Axogurd-SR Tablet: Comprehensive Guide to Uses, Side Effects, and Safety
When to Call Your Doctor IMMEDIATELY
- Swelling of face, lips, throat, or tongue
- Difficulty breathing or swallowing
- Suicidal thoughts or self-harm
- Severe dizziness or fainting
- Chest pain or irregular heartbeat
- Sudden weight gain or swelling in legs
- Yellowing of skin or eyes
- Decreased urine output
- Unusual muscle pain or weakness
- Severe abdominal pain
If experiencing severe symptoms, call emergency services immediately.
What is camnerv p 1500mcg/75mg tablet used for?
This medicine is a combination of Methylcobalamin (1500 mcg) and Pregabalin (75 mg) used to treat neuropathic pain, including diabetic neuropathy and postherpetic neuralgia. It works by reducing abnormal nerve signals and supporting nerve health. Take it exactly as prescribed, and avoid alcohol and driving until you know how it affects you.
- Generic Name: Methylcobalamin + Pregabalin
- Manufacturer: Kameo Pharma Products Private Limited
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 camnerv p 1500mcg/75mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा मेथिलकोबालामिन और प्रीगाबालिन का संयोजन है, जिसका उपयोग न्यूरोपैथिक दर्द, जैसे डायबिटिक न्यूरोपैथी और पोस्टहर्पेटिक न्यूराल्जिया के इलाज के लिए किया जाता है। यह तंत्रिका दर्द को कम करने और तंत्रिका स्वास्थ्य का समर्थन करने में मदद करती है।
साइड इफेक्ट्स: आम दुष्प्रभावों में चक्कर आना, नींद आना, थकान, धुंधली दृष्टि, मुँह सूखना और पैरों में सूजन शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एंजियोएडेमा, आत्महत्या के विचार, और गंभीर एलर्जी प्रतिक्रियाएँ हो सकती हैं। किसी भी असामान्य लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के निर्देशानुसार ही लें। शराब से बचें क्योंकि इससे नींद और चक्कर बढ़ सकते हैं। जब तक आपको पता न चले कि यह दवा आप पर कैसे असर करती है, वाहन न चलाएँ। गुर्दे की समस्या, हृदय विफलता, या नशीली दवाओं के दुरुपयोग के इतिहास के बारे में अपने डॉक्टर को बताएं। इस दवा को अचानक बंद न करें।
💊 camnerv p 1500mcg/75mg tablet Uses & Benefits
[{"condition":"Diabetic peripheral neuropathy","description":"Relieves burning, tingling, and shooting pain in the feet and hands caused by nerve damage from diabetes.","evidence":"Well-established"},{"condition":"Postherpetic neuralgia","description":"Reduces persistent nerve pain following a shingles infection.","evidence":"Well-established"},{"condition":"Neuropathic pain","description":"Used for various neuropathic pain syndromes, including spinal cord injury pain and phantom limb pain.","evidence":"Moderate"},{"condition":"Vitamin B12 deficiency with neurological symptoms","description":"Methylcobalamin component helps correct B12 deficiency and supports nerve regeneration.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Fibromyalgia","description":"Sometimes prescribed off-label to reduce widespread musculoskeletal pain and improve sleep.","evidence":"Limited"},{"condition":"Generalized anxiety disorder","description":"Pregabalin has been studied off-label for anxiety, but is not first-line.","evidence":"Limited"},{"condition":"Chronic low back pain with neuropathic component","description":"May be used off-label when nerve involvement is suspected.","evidence":"Limited"}]
Primary treatment for: Diabetic peripheral neuropathy
Also treats: Postherpetic neuralgia, Neuropathic pain, Vitamin B12 deficiency with neurological symptoms
📋 Drug Information
| Generic Name(s) | Methylcobalamin + Pregabalin |
| Brand Name | Axogurd-SR Tablet |
| Manufacturer | Kameo Pharma Products Private Limited |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Neurotropic vitamin + Gabapentinoid |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a dry place, away from direct sunlight and moisture. Keep out of reach of children. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients. Methylcobalamin acts as a coenzyme for methionine synthase, supporting methylation reactions essential for myelin synthesis and nerve cell maintenance. Pregabalin binds to the alpha-2-delta subunit of voltage-gated calcium channels in the central nervous system, reducing calcium influx and subsequently decreasing the release of excitatory neurotransmitters such as glutamate, norepinephrine, and substance P. This leads to reduced neuronal excitability and analgesic effects. Together, they address both the nutritional and the neuropathic components of nerve pain.
