ccfs tablet - Cetirizine (10mg) + Paracetamol (500mg) medicine

Asicold Plus 10mg/500mg/30mg Tablet: Complete Medicine Guide

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🏭 Shreshtha Formulations 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 25, 2026
⚠️ Hepatotoxicity Risk 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for symptomatic relief of allergic rhinitis and common cold.
Reviewed by
SaathiMed Expert Panel | Sep 25, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Yellowing of skin or eyes (jaundice)
  • Severe abdominal pain or vomiting blood
  • Difficulty breathing or swelling of face, lips, or throat
  • Unusual bleeding or bruising
  • Severe drowsiness or confusion
  • Decreased urine output
  • Persistent fever for more than 3 days

If experiencing severe symptoms, call emergency services immediately.

What is ccfs tablet used for?

This medicine is a combination of Cetirizine (an antihistamine) and Paracetamol (a pain reliever and fever reducer). It is used to treat symptoms of allergies and the common cold, such as sneezing, runny nose, and mild fever. It should be taken as prescribed by a doctor and should not be used for more than 7 days without medical advice.

  • Generic Name: Cetirizine + Paracetamol
  • Manufacturer: Shreshtha Formulations
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 ccfs tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एलर्जी और सर्दी-जुकाम के लक्षणों जैसे छींक आना, नाक बहना, आंखों में खुजली और पानी आना, हल्का बुखार और शरीर दर्द में राहत देने के लिए इस्तेमाल की जाती है। इसमें सेटिरिज़िन और पैरासिटामोल दो दवाएं होती हैं। सेटिरिज़िन एलर्जी को कम करती है और पैरासिटामोल बुखार और दर्द को कम करती है। यह दवा डॉक्टर की सलाह पर ही लेनी चाहिए।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में नींद आना, मुंह सूखना, थकान, जी मिचलाना और पेट में हल्का दर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन अगर आपको त्वचा पर चकत्ते, सूजन, सांस लेने में कठिनाई, या पीलिया जैसे लक्षण दिखें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य समस्याओं और दवाओं के बारे में बताएं। शराब का सेवन न करें क्योंकि इससे लीवर को नुकसान हो सकता है और नींद बढ़ सकती है। इस दवा को लेने के बाद गाड़ी चलाने या मशीन चलाने से बचें। निर्धारित खुराक से अधिक न लें। 7 दिनों से अधिक इसका उपयोग बिना डॉक्टर की सलाह के न करें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 ccfs tablet Uses & Benefits

[{"condition":"Allergic rhinitis","description":"Relieves sneezing, runny nose, itchy and watery eyes, and nasal congestion associated with seasonal or perennial allergies.","evidence":"Well-established"},{"condition":"Common cold","description":"Provides symptomatic relief from runny nose, sneezing, and mild fever or body ache associated with the common cold.","evidence":"Well-established"},{"condition":"Allergic skin conditions","description":"Helps reduce itching and hives (urticaria) due to allergic reactions.","evidence":"Well-established"},{"condition":"Fever","description":"Paracetamol component helps reduce mild to moderate fever.","evidence":"Well-established"},{"condition":"Mild to moderate pain","description":"Paracetamol component provides relief from mild to moderate pain such as headache, body ache, or toothache.","evidence":"Well-established"}]

Off-label uses: [{"condition":"Insomnia due to allergic symptoms","description":"Sometimes used off-label for its sedative effect to help sleep in patients with allergic symptoms, but this is not a recommended use.","evidence":"Limited"}]

