carbolith 400mg tablet

4.5 (11 reviews)

Lithium carbonate (400mg)

🏭 Psycormedies 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is carbolith 400mg tablet used for?

Alkalith 450mg tablet CR (Lithium carbonate) is used to treat NEURO CNS. It contains Lithium carbonate (400mg), which Modulates neurotransmitter release; inhibits inositol monophosphatase; alters G-. Always consult your doctor before use. Take as prescribed.

Generic Name: Lithium carbonate
Manufacturer: Psycormedies
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 carbolith 400mg tablet Uses & Benefits

Bipolar disorder (mania and maintenance), augmentation in depression

Off-label uses: Cluster headaches, neutropenia, hyperthyroidism (rare)

📋 Drug Information

Generic Name(s)	Lithium carbonate
Brand Name	Alkalith 450mg tablet CR
Manufacturer	Psycormedies
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	NEURO CNS
Action Class	Mood stabilizers
Route of Administration	Oral
Storage	Store at room temperature (20-25°C); protect from moisture
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed from GI tract; slow release formulation

DistributionDistributes in total body water; crosses placenta and blood-brain barrier

Protein BindingNot protein bound

MetabolismNot metabolized; excreted unchanged

Half-Life18-24 hours (can vary with age and renal function)

ExcretionRenal (95% unchanged); reabsorbed in proximal tubules

Bioavailability80-100%

Onset of Action1-2 weeks for therapeutic effect

Peak Plasma Time4-12 hours (CR formulation)

Duration of Action24 hours

How It Works

Modulates neurotransmitter release; inhibits inositol monophosphatase; alters G-protein signaling

Mechanism Steps

1Inhibits inositol monophosphatase, reducing IP3 and DAG signaling

2Modulates G-protein coupled receptor signaling

3Alters neurotransmitter release (serotonin, dopamine, glutamate)

💡 How to Take carbolith 400mg tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of carbolith 400mg tablet

✅ Common Side Effects

Nausea
Diarrhea
Tremor
Polyuria
Polydipsia
Weight gain
Fatigue

🚨 Serious Side Effects

Lithium toxicity (ataxia, confusion, seizures)
Arrhythmias
Renal impairment
Hypothyroidism

⚠️ Rare Side Effects

Pseudotumor cerebri
Hyperparathyroidism
Nephrogenic diabetes insipidus
Leukocytosis

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
NSAIDs	Major	Increased lithium levels and toxicity risk
Thiazide diuretics	Major	Increased lithium reabsorption, elevated levels
ACE inhibitors	Major	Decreased lithium excretion, increased toxicity
SSRIs	Moderate	Increased risk of serotonin syndrome
Caffeine	Minor	May decrease lithium levels

🚨 Major Interactions

NSAIDs
ACE inhibitors
Thiazide diuretics
Metronidazole
Carbamazepine

⚡ Moderate Interactions

SSRIs
Verapamil
Methyldopa
Topiramate

ℹ️ Minor Interactions

Caffeine
Theophylline
Sodium bicarbonate

🍽️ Food Interactions

Sodium intake affects lithium levels; avoid low-sodium diets

🍷 Alcohol Interaction

May increase CNS depression; avoid excessive alcohol

🛡️ Safety & Warnings

🚫 Contraindications

Severe renal impairment, severe cardiovascular disease, untreated hypothyroidism, low sodium levels

📊 Monitoring Parameters

Serum lithium levels (therapeutic 0.6-1.2 mEq/L), renal function, thyroid function, ECG

🤱 Lactation Safety

Excreted in breast milk; monitor infant for toxicity

💊 Overdose Management

Gastric lavage, whole bowel irrigation, hemodialysis for severe toxicity; supportive care

⏰ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for carbolith 400mg tablet

View All

Alternative brands with exact same active ingredient (Lithium carbonate (400mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Effective and reliable. Worked as expected.