cefaone 250mg injection - Uses, Price, Side Effects & Substitutes
What is cefaone 250mg injection used for?
Avucef 500mg Injection (Cefoperazone) is used to treat ANTI INFECTIVES. It contains Cefoperazone (250mg), which Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins. Always consult your doctor before use. Take as prescribed.
- Generic Name: Cefoperazone
- Manufacturer: Mefro Pharmaceuticals Pvt Ltd
- Form: Allopathy
- Pregnancy Category: B
- Prescription Required: Yes
๐ cefaone 250mg injection Uses & Benefits
Treatment of respiratory tract infections, urinary tract infections, skin and soft tissue infections, septicemia, intra-abdominal infections, gynecological infections
Off-label uses: Bacterial meningitis, Lyme disease, Typhoid fever
๐ Drug Information
| Generic Name(s) | Cefoperazone |
| Brand Name | Avucef 500mg Injection |
| Manufacturer | Mefro Pharmaceuticals Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Intravenous (IV) or intramuscular (IM) |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Inhibits bacterial cell wall synthesis by binding to penicillin-binding proteins (PBPs)
Mechanism Steps
๐ก How to Take cefaone 250mg injection
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of cefaone 250mg injection
โ Common Side Effects
- Diarrhea
- Nausea
- Vomiting
- Rash
- Injection site reactions
๐จ Serious Side Effects
- Pseudomembranous colitis
- Anaphylaxis
- Stevens-Johnson syndrome
- Bleeding tendencies
- Seizures
โ ๏ธ Rare Side Effects
- Hemolytic anemia
- Agranulocytosis
- Interstitial nephritis
- Hepatitis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Alcohol | Major | Disulfiram-like reaction |
| Warfarin | Major | Increased bleeding risk |
| Heparin | Major | Increased bleeding risk |
| Oral anticoagulants | Major | Increased bleeding risk |
| Aminoglycosides | Moderate | Increased nephrotoxicity risk |
| Loop diuretics | Moderate | Increased nephrotoxicity risk |
| Probenecid | Moderate | Decreased renal excretion of cefoperazone |
| Tetracyclines | Minor | Possible antagonism |
| Chloramphenicol | Minor | Possible antagonism |
๐จ Major Interactions
- Alcohol
- Warfarin
- Heparin
- Oral anticoagulants
โก Moderate Interactions
- Aminoglycosides
- Loop diuretics
- Probenecid
โน๏ธ Minor Interactions
- Tetracyclines
- Chloramphenicol
๐ท Alcohol Interaction
Disulfiram-like reaction (flushing, headache, nausea, vomiting, tachycardia)
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to cefoperazone or other cephalosporins, severe penicillin allergy
๐ Monitoring Parameters
Renal function, hepatic function, CBC, signs of bleeding, superinfection
๐คฑ Lactation Safety
Excreted in breast milk in small amounts; use with caution
๐ Overdose Management
Supportive care; hemodialysis may enhance elimination
โฐ Missed Dose
Administer as soon as remembered; do not double dose
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for cefaone 250mg injection
View AllAlternative brands with exact same active ingredient (Cefoperazone (250mg)):
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Medical Note: Always consult your doctor before switching medications.