capxcel tablet - Uses, Price, Side Effects & Substitutes
What is capxcel tablet used for?
bdocin 500mg capsule (Capecitabine) is used to treat ANTI NEOPLASTICS. It contains Capecitabine (500mg), which Prodrug converted to 5-FU, which inhibits thymidylate synthase and incorporates . Always consult your doctor before use. Take as prescribed.
- Generic Name: Capecitabine
- Manufacturer: Khandelwal Laboratories Pvt Ltd
- Form: Allopathy
- Pregnancy Category: D
- Prescription Required: Yes
๐ capxcel tablet Uses & Benefits
Colorectal cancer, breast cancer, gastric cancer, esophageal cancer
Off-label uses: Pancreatic cancer, hepatocellular carcinoma
๐ Drug Information
| Generic Name(s) | Capecitabine |
| Brand Name | bdocin 500mg capsule |
| Manufacturer | Khandelwal Laboratories Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI NEOPLASTICS |
| Action Class | Antimetabolites |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Prodrug converted to 5-FU, which inhibits thymidylate synthase and incorporates into RNA/DNA
Mechanism Steps
๐ก How to Take capxcel tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of capxcel tablet
โ Common Side Effects
- Diarrhea
- Hand-foot syndrome
- Nausea
- Vomiting
- Fatigue
- Anorexia
- Abdominal pain
- Stomatitis
๐จ Serious Side Effects
- Myelosuppression
- Severe diarrhea
- Cardiotoxicity
- Hepatotoxicity
- Neurotoxicity
- Dehydration
โ ๏ธ Rare Side Effects
- Encephalopathy
- Cerebellar ataxia
- Keratitis
- Lacrimal duct stenosis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased INR and bleeding risk |
| Phenytoin | Major | Increased phenytoin levels |
| Leucovorin | Major | Increased toxicity of 5-FU |
| Sorivudine | Major | Fatal toxicity due to DPD inhibition |
| Brivudine | Major | Fatal toxicity due to DPD inhibition |
| Allopurinol | Moderate | Decreased efficacy of capecitabine |
| Metronidazole | Moderate | Increased 5-FU toxicity |
| Cimetidine | Moderate | Increased capecitabine levels |
| Folic acid | Moderate | Increased toxicity |
| Antacids | Minor | Decreased absorption |
| Ranitidine | Minor | Decreased absorption |
๐จ Major Interactions
- Warfarin
- Phenytoin
- Leucovorin
- Sorivudine
- Brivudine
โก Moderate Interactions
- Allopurinol
- Metronidazole
- Cimetidine
- Folic acid
โน๏ธ Minor Interactions
- Antacids
- Ranitidine
๐ฝ๏ธ Food Interactions
Food reduces rate and extent of absorption; take with food or within 30 min after meal
๐ท Alcohol Interaction
Avoid alcohol; may increase hepatotoxicity risk
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Severe renal impairment (CrCl <30 mL/min), DPD deficiency, hypersensitivity, pregnancy, lactation
๐ Monitoring Parameters
CBC, LFTs, renal function, INR (if on warfarin), DPD deficiency screening
๐คฑ Lactation Safety
Contraindicated; excreted in milk
๐ Overdose Management
Supportive care; no specific antidote; monitor for myelosuppression, GI toxicity
โฐ Missed Dose
Do not double dose; skip missed dose and continue regular schedule
๐จโโ๏ธ Reviewed by Expert
๐ Substitutes for capxcel tablet
View AllAlternative brands with exact same active ingredient (Capecitabine (500mg)):
-
capcita 500mg tabletWockhardt Ltd โน81.25 94.4% CHEAPER
-
capad 500mg tabletOncocare Scientifics Pvt Ltd โน83.44 94.3% CHEAPER
-
caxeta 500mg tabletSun Pharmaceutical Industries Ltd โน481.61 67% CHEAPER
-
distamine 500mg tabletNeon Laboratories Ltd โน706.00 51.7% CHEAPER
-
capegard 500 tabletCipla Ltd โน854.00 41.5% CHEAPER
-
capecad 500mg tabletCadila Pharmaceuticals Ltd โน952.37 34.8% CHEAPER
-
zenocite 500mg tabletUnimark Remedies Ltd โน1,047.22 28.3% CHEAPER
-
capecite 500mg tabletAbbott โน1,134.72 22.3% CHEAPER
-
captain 500mg tabletFeron Healthcare Pvt Ltd โน1,148.44 21.4% CHEAPER
-
cabita 500mg tabletGetwell Oncology Pvt Ltd โน1,171.88 19.8% CHEAPER
Medical Note: Always consult your doctor before switching medications.