Primary treatment for: Allergic rhinitis

Also treats: Common cold, Urticaria, Fever, Mild to moderate pain

📋 Drug Information

Generic Name(s)Cetirizine + Paracetamol
Brand NameAlerid Cold Tablet
ManufacturerShreshtha Formulations
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Analgesic/Antipyretic
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce the risk of stomach upset.
2
Avoid driving or operating heavy machinery after taking this medicine, as it may cause drowsiness.
3
Do not exceed the recommended dose of Paracetamol; high doses can cause liver damage.
4
Avoid alcohol while taking this medicine to prevent liver toxicity and increased drowsiness.
5
Consult your doctor if symptoms persist beyond 7 days or if they worsen.
6
Inform your doctor if you have liver or kidney disease before taking this medicine.
7
Do not use this medicine for self-medication in children without medical advice.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Sneezing
This medicine is commonly prescribed for allergic sneezing.
Likely Use
✅
Runny nose
This medicine helps reduce runny nose due to allergies or cold.
Likely Use
✅
Fever
Paracetamol component helps reduce mild fever.
Likely Use
✅
Body ache
Paracetamol component provides relief from mild to moderate pain.
Likely Use
✅
Itchy eyes
Cetirizine helps relieve itchy, watery eyes due to allergies.
Likely Use
❌
Chest pain
This medicine is not intended for chest pain; seek immediate medical attention.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionCetirizine is rapidly absorbed after oral administration, with peak plasma concentrations reached in about 1 hour. Paracetamol is also rapidly and completely absorbed from the gastrointestinal tract, with peak plasma levels occurring within 0.5 to 2 hours. Food may delay the absorption of both components slightly but does not significantly affect the extent of absorption.
DistributionCetirizine is widely distributed throughout the body, including into the skin, and has a volume of distribution of approximately 0.5 L/kg. It is about 93% bound to plasma proteins. Paracetamol is distributed widely in body fluids and tissues, with a volume of distribution of about 0.9 L/kg. It is only minimally bound to plasma proteins (about 10-25%).
Protein BindingCetirizine: approximately 93% bound to plasma proteins. Paracetamol: approximately 10-25% bound to plasma proteins.
MetabolismCetirizine undergoes minimal hepatic metabolism; it is primarily excreted unchanged in the urine. Paracetamol is extensively metabolized in the liver, primarily by glucuronidation and sulfation, with a small fraction metabolized by cytochrome P450 2E1 to a toxic intermediate (N-acetyl-p-benzoquinone imine, NAPQI), which is detoxified by glutathione. In overdose, glutathione stores are depleted, leading to liver damage.
Half-LifeCetirizine: approximately 8-10 hours in adults. Paracetamol: approximately 2-3 hours in adults with normal liver function.
ExcretionCetirizine is primarily excreted unchanged in the urine (about 70%) and feces (about 10%). Paracetamol is excreted in the urine as glucuronide and sulfate conjugates (about 90%), with a small amount excreted unchanged.
BioavailabilityCetirizine: approximately 70% oral bioavailability. Paracetamol: approximately 80-100% oral bioavailability.
Onset of ActionCetirizine: onset of antihistaminic effect within 1 hour. Paracetamol: onset of analgesic and antipyretic effect within 30-60 minutes.
Peak Plasma TimeCetirizine: 1 hour. Paracetamol: 0.5-2 hours.
Duration of ActionCetirizine: 24 hours. Paracetamol: 4-6 hours.

How It Works

This medicine combines two active ingredients with distinct mechanisms. Cetirizine is a second-generation antihistamine that selectively antagonizes peripheral H1 receptors, reducing allergic responses such as sneezing, itching, and runny nose. It also has some mast cell stabilizing properties. Paracetamol (acetaminophen) acts primarily in the central nervous system by inhibiting prostaglandin synthesis, which leads to reduction of fever and pain. The exact mechanism of Paracetamol is not fully understood, but it is believed to involve inhibition of cyclooxygenase (COX) enzymes in the brain and spinal cord, and possibly activation of descending serotonergic pathways. Together, these actions provide symptomatic relief from allergic and cold symptoms.

