carvalol 12.5mg tablet

4.3 (15 reviews)

Carvedilol (12.5mg)

🏭 Psychocare Health Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 23, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 23, 2026

What is carvalol 12.5mg tablet used for?

Cardivas 3.125 Tablet (Carvedilol) is used to treat CARDIAC. It contains Carvedilol (12.5mg), which Blocks beta-1, beta-2, and alpha-1 adrenergic receptors, leading to vasodilation. Always consult your doctor before use. Take as prescribed.

Generic Name: Carvedilol
Manufacturer: Psychocare Health Pvt Ltd
Form: Allopathy
Pregnancy Category: C
Prescription Required: Yes

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 carvalol 12.5mg tablet Uses & Benefits

Hypertension, chronic heart failure, left ventricular dysfunction after myocardial infarction.

Off-label uses: Migraine prophylaxis, angina, arrhythmias, portal hypertension.

📋 Drug Information

Generic Name(s)	Carvedilol
Brand Name	Cardivas 3.125 Tablet
Manufacturer	Psychocare Health Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	CARDIAC
Action Class	Alpha & beta blocker
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from light and moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed after oral administration; peak plasma concentrations occur within 1-2 hours.

DistributionExtensively distributed into tissues; volume of distribution approximately 115 L.

Protein BindingApproximately 98% bound to plasma proteins (primarily albumin).

MetabolismExtensively metabolized in the liver via CYP2D6 and CYP2C9; undergoes glucuronidation and sulfation.

Half-Life7-10 hours

ExcretionPrimarily excreted in feces (60%) and urine (16%) as metabolites; less than 2% excreted unchanged.

BioavailabilityApproximately 25-35% due to first-pass metabolism.

Onset of Action1-2 hours

Peak Plasma Time1-2 hours

Duration of Action12-24 hours

How It Works

Blocks beta-1, beta-2, and alpha-1 adrenergic receptors, leading to vasodilation and reduced heart rate.

Mechanism Steps

1Carvedilol competitively blocks beta-1 adrenergic receptors in the heart, reducing heart rate and contractility.

2Blocks beta-2 adrenergic receptors in vascular smooth muscle, preventing vasodilation but also reducing bronchodilation.

3Blocks alpha-1 adrenergic receptors in vascular smooth muscle, causing vasodilation and reducing peripheral vascular resistance.

💡 How to Take carvalol 12.5mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of carvalol 12.5mg tablet

✅ Common Side Effects

Dizziness
Fatigue
Hypotension
Bradycardia
Diarrhea
Nausea
Weight gain

🚨 Serious Side Effects

Heart block
Severe bradycardia
Bronchospasm
Hepatic injury
Peripheral ischemia

⚠️ Rare Side Effects

Stevens-Johnson syndrome
Anaphylaxis
Thrombocytopenia
Alopecia

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Verapamil	Major	Increased risk of bradycardia and heart block
Digoxin	Major	Increased digoxin levels and risk of toxicity
Insulin	Major	Enhanced hypoglycemic effect; may mask tachycardia

🚨 Major Interactions

CYP2D6 inhibitors (e.g., fluoxetine, paroxetine)
CYP2C9 inhibitors (e.g., amiodarone)
Calcium channel blockers (e.g., verapamil, diltiazem)
Digoxin
Clonidine
Insulin and oral hypoglycemics

⚡ Moderate Interactions

NSAIDs
Rifampin
Barbiturates
Cimetidine

ℹ️ Minor Interactions

Antacids
Grapefruit juice

🍽️ Food Interactions

Food delays absorption but does not affect bioavailability; take with food to reduce orthostatic hypotension.

🍷 Alcohol Interaction

Alcohol may enhance hypotensive effects; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Bronchial asthma, severe bradycardia, heart block (2nd or 3rd degree), cardiogenic shock, decompensated heart failure, severe hepatic impairment.

📊 Monitoring Parameters

Blood pressure, heart rate, ECG, blood glucose (in diabetics), renal function, hepatic function.

🤱 Lactation Safety

Excreted in breast milk; use with caution.

💊 Overdose Management

Supportive care; administer atropine for bradycardia, glucagon for myocardial depression, and vasopressors for hypotension.

⏰ Missed Dose

Take as soon as remembered unless close to next dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 23, 2026

🔗 View Profile

🔄 Substitutes for carvalol 12.5mg tablet

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Alternative brands with exact same active ingredient (Carvedilol (12.5mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Certified Buyer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Trusted Reviewer Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

carvalol 12.5mg tablet

What is carvalol 12.5mg tablet used for?

💊 carvalol 12.5mg tablet Uses & Benefits

📋 Drug Information

🔬 Pharmacology (PK/PD)

Pharmacokinetics

How It Works

Mechanism Steps

💡 How to Take carvalol 12.5mg tablet

⚠️ Side Effects of carvalol 12.5mg tablet

✅ Common Side Effects

🚨 Serious Side Effects

⚠️ Rare Side Effects

🔬 Drug Interactions

🚨 Major Interactions

⚡ Moderate Interactions

ℹ️ Minor Interactions

🍽️ Food Interactions

🍷 Alcohol Interaction

🛡️ Safety & Warnings

🚫 Contraindications

📊 Monitoring Parameters

🤱 Lactation Safety

💊 Overdose Management

⏰ Missed Dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

🔄 Substitutes for carvalol 12.5mg tablet

⭐ User Reviews

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