care and clear cream - Hydroquinone (2% w/w) + Mometasone (0.1% w/w) medicine

care and clear cream - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Cosmederma Remedies ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is care and clear cream used for?

Aritop HC Cream (Hydroquinone + Mometasone) is used to treat DERMA. It contains Hydroquinone (2% w/w) + Mometasone (0.1% w/w), which Hydroquinone inhibits tyrosinase, reducing melanin production; Mometasone suppre. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Hydroquinone + Mometasone
  • Manufacturer: Cosmederma Remedies
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

๐Ÿ’Š care and clear cream Uses & Benefits

Melasma, post-inflammatory hyperpigmentation, vitiligo (off-label)

Off-label uses: Vitiligo, Solar lentigines

๐Ÿ“‹ Drug Information

Generic Name(s)Hydroquinone + Mometasone
Brand NameAritop HC Cream
ManufacturerCosmederma Remedies
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassDERMA
Action ClassDepigmenting agent + Corticosteroid
Route of AdministrationTopical
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionTopical absorption; systemic absorption minimal with intact skin
DistributionDistributes locally in skin; minimal systemic distribution
Protein BindingHydroquinone: not extensively bound; Mometasone: 98-99% bound to plasma proteins
MetabolismHydroquinone: hepatic conjugation; Mometasone: hepatic via CYP3A4
Half-LifeHydroquinone: not well defined; Mometasone: 5.8 hours
ExcretionHydroquinone: renal; Mometasone: renal and biliary
BioavailabilityLow systemic bioavailability due to topical application
Onset of ActionWithin 1-2 weeks for depigmentation; anti-inflammatory within days
Peak Plasma TimeNot applicable for topical; systemic peak varies
Duration of ActionDepigmentation: weeks to months; anti-inflammatory: days

How It Works

Hydroquinone inhibits tyrosinase, reducing melanin production; Mometasone suppresses inflammation via glucocorticoid receptor binding

Mechanism Steps

1Hydroquinone inhibits tyrosinase, blocking conversion of tyrosine to melanin
2Mometasone binds to glucocorticoid receptor, inhibiting phospholipase A2 and reducing prostaglandin/leukotriene synthesis
3Reduced melanin production and inflammation lead to skin lightening

๐Ÿ’ก How to Take care and clear cream

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of care and clear cream

โœ… Common Side Effects

  • Skin irritation
  • Dryness
  • Erythema
  • Burning sensation

๐Ÿšจ Serious Side Effects

  • Skin atrophy
  • Telangiectasia
  • Adrenal suppression (prolonged use)

โš ๏ธ Rare Side Effects

  • Allergic contact dermatitis
  • Hypopigmentation
  • Ochronosis (hydroquinone)

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Systemic corticosteroids Major Additive immunosuppression
CYP3A4 inhibitors (e.g., ketoconazole) Moderate Increased systemic mometasone levels
CYP3A4 inducers (e.g., rifampin) Moderate Decreased mometasone efficacy

๐Ÿšจ Major Interactions

  • Corticosteroids (systemic)
  • Immunosuppressants

โšก Moderate Interactions

  • CYP3A4 inhibitors
  • CYP3A4 inducers

โ„น๏ธ Minor Interactions

  • Other topical agents

๐Ÿท Alcohol Interaction

No known interaction

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity, skin infections, open wounds, rosacea, perioral dermatitis

๐Ÿ“Š Monitoring Parameters

Skin response, signs of skin atrophy, hyperpigmentation changes

๐Ÿคฑ Lactation Safety

Caution; avoid application to breast area

๐Ÿ’Š Overdose Management

Discontinue use; symptomatic treatment; unlikely systemic overdose

โฐ Missed Dose

Apply as soon as remembered; skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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