Accuzon 2g Injection (Ceftriaxone): Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing, wheezing, or swelling of the face, lips, or throat
- Widespread blistering rash or peeling skin
- Severe, watery, or bloody diarrhoea
- Severe abdominal pain, especially in the upper abdomen
- Decreased urine output or swelling of the legs
- Unusual bruising or bleeding
- Yellowing of the skin or eyes
- Seizures or confusion
If experiencing severe symptoms, call emergency services immediately.
What is cbzone 2gm injection used for?
This medicine is a strong intravenous antibiotic containing ceftriaxone 2 grams. It is used to treat serious bacterial infections such as pneumonia, meningitis, and sepsis. It works by breaking down the bacterial cell wall, causing the bacteria to die. It is given only by a healthcare professional and must not be mixed with calcium-containing solutions in newborns.
- Generic Name: Ceftriaxone
- Manufacturer: Chandra Bhagat Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 cbzone 2gm injection के बारे में (Hindi Summary)
उपयोग: यह दवा सेफ्ट्रिएक्सोन 2 ग्राम इंजेक्शन है, जो एक शक्तिशाली एंटीबायोटिक है। इसका उपयोग गंभीर बैक्टीरियल संक्रमणों जैसे निमोनिया, मेनिनजाइटिस, सेप्सिस, मूत्र मार्ग संक्रमण और गोनोरिया के इलाज के लिए किया जाता है। यह दवा बैक्टीरिया की कोशिका भित्ति को तोड़कर उन्हें मार देती है। यह केवल डॉक्टर या नर्स द्वारा नस में दी जाती है। वायरल संक्रमण जैसे सर्दी-जुकाम पर यह दवा असर नहीं करती।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में इंजेक्शन वाली जगह पर दर्द, लालिमा या सूजन, दस्त, जी मिचलाना, उल्टी, हल्का दाना और सिरदर्द शामिल हैं। कभी-कभी गंभीर एलर्जी, त्वचा पर गंभीर प्रतिक्रिया, पित्ताशय में कीचड़, और खून की कोशिकाओं में कमी हो सकती है। अगर सांस लेने में तकलीफ, चेहरे या गले में सूजन, या गंभीर दस्त हो तो तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा नस में दी जानी चाहिए। इसे खुद से न लगाएं। इससे पहले कि आपको यह दवा दी जाए, अपनी सभी एलर्जी के बारे में डॉक्टर को बताएं, खासकर पेनिसिलिन या सेफलोस्पोरिन से। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। इस दवा को कैल्शियम वाले घोल के साथ न मिलाएं, खासकर नवजात शिशुओं में। इलाज पूरा करें, बीच में न छोड़ें।
💊 cbzone 2gm injection Uses & Benefits
[{"condition":"Community-acquired pneumonia","description":"Used to treat moderate to severe bacterial pneumonia caused by susceptible organisms, often in combination with other antibiotics.","evidence":"Well-established"},{"condition":"Bacterial meningitis","description":"A first-line antibiotic for many causes of bacterial meningitis in adults and children, given intravenously at high doses.","evidence":"Well-established"},{"condition":"Sepsis and bloodstream infections","description":"Used empirically and after culture results to treat serious bloodstream infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Complicated urinary tract infections","description":"Effective against many bacteria that cause kidney and bladder infections requiring intravenous therapy.","evidence":"Well-established"},{"condition":"Gonorrhoea","description":"Used as part of recommended regimens for uncomplicated gonococcal infections, often with another antibiotic.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Treats serious cellulitis, abscesses, and wound infections caused by susceptible bacteria.","evidence":"Well-established"},{"condition":"Intra-abdominal infections","description":"Used with other antibiotics to cover a broad range of bacteria in complicated intra-abdominal infections.","evidence":"Well-established"},{"condition":"Bone and joint infections","description":"May be used for osteomyelitis and septic arthritis when the causative organism is susceptible.","evidence":"Moderate"}]
Off-label uses: [{"condition":"Lyme disease with neurological involvement","description":"Sometimes used as an alternative to other intravenous antibiotics for certain manifestations of Lyme disease.","evidence":"Limited"},{"condition":"Prophylaxis in certain surgical procedures","description":"Occasionally used for surgical prophylaxis when standard agents are not suitable, though this is not a primary labelled use.","evidence":"Limited"}]
Primary treatment for: Serious bacterial infections
Also treats: Pneumonia, Meningitis, Sepsis, Urinary tract infections, Gonorrhoea, Skin infections, Intra-abdominal infections, Bone and joint infections
📋 Drug Information
| Generic Name(s) | Ceftriaxone |
| Brand Name | Accuzon 1g Injection |
| Manufacturer | Chandra Bhagat Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 3 generation |
| Route of Administration | Intravenous (into a vein). This medicine may also be given intramuscularly in some situations, but the intravenous route is preferred for serious infections |
