calmwin plus 0.5mg/10mg tablet - Uses, Price, Side Effects & Substitutes
What is calmwin plus 0.5mg/10mg tablet used for?
Asiclopam Tablet (Clonazepam + Escitalopram) is used to treat NEURO CNS. It contains Clonazepam (0.5mg) + Escitalopram Oxalate (10mg), which Clonazepam: Enhances GABA-A receptor activity; Escitalopram: Inhibits serotonin . Always consult your doctor before use. Take as prescribed.
- Generic Name: Clonazepam + Escitalopram
- Manufacturer: Docwin Healthcare
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ calmwin plus 0.5mg/10mg tablet Uses & Benefits
Generalized anxiety disorder, panic disorder, depression with anxiety
Off-label uses: Social anxiety disorder, post-traumatic stress disorder, insomnia
๐ Drug Information
| Generic Name(s) | Clonazepam + Escitalopram |
| Brand Name | Asiclopam Tablet |
| Manufacturer | Docwin Healthcare |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | NEURO CNS |
| Action Class | Benzodiazepine + SSRI |
| Route of Administration | Oral |
| Storage | Store at 20-25ยฐC, protect from light and moisture |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Clonazepam: Enhances GABA-A receptor activity; Escitalopram: Inhibits serotonin reuptake
Mechanism Steps
๐ก How to Take calmwin plus 0.5mg/10mg tablet
Follow your doctor's prescription exactly.
โ ๏ธ Side Effects of calmwin plus 0.5mg/10mg tablet
โ Common Side Effects
- Drowsiness
- Dizziness
- Fatigue
- Nausea
- Dry mouth
- Constipation
๐จ Serious Side Effects
- Respiratory depression
- Serotonin syndrome
- QT prolongation
- Suicidal thoughts
- Seizures
โ ๏ธ Rare Side Effects
- Blood dyscrasias
- Hepatotoxicity
- Stevens-Johnson syndrome
- Paradoxical reactions
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| MAOIs | Major | Risk of serotonin syndrome |
| CYP2C19 inhibitors | Major | Increased escitalopram levels |
| CNS depressants | Major | Enhanced sedation and respiratory depression |
| Warfarin | Moderate | Increased bleeding risk |
| Grapefruit juice | Minor | Increased escitalopram exposure |
๐จ Major Interactions
- MAOIs
- CYP2C19 inhibitors
- CYP3A4 inhibitors
- Other CNS depressants
โก Moderate Interactions
- SSRIs/SNRIs
- Antipsychotics
- Lithium
- Warfarin
โน๏ธ Minor Interactions
- Cimetidine
- Oral contraceptives
- Grapefruit juice
๐ฝ๏ธ Food Interactions
Grapefruit juice may increase escitalopram levels; food delays absorption
๐ท Alcohol Interaction
Avoid alcohol; increased CNS depression
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity, severe hepatic impairment, narrow-angle glaucoma, MAOI use, respiratory depression
๐ Monitoring Parameters
Liver function, renal function, ECG, suicidal ideation, sedation level
๐คฑ Lactation Safety
Not recommended; both drugs excreted in breast milk
๐ Overdose Management
Supportive care, flumazenil for clonazepam overdose, ECG monitoring for QT prolongation
โฐ Missed Dose
Take as soon as remembered; skip if near next dose; do not double