cefifurt cv tablet - Cefixime (NA) + Clavulanic Acid (NA) medicine

Ceme CV Tablet: Complete Medicine Guide

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🏭 Frankfurt Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 25, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Severe diarrhea with fever

If experiencing severe symptoms, call emergency services immediately.

What is cefifurt cv tablet used for?

This medicine is a prescription antibiotic combining cefixime and clavulanic acid. It treats bacterial infections of the respiratory tract, urinary tract, ear, nose, throat, and skin. It works by killing bacteria and is taken orally with food. Complete the full course as prescribed.

  • Generic Name: Cefixime + Clavulanic Acid
  • Manufacturer: Frankfurt Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 cefifurt cv tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एक प्रिस्क्रिप्शन एंटीबायोटिक है जिसमें सेफिक्साइम और क्लैवुलैनिक एसिड होता है। यह श्वसन तंत्र, मूत्र मार्ग, कान, नाक, गले और त्वचा के बैक्टीरियल संक्रमणों के इलाज के लिए उपयोग की जाती है। यह बैक्टीरिया को मारकर काम करती है। इसे भोजन के साथ मुँह से लिया जाता है। डॉक्टर के बताए अनुसार पूरा कोर्स पूरा करें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में दस्त, जी मिचलाना, पेट दर्द और अपच शामिल हैं। कुछ लोगों को सिरदर्द, चक्कर आना या हल्के दाने हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें गंभीर एलर्जी, गंभीर दस्त, यकृत या गुर्दे की समस्या शामिल हो सकती है। कोई भी असामान्य लक्षण होने पर तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। खुराक न छोड़ें और कोर्स बीच में न रोकें। इसे भोजन के साथ लें ताकि पेट की परेशानी कम हो। खूब पानी पिएं। इस दवा के साथ शराब न पिएं। अगर आपको गुर्दे या यकृत की बीमारी है या पेनिसिलिन से एलर्जी है तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 cefifurt cv tablet Uses & Benefits

[{"condition":"Respiratory tract infections","description":"Used to treat community-acquired pneumonia, acute bronchitis, and acute exacerbations of chronic bronchitis caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Urinary tract infections","description":"Effective against uncomplicated and complicated urinary tract infections caused by susceptible Gram-negative bacteria.","evidence":"Well-established"},{"condition":"Ear, nose, and throat infections","description":"Used for otitis media, sinusitis, pharyngitis, and tonsillitis when caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats uncomplicated skin infections such as cellulitis, abscesses, and wound infections caused by susceptible organisms.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Gonorrhea","description":"Sometimes used as an alternative treatment for uncomplicated gonorrhea, but resistance patterns vary and other agents are preferred.","evidence":"Limited"},{"condition":"Typhoid fever","description":"May be used in some regions for typhoid fever, but susceptibility testing is essential due to emerging resistance.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Respiratory tract infections, Urinary tract infections, Ear, nose, and throat infections, Skin infections

📋 Drug Information

Generic Name(s)Cefixime + Clavulanic Acid
Brand NameAbixim CV 200mg/125mg Tablet
ManufacturerFrankfurt Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassANTI INFECTIVES
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Protect from light and moisture. Keep in the original container.
Shelf LifeThe shelf life of this medicine is typically 24 months from the date of manufacture. Check the expiry date on the packaging before use.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce stomach upset.
2
Complete the full prescribed course even if you feel better.
3
Stay well hydrated throughout the day.
4
Avoid alcohol while taking this medicine.
5
Do not share this medicine with others.
6
Report any unusual bleeding, bruising, or severe diarrhea immediately.
7
Inform your doctor if you are allergic to penicillin or cephalosporins.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with cough
This medicine may be prescribed for respiratory infections.
Likely Use
✅
Burning urination
This medicine may be prescribed for urinary tract infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCefixime is absorbed from the gastrointestinal tract after oral administration. Clavulanic acid is also absorbed orally. Food may slightly delay absorption but does not significantly reduce the overall extent. Specific bioavailability data for this combination product are not established from the available information.
DistributionCefixime distributes widely into body tissues and fluids, including the respiratory tract, urine, and bile. Clavulanic acid also distributes into various tissues. Protein binding of cefixime is moderate, while clavulanic acid is approximately 25% bound. Specific distribution data for this combination are not established from the available information.
Protein BindingCefixime is approximately 65% bound to plasma proteins. Clavulanic acid is about 25% bound. These values are for the individual components and may not reflect the combination product exactly.
MetabolismCefixime is not significantly metabolized and is excreted largely unchanged. Clavulanic acid undergoes extensive metabolism, primarily in the liver. Specific metabolic data for this combination are not established from the available information.
Half-LifeThe elimination half-life of cefixime is approximately 3 to 4 hours in healthy adults. The half-life of clavulanic acid is about 1 hour. These values may be prolonged in patients with renal impairment.
ExcretionCefixime is primarily excreted unchanged in the urine. Clavulanic acid is excreted in urine and feces. Renal impairment can affect the elimination of both components.
BioavailabilityThe oral bioavailability of cefixime is approximately 40% to 50%. The bioavailability of clavulanic acid is about 60% to 70%. Specific bioavailability data for this combination product are not established from the available information.
Onset of ActionThe onset of action for this medicine is not established from the available information. Clinical improvement in infections typically occurs within 24 to 48 hours after starting therapy.
Peak Plasma TimePeak plasma concentrations of cefixime are reached approximately 2 to 4 hours after oral administration. Clavulanic acid peaks at about 1 to 2 hours. These times may vary with food intake.
Duration of ActionThe duration of action for this medicine is not established from the available information. The antibacterial effect persists as long as effective concentrations are maintained, typically requiring dosing every 12 hours.