| Storage | Store this medicine as directed on the label, usually at room temperature between 15°C and 30°C, away from light and moisture. Once reconstituted, the solution should be used within the time specified by the manufacturer, often within 6 to 24 hours if kept at room temperature, or longer if refrigerated. Do not freeze. Keep out of reach of children. |
| Shelf Life | The shelf life of this medicine is typically 24 to 36 months from the date of manufacture, depending on the manufacturer and packaging. Always check the expiry date before use. Once reconstituted, use within the recommended time. |
| WHO Guideline | The World Health Organization includes ceftriaxone in its Model List of Essential Medicines. It is recommended for several conditions, including severe pneumonia, meningitis, and gonorrhoea, but the exact recommendations depend on the specific infection and local resistance patterns. Always follow your doctor's advice. |
| ICMR Guideline | The Indian Council of Medical Research has published treatment guidelines for various infections that include ceftriaxone as an option. These guidelines emphasise using antibiotics wisely and only when needed. Your doctor will follow the most appropriate guideline for your condition. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine is a third-generation cephalosporin antibiotic that kills bacteria by interfering with the synthesis of the bacterial cell wall. It binds to specific penicillin-binding proteins located inside the bacterial cell wall, which stops the cross-linking of peptidoglycan strands. Without proper cross-linking, the bacterial cell wall becomes weak and the cell bursts under normal osmotic pressure. This medicine is bactericidal, meaning it directly kills susceptible bacteria rather than just stopping their growth. It is stable against many beta-lactamase enzymes produced by bacteria, which is why it remains effective against a broad range of organisms.
Mechanism Steps
💡 How to Take cbzone 2gm injection
Strength: This medicine is supplied as a sterile powder for injection containing ceftriaxone 2 grams. It is reconstituted with a suitable diluent before intravenous administration.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 1 to 2 grams given intravenously once daily, or in divided doses every 12 hours for severe infections. For meningitis, doses up to 2 grams every 12 hours may be used. For uncomplicated gonorrhoea, a single 500 mg intramuscular dose is often used, but the intravenous form can also be given. The exact dose and duration depend on the type and severity of the infection, your kidney and liver function, and your weight. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing of this medicine is based on weight and the type of infection. It is not established from available information for all situations. A typical range is 50 to 75 mg per kg per day, but doses for serious infections like meningitis may be higher. Pediatric dosing must be determined by a pediatrician. Do not attempt to calculate or give this medicine to a child without medical supervision. |
| Elderly Dosage | Elderly patients usually receive the same dose as younger adults, but they are more likely to have reduced kidney function. Your doctor may check your kidney function and adjust the dose if needed. Elderly patients should be monitored closely for side effects, especially confusion, falls, and kidney problems. |
| Renal Impairment | In people with mild to moderate kidney problems, the usual dose of this medicine can often be given without adjustment. In severe kidney failure, the dose may need to be reduced or the interval between doses lengthened. Your doctor will decide the exact dose based on your kidney function tests. Dose must be individualized by a qualified clinician. |
| Hepatic Impairment | In people with liver problems, this medicine is usually given at the normal dose because it is not heavily metabolised by the liver. However, if you have both liver and kidney problems, your doctor may adjust the dose and monitor you more closely. Dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum recommended daily dose of this medicine is 4 grams, except in certain serious infections such as meningitis where up to 4 grams per day may be used. Doses above 4 grams per day are not recommended. The exact maximum for you will be decided by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of cbzone 2gm injection
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Calcium-containing IV solutions | Major | |
| Warfarin | Major | |
| Aminoglycosides | Major | |
| Chloramphenicol | Major | |
| Loop diuretics | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Antacids | Minor | |
| Vitamin K antagonists | Minor | |
| Alcohol | Minor |
🚨 Major Interactions
- Calcium-containing intravenous solutions
- Warfarin and other anticoagulants
- Aminoglycosides (e.g., gentamicin, amikacin)
- Chloramphenicol
⚡ Moderate Interactions
- Loop diuretics (e.g., furosemide)
- Probenecid
- Oral contraceptives
🍷 Alcohol Interaction
