caelyx 2mg infusion - Doxorubicin (Liposomal) (2mg) medicine

caelyx 2mg infusion

4.5 (19 reviews)
๐Ÿญ Fulford India Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is caelyx 2mg infusion used for?

Adriamycin (Doxorubicin) is used to treat ANTI NEOPLASTICS. It contains Doxorubicin (Liposomal) (2mg), which Intercalates between DNA base pairs, inhibits topoisomerase II, and generates fr. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Doxorubicin
  • Manufacturer: Fulford India Ltd
  • Form: Allopathy
  • Pregnancy Category: D
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š caelyx 2mg infusion Uses & Benefits

Breast cancer, ovarian cancer, bladder cancer, thyroid cancer, gastric cancer, Hodgkin's lymphoma, non-Hodgkin's lymphoma, multiple myeloma, sarcoma, acute lymphoblastic leukemia, acute myeloid leukemia.

Off-label uses: Hepatocellular carcinoma, endometrial cancer, Wilms tumor, Ewing sarcoma.

๐Ÿ“‹ Drug Information

Generic Name(s)Doxorubicin
Brand NameAdriamycin
ManufacturerFulford India Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassANTI NEOPLASTICS
Action ClassAlkaloids-cytotoxic agents
Route of AdministrationIntravenous (IV) only; avoid intramuscular or subcutaneous.
StorageStore at 2-8ยฐC. Protect from light. Reconstituted solution stable for 24 hours at room temperature.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionIntravenous administration results in complete bioavailability. Oral absorption is poor and variable.
DistributionWidely distributed in tissues, with highest concentrations in liver, heart, lungs, kidneys, and spleen. Does not cross blood-brain barrier significantly.
Protein BindingApproximately 70-80% bound to plasma proteins.
MetabolismPrimarily metabolized in the liver by aldo-keto reductases to doxorubicinol (active metabolite) and other metabolites. Also undergoes reduction and deglycosylation.
Half-LifeTriphasic: initial half-life 12 minutes, intermediate 3.3 hours, terminal 20-48 hours.
ExcretionPrimarily biliary excretion (40-50% as unchanged drug and metabolites). Renal excretion accounts for 5-12%.
Bioavailability100% (intravenous). Oral bioavailability <5%.
Onset of ActionRapid, within minutes of IV administration.
Peak Plasma TimeImmediately after IV bolus.
Duration of ActionVariable, depends on cell cycle; effects persist for weeks due to DNA intercalation.

How It Works

Intercalates between DNA base pairs, inhibits topoisomerase II, and generates free radicals leading to DNA damage and cell death.

Mechanism Steps

1Intercalation between DNA base pairs
2Inhibition of topoisomerase II
3Generation of free radicals (reactive oxygen species)

๐Ÿ’ก How to Take caelyx 2mg infusion

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of caelyx 2mg infusion

โœ… Common Side Effects

  • Nausea
  • vomiting
  • alopecia
  • myelosuppression
  • mucositis
  • stomatitis
  • red urine

๐Ÿšจ Serious Side Effects

  • Cardiomyopathy
  • congestive heart failure
  • severe myelosuppression
  • secondary leukemia
  • tumor lysis syndrome
  • extravasation necrosis

โš ๏ธ Rare Side Effects

  • Hemolytic uremic syndrome
  • pulmonary fibrosis
  • hepatic veno-occlusive disease
  • anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Cyclophosphamide Major Increased cardiotoxicity risk
Trastuzumab Major Increased cardiotoxicity risk
Paclitaxel Major Increased myelosuppression
Verapamil Moderate Increased doxorubicin accumulation
Dexrazoxane Moderate Reduced cardiotoxicity (protective)
Phenobarbital Moderate Increased metabolism and reduced efficacy
Digoxin Minor Decreased digoxin absorption
Heparin Minor Incompatibility in solution

๐Ÿšจ Major Interactions

  • Cyclophosphamide
  • Trastuzumab
  • Paclitaxel
  • Radiation therapy

โšก Moderate Interactions

  • Verapamil
  • Dexrazoxane
  • Phenobarbital

โ„น๏ธ Minor Interactions

  • Digoxin
  • Heparin

๐Ÿฝ๏ธ Food Interactions

No significant food interactions.

๐Ÿท Alcohol Interaction

Avoid alcohol due to potential hepatotoxicity.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Severe hepatic impairment, severe myelosuppression, pre-existing cardiomyopathy, hypersensitivity, pregnancy.

๐Ÿ“Š Monitoring Parameters

CBC with differential, liver function tests, cardiac function (LVEF), renal function, uric acid levels.

๐Ÿคฑ Lactation Safety

Contraindicated; excreted in breast milk.

๐Ÿ’Š Overdose Management

Supportive care; severe myelosuppression may require G-CSF and antibiotics. Dexrazoxane may be used for extravasation or cardiotoxicity.

โฐ Missed Dose

Do not double dose. Contact physician for rescheduling.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

๐Ÿ”„ Substitutes for caelyx 2mg infusion

View All

Alternative brands with exact same active ingredient (Doxorubicin (Liposomal) (2mg)):

Medical Note: Always consult your doctor before switching medications.

โญ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Trusted Reviewer Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Happy Patient Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

Trusted Reviewer Jul 10, 2026

Effective and reliable. Worked as expected.

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