours apart from the antibiotic.
Evidence: ModerateSupports the body's natural healing, especially for urinary tract infections.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines such as the typhoid vaccine. If you are scheduled to receive any vaccine, inform your doctor that you are taking this medicine. Generally, antibiotics do not interfere with viral vaccines, but it is best to discuss timing with your healthcare provider.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. Store at room temperature and protect from direct sunlight. If crossing time zones, continue taking the medicine at the same intervals as prescribed; you may need to adjust the timing gradually. Check local customs regulations for carrying prescription medicines. Always carry enough for your entire trip and a little extra in case of delays.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 1-2 days, but the full effect may take 2-3 days. Complete the full course as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal. Avoid dairy and antacids within 2 hours.
A: Take it as soon as you remember if less than half the interval has passed. Otherwise, skip it and continue your regular schedule. Do not double dose.
A: This medicine is not recommended during pregnancy unless clearly needed. Consult your doctor for safer alternatives.
A: Avoid alcohol while taking this medicine as it can increase dizziness, drowsiness, and stomach upset.
🤔 Common Patient Concerns
🔄 Substitutes for cefifurt o tablet
View AllAlternative brands with exact same active ingredient:
-
taxone of tabletMapra Laboratories Pvt Ltd ₹96.56 4.6% CHEAPER
-
cefiyug o tabletYug Pharmaceuticals ₹177.19 75% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: Antibiotics can cure viral infections like the common cold.
Fact: This medicine only works against bacteria. It is not effective for viral infections. - Myth: You can stop taking antibiotics once you feel better.
Fact: You must complete the full course to prevent the infection from returning and to avoid antibiotic resistance. - Myth: It is safe to take antibiotics with alcohol.
Fact: Alcohol can worsen side effects and should be avoided while taking this medicine. - Myth: Antibiotics can be shared with family members.
Fact: Never share antibiotics. They are prescribed for a specific infection and person.
🔄 Alternative Options
Generic Alternatives
- Cefixime + Ofloxacin (generic versions may be available)
Brand Alternatives
- Cefifurt O Tablet