calcisome nasal spray - Calcitonin (Salmon) (200IU) medicine

calcisome nasal spray - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Krinon Remedies Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is calcisome nasal spray used for?

BMD Rise 200 IU Nasal Spray (Calcitonin (Salmon)) is used to treat PAIN ANALGESICS. It contains Calcitonin (Salmon) (200IU), which Binds to calcitonin receptors on osteoclasts, inhibiting osteoclast activity and. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Calcitonin (Salmon)
  • Manufacturer: Krinon Remedies Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š calcisome nasal spray Uses & Benefits

Postmenopausal osteoporosis; Paget's disease of bone; hypercalcemia of malignancy; bone pain due to osteolytic metastases.

Off-label uses: Reflex sympathetic dystrophy (RSD); phantom limb pain; spinal stenosis.

๐Ÿ“‹ Drug Information

Generic Name(s)Calcitonin (Salmon)
Brand NameBMD Rise 200 IU Nasal Spray
ManufacturerKrinon Remedies Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassBone resorption inhibitors- Calcitonin
Route of AdministrationIntranasal spray.
StorageStore at 2-8ยฐC (refrigerate); do not freeze; protect from light; use within 30 days after first use.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed through nasal mucosa; peak plasma concentrations achieved within 30-60 minutes.
DistributionDistributes widely; small volume of distribution; crosses placenta minimally.
Protein Binding30-40%
MetabolismMetabolized primarily in the kidneys via proteolysis; minor hepatic metabolism.
Half-LifeApproximately 1-2 hours (intranasal); 20-30 minutes (intravenous).
ExcretionRenal excretion of metabolites; less than 5% excreted unchanged.
BioavailabilityApproximately 3-5% (intranasal) relative to intramuscular injection.
Onset of ActionWithin 15-30 minutes.
Peak Plasma Time30-60 minutes.
Duration of Action6-8 hours.

How It Works

Binds to calcitonin receptors on osteoclasts, inhibiting osteoclast activity and reducing bone resorption; also increases renal excretion of calcium and phosphate.

Mechanism Steps

1Binds to calcitonin receptors on osteoclasts.
2Inhibits osteoclast activity and reduces bone resorption.
3Decreases serum calcium levels.

๐Ÿ’ก How to Take calcisome nasal spray

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of calcisome nasal spray

โœ… Common Side Effects

  • Nasal irritation
  • Rhinitis
  • Nausea
  • Flushing
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Hypocalcemia
  • Allergic reactions (including anaphylaxis)
  • Nasal ulceration
  • Epistaxis

โš ๏ธ Rare Side Effects

  • Bronchospasm
  • Angioedema
  • Tachyphylaxis
  • Visual disturbances

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Lithium Major Reduced lithium clearance; increased risk of lithium toxicity.
Loop diuretics Major Enhanced hypocalcemic effect; risk of severe hypocalcemia.
Bisphosphonates Major Additive reduction in bone resorption; increased risk of hypocalcemia.
Corticosteroids Moderate May reduce calcitonin's hypocalcemic effect.
Thiazide diuretics Moderate Increased risk of hypercalcemia due to reduced urinary calcium excretion.
Calcium supplements Moderate May antagonize hypocalcemic effect; monitor calcium levels.

๐Ÿšจ Major Interactions

  • Lithium
  • Loop diuretics
  • Bisphosphonates

โšก Moderate Interactions

  • Corticosteroids
  • Thiazide diuretics
  • Calcium supplements

โ„น๏ธ Minor Interactions

  • Vitamin D analogs
  • Estrogens
  • Progestins

๐Ÿฝ๏ธ Food Interactions

No significant food interactions reported.

๐Ÿท Alcohol Interaction

No known interaction; avoid excessive alcohol consumption.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to calcitonin or salmon protein; hypocalcemia.

๐Ÿ“Š Monitoring Parameters

Serum calcium, phosphate, alkaline phosphatase, renal function; nasal mucosa examination periodically.

๐Ÿคฑ Lactation Safety

Excreted in breast milk in small amounts; caution advised; consider risk-benefit.

๐Ÿ’Š Overdose Management

No specific antidote; supportive care; monitor serum calcium and electrolytes; treat hypocalcemia if symptomatic.

โฐ Missed Dose

Take as soon as remembered; if close to next dose, skip missed dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for calcisome nasal spray

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Alternative brands with exact same active ingredient (Calcitonin (Salmon) (200IU)):

Medical Note: Always consult your doctor before switching medications.

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