canace-th od tablet sr - Aceclofenac (200mg) + Thiocolchicoside (8mg) medicine

Arflur LBP 200 mg/8 mg Capsule: Comprehensive Medicine Guide

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🏭 Maverick Pharma Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 24, 2026
⚠️ Hepatotoxicity Risk ⚠️ Nephrotoxicity Risk 🤰 Pregnancy Category Not established from the available information. However, NSAIDs like aceclofenac are generally avoided during pregnancy, especially in the third trimester, due to risks of premature closure of ductus arteriosus and kidney problems in the fetus. Thiocolchicoside is also not recommended during pregnancy. Consult your doctor for safer alternatives. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for short-term use in acute musculoskeletal pain with spasm.
Reviewed by
SaathiMed Expert Panel | Sep 24, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Unusual bleeding or bruising
  • Severe skin rash or blistering

If experiencing severe symptoms, call emergency services immediately.

What is canace-th od tablet sr used for?

This medicine is a combination of Aceclofenac 200 mg and Thiocolchicoside 8 mg used for short-term relief of acute musculoskeletal pain and muscle spasm. It works by reducing inflammation and relaxing muscles. It should be taken with food, usually twice daily, and must be prescribed by a doctor.

  • Generic Name: Aceclofenac + Thiocolchicoside
  • Manufacturer: Maverick Pharma Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 canace-th od tablet sr के बारे में (Hindi Summary)

उपयोग: यह दवा एसिफ्लोफेनाक 200 मिलीग्राम और थायोकोल्चिकोसाइड 8 मिलीग्राम का संयोजन है। इसका उपयोग मांसपेशियों में ऐंठन और दर्द के इलाज के लिए किया जाता है, जैसे कमर दर्द, गर्दन दर्द, चोट या सर्जरी के बाद होने वाला दर्द। यह सूजन को कम करने और मांसपेशियों को आराम देने में मदद करती है। इसे डॉक्टर के परामर्श के बिना नहीं लेना चाहिए।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी, पेट दर्द, अपच, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन पेट में रक्तस्राव, एलर्जी, गुर्दे या यकृत की समस्या हो सकती है। यदि मल में खून आए, उल्टी में खून आए, त्वचा या आंखें पीली हों, या पेशाब कम आए, तो तुरंत डॉक्टर से मिलें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। यदि आपको चक्कर आते हैं या नींद आती है, तो वाहन न चलाएं। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। बिना डॉक्टर की सलाह के अन्य दर्द निवारक दवाएं न लें।

💡 Did You Know? The Indian pharmaceutical market is expected to reach $130 billion by 2030.

💊 canace-th od tablet sr Uses & Benefits

[{"condition":"Acute low back pain with muscle spasm","description":"This medicine helps reduce pain and inflammation while relieving muscle spasm, improving mobility.","evidence":"Well-established"},{"condition":"Neck pain (cervical spondylosis) with muscle spasm","description":"It provides symptomatic relief from pain and stiffness associated with cervical muscle spasm.","evidence":"Moderate"},{"condition":"Post-traumatic pain and swelling","description":"Used after injuries like sprains or strains to reduce pain, swelling, and muscle spasm.","evidence":"Moderate"},{"condition":"Post-operative pain and muscle spasm","description":"May be prescribed short-term after surgery to manage pain and spasm.","evidence":"Limited"},{"condition":"Osteoarthritis flare-up","description":"Can be used short-term for painful osteoarthritis exacerbations with muscle spasm.","evidence":"Limited"}]

Off-label uses: [{"condition":"Tension-type headache","description":"Sometimes prescribed off-label for tension headaches with muscle tightness.","evidence":"Limited"},{"condition":"Fibromyalgia pain","description":"Rarely used off-label for short-term relief of fibromyalgia pain and spasm.","evidence":"Limited"}]

Primary treatment for: Acute musculoskeletal pain with muscle spasm

Also treats: Low back pain, Neck pain, Post-traumatic pain, Post-operative pain, Osteoarthritis flare-up

