carkozom 10 tablet - Carbimazole (10mg) medicine

carkozom 10 tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Care Formulation Labs Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 27, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 27, 2026

What is carkozom 10 tablet used for?

Anti-thyrox 10 Tablet (Carbimazole) is used to treat HORMONES. It contains Carbimazole (10mg), which Inhibits thyroid peroxidase, thereby blocking the synthesis of thyroid hormones.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Carbimazole
  • Manufacturer: Care Formulation Labs Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

๐Ÿ’Š carkozom 10 tablet Uses & Benefits

Hyperthyroidism, Graves' disease, preparation for thyroidectomy, thyrotoxic crisis.

Off-label uses: None commonly reported.

๐Ÿ“‹ Drug Information

Generic Name(s)Carbimazole
Brand NameAnti-thyrox 10 Tablet
ManufacturerCare Formulation Labs Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassHORMONES
Action ClassAntithyroid agents-Thyroid peroxidase inhibitors
Route of AdministrationOral.
StorageStore at room temperature (20-25ยฐC), protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly and completely absorbed from the gastrointestinal tract.
DistributionDistributes widely into body tissues, including thyroid gland.
Protein BindingApproximately 85% bound to plasma proteins.
MetabolismExtensively metabolized in the liver to the active metabolite methimazole.
Half-Life5-6 hours (carbimazole); 4-6 hours (methimazole).
ExcretionPrimarily renal excretion of metabolites.
BioavailabilityApproximately 80-90%.
Onset of Action1-2 weeks for therapeutic effect.
Peak Plasma Time1-2 hours.
Duration of Action24 hours.

How It Works

Inhibits thyroid peroxidase, thereby blocking the synthesis of thyroid hormones.

Mechanism Steps

1Carbimazole is rapidly converted to methimazole in the liver.
2Methimazole inhibits thyroid peroxidase enzyme.
3This prevents iodination of tyrosine residues in thyroglobulin.

๐Ÿ’ก How to Take carkozom 10 tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of carkozom 10 tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Skin rash
  • Pruritus

๐Ÿšจ Serious Side Effects

  • Agranulocytosis
  • Aplastic anemia
  • Hepatotoxicity
  • Hypothyroidism
  • Vasculitis

โš ๏ธ Rare Side Effects

  • Nephritis
  • Lupus-like syndrome
  • Myopathy
  • Polyarteritis nodosa

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased anticoagulant effect due to reduced vitamin K metabolism.
Theophylline Major Increased theophylline clearance.
Digoxin Major Increased digoxin levels due to altered thyroid function.
Beta-blockers Moderate Reduced clearance of beta-blockers.
Oral contraceptives Moderate Reduced contraceptive efficacy.
Phenytoin Moderate Increased phenytoin levels.
Corticosteroids Minor Increased metabolism of corticosteroids.
Insulin Minor Altered insulin requirements.

๐Ÿšจ Major Interactions

  • Warfarin
  • Theophylline
  • Digoxin

โšก Moderate Interactions

  • Beta-blockers
  • Oral contraceptives
  • Phenytoin

โ„น๏ธ Minor Interactions

  • Corticosteroids
  • Insulin

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Avoid excessive alcohol consumption as it may increase hepatotoxicity risk.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to carbimazole or methimazole, severe hepatic impairment, agranulocytosis.

๐Ÿ“Š Monitoring Parameters

Thyroid function tests (T3, T4, TSH), complete blood count (CBC) for agranulocytosis, liver function tests.

๐Ÿคฑ Lactation Safety

Excreted in breast milk; use with caution.

๐Ÿ’Š Overdose Management

Induce vomiting or gastric lavage; administer activated charcoal; monitor for bone marrow suppression.

โฐ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 27, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for carkozom 10 tablet

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Alternative brands with exact same active ingredient (Carbimazole (10mg)):

Medical Note: Always consult your doctor before switching medications.

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