Mechanism Steps
💡 How to Take camnerv p 1500mcg/75mg tablet
Strength: Tablet containing Methylcobalamin 1500 mcg and Pregabalin 75 mg.
Dosage Information
| Adult Dosage | The usual adult dose is one tablet taken orally once or twice daily, or as directed by your physician. The dose may be adjusted based on your condition, response to treatment, and renal function. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may require dose reduction due to decreased renal function. Start with a lower dose and titrate slowly. Monitor for side effects such as dizziness and drowsiness. |
| Renal Impairment | Pregabalin dose should be adjusted in patients with renal impairment. For creatinine clearance 30-60 mL/min, reduce dose by 50%. For creatinine clearance 15-30 mL/min, reduce dose by 75%. For creatinine clearance <15 mL/min, use 25% of the normal dose. Methylcobalamin dose adjustment not required. |
| Hepatic Impairment | No specific dose adjustment recommended for hepatic impairment. However, use with caution and monitor liver function. |
| Maximum Daily Dose | The maximum recommended daily dose of Pregabalin is 600 mg. For this combination, the maximum daily dose is typically 150 mg Pregabalin (two tablets) unless otherwise directed by a physician. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of camnerv p 1500mcg/75mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Opioids | Major | |
| Benzodiazepines | Major | |
| ACE inhibitors | Major | |
| Thiazolidinediones | Moderate | |
| Loop diuretics | Moderate |
🚨 Major Interactions
- CNS depressants (e.g., opioids, benzodiazepines, alcohol)
- Angiotensin-converting enzyme (ACE) inhibitors
⚡ Moderate Interactions
- Thiazolidinediones (e.g., pioglitazone)
- Loop diuretics
🍷 Alcohol Interaction
Avoid alcohol while taking this medicine. Alcohol can increase the risk of dizziness, drowsiness, and other central nervous system side effects. It may also worsen nerve pain.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to Methylcobalamin, Pregabalin, or any component of the formulation","Concurrent use with strong CNS depressants (relative)"]
⚠️ Warnings & Precautions
["May cause dizziness and drowsiness; avoid driving or operating machinery until effects are known.","May cause peripheral edema and heart failure; use with caution in patients with cardiovascular disease.","May increase suicidal thoughts; monitor mood closely.","May cause angioedema; discontinue immediately if swelling occurs.","Do not stop abruptly; taper gradually to avoid withdrawal symptoms.","Use with caution in renal impairment; dose adjustment may be needed.","Not recommended during pregnancy unless clearly needed.","Not recommended during breastfeeding."]
🤱 Lactation Safety
Pregabalin is excreted in breast milk. Breastfeeding is not recommended during treatment. Methylcobalamin is considered safe during breastfeeding.