Mechanism Steps

1
Cetirizine binds to H1 receptors: Cetirizine competitively blocks histamine at H1 receptor sites, preventing histamine-mediated allergic responses such as vasodilation, increased vascular permeability, and sensory nerve stimulation.
2
Reduction of allergic symptoms: By blocking H1 receptors, cetirizine reduces sneezing, runny nose, itching, and watery eyes.
3
Paracetamol acts centrally: Paracetamol inhibits prostaglandin synthesis in the central nervous system, primarily in the hypothalamus, leading to reduction of fever.
4
Analgesic effect: Paracetamol also elevates the pain threshold by acting on the CNS, providing relief from mild to moderate pain.

💡 How to Take ccfs tablet

Strength: Tablet containing Cetirizine 10 mg and Paracetamol 500 mg.

1Take this medicine orally with a glass of water.
2It can be taken with or without food, but taking it with food may reduce stomach upset.
3Swallow the tablet whole; do not crush or chew.
4Follow the dosage and duration prescribed by your doctor.
5Do not exceed the recommended dose.

Dosage Information

Adult DosageThe usual adult dose is one tablet taken orally every 8 to 12 hours as needed for symptoms, not to exceed 3 tablets in 24 hours. However, the dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Do not exceed the recommended dose. For allergic rhinitis, it may be taken once daily or as directed. Always follow your doctor's prescription.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more sensitive to the side effects, especially drowsiness and anticholinergic effects. Dose adjustment may be necessary based on renal and hepatic function. Consult a doctor for appropriate dosing.
Renal ImpairmentIn patients with renal impairment, dose reduction may be required. For creatinine clearance 30-50 mL/min, consider reducing dose or increasing dosing interval. For creatinine clearance <30 mL/min, use with caution and consult a doctor. Not recommended in severe renal impairment (CrCl <10 mL/min).
Hepatic ImpairmentIn patients with mild to moderate hepatic impairment, dose reduction or increased dosing interval may be necessary. Avoid use in severe hepatic impairment. Consult a doctor for appropriate dosing.
Maximum Daily DoseMaximum daily dose: 3 tablets in 24 hours (Cetirizine 30 mg and Paracetamol 1500 mg). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of liver toxicity and drowsiness.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of ccfs tablet

✅ Common Side Effects

Drowsiness (Common (10-14%))
Avoid driving or operating machinery until you know how this medicine affects you. If drowsiness persists, consult your doctor.
Dry mouth (Common (5-10%))
Sip water frequently or chew sugarless gum. If it becomes bothersome, consult your doctor.
Fatigue (Common (5-10%))
Get adequate rest. If fatigue is severe or persistent, consult your doctor.
Nausea (Common (2-5%))
Take with food to reduce nausea. If it continues, consult your doctor.
Headache (Common (2-5%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience rash, itching, swelling of face, lips, tongue, or throat, difficulty breathing, or dizziness.
Liver damage (hepatotoxicity) (Rare (<0.1%) with normal doses; higher with overdose)
Seek immediate medical attention if you notice yellowing of skin or eyes, dark urine, severe abdominal pain, or unusual tiredness.
Severe skin reactions (Stevens-Johnson syndrome, toxic epidermal necrolysis) (Very rare (<0.01%))
Seek immediate medical attention if you develop a rash with blisters, peeling skin, or sores in the mouth.
Blood disorders (thrombocytopenia, leukopenia) (Very rare (<0.01%))
Consult your doctor if you experience unusual bleeding, bruising, or signs of infection.