How It Works

This medicine combines cefixime, a third-generation cephalosporin antibiotic, with clavulanic acid, a beta-lactamase inhibitor. Cefixime works by binding to penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting cell wall synthesis and leading to bacterial death. Clavulanic acid irreversibly inhibits certain beta-lactamase enzymes produced by bacteria, protecting cefixime from degradation and extending its spectrum of activity against beta-lactamase-producing strains.

Mechanism Steps

1
Cefixime binds to PBPs: Cefixime binds to specific penicillin-binding proteins on the bacterial cell membrane, disrupting cell wall synthesis.
2
Clavulanic acid inhibits beta-lactamases: Clavulanic acid binds irreversibly to beta-lactamase enzymes, preventing them from breaking down cefixime.
3
Bacterial cell lysis: Inhibition of cell wall synthesis leads to bacterial cell lysis and death, especially in actively dividing bacteria.

💡 How to Take cefifurt cv tablet

Strength: This medicine is available as an immediate-release oral tablet. The strength is not specified in the available information.

1Take this medicine by mouth with a full glass of water.
2Take it with food to reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Take at evenly spaced intervals as prescribed.
5Complete the full course even if you feel better.

Dosage Information

Adult DosageThe usual adult dose of this medicine is one tablet taken orally every 12 hours, but the exact dose and duration depend on the type and severity of the infection, your kidney function, and other factors. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not self-adjust the dose.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children.
Elderly DosageElderly patients may have reduced kidney function and may require dose adjustment. Your doctor will determine the appropriate dose based on your renal function.
Renal ImpairmentIn patients with renal impairment, dose adjustment is required. For creatinine clearance between 20 and 40 mL/min, the dose may be reduced to once daily or half the usual dose. For creatinine clearance below 20 mL/min, the dose may need further reduction. Consult your doctor for specific guidance.
Hepatic ImpairmentNo specific dose adjustment is established for hepatic impairment, but use with caution and monitor liver function.
Maximum Daily DoseThe maximum recommended daily dose is not established from the available information. Follow your doctor's prescription.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
May increase stomach upset and liver effects.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of cefifurt cv tablet

✅ Common Side Effects

Diarrhea (Common (5-10%))
Usually resolves on its own. Stay hydrated. Consult doctor if persistent or severe.
Nausea (Common (5-10%))
Take with food. Consult doctor if it interferes with eating.
Stomach pain (Common (5-10%))
Take with food. Consult doctor if severe or persistent.
Headache (Uncommon (1-5%))
Usually resolves. Consult doctor if severe or persistent.
Rash (Uncommon (1-5%))
Consult doctor if rash develops, as it may indicate allergy.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Clostridium difficile-associated diarrhea (Rare (<0.1%))
Seek immediate medical attention if you develop severe, persistent diarrhea, abdominal pain, or fever.
Liver toxicity (Rare (<0.1%))
Seek medical attention if you notice yellowing of skin or eyes, dark urine, or severe abdominal pain.
Kidney toxicity (Rare (<0.1%))
Seek medical attention if you notice decreased urine output, swelling, or fatigue.
Blood disorders (e.g., neutropenia, thrombocytopenia) (Rare (<0.1%))
Seek medical attention if you experience unusual bleeding, bruising, or signs of infection.

⚠️ Rare Side Effects

Seizures
Seek immediate medical attention.
Hemolytic anemia
Seek immediate medical attention if you experience fatigue, pale skin, or shortness of breath.
Interstitial nephritis
Seek medical attention if you experience fever, rash, and decreased urine output.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Methotrexate Major
Probenecid Moderate
Oral contraceptives Moderate
Loop diuretics Moderate
Antacids Minor
Iron supplements Minor

🚨 Major Interactions

  • Warfarin
  • Methotrexate
  • Probenecid

⚡ Moderate Interactions

  • Oral contraceptives
  • Loop diuretics

🍷 Alcohol Interaction

Alcohol may increase the risk of gastrointestinal side effects such as nausea and stomach pain. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known allergy to cefixime, clavulanic acid, or any other cephalosporin or penicillin antibiotics.","History of severe allergic reaction to beta-lactam antibiotics.","Use in patients with a history of Clostridium difficile-associated diarrhea.","Not recommended for patients with severe renal impairment without dose adjustment."]

