C Clor 250mg Tablet
Clinical Background: Balrampur Hospital, Lucknow (Emergency Medicine) & SCPM Hospital | Standards: CDSCO, Indian Pharmacopoeia (IP) & WHO
When to Call Your Doctor IMMEDIATELY
- Severe allergic reaction: rash, itching, swelling of face, lips, or throat, difficulty breathing.
- Persistent diarrhea, abdominal cramps, or fever that may indicate a serious gut infection.
- Blood in stool or vomit.
- Yellowing of skin or eyes (jaundice).
- Decreased urine output or swelling in legs.
- Unusual bleeding or bruising.
- Seizures, especially in patients with kidney disease.
If experiencing severe symptoms, call emergency services immediately.
What is c clor 250mg tablet used for?
This medicine is a cephalosporin antibiotic used to treat bacterial infections of the respiratory tract, urinary tract, skin, and ears. It works by killing bacteria. It is not effective against viral infections.
- Generic Name: Cefaclor
- Manufacturer: Shalman Pharma Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 c clor 250mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एक एंटीबायोटिक है जिसका उपयोग बैक्टीरियल संक्रमणों के इलाज के लिए किया जाता है, जैसे कि श्वसन तंत्र, मूत्र मार्ग, त्वचा और कान के संक्रमण। यह बैक्टीरिया को मारकर काम करती है और वायरल संक्रमण जैसे सर्दी-जुकाम पर असरदार नहीं होती।
साइड इफेक्ट्स: आम दुष्प्रभावों में दस्त, जी मिचलाना, उल्टी, पेट दर्द और सिरदर्द शामिल हैं। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन एलर्जी, त्वचा पर चकत्ते, सांस लेने में कठिनाई, या गंभीर दस्त हो सकते हैं। किसी भी गंभीर लक्षण पर तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी एलर्जी और दवाओं के बारे में बताएं। इसे डॉक्टर के निर्देशानुसार ही लें और कोर्स पूरा करें। गर्भावस्था या स्तनपान के दौरान डॉक्टर से सलाह लें। शराब का सेवन न करें। दवा को कमरे के तापमान पर सूखी जगह पर रखें।
c clor 250mg tablet Uses & Benefits
Used to treat bacterial infections of the upper and lower respiratory tract, including pharyngitis, tonsillitis, and pneumonia caused by susceptible organisms.
Effective against uncomplicated urinary tract infections caused by susceptible bacteria such as Escherichia coli and Klebsiella species.
Prescribed for bacterial skin infections, including cellulitis and impetigo, when caused by susceptible strains.
Used in the treatment of middle ear infections caused by susceptible bacteria, particularly in children.
Effective against streptococcal pharyngitis and tonsillitis in patients who cannot use penicillin.
Off-Label & Investigational Uses:
Sometimes used as an alternative for early Lyme disease in patients allergic to doxycycline or amoxicillin, though not first-line.
Occasionally used for prevention of infective endocarditis in high-risk patients allergic to penicillin, but guidelines vary.
📋 Drug Information
| Generic Name(s) | Cefaclor |
| Brand Name | Articlor 50mg Drop |
| Manufacturer | Shalman Pharma Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | Cephalosporins: 2nd generation |
| Route of Administration | Oral |
| Storage | Store at room temperature between 15°C and 30°C (59°F to 86°F). Keep away from moisture and heat. Keep the container tightly closed. |
| Shelf Life | 24 months from the date of manufacture. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
Cefaclor exerts its bactericidal effect by binding to penicillin-binding proteins (PBPs) located on the inner bacterial cell membrane. This binding inhibits the transpeptidation reaction necessary for cross-linking peptidoglycan chains in the bacterial cell wall. As a result, the cell wall becomes weakened and osmotically unstable, leading to bacterial cell lysis and death. Cefaclor is active against a range of gram-positive and gram-negative bacteria, but it is susceptible to hydrolysis by certain beta-lactamases.
Mechanism Steps
💡 How to Take c clor 250mg tablet
Strength: 250 mg immediate-release tablet
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 250 mg every 8 hours for most mild to moderate infections. For more severe infections or those caused by less susceptible organisms, the dose may be increased to 500 mg every 8 hours. The maximum recommended daily dose is 4 grams. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Always follow your doctor's prescription. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing in children. |
| Elderly Dosage | Elderly patients may have reduced renal function, which can increase the risk of toxicity. Dose adjustment may be necessary based on renal function. Consult your doctor for individualized dosing. |
| Renal Impairment | In patients with renal impairment, dose adjustment is required. For creatinine clearance between 10 and 50 mL/min, the dose may be reduced or the dosing interval extended. For creatinine clearance less than 10 mL/min, the dose should be further reduced. Consult your doctor for specific guidance. |
| Hepatic Impairment | No specific dosage adjustment is established for hepatic impairment. However, caution is advised in patients with both hepatic and renal impairment. Consult your doctor. |
| Maximum Daily Dose | The maximum recommended daily dose is 4 grams (4000 mg) for adults. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of c clor 250mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Probenecid | Moderate | |
| Gentamicin | Moderate | |
| Furosemide | Moderate | |
| Oral contraceptives | Minor | |
| Antacids | Minor |
🚨 Major Interactions
- Warfarin
- Probenecid
⚡ Moderate Interactions
- Aminoglycosides (e.g., gentamicin)
- Loop diuretics (e.g., furosemide)
🍷 Alcohol Interaction
Alcohol may worsen certain side effects of this medicine, such as nausea, vomiting, and abdominal pain. It is advisable to avoid alcohol while taking this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity to cefaclor or any other cephalosporin antibiotic","Previous severe allergic reaction to penicillins (cross-reactivity possible)","Use in patients with a history of Clostridioides difficile-associated diarrhea"]
⚠️ Warnings & Precautions
["Before starting therapy, inquire about previous hypersensitivity reactions to cephalosporins, penicillins, or other allergens.","Use with caution in patients with renal impairment; dose adjustment may be necessary.","Prolonged use may result in overgrowth of non-susceptible organisms, including fungi.","If severe diarrhea occurs, consider the possibility of pseudomembranous colitis and initiate appropriate management.","Do not use this medicine for viral infections as it is ineffective and may promote resistance.","Patients with phenylketonuria should be aware that some formulations may contain phenylalanine.","Use in pregnancy only if clearly needed; consult your doctor.","Caution when driving or operating machinery if you experience dizziness or fatigue."]