⚠️ Rare Side Effects

Tachycardia
Consult your doctor if you experience palpitations or rapid heartbeat.
Confusion
Consult your doctor if you experience confusion or disorientation.
Urinary retention
Consult your doctor if you have difficulty urinating.
Blurred vision
Consult your doctor if vision changes occur.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Alcohol Major
CNS depressants Major
Carbamazepine Moderate
Phenytoin Moderate
Rifampicin Moderate
Theophylline Moderate
Antacids Minor
Cholestyramine Minor

🚨 Major Interactions

  • Warfarin
  • Alcohol
  • Other CNS depressants (e.g., benzodiazepines, opioids, antipsychotics)

⚡ Moderate Interactions

  • Carbamazepine
  • Phenytoin
  • Rifampicin
  • Theophylline

🍷 Alcohol Interaction

Avoid consuming alcohol while taking this medicine. Alcohol increases the risk of liver damage from Paracetamol and can enhance the sedative effects of Cetirizine, leading to increased drowsiness and impaired coordination.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Hypersensitivity to Cetirizine, Paracetamol, or any component of the formulation","Severe liver disease or active liver disease","Severe kidney impairment (creatinine clearance

⚠️ Warnings & Precautions

["Do not exceed the recommended dose of Paracetamol; high doses can cause liver damage.","Avoid alcohol while taking this medicine.","May cause drowsiness; avoid driving or operating machinery until you know how it affects you.","Use with caution in patients with liver or kidney disease.","Consult a doctor if symptoms persist beyond 7 days or worsen.","Do not use for self-medication in children without medical advice.","Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding."]

🤱 Lactation Safety

Cetirizine and Paracetamol are excreted in breast milk in small amounts. Caution is advised. Consult your doctor before use during breastfeeding.

💊 Overdose Management

Overdose of Paracetamol can cause severe liver damage, which may be delayed. Symptoms of overdose may include nausea, vomiting, abdominal pain, and loss of appetite. If you suspect an overdose, seek immediate medical attention even if you feel well. The antidote N-acetylcysteine is most effective when given within 8-10 hours of ingestion. Cetirizine overdose may cause drowsiness, agitation, or tachycardia; supportive care is usually sufficient. Contact a poison control center or emergency room immediately.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have liver or kidney disease, alcoholism, or any other medical condition. Do not exceed the recommended dose, as high doses of Paracetamol can cause serious liver damage. Avoid consuming alcohol while taking this medicine, as it can increase the risk of liver toxicity and enhance drowsiness. This medicine may cause drowsiness; avoid driving or operating heavy machinery until you know how it affects you. Do not use this medicine for more than 7 days without consulting a doctor. If you are pregnant or breastfeeding, consult your doctor before use. Keep out of reach of children. Store at room temperature away from moisture and heat. Do not use if the packaging is damaged or if the expiry date has passed.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially drowsiness and dry mouth. Dose adjustment may be needed based on kidney and liver function. Consult a doctor for appropriate dosing.

🤰 Pregnancy Planning (TTC)

Consult your doctor before taking this medicine if you are pregnant, planning to become pregnant, or breastfeeding. The safety of this combination during pregnancy is not well established.

🏥 Post-Surgery Considerations

Consult your doctor before taking this medicine after surgery, as it may interact with other medications or affect recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may cause drowsiness or interact with anesthetics.

💚 Lifestyle Tips for Better Results

🏃
Stay hydrated by drinking plenty of fluids.
🥗
Get adequate rest to help your body recover.
😴
Avoid exposure to allergens like dust, pollen, and pet dander.
💧
Use a humidifier to ease nasal congestion.
🧘
Practice good hand hygiene to prevent infections.
🌞
Avoid alcohol and smoking.

🏋️ Exercise Considerations

This medicine may cause drowsiness, so avoid strenuous exercise or activities requiring alertness until you know how it affects you. Light exercise like walking may be fine if you feel up to it.

🥗 Diet Recommendations

Include warm fluids like soups and herbal teas.
Eat light, easily digestible meals.
Avoid spicy and oily foods that may upset your stomach.
Include vitamin C-rich fruits like oranges and lemons.
Stay well hydrated.

💼 Impact on Daily Work & Life

This medicine may cause drowsiness, which can affect your ability to drive or operate machinery. It is advisable to avoid such activities until you know how the medicine affects you. It may also reduce your concentration, so take precautions at work.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your symptoms do not improve within 7 days, if they worsen, or if you experience any serious side effects. Do not stop abruptly if you have been taking it for a long time without medical advice.