There is no direct interaction between this medicine and alcohol. However, drinking alcohol while you are fighting a serious infection can worsen dehydration, interfere with recovery, and increase the risk of liver strain if you are also taking other medicines. It is best to avoid alcohol until you have fully recovered and your doctor says it is safe.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known severe allergy to ceftriaxone or any other cephalosporin antibiotic","Previous severe allergic reaction to penicillin (cross-reactivity possible)","Use in newborns (up to 28 days) who are receiving calcium-containing intravenous solutions","Use in newborns with jaundice or who are at risk of jaundice","Use in people who have had a serious reaction to lidocaine if the medicine is mixed with lidocaine for intramuscular injection"]
⚠️ Warnings & Precautions
["This medicine must be given only by a healthcare professional. Do not attempt to inject it yourself.","Tell your doctor about all your allergies before receiving this medicine.","Serious allergic reactions can occur. Stop the infusion and seek emergency care if you have trouble breathing or swelling of the face or throat.","Diarrhoea during or after treatment may be a sign of a serious intestinal infection. Do not treat it with over-the-counter anti-diarrhoeal medicines without asking your doctor.","This medicine can cause gallbladder sludge, which may cause abdominal pain. This usually resolves after treatment is stopped.","Use with caution in people with kidney or liver problems. Your doctor may adjust the dose or monitor you more closely.","This medicine may interfere with some blood tests, so tell the laboratory staff that you are receiving it.","Do not mix this medicine with calcium-containing solutions or other medicines unless your doctor or pharmacist confirms it is safe."]
🤱 Lactation Safety
This medicine passes into breast milk in small amounts. It is generally considered compatible with breastfeeding, but you should watch your baby for diarrhoea, thrush, or rash. If you notice any of these, contact your doctor. The decision to use this medicine while breastfeeding should be made with your healthcare provider.
💊 Overdose Management
Overdose with this medicine is unlikely because it is given by a healthcare professional. If too much is given, the main risk is increased side effects such as nausea, diarrhoea, and blood abnormalities. Treatment is supportive and may include monitoring of blood counts, kidney function, and electrolytes. There is no specific antidote. In case of accidental overdose, contact a doctor or poison control centre immediately.
⏰ Missed Dose
This medicine is given by a healthcare professional, so a missed dose is unlikely. If you miss a scheduled dose, contact your doctor or nurse as soon as possible. They will decide whether to give the dose late or skip it and adjust your schedule. Do not try to make up for a missed dose by taking extra medicine.
Additional Safety Advice
This medicine must be given only by a doctor or nurse through a vein, and you should not attempt to inject it yourself at home. Tell your doctor about all your allergies, especially to penicillin or other cephalosporin antibiotics, before receiving this medicine. Inform your healthcare team if you are pregnant, planning pregnancy, or breastfeeding, because the decision to use this medicine will be made after weighing benefits and risks. Do not mix this medicine with calcium-containing solutions, particularly in newborns, as this can cause a dangerous reaction. If you develop severe diarrhoea, blood in stool, or signs of an allergic reaction such as rash, swelling, or breathing difficulty, seek medical help immediately. Keep all follow-up appointments so your doctor can monitor your response and check for side effects. Do not stop treatment early unless your doctor tells you to, even if you feel better, because incomplete treatment can allow the infection to return.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function and may need a lower dose or longer intervals between doses. They are also more prone to confusion, falls, and dehydration during infection. Monitor elderly patients closely for these issues and ensure they stay well hydrated.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, tell your doctor before receiving this medicine. Ceftriaxone is generally considered safe in pregnancy when needed for a bacterial infection. Your doctor will weigh the benefits and risks. If you become pregnant during treatment, contact your doctor immediately.
🏥 Post-Surgery Considerations
This medicine is sometimes used after surgery to treat or prevent infection. If you have recently had surgery and are given this medicine, follow your surgeon's instructions carefully. Report any signs of infection at the surgical site, such as redness, swelling, or discharge.
