cavidin 600mg tablet - Rifampicin (600mg) medicine

cavidin 600mg tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Wockhardt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 26, 2026
โš ๏ธ Hepatotoxicity Risk ๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
Dr. SaathiMed Expert Panel | Jun 26, 2026

What is cavidin 600mg tablet used for?

Coxid (Rifampicin) is used to treat ANTI INFECTIVES. It contains Rifampicin (600mg), which Inhibits bacterial DNA-dependent RNA polymerase by binding to beta subunit.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Rifampicin
  • Manufacturer: Wockhardt Ltd
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š cavidin 600mg tablet Uses & Benefits

Tuberculosis (first-line), leprosy, atypical mycobacterial infections, staphylococcal infections (combination therapy).

Off-label uses: Prosthetic valve endocarditis (Staphylococcus), brucellosis, leishmaniasis.

๐Ÿ“‹ Drug Information

Generic Name(s)Rifampicin
Brand NameCoxid
ManufacturerWockhardt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI INFECTIVES
Action ClassRNA polymerase inhibitors- Rifamycins
Route of AdministrationOral
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; food reduces absorption.
DistributionWidely distributed; penetrates tissues and CSF.
Protein Binding80-90%
MetabolismHepatic; deacetylated to active metabolite; induces CYP450 enzymes.
Half-Life3-5 hours (initial), prolonged with hepatic impairment
ExcretionBiliary (60-65%) and renal (30%)
Bioavailability90-95%
Onset of Action1-2 hours
Peak Plasma Time2-4 hours
Duration of Action12-24 hours

How It Works

Inhibits bacterial DNA-dependent RNA polymerase by binding to beta subunit.

Mechanism Steps

1Binds to beta subunit of bacterial DNA-dependent RNA polymerase.
2Inhibits RNA synthesis by blocking transcription initiation.
3Bactericidal effect on susceptible organisms.

๐Ÿ’ก How to Take cavidin 600mg tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of cavidin 600mg tablet

โœ… Common Side Effects

  • Nausea
  • vomiting
  • diarrhea
  • anorexia
  • red-orange discoloration of urine/sweat/tears

๐Ÿšจ Serious Side Effects

  • Hepatotoxicity
  • thrombocytopenia
  • hemolytic anemia
  • acute renal failure
  • Stevens-Johnson syndrome

โš ๏ธ Rare Side Effects

  • Pseudomembranous colitis
  • pancreatitis
  • interstitial nephritis
  • optic neuritis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Decreased anticoagulant effect; increased warfarin metabolism.
Oral contraceptives Major Reduced contraceptive efficacy; enzyme induction.
Antiretrovirals Major Reduced antiretroviral levels; enzyme induction.
Azole antifungals Major Reduced antifungal levels; enzyme induction.
Phenytoin Major Decreased phenytoin levels; enzyme induction.
Theophylline Major Decreased theophylline levels; enzyme induction.

๐Ÿšจ Major Interactions

  • Warfarin
  • Oral contraceptives
  • Antiretrovirals (protease inhibitors, NNRTIs)
  • Antifungals (azoles)
  • Phenytoin
  • Theophylline

โšก Moderate Interactions

  • Corticosteroids
  • Cyclosporine
  • Tacrolimus
  • Verapamil
  • Diltiazem

โ„น๏ธ Minor Interactions

  • Acetaminophen
  • Chloramphenicol
  • Clofibrate

๐Ÿฝ๏ธ Food Interactions

High-fat meals decrease absorption; take on empty stomach.

๐Ÿท Alcohol Interaction

Increased hepatotoxicity risk; avoid alcohol.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to rifampicin or any component; jaundice; concurrent use of ritonavir-boosted protease inhibitors.

๐Ÿ“Š Monitoring Parameters

Liver function tests (AST, ALT, bilirubin), renal function, CBC, signs of hepatotoxicity.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Gastric lavage, activated charcoal, supportive care; monitor liver function.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

Dr. SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 26, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for cavidin 600mg tablet

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Alternative brands with exact same active ingredient (Rifampicin (600mg)):

Medical Note: Always consult your doctor before switching medications.

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