📅 Long-Term Use Effects

Long-term use of this medicine, especially at high doses, can increase the risk of liver damage due to Paracetamol. Regular monitoring of liver function may be required if used for extended periods. Cetirizine may cause tolerance or persistent drowsiness. It is not recommended for long-term use without medical supervision.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Saline nasal rinse

Helps relieve nasal congestion and flush out allergens.

Evidence: Well-established
Steam inhalation

Can help ease nasal congestion and soothe irritated airways.

Evidence: Limited
Allergen avoidance

Reducing exposure to allergens can decrease the need for medication.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you have a fever, consult your doctor before vaccination.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with a copy of your prescription. Store it at room temperature, away from direct sunlight and moisture. If crossing time zones, adjust dosing intervals as advised by your doctor. Check customs regulations for carrying medications. Always keep it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old woman with seasonal allergies
She experienced sneezing, runny nose, and itchy eyes every spring. Her doctor prescribed this medicine. She took it as directed and noticed significant relief within an hour. She was advised to avoid driving due to drowsiness and to take it with food to prevent stomach upset.
💡 Lesson: Taking this medicine as prescribed provides effective relief from allergy symptoms, but precautions like avoiding driving and taking with food are important.
👤 A 50-year-old man with common cold and fever
He had a cold with mild fever and body ache. He took this medicine every 8 hours as needed. His fever subsided and body ache reduced. He was cautioned not to exceed the dose and to avoid alcohol. He recovered within 3 days.
💡 Lesson: This medicine effectively relieves cold symptoms and fever when taken as directed, but adherence to dosage limits is crucial to prevent liver damage.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Cetirizine starts working within 1 hour, and Paracetamol within 30-60 minutes. You may feel relief from symptoms within 1-2 hours.

Q: Can I take this medicine on an empty stomach?

A: It can be taken with or without food, but taking it with food may reduce stomach upset.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

Q: Is it safe to take this medicine daily?

A: It should not be taken daily for more than 7 days without consulting a doctor. Prolonged use may increase the risk of side effects.

Q: Can I take this medicine with alcohol?

A: No, alcohol should be avoided as it increases the risk of liver toxicity and drowsiness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe during pregnancy?
  • Can I take it with other cold medicines?

🔄 Substitutes for ccfs tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure allergies permanently.
    Fact: This medicine only provides symptomatic relief; it does not cure allergies.
  • Myth: It is safe to take this medicine with alcohol.
    Fact: Alcohol should be avoided as it increases the risk of liver toxicity and drowsiness.
  • Myth: This medicine is safe for children without a prescription.
    Fact: It should only be given to children under medical supervision.
  • Myth: Taking more than the recommended dose will work faster.
    Fact: Taking more can cause serious liver damage and other side effects.

🔄 Alternative Options

Generic Alternatives

  • Cetirizine + Paracetamol (generic)

Brand Alternatives

  • Cetzine Plus
  • Alerid Plus
  • Okacet Plus
  • Zyrtec Plus

📊 Comparison with Similar Medicines

[{"medicine":"Cetirizine + Paracetamol","composition":"Cetirizine 10 mg + Paracetamol 500 mg","onset":"1 hour","duration":"24 hours for Cetirizine, 4-6 hours for Paracetamol","sedation":"Moderate"},{"medicine":"Levocetirizine + Paracetamol","composition":"Levocetirizine 5 mg + Paracetamol 500 mg","onset":"1 hour","duration":"24 hours for Levocetirizine, 4-6 hours for Paracetamol","sedation":"Less sedating"},{"medicine":"Fexofenadine + Paracetamol","composition":"Fexofenadine 120 mg + Paracetamol 500 mg","onset":"1-2 hours","duration":"24 hours for Fexofenadine, 4-6 hours for Paracetamol","sedation":"Non-sedating"}]

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