💊 Overdose Management
Overdose may cause excessive drowsiness, dizziness, and confusion. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Hemodialysis may be considered for pregabalin overdose.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
Additional Safety Advice
Take this medicine exactly as prescribed. Do not exceed the recommended dose. Avoid alcohol as it can increase drowsiness and dizziness. Do not drive or operate machinery until you know how this medicine affects you. Inform your doctor if you have kidney problems, heart failure, or a history of substance abuse. Do not stop taking this medicine abruptly without consulting your doctor, as withdrawal symptoms may occur. Keep out of reach of children. Store at room temperature away from moisture and heat. If you are pregnant or planning to become pregnant, consult your doctor before taking this medicine.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to experience dizziness, drowsiness, and peripheral edema. Dose reduction may be necessary due to age-related decline in renal function. Monitor closely for falls and cognitive effects.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. Pregabalin may harm the fetus. Effective contraception should be used during treatment. Discuss alternative treatments if you are pregnant or planning pregnancy.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist that you are taking this medicine. It may interact with anesthetic agents and increase the risk of respiratory depression. Your dose may need to be adjusted before surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine. It may interact with local anesthetics or sedatives used during dental procedures. Your dentist may need to adjust the treatment plan.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid high-impact exercises that may worsen nerve pain. Consult your doctor before starting any new exercise regimen. If you experience dizziness or drowsiness, avoid activities that require balance or coordination.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness and drowsiness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It may also cause blurred vision; use caution when reading or using screens. Inform your employer if your job requires alertness.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience serious side effects or your condition improves, your doctor may gradually reduce the dose. Abrupt discontinuation can cause withdrawal symptoms.
📅 Long-Term Use Effects
Long-term use of this medicine may require periodic monitoring of renal function, vitamin B12 levels, and neurological status. Pregabalin has a potential for dependence and withdrawal symptoms. Methylcobalamin is generally safe for long-term use. Regular follow-up with your doctor is essential to assess the continued need and adjust the dose.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Can help improve strength and reduce nerve pain.
Evidence: Well-establishedMay provide relief for some patients with neuropathic pain.
Evidence: LimitedMay help reduce pain signals.
Evidence: Moderate💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific vaccine interactions are known. However, inform your healthcare provider about this medicine before receiving any vaccine.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with a copy of your prescription. Keep it in your carry-on luggage to avoid loss. Store at room temperature and protect from extreme heat or cold. If crossing time zones, adjust dosing times gradually to maintain consistent intervals. Check local customs regulations for controlled substances, as Pregabalin may be regulated in some countries.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel some relief within a few days, but it may take 2-4 weeks for the full effect. Continue taking it as prescribed.
A: No, alcohol can increase drowsiness and dizziness and may worsen your condition. Avoid alcohol completely.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Pregabalin should be used during pregnancy only if the potential benefit justifies the potential risk. Consult your doctor if you are pregnant or planning to become pregnant.
A: No, stopping abruptly can cause withdrawal symptoms such as insomnia, headache, nausea, and anxiety. Always consult your doctor before stopping.
🤔 Common Patient Concerns
🔄 Substitutes for camnerv p 1500mcg/75mg tablet
View AllAlternative brands with exact same active ingredient:
-
davaindia methylcobalamin+pregabalin 1500mcg/75mg tablet srDavaindia Generic Pharmacy ₹50.00 68.1% CHEAPER
-
nervigesic pg 1500mcg/75mg tabletIndian Pharmaceuticals ₹65.53 58.2% CHEAPER
-
aconerv-p tablet srAcmedix Pharma LLP ₹67.50 56.9% CHEAPER
-
binerve 1500 tablet srFreedom Healthcare Pvt Ltd ₹79.69 49.1% CHEAPER
-
nurotek-pg tablet srMacsys LifeSciences ₹79.69 49.1% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine is a painkiller like ibuprofen.
Fact: This medicine is not a typical painkiller; it specifically targets nerve pain and does not work for ordinary muscle or joint pain. - Myth: You can stop taking this medicine whenever you feel better.
Fact: Stopping abruptly can cause withdrawal symptoms. Always consult your doctor before stopping. - Myth: This medicine is safe to take with alcohol.
Fact: Alcohol increases the risk of drowsiness, dizziness, and other side effects. Avoid alcohol. - Myth: This medicine will cure nerve damage.
Fact: It helps manage symptoms and may support nerve health, but it does not cure the underlying cause.
🔄 Alternative Options
Generic Alternatives
- Methylcobalamin + Pregabalin (generic)
Brand Alternatives
- Axogurd-SR Tablet
- Pregabalin + Methylcobalamin combinations