📋 Drug Information

Generic Name(s)Aceclofenac + Thiocolchicoside
Brand NameAldigesic TH 100mg/4mg Tablet
ManufacturerMaverick Pharma Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassNSAID + Muscle Relaxant
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep in the original container.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Always take this medicine with food to reduce the risk of stomach upset.
2
Do not exceed the prescribed dose or duration without consulting your doctor.
3
Avoid alcohol completely while taking this medicine to prevent stomach bleeding.
4
If you experience drowsiness or dizziness, avoid driving or operating heavy machinery.
5
Inform your doctor if you have a history of stomach ulcers, kidney, liver, or heart disease.
6
Do not take other pain relievers or NSAIDs without your doctor's approval.
7
If symptoms persist beyond 7 days, consult your doctor for re-evaluation.
8
Report any unusual bleeding, bruising, or yellowing of eyes to your doctor immediately.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Chronic joint pain
This medicine is commonly prescribed for this.
Likely Use
❌
Fever
This medicine is not a primary fever reducer.
Not Primary
✅
Muscle spasm
Thiocolchicoside component helps relieve muscle spasm.
Likely Use
❌
Headache
Not typically used for primary headache.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAceclofenac is rapidly absorbed after oral administration. Thiocolchicoside is also well absorbed from the gastrointestinal tract. Food may slightly delay absorption but does not significantly affect the extent of absorption.
DistributionAceclofenac is highly protein-bound and distributes into synovial fluid. Thiocolchicoside distributes widely into tissues, including muscle and central nervous system.
Protein BindingAceclofenac: >99% bound to plasma proteins. Thiocolchicoside: Approximately 80% bound to plasma proteins.
MetabolismAceclofenac is metabolized in the liver primarily by CYP2C9 to inactive metabolites. Thiocolchicoside is metabolized in the liver by glucuronidation and sulfation.
Half-LifeAceclofenac: Approximately 4-6 hours. Thiocolchicoside: Approximately 4-6 hours.
ExcretionAceclofenac metabolites are excreted mainly in urine and bile. Thiocolchicoside is excreted primarily in urine as metabolites.
BioavailabilityAceclofenac: Approximately 80-90%. Thiocolchicoside: Approximately 70-80%.
Onset of ActionPain relief typically begins within 30-60 minutes after oral administration.
Peak Plasma TimeAceclofenac: 1.5-3 hours. Thiocolchicoside: 1-2 hours.
Duration of ActionPain relief lasts approximately 6-8 hours, requiring twice-daily dosing.

How It Works

This medicine combines two active ingredients with complementary mechanisms. Aceclofenac is a non-steroidal anti-inflammatory drug that inhibits cyclooxygenase (COX) enzymes, leading to decreased production of prostaglandins, which are mediators of pain and inflammation. Thiocolchicoside is a centrally acting muscle relaxant that acts as a GABA-A receptor agonist, enhancing inhibitory neurotransmission in the spinal cord and brain, thereby reducing muscle spasm and stiffness. Together, they provide both anti-inflammatory and muscle relaxant effects.

Mechanism Steps

1
Aceclofenac inhibits COX enzymes: Aceclofenac blocks cyclooxygenase enzymes, reducing prostaglandin synthesis and thereby decreasing inflammation and pain.
2
Thiocolchicoside activates GABA-A receptors: Thiocolchicoside binds to GABA-A receptors in the central nervous system, enhancing inhibitory signals that reduce muscle spasm.
3
Combined effect: The anti-inflammatory action of aceclofenac and the muscle relaxant action of thiocolchicoside work together to relieve pain and spasm.

💡 How to Take canace-th od tablet sr

Strength: Each capsule contains Aceclofenac 200 mg and Thiocolchicoside 8 mg.

1Swallow the capsule whole with a glass of water.
2Take it with food or milk to reduce stomach upset.
3Do not crush, chew, or open the capsule.
4Take at the same times each day to maintain consistent levels.
5If you miss a dose, follow the missed dose instructions.
6Do not take more than the prescribed dose.

Dosage Information

Adult DosageThe usual adult dose is one capsule taken orally twice daily, preferably with food. However, the exact dose and duration must be individualized by a qualified clinician based on the indication, severity of symptoms, age, weight, renal and hepatic function, and response to treatment. Do not self-adjust the dose. Do not exceed the recommended dose or duration.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients (above 65 years) may be more sensitive to the effects of this medicine, especially gastrointestinal, renal, and cardiovascular side effects. Use with caution, at the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly.
Renal ImpairmentUse with caution in patients with mild to moderate renal impairment. Dose adjustment may be necessary. Avoid in severe renal impairment (eGFR <30 mL/min). Consult a doctor for individualized dosing.
Hepatic ImpairmentUse with caution in patients with mild to moderate hepatic impairment. Dose adjustment may be necessary. Avoid in severe hepatic impairment. Consult a doctor for individualized dosing.
Maximum Daily DoseThe maximum recommended daily dose is one capsule twice daily (i.e., aceclofenac 400 mg and thiocolchicoside 16 mg per day). Do not exceed this dose.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Alcohol
Avoid
Increases risk of gastrointestinal bleeding and liver toxicity.
Grapefruit juice
Avoid or limit
May increase drug levels by affecting liver enzymes.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of canace-th od tablet sr

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food. If persistent, consult your doctor.
Stomach pain or indigestion (Common (5-10%))
Take with food or milk. Avoid spicy foods. Consult doctor if severe.
Headache (Common (5-10%))
Usually resolves. Stay hydrated. Consult doctor if persistent.
Dizziness or drowsiness (Common (5-10%))
Avoid driving or operating machinery until you know how it affects you.
Diarrhea or constipation (Common (5-10%))
Maintain hydration. Consult doctor if severe or persistent.

