caplanz plus 20mg/10mg tablet - Uses, Price, Side Effects & Substitutes
What is caplanz plus 20mg/10mg tablet used for?
Concern F 20 mg/5 mg Tablet (Fluoxetine + Olanzapine) is used to treat NEURO CNS. It contains Fluoxetine (20mg) + Olanzapine (10mg), which Fluoxetine selectively inhibits serotonin reuptake; Olanzapine antagonizes dopam. Always consult your doctor before use. Take as prescribed.
- Generic Name: Fluoxetine + Olanzapine
- Manufacturer: Sycap Pharma
- Form: Allopathy
- Pregnancy Category: C
- Prescription Required: Yes
๐ caplanz plus 20mg/10mg tablet Uses & Benefits
Major depressive disorder with psychotic features, bipolar depression, treatment-resistant depression.
Off-label uses: Anxiety disorders, OCD, PTSD, Bulimia nervosa
๐ Drug Information
| Generic Name(s) | Fluoxetine + Olanzapine |
| Brand Name | Concern F 20 mg/5 mg Tablet |
| Manufacturer | Sycap Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Antidepressant + Antipsychotic |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC (68-77ยฐF); protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Fluoxetine selectively inhibits serotonin reuptake; Olanzapine antagonizes dopamine D2 and serotonin 5-HT2A receptors.
Mechanism Steps
๐ก How to Take caplanz plus 20mg/10mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of caplanz plus 20mg/10mg tablet
โ Common Side Effects
- Weight gain
- Somnolence
- Dry mouth
- Constipation
- Dizziness
- Fatigue
- Increased appetite
๐จ Serious Side Effects
- Serotonin syndrome
- Neuroleptic malignant syndrome
- QT prolongation
- Seizures
- Suicidal thoughts
- Pancreatitis
โ ๏ธ Rare Side Effects
- Priapism
- Hepatotoxicity
- Agranulocytosis
- Tardive dyskinesia
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Serotonin syndrome risk |
| Thioridazine | Major | QT prolongation |
| Pimozide | Major | QT prolongation |
| Linezolid | Major | Serotonin syndrome |
| Methylene Blue | Major | Serotonin syndrome |
| Warfarin | Moderate | Increased bleeding risk |
| NSAIDs | Moderate | Increased bleeding risk |
| Benzodiazepines | Moderate | Increased sedation |
| CYP1A2 inhibitors | Moderate | Increased olanzapine levels |
| CYP2D6 substrates | Moderate | Increased levels of other drugs |
| Cimetidine | Minor | Increased fluoxetine levels |
| Carbamazepine | Minor | Decreased olanzapine levels |
| Lithium | Minor | Increased lithium levels |
๐จ Major Interactions
- MAOIs
- Thioridazine
- Pimozide
- Linezolid
- Methylene Blue
โก Moderate Interactions
- CYP2D6 substrates
- CYP1A2 inhibitors
- NSAIDs
- Anticoagulants
- Benzodiazepines
โน๏ธ Minor Interactions
- Cimetidine
- Carbamazepine
- Lithium
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase olanzapine levels, High-fat meal delays absorption
๐ท Alcohol Interaction
Avoid; increased CNS depression and hepatotoxicity risk.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, MAOI use within 14 days, narrow-angle glaucoma, severe CNS depression.
๐ Monitoring Parameters
Weight, blood glucose, lipid profile, LFTs, ECG, suicidal ideation, extrapyramidal symptoms.
๐คฑ Lactation Safety
Not recommended; excreted in breast milk.
๐ Overdose Management
Activated charcoal, supportive care; no specific antidote.
โฐ Missed Dose
Take as soon as remembered unless near next dose; skip if close.