🦷 Dental Procedures
Tell your dentist if you are receiving this medicine or have recently received it. In some cases, your dentist may need to coordinate with your doctor before performing dental work, especially if you are at risk of infection. This medicine is not a substitute for dental treatment.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While you are recovering from a serious infection, you should avoid strenuous exercise. Light activity such as walking is fine if you feel up to it. If you feel dizzy, short of breath, or very tired, stop and rest. Ask your doctor when you can return to your normal exercise routine.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is usually given in a hospital or clinic, so you may need to take time off work during treatment. You may feel tired or unwell for a few days. Do not drive or operate heavy machinery if you feel dizzy or weak. Ask your doctor when you can safely return to work.
🛑 When to Stop This Medicine
Do not stop this medicine on your own. Your doctor will decide when to stop based on your response to treatment and test results. If you develop a serious side effect, your doctor may stop the medicine and switch you to another antibiotic. Always consult your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine is not common because it is usually given for a short course. If used for a long time, it can lead to antibiotic resistance, fungal superinfections, and changes in blood counts. Prolonged use may also increase the risk of gallbladder sludge and kidney problems. Your doctor will monitor you with blood tests if you need treatment for more than a few days.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Once you are improving, your doctor may switch you to oral antibiotics to complete the course.
Evidence: Well-establishedIf you are allergic to ceftriaxone or the bacteria are resistant, other antibiotics may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with most vaccines. However, if you are due for a live vaccine, tell your doctor that you are receiving this medicine. In general, antibiotics do not reduce vaccine effectiveness, but your doctor will advise you based on your specific situation.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not freeze
✅ DO
Keep in original packaging
❌ DON'T
Do not use if the powder looks discoloured or the vial is damaged
✅ DO
Use reconstituted solution within the recommended time
❌ DON'T
Do not store reconstituted solution for longer than advised
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in a bathroom or damp place
✈️ Traveling with This Medicine
This medicine is given in a hospital or clinic, so travel is usually not a concern during treatment. If you need to travel after treatment, carry a copy of your prescription and discharge summary. Keep the medicine in its original packaging if you are carrying it, and store it at room temperature away from direct sunlight. If you are travelling across time zones and still need doses, ask your doctor how to adjust the schedule. Always declare your medicines at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel better within 24 to 72 hours, but it can take longer depending on the infection. Always complete the full course prescribed by your doctor.
A: Some patients can receive this medicine at home through a home infusion service, but this must be arranged by your doctor. Most people receive it in a hospital or clinic.
A: Your doctor may need to adjust the dose or monitor your kidney function more closely. Tell your doctor about any kidney problems before receiving this medicine.
A: This medicine can cause dizziness or tiredness in some people. Do not drive or operate machinery if you feel unwell or dizzy.
A: Seek emergency medical help immediately if you have difficulty breathing, swelling of the face or throat, or a severe rash.
🤔 Common Patient Concerns
🔄 Substitutes for cbzone 2gm injection
View AllAlternative brands with exact same active ingredient:
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oframax 2gm injectionSun Pharmaceutical Industries Ltd ₹106.64 11.2% COSTLIER
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a cef 2gm injectionAAA Pharma Trade Pvt Ltd ₹117.05 22.1% COSTLIER
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nexocef 2gm injectionNectar Biopharma Pvt Limited ₹121.88 27.1% COSTLIER
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Rixone 2gm InjectionRishab Healthcare pvt. Ltd. ₹121.88 27.1% COSTLIER
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supercef 2gm injectionAkumentis Healthcare Ltd ₹122.06 27.3% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure viral infections like the common cold.
Fact: This medicine only works against bacteria. It has no effect on viruses. - Myth: You can stop this medicine as soon as you feel better.
Fact: You must complete the full course prescribed by your doctor to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe to mix with any other intravenous fluid.
Fact: This medicine must not be mixed with calcium-containing solutions, especially in newborns, because it can cause dangerous precipitates. - Myth: This medicine is a painkiller.
Fact: This medicine is an antibiotic. It treats infection but does not directly relieve pain.
🔄 Alternative Options
Generic Alternatives
- Ceftriaxone 2g injection
Brand Alternatives
- Accuzon 2g injection