🚨 Serious Side Effects

Gastrointestinal bleeding or ulceration (Rare (<0.1%))
Seek immediate medical attention if you notice black or tarry stools, vomiting blood, or severe abdominal pain.
Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Call emergency services if you experience swelling of face, lips, throat, difficulty breathing, or severe rash.
Kidney impairment (Rare (<0.1%))
Report decreased urine output, swelling in legs, or fatigue to your doctor immediately.
Liver damage (Rare (<0.1%))
Seek medical attention if you notice yellowing of eyes or skin, dark urine, or severe fatigue.
Blood disorders (e.g., agranulocytosis, thrombocytopenia) (Very rare (<0.01%))
Report unusual bleeding, bruising, fever, or sore throat to your doctor promptly.

⚠️ Rare Side Effects

Photosensitivity reactions
Avoid excessive sun exposure. Use sunscreen. Consult doctor if rash occurs.
Mood changes or confusion
Consult your doctor if you experience unusual mood changes or confusion.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Ibuprofen Major
Corticosteroids Major
Methotrexate Major
Lithium Major
ACE inhibitors Moderate
SSRIs Moderate
Cyclosporine Moderate
Digoxin Moderate
Antacids Minor

🚨 Major Interactions

  • Warfarin and other anticoagulants
  • Other NSAIDs (e.g., ibuprofen, naproxen)
  • Corticosteroids
  • Methotrexate
  • Lithium

⚡ Moderate Interactions

  • Antihypertensives (e.g., ACE inhibitors, ARBs, diuretics)
  • SSRIs
  • Cyclosporine
  • Digoxin

🍷 Alcohol Interaction

Avoid alcohol while taking this medicine. Alcohol increases the risk of gastrointestinal bleeding, ulceration, and liver damage. It may also worsen drowsiness and dizziness.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to aceclofenac, thiocolchicoside, or any component","History of asthma, urticaria, or allergic reactions to NSAIDs","Active or history of peptic ulcer or gastrointestinal bleeding","Severe heart failure","Severe kidney impairment (eGFR

⚠️ Warnings & Precautions

["Take with food to minimize stomach upset.","Avoid alcohol consumption.","Do not drive or operate machinery if you feel dizzy or drowsy.","Use with caution in elderly patients due to increased risk of side effects.","Monitor for signs of gastrointestinal bleeding.","Inform your doctor if you have a history of kidney or liver disease.","Do not use for longer than prescribed without medical advice.","Avoid in patients with cardiovascular risk factors unless clearly needed.","Do not take other pain relievers without consulting your doctor.","Keep out of reach of children."]

🤱 Lactation Safety

Not established from the available information. It is not known whether aceclofenac and thiocolchicoside pass into breast milk. Due to potential risks to the infant, this medicine is generally not recommended during breastfeeding. Consult your doctor for alternative treatments.

💊 Overdose Management

Overdose may cause severe nausea, vomiting, abdominal pain, gastrointestinal bleeding, drowsiness, and kidney or liver damage. If you suspect an overdose, seek immediate medical attention. Treatment is supportive and symptomatic. There is no specific antidote. Gastric lavage may be considered if taken recently. Monitor vital signs, renal and hepatic function, and manage complications.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as prescribed by your doctor. Do not exceed the recommended dose or duration. Always take it with food or milk to reduce stomach irritation. Avoid alcohol while taking this medicine, as it can increase the risk of stomach bleeding and liver problems. Do not drive or operate heavy machinery if you feel dizzy or drowsy. Inform your doctor if you have a history of stomach ulcers, kidney or liver disease, heart problems, or asthma. Do not take other pain relievers or NSAIDs without consulting your doctor. If you are pregnant, planning pregnancy, or breastfeeding, consult your doctor before taking this medicine. Keep out of reach of children. Store at room temperature away from moisture and sunlight. Do not use after the expiry date.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of gastrointestinal bleeding, kidney impairment, and cardiovascular side effects. Use the lowest effective dose for the shortest duration. Monitor renal and hepatic function regularly. Avoid in frail elderly with multiple comorbidities.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended during pregnancy or when planning pregnancy. NSAIDs like aceclofenac may affect ovulation and increase the risk of miscarriage. Consult your doctor for safer alternatives if you are trying to conceive.

