Alburel 20gm Solution for Infusion: Comprehensive Medicine Guide
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or shortness of breath
- Chest pain or tightness
- Severe allergic reaction (swelling of face, lips, throat)
- Decreased urine output
- Sudden weight gain or swelling in legs
- Confusion or dizziness
- Fever with chills
If experiencing severe symptoms, call emergency services immediately.
What is buminate 20% infusion used for?
This medicine is a 20% human albumin solution used intravenously to expand blood volume in conditions like hypovolemia, severe burns, and ARDS. It works by drawing fluid into the bloodstream and must be given under medical supervision.
- Generic Name: Albumin
- Manufacturer: Baxter India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 buminate 20% infusion के बारे में (Hindi Summary)
उपयोग: यह दवा मानव एल्ब्यूमिन का 20% घोल है जो नस के माध्यम से दिया जाता है। इसका उपयोग रक्त की मात्रा बढ़ाने के लिए किया जाता है, जैसे कि गंभीर रक्तस्राव, जलन, और एआरडीएस जैसी स्थितियों में। यह शरीर में तरल पदार्थ को रक्त वाहिकाओं में खींचकर रक्तचाप को बनाए रखने में मदद करता है। यह दवा केवल अस्पताल में डॉक्टर की देखरेख में ही दी जानी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में ठंड लगना, बुखार, दाने, मतली और उल्टी शामिल हैं। गंभीर दुष्प्रभावों में एनाफिलेक्टिक शॉक, सांस लेने में कठिनाई, और पल्मोनरी एडिमा हो सकते हैं। यदि कोई गंभीर प्रतिक्रिया होती है, तो तुरंत डॉक्टर को सूचित करें।
सुरक्षा सलाह: यह दवा केवल अस्पताल में डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इसे स्वयं न लगाएं। यदि आपको दिल, गुर्दे, या जिगर की बीमारी है या रक्त उत्पादों से एलर्जी है, तो डॉक्टर को बताएं। इलाज के दौरान रक्तचाप, हृदय गति, और इलेक्ट्रोलाइट्स की निगरानी की जाएगी।
💊 buminate 20% infusion Uses & Benefits
[{"condition":"Hypovolemia","description":"Restores circulating blood volume in patients with acute blood loss or dehydration when crystalloids are insufficient.","evidence":"Well-established"},{"condition":"Severe burns","description":"Helps maintain plasma volume and oncotic pressure during the acute phase of burn management.","evidence":"Well-established"},{"condition":"Adult respiratory distress syndrome (ARDS)","description":"May improve oxygenation by reducing pulmonary edema when used with diuretics.","evidence":"Limited"},{"condition":"Nephrotic syndrome","description":"Temporarily increases serum albumin and reduces edema in patients with severe hypoalbuminemia.","evidence":"Limited"},{"condition":"Therapeutic plasma exchange","description":"Used as a replacement fluid during plasma exchange procedures.","evidence":"Well-established"},{"condition":"Major surgery","description":"Provides volume support in patients undergoing cardiopulmonary bypass or other major surgical procedures.","evidence":"Well-established"}]
Off-label uses: [{"condition":"Cirrhosis with ascites","description":"Sometimes used to improve effective circulating volume and renal function in patients with cirrhosis and ascites, but evidence is limited and risks must be weighed.","evidence":"Limited"},{"condition":"Ovarian hyperstimulation syndrome","description":"May be used to manage severe cases, but not a standard first-line treatment.","evidence":"Limited"}]
Primary treatment for: Hypovolemia
Also treats: Severe burns, Adult respiratory distress syndrome, Nephrotic syndrome, Cirrhosis with ascites
📋 Drug Information
| Generic Name(s) | Albumin |
| Brand Name | Alburel 20gm Solution for Infusion |
| Manufacturer | Baxter India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | BLOOD RELATED |
| Action Class | Colloids (Plasma substitutes) |
| Route of Administration | Intravenous |
| Storage | Store at room temperature (15-30°C). Do not freeze. Keep in the original container to protect from light. Do not use if the solution is cloudy or contains particles. |
| Shelf Life | Refer to the product label for the exact shelf life. Typically, the shelf life is 24 to 36 months from the date of manufacture when stored properly. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine works by increasing the colloid osmotic pressure of plasma. Albumin, the active ingredient, is a natural plasma protein that accounts for about 70-80% of the oncotic pressure of human plasma. When administered intravenously as a 20% solution, it draws fluid from the interstitial space into the intravascular compartment, thereby expanding plasma volume. This effect is greater than that of an equal volume of blood or crystalloid. Additionally, albumin binds and transports various endogenous and exogenous substances, including hormones, drugs, and toxins, although this transport function is not the primary therapeutic mechanism in volume expansion.
