Alphadopa L Tablet (Labetalol 100 mg): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Severe dizziness or fainting
- Very slow heart rate (below 50 beats per minute)
- Difficulty breathing or wheezing
- Chest pain or palpitations
- Yellowing of skin or eyes
- Swelling of face, lips, or throat
- Sudden weight gain or swelling in legs
If experiencing severe symptoms, call emergency services immediately.
What is cebalol 100mg tablet used for?
This medicine is an oral tablet containing Labetalol 100 mg, used to treat high blood pressure. It works by blocking alpha and beta receptors, which relaxes blood vessels and slows the heart rate. It is also used in pregnancy-related hypertension under medical supervision.
- Generic Name: Labetalol
- Manufacturer: Health Biotech Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cebalol 100mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मुख्य रूप से उच्च रक्तचाप (हाई ब्लड प्रेशर) के इलाज के लिए इस्तेमाल की जाती है। यह रक्त वाहिकाओं को आराम देकर और हृदय की गति को धीमा करके रक्तचाप को कम करती है। गर्भावस्था के दौरान उच्च रक्तचाप के प्रबंधन में भी यह दवा डॉक्टर की सलाह पर दी जा सकती है। यह दवा दिल के दौरे और स्ट्रोक के खतरे को कम करने में मदद करती है। इसे डॉक्टर के बताए अनुसार ही लें, अपने आप बंद न करें।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में चक्कर आना, थकान, सिरदर्द, जी मिचलाना और नाक बंद होना शामिल हैं। कुछ लोगों को त्वचा पर झुनझुनी महसूस हो सकती है। गंभीर दुष्प्रभाव कम होते हैं, लेकिन दिल की धड़कन बहुत धीमी होना, बेहोशी के साथ बहुत कम रक्तचाप, सांस लेने में कठिनाई, या पीलिया जैसे लक्षण दिखें तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें, आमतौर पर खाने के साथ या बिना खाने के, लेकिन हर दिन एक ही समय पर लें। इसे अचानक बंद न करें, क्योंकि इससे रक्तचाप बढ़ सकता है या दिल की समस्या हो सकती है। जब तक आपको पता न चले कि यह दवा आप पर कैसा असर करती है, तब तक वाहन चलाने या मशीनरी चलाने से बचें। गर्भावस्था, स्तनपान या गर्भधारण की योजना के बारे में अपने डॉक्टर को बताएं। शराब का सेवन न करें। नियमित जांच के लिए डॉक्टर के पास जाएं।
💊 cebalol 100mg tablet Uses & Benefits
[{"condition":"Hypertension","description":"Lowers high blood pressure by reducing peripheral vascular resistance and heart rate, thereby decreasing the risk of stroke, heart attack, and kidney damage.","evidence":"Well-established"},{"condition":"Hypertension in pregnancy","description":"Used to manage high blood pressure during pregnancy when deemed appropriate by an obstetrician, as it is considered relatively safe compared to some other antihypertensives.","evidence":"Well-established"},{"condition":"Hypertensive emergencies","description":"May be used in certain acute severe hypertension settings under close medical supervision, though intravenous forms are more commonly used for emergencies.","evidence":"Established"}]
Off-label uses: [{"condition":"Pheochromocytoma","description":"Occasionally used to control blood pressure in patients with pheochromocytoma, but only after alpha-blockade is established to avoid a paradoxical hypertensive crisis.","evidence":"Limited"},{"condition":"Clonidine withdrawal hypertension","description":"Sometimes used to manage rebound hypertension after sudden clonidine withdrawal, but this is not a standard first-line approach.","evidence":"Limited"}]
Primary treatment for: Hypertension
Also treats: Hypertension in pregnancy, Hypertensive emergencies
📋 Drug Information
| Generic Name(s) | Labetalol |
| Brand Name | Alphadopa L |
| Manufacturer | Health Biotech Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | CARDIAC |
| Action Class | Alpha & beta blocker |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Protect from moisture and direct sunlight. Keep in the original container. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | The World Health Organization recommends labetalol as one of the first-line medicines for managing severe hypertension in pregnancy. It is included in the WHO Model List of Essential Medicines. |
| ICMR Guideline | The Indian Council of Medical Research recognizes labetalol as a suitable option for managing hypertension in pregnancy and for certain hypertensive emergencies, as per national guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by blocking both alpha-1 adrenergic receptors and beta-adrenergic receptors. Blocking alpha-1 receptors on blood vessels causes vasodilation, which lowers blood pressure. Blocking beta receptors reduces heart rate, decreases the force of heart contractions, and suppresses renin release from the kidneys. The combined effect reduces blood pressure both at rest and during exercise, while maintaining cardiac output better than pure beta-blockers in some patients.