⚠️ Warnings & Precautions

["Before starting this medicine, inform your doctor if you are allergic to penicillin or cephalosporins.","Use with caution in patients with kidney disease; dose adjustment may be needed.","Use with caution in patients with liver disease; monitor liver function.","Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Do not use this medicine to treat viral infections.","Complete the full course as prescribed, even if you feel better.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Cefixime and clavulanic acid are excreted in breast milk in small amounts. This medicine is generally considered compatible with breastfeeding, but consult your doctor to weigh the benefits and risks.

💊 Overdose Management

Overdose of this medicine may cause nausea, vomiting, stomach pain, and diarrhea. In severe cases, it may lead to seizures or kidney problems. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered in severe cases, but its effectiveness is not well established.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not skip doses or stop early. Take it with food to reduce stomach upset. Drink plenty of water. Avoid alcohol while taking this medicine. Inform your doctor if you have kidney or liver disease, or if you are allergic to penicillin or cephalosporins. Do not share this medicine with others. Keep out of reach of children. Store in a cool, dry place away from direct sunlight.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may have reduced kidney function and may require dose adjustment. They may also be more susceptible to side effects. Regular monitoring is advised.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe when prescribed, but your doctor will weigh the benefits and risks.

🏥 Post-Surgery Considerations

This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine. It may interact with other medications used during dental procedures. It is not typically used for dental infections unless prescribed.

💚 Lifestyle Tips for Better Results

🏃
Get plenty of rest to help your body fight the infection.
🥗
Drink plenty of fluids to stay hydrated.
😴
Eat a balanced diet rich in fruits and vegetables.
💧
Practice good hygiene to prevent spread of infection.
🧘
Avoid close contact with others while infectious.
🌞
Complete the full course of antibiotics as prescribed.

🏋️ Exercise Considerations

If you feel dizzy or weak while taking this medicine, avoid strenuous exercise. Light activity is fine if you feel up to it. Listen to your body and rest when needed.

🥗 Diet Recommendations

Stay well hydrated
Include probiotic-rich foods like yogurt to help prevent diarrhea
Avoid alcohol
Eat light, easily digestible meals if you have stomach upset

💼 Impact on Daily Work & Life

This medicine may cause dizziness in some people. Avoid driving or operating heavy machinery until you know how it affects you. You can usually continue your normal daily activities if you feel well enough.

🛑 When to Stop This Medicine

Do not stop taking this medicine before completing the full prescribed course, even if you feel better. Stopping early can lead to recurrence of infection and antibiotic resistance. If you experience severe side effects, contact your doctor before stopping.

📅 Long-Term Use Effects

Long-term use of this medicine may lead to antibiotic resistance and superinfections. It is not intended for prolonged use unless prescribed by a doctor for a specific chronic infection. Regular monitoring of kidney and liver function may be needed if used for extended periods.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Probiotics

May help prevent antibiotic-associated diarrhea.

Evidence: Limited
Symptomatic treatment

Rest, fluids, and pain relievers for symptom relief while the antibiotic works.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine may reduce the effectiveness of live bacterial vaccines such as typhoid vaccine. Consult your doctor about vaccination timing.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from extreme heat or moisture. If crossing time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with a urinary tract infection
She was prescribed this medicine for a urinary tract infection. She took it with food as directed and completed the 7-day course. Her symptoms improved within 3 days, and she felt completely better by the end of the course. She experienced mild nausea initially, which resolved after taking it with meals.
💡 Lesson: Taking the medicine with food reduces stomach upset, and completing the full course prevents recurrence.
👤 A 50-year-old man with a respiratory tract infection
He started this medicine for bronchitis. He noticed improvement in his cough and fever within 48 hours. He was advised to avoid alcohol and to rest. He completed the 10-day course and recovered fully without any serious side effects.
💡 Lesson: Adhering to the prescribed duration and following lifestyle advice leads to successful treatment.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 24 to 48 hours, but you must complete the full prescribed course.

Q: Can I take it with food?

A: Yes, take it with food to reduce stomach upset.

Q: What if I miss a dose?

A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose. Do not double dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for cefifurt cv tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Antibiotics can cure viral infections like the common cold.
    Fact: This medicine is effective only against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking antibiotics once you feel better.
    Fact: You must complete the full prescribed course to prevent recurrence and resistance.
  • Myth: Antibiotics can be shared with others.
    Fact: Never share antibiotics. They are prescribed for a specific infection and person.

🔄 Alternative Options

Generic Alternatives

  • Cefixime + Clavulanic Acid tablets

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Cefixime + Clavulanic Acid","class":"Third-generation cephalosporin + beta-lactamase inhibitor","route":"Oral","common_use":"Respiratory, urinary, ENT, skin infections"},{"medicine":"Amoxicillin + Clavulanic Acid","composition":"Amoxicillin + Clavulanic Acid","class":"Aminopenicillin + beta-lactamase inhibitor","route":"Oral","common_use":"Respiratory, urinary, skin infections"}]

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