🤱 Lactation Safety
Cefaclor is excreted in human breast milk in small amounts. It is generally considered safe during breastfeeding, but monitor the infant for diarrhea, thrush, or allergic reactions. Consult your doctor before use.
💊 Overdose Management
Overdose may cause nausea, vomiting, abdominal pain, and diarrhea. In severe cases, especially in patients with renal impairment, seizures may occur. Treatment is symptomatic and supportive. Hemodialysis may be considered to remove cefaclor from the blood in severe overdose. Contact a poison control center or emergency room immediately if overdose is suspected.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Before taking this medicine, inform your doctor if you are allergic to cefaclor, other cephalosporins, or penicillins. Do not use this medicine to treat viral infections. Take this medicine exactly as prescribed by your doctor, and do not skip doses or stop early. If you have kidney problems, your doctor may need to adjust your dose. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. This medicine may interact with other medications, so provide a complete list of all medicines you are taking. Avoid alcohol while taking this medicine, as it may worsen certain side effects. If you develop severe diarrhea, consult your doctor before taking any anti-diarrheal medication. Store this medicine at room temperature away from moisture and heat. Keep out of reach of children.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have decreased renal function, which may increase the risk of side effects. Dose adjustment may be necessary. Monitor kidney function regularly.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. It is generally considered safe but should be used only if clearly needed.
🏥 Post-Surgery Considerations
This medicine may be prescribed to prevent or treat surgical site infections. Follow your surgeon's instructions carefully.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may be used prophylactically before dental procedures in certain high-risk patients.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
If you experience dizziness or fatigue while taking this medicine, avoid strenuous exercise or operating heavy machinery. Light activities are generally safe.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness or fatigue in some people. If affected, avoid driving or operating machinery. Otherwise, you can continue your normal daily activities as tolerated.
🛑 When to Stop This Medicine
Do not stop taking this medicine before completing the full prescribed course, even if you feel better. If you experience severe side effects, contact your doctor before stopping.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended unless prescribed for a specific chronic infection. Prolonged use may lead to overgrowth of non-susceptible organisms, including fungi, and may increase the risk of antibiotic resistance. Regular monitoring of kidney and liver function may be required if used for extended periods. Consult your doctor for any concerns.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Depending on the infection and susceptibility, other antibiotics like amoxicillin, cefuroxime, or azithromycin may be used.
Evidence: Well-establishedFor viral infections, rest, fluids, and over-the-counter remedies may be used.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine does not interact with vaccines. However, if you are scheduled for a live vaccine, inform your doctor as antibiotics may affect the vaccine's effectiveness.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging along with a copy of your prescription. Keep it in your carry-on luggage to avoid temperature extremes. If crossing time zones, adjust dosing times gradually to maintain even intervals. Store at room temperature and avoid leaving it in hot cars or direct sunlight. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start feeling better within 2-3 days, but it is important to complete the full course as prescribed.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal or snack.
A: Take it as soon as you remember, but if it's almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.
A: It is classified as Pregnancy Category B. It should be used during pregnancy only if clearly needed. Consult your doctor.
A: It is advisable to avoid alcohol as it may worsen side effects like nausea and stomach upset.
🤔 Common Patient Concerns
🔄 Substitutes for c clor 250mg tablet
View AllAlternative brands with exact same active ingredient:
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vercef 250mg capsuleSun Pharmaceutical Industries Ltd ₹47.78 83.2% CHEAPER
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lyclor 250mg tabletLeeMed Pharmaceuticals ₹112.50 60.5% CHEAPER
-
colors 250mg tabletMefro Pharmaceuticals Pvt Ltd ₹140.63 50.7% CHEAPER
-
vercef 250mg tablet dtSun Pharmaceutical Industries Ltd ₹150.00 47.4% CHEAPER
-
Maclor 250mg TabletMeridian Medicare Ltd ₹150.00 47.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure the common cold.
Fact: This medicine is an antibiotic and is ineffective against viruses, including those causing the common cold. - Myth: You can stop taking this medicine once you feel better.
Fact: You must complete the full prescribed course to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe for everyone.
Fact: This medicine is not safe for individuals allergic to cephalosporins or penicillins. Always inform your doctor of any allergies.
🔄 Alternative Options
Generic Alternatives
- Cefaclor 250 mg tablet (generic)
Brand Alternatives
- Colors 250mg Tablet