cachexiam 160 tablet

4.8 (14 reviews)

Megestrol (160mg)

🏭 Radiant Pharmaceuticals Ltd. 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 21, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 21, 2026

What is cachexiam 160 tablet used for?

Cravihenz (Megestrol) is used to treat ANTI NEOPLASTICS. It contains Megestrol (160mg), which Synthetic progestin; suppresses gonadotropins; may have direct cytotoxic effects. Always consult your doctor before use. Take as prescribed.

Generic Name: Megestrol
Manufacturer: Radiant Pharmaceuticals Ltd.
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

💊 cachexiam 160 tablet Uses & Benefits

Anorexia/cachexia in AIDS or cancer, Palliative treatment of advanced breast cancer, Endometrial cancer

Off-label uses: Weight gain in chronic illness, Hormone-sensitive tumors

📋 Drug Information

Generic Name(s)	Megestrol
Brand Name	Cravihenz
Manufacturer	Radiant Pharmaceuticals Ltd.
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	ANTI NEOPLASTICS
Action Class	Progestins (First generation)
Route of Administration	Oral
Storage	Store at 20-25°C (68-77°F); protect from moisture.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally; absorption may be enhanced with food.

DistributionDistributes widely; crosses placenta; enters breast milk.

Protein Binding~90%

MetabolismHepatic via CYP3A4 to active metabolites.

Half-Life13-104 hours (mean ~34 hours)

ExcretionUrine (50-80% as metabolites) and feces (20-30%).

Bioavailability~95%

Onset of ActionSeveral weeks for appetite stimulation; 2-4 weeks for antineoplastic effect.

Peak Plasma Time1-5 hours

Duration of ActionUp to 24 hours for appetite; prolonged for antineoplastic.

How It Works

Synthetic progestin; suppresses gonadotropins; may have direct cytotoxic effects on tumor cells.

Mechanism Steps

1Binds to progesterone receptors in hypothalamus and pituitary

2Suppresses gonadotropin (LH, FSH) release

3Reduces estrogen and testosterone production

💡 How to Take cachexiam 160 tablet

Follow your doctor's prescription exactly.

⚠️ Side Effects of cachexiam 160 tablet

✅ Common Side Effects

Increased appetite
Weight gain
Edema
Nausea
Flatulence
Rash

🚨 Serious Side Effects

Thromboembolism
Adrenal suppression
Hyperglycemia
Hepatotoxicity
Cushing's syndrome

⚠️ Rare Side Effects

Osteoporosis
Carpal tunnel syndrome
Ovarian suppression

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased INR and bleeding risk
Corticosteroids	Major	Additive immunosuppression
Rifampin	Major	Decreased megestrol efficacy
Ketoconazole	Major	Increased megestrol toxicity

🚨 Major Interactions

Warfarin
Corticosteroids
CYP3A4 inducers (e.g., rifampin)
CYP3A4 inhibitors (e.g., ketoconazole)

⚡ Moderate Interactions

Antidiabetic agents
Anticoagulants
Immunosuppressants

ℹ️ Minor Interactions

Oral contraceptives
Hormonal therapies

🍽️ Food Interactions

High-fat meals may increase absorption

🍷 Alcohol Interaction

May increase risk of hepatotoxicity; avoid excessive alcohol.

🛡️ Safety & Warnings

🚫 Contraindications

Pregnancy, Known hypersensitivity, Thromboembolic disorders, Severe hepatic impairment

📊 Monitoring Parameters

Liver function tests, Blood glucose, Signs of thromboembolism, Weight, Appetite

🤱 Lactation Safety

Contraindicated; excreted in breast milk.

💊 Overdose Management

Symptomatic and supportive; no specific antidote.

⏰ Missed Dose

Take as soon as remembered; if near next dose, skip missed dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 21, 2026

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🔄 Substitutes for cachexiam 160 tablet

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Alternative brands with exact same active ingredient (Megestrol (160mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.