Mechanism Steps
💡 How to Take cebalol 100mg tablet
Strength: Labetalol 100 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual starting dose for hypertension is 100 mg taken orally twice daily, with or without food. Your doctor may increase the dose gradually based on your blood pressure response, typically at intervals of 2 to 3 days. The maintenance dose ranges from 200 mg to 400 mg twice daily. For severe hypertension, higher doses may be used under close supervision. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function, and response to therapy. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and titrate slowly. Monitor blood pressure and heart rate closely. |
| Renal Impairment | No specific dose adjustment is usually required for mild to moderate renal impairment. However, use with caution in severe renal impairment and monitor kidney function. |
| Hepatic Impairment | In patients with liver disease, the dose may need to be reduced because this medicine is metabolized in the liver. Monitor liver function and adjust dose as needed. |
| Maximum Daily Dose | The maximum recommended daily dose is 2400 mg, but doses above 1200 mg per day are rarely used. Dose must be individualized by a qualified clinician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cebalol 100mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Verapamil | Major | |
| Clonidine | Major | |
| MAOIs | Major | |
| NSAIDs | Moderate | |
| Salbutamol | Moderate | |
| Insulin | Moderate | |
| Cimetidine | Moderate | |
| Antacids | Minor | |
| Grapefruit juice | Minor |
🚨 Major Interactions
- Verapamil or diltiazem
- Clonidine
- Monoamine oxidase inhibitors (MAOIs)
⚡ Moderate Interactions
- Nonsteroidal anti-inflammatory drugs (NSAIDs)
- Beta-2 agonists (e.g., salbutamol)
- Insulin and oral antidiabetics
- Cimetidine
🍷 Alcohol Interaction
Alcohol can increase the blood pressure-lowering effect of this medicine and may cause excessive dizziness, lightheadedness, and fainting. It is best to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Severe bradycardia","Heart block greater than first degree","Cardiogenic shock","Severe heart failure","Asthma or severe chronic obstructive pulmonary disease","Severe liver disease","Known hypersensitivity to labetalol"]
⚠️ Warnings & Precautions
["Do not stop this medicine suddenly, as it can cause rebound hypertension, chest pain, or heart attack.","Use with caution in patients with asthma or other respiratory diseases.","May mask symptoms of hypoglycemia in diabetic patients.","Use with caution in patients with liver or kidney disease.","May cause dizziness; avoid driving or operating machinery until you know how it affects you.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding.","Avoid alcohol while taking this medicine."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered safe for breastfeeding mothers, but you should consult your doctor to weigh the benefits and risks. Monitor the baby for any unusual symptoms such as excessive sleepiness or poor feeding.