🏥 Post-Surgery Considerations

This medicine may be prescribed after surgery for short-term pain and muscle spasm relief. However, it may increase bleeding risk and interfere with bone healing. Use only under medical supervision. Inform your surgeon if you are taking this medicine before any surgery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure, as it may increase bleeding risk. Your dentist may advise stopping it temporarily before surgery.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy weight to reduce joint stress.
🥗
Regular low-impact exercise like swimming or walking.
😴
Practice good posture while sitting and standing.
💧
Include anti-inflammatory foods like omega-3 rich fish, fruits, and vegetables.
🧘
Get adequate sleep to aid recovery.
🌞
Apply heat or cold packs to affected areas as advised.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while taking this medicine, especially if you have muscle spasm or pain. Gentle stretching and low-impact activities may be beneficial, but consult your doctor or physiotherapist before starting any exercise program.

🥗 Diet Recommendations

Include omega-3 rich foods like salmon, flaxseeds, and walnuts.
Reduce processed and fried food intake.
Stay well hydrated by drinking plenty of water.
Eat a balanced diet rich in fruits and vegetables.
Limit caffeine and alcohol.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It may also cause stomach upset, so take it with food. Inform your employer if your job involves operating machinery.

🛑 When to Stop This Medicine

Stop taking this medicine if you experience severe side effects such as gastrointestinal bleeding, allergic reactions, or kidney problems. Do not stop abruptly if you have been taking it for a long time without consulting your doctor. Usually, it is prescribed for short-term use, and your doctor will advise when to stop.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of gastrointestinal bleeding, kidney impairment, liver damage, and cardiovascular events. It is intended for short-term use only. Regular monitoring of kidney and liver function, blood pressure, and complete blood count is advised if prolonged use is necessary. Consult your doctor for alternative treatments if pain persists.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Physical therapy

Can complement medicine for chronic pain and improve muscle strength.

Evidence: Well-established
Hot/cold therapy

Applying heat or cold packs can help relieve muscle spasm and pain.

Evidence: Moderate
Acupuncture

May provide pain relief for some individuals.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

Not established from the available information. There are no known interactions between this medicine and vaccines. However, consult your doctor before receiving any vaccine while on this medicine.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

Carry this medicine in its original packaging with a copy of your prescription. Store at room temperature, away from direct sunlight and moisture. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Keep it in your carry-on luggage. Check customs regulations for prescription medicines in your destination country.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with chronic knee pain
Started this medicine as prescribed for osteoarthritis. Within 2 weeks noticed significant improvement in morning stiffness. Emphasized taking with food to prevent stomach upset.
💡 Lesson: Consistency with prescribed dose and taking with food improves both efficacy and tolerability.
👤 A 35-year-old athlete with acute lower back strain
After a sports injury, he was prescribed this medicine. He took it with meals and avoided alcohol. Pain and spasm improved within 3 days, allowing him to return to light activity.
💡 Lesson: Short-term use with proper precautions can effectively manage acute musculoskeletal pain.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: Pain relief typically begins within 30-60 minutes after taking the capsule.

Q: Can I take it on an empty stomach?

A: It is best taken with food to reduce stomach upset.

Q: Is it safe to take with other painkillers?

A: Do not take other NSAIDs or painkillers without consulting your doctor, as it may increase the risk of side effects.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for canace-th od tablet sr

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine is a steroid.
    Fact: No, it contains an NSAID (aceclofenac) and a muscle relaxant (thiocolchicoside). It is not a steroid.
  • Myth: This medicine can be taken for any type of pain.
    Fact: It is specifically for musculoskeletal pain with muscle spasm. It is not for all types of pain.
  • Myth: It is safe to take this medicine without a prescription.
    Fact: It is a prescription medicine and should only be taken under medical supervision.
  • Myth: This medicine can be taken long-term for chronic pain.
    Fact: It is intended for short-term use. Long-term use requires medical evaluation and monitoring.

🔄 Alternative Options

Generic Alternatives

  • Aceclofenac 200 mg + Thiocolchicoside 8 mg capsule (generic)

Brand Alternatives

  • Arflur LBP 200 mg/8 mg capsule

📊 Comparison with Similar Medicines

[{"medicine":"This medicine","composition":"Aceclofenac 200 mg + Thiocolchicoside 8 mg","uses":"Acute musculoskeletal pain with spasm","notes":"Higher strength of aceclofenac and thiocolchicoside."},{"medicine":"Aceclofenac 100 mg + Thiocolchicoside 4 mg","composition":"Aceclofenac 100 mg + Thiocolchicoside 4 mg","uses":"Acute musculoskeletal pain with spasm","notes":"Lower strength, may be used in milder cases or for dose titration."},{"medicine":"Diclofenac 50 mg + Thiocolchicoside 4 mg","composition":"Diclofenac 50 mg + Thiocolchicoside 4 mg","uses":"Acute musculoskeletal pain with spasm","notes":"Different NSAID; may have different side effect profile."}]

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