💊 Overdose Management
Overdose can cause severe low blood pressure, very slow heart rate, heart failure, and bronchospasm. Seek emergency medical attention immediately. Treatment is supportive and may include intravenous fluids, atropine for bradycardia, vasopressors for hypotension, and beta-agonists for bronchospasm. Gastric lavage may be considered if the overdose is recent.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, usually with or without food, but try to take it at the same time each day. Do not stop this medicine suddenly on your own, because abrupt withdrawal can cause chest pain, rapid heartbeat, or a dangerous rise in blood pressure. Avoid driving or operating heavy machinery until you know how this medicine affects you, as it can cause dizziness or tiredness. Tell your doctor if you are pregnant, planning to become pregnant, or breastfeeding, because this medicine may affect the baby. Avoid alcohol while taking this medicine, as it can increase dizziness and low blood pressure. Keep all follow-up appointments so your doctor can check your blood pressure, heart rate, and liver function. Store this medicine at room temperature, away from moisture and direct sunlight, and keep it out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the blood pressure-lowering effects of this medicine. Start with a lower dose and titrate slowly. Monitor blood pressure and heart rate closely to avoid excessive hypotension and falls.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss your blood pressure medicines with your doctor. This medicine is sometimes used in pregnancy, but your doctor will determine the safest option for you and your baby. Do not stop or change medicines without medical advice.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine before any surgery. It may interact with anesthetic agents and affect blood pressure and heart rate during surgery. Your doctor may adjust the dose or temporarily switch to another medicine.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. It may cause dry mouth or interact with local anesthetics containing epinephrine, potentially affecting blood pressure and heart rate. Your dentist may take precautions.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
This medicine can cause dizziness or tiredness, especially when you first start taking it or when the dose is increased. Avoid strenuous exercise or heavy lifting until you know how this medicine affects you. If you feel dizzy during exercise, stop and rest. Consult your doctor before starting any new exercise program.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or tiredness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is usually safe to continue your normal work routine, but inform your employer if your job involves operating heavy machinery. Take breaks and stay hydrated if you feel lightheaded.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. If you experience serious side effects such as severe dizziness, fainting, difficulty breathing, or signs of liver injury, contact your doctor immediately. Your doctor may adjust the dose or switch you to a different medicine. Abrupt withdrawal can cause rebound hypertension, chest pain, or heart attack.
📅 Long-Term Use Effects
Long-term use of this medicine is generally safe when monitored appropriately. Regular check-ups should include blood pressure, heart rate, liver function, and kidney function tests. Some patients may develop tolerance or need dose adjustments over time. It is important to continue lifestyle modifications such as a healthy diet and exercise to maintain blood pressure control.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Diet, exercise, weight loss, and stress reduction can help lower blood pressure and complement medicine.
Evidence: Well-establishedACE inhibitors, ARBs, calcium channel blockers, and diuretics are alternatives depending on your condition.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, always inform your healthcare provider about all medicines you are taking before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or moisture. If crossing time zones, adjust dosing times gradually in consultation with your doctor. Check local customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts lowering blood pressure within 20 minutes to 2 hours after a dose, but it may take a few days to weeks to achieve full effect. Your doctor will adjust the dose based on your response.
A: This medicine is sometimes used in pregnancy for high blood pressure, but only under the supervision of an obstetrician. Do not start or stop any medicine during pregnancy without consulting your doctor.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: No, do not stop this medicine suddenly even if your blood pressure is normal. Stopping abruptly can cause rebound hypertension, chest pain, or heart attack. Consult your doctor before making any changes.
🤔 Common Patient Concerns
🔄 Substitutes for cebalol 100mg tablet
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Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be stopped once blood pressure is normal.
Fact: High blood pressure often has no symptoms, and stopping this medicine suddenly can cause dangerous rebound hypertension. Always consult your doctor before stopping. - Myth: This medicine is safe for everyone with high blood pressure.
Fact: It is not suitable for people with asthma, certain heart conditions, or severe liver disease. Your doctor will decide if it is right for you. - Myth: This medicine can be taken without monitoring.
Fact: Regular monitoring of blood pressure, heart rate, and liver function is important while taking this medicine.
🔄 Alternative Options
Generic Alternatives
- Labetalol 100 mg tablet
Brand Alternatives
- Alphadopa L Tablet