Mechanism Steps
💡 How to Take buminate 20% infusion
Strength: Solution for infusion, 20% (20 g/100 mL)
Dosage Information
| Adult Dosage | The dose of this medicine is individualized by a qualified clinician based on the patient's clinical condition, weight, and laboratory parameters. For hypovolemia, the usual adult dose is 100 to 200 mL of the 20% solution, but this may vary. For burns, larger volumes may be required. The infusion rate should be adjusted to the patient's response. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to fluid overload. Use with caution and monitor closely. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Monitor renal function and urine output. Dose adjustment may be necessary. Consult a nephrologist if needed. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Monitor liver function and albumin levels. Dose adjustment may be necessary. |
| Maximum Daily Dose | The maximum daily dose is not fixed and depends on the patient's condition. It should be determined by a qualified clinician. |
Dosage Timeline
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of buminate 20% infusion
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Diuretics | Major | |
| ACE inhibitors | Major | |
| Corticosteroids | Moderate | |
| NSAIDs | Moderate | |
| Antihypertensives | Minor |
🚨 Major Interactions
- Diuretics
- ACE inhibitors
⚡ Moderate Interactions
- Corticosteroids
- NSAIDs
🍷 Alcohol Interaction
Alcohol may worsen dehydration and electrolyte imbalances. Avoid alcohol during treatment with this medicine.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to albumin or any component of the formulation","Severe anemia","Cardiac failure","Renal failure with oliguria or anuria","History of allergic reactions to blood products"]
⚠️ Warnings & Precautions
["Administer only under medical supervision.","Monitor for signs of allergic reactions.","Avoid rapid infusion to prevent circulatory overload.","Use with caution in patients with cardiac or renal impairment.","Do not use if solution is cloudy or contains particles.","Discard unused portion; do not store for later use.","Ensure adequate hydration before infusion.","Monitor electrolyte levels during therapy."]
🤱 Lactation Safety
It is not known whether albumin is excreted in human breast milk. Because albumin is a large protein, it is unlikely to be present in breast milk in significant amounts. However, consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may lead to hypervolemia, pulmonary edema, and electrolyte imbalances. Treatment is supportive and symptomatic. Stop the infusion immediately and manage fluid overload with diuretics and oxygen as needed. Monitor vital signs and electrolytes closely.
⏰ Missed Dose
This medicine is administered by a healthcare professional in a controlled setting. Missed doses are unlikely to occur. If a dose is missed, consult your doctor for guidance. Do not attempt to self-administer.
Additional Safety Advice
This medicine must be administered only by a healthcare professional in a hospital or clinic setting. Do not self-administer. Inform your doctor if you have a history of heart disease, kidney disease, liver disease, or allergic reactions to blood products. Your doctor will monitor your blood pressure, heart rate, urine output, and electrolyte levels during and after the infusion. Do not use this medicine if the solution is cloudy, contains particles, or if the container is damaged. Discard any unused portion. This product is for single use only. Do not mix with other medications unless directed by a physician. If you experience any signs of allergic reaction such as rash, itching, swelling, or difficulty breathing, seek immediate medical attention.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are at higher risk of fluid overload and electrolyte imbalances. Use with caution and monitor closely.
🤰 Pregnancy Planning (TTC)
If you are planning pregnancy, consult your doctor before receiving this medicine. It is used only when clinically indicated.
🏥 Post-Surgery Considerations
This medicine may be used during or after surgery to maintain blood volume. Follow your surgeon's instructions.
🦷 Dental Procedures
Inform your dentist if you have recently received this medicine. No specific precautions are known, but your dentist may consult your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise immediately after infusion. Gradually resume normal activities as advised by your doctor.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine is given in a hospital setting. You may need to rest for a few hours after infusion. Driving is not recommended immediately after infusion. Follow your doctor's advice.
🛑 When to Stop This Medicine
Do not stop this medicine without consulting your doctor. It is administered under medical supervision, and the decision to stop is based on your clinical response.
📅 Long-Term Use Effects
Long-term use of this medicine is not common. It is typically used for acute conditions. Repeated infusions may be needed in chronic conditions like nephrotic syndrome, but this should be monitored by a specialist. Long-term effects are not well established.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
May be used for volume expansion in less severe cases.
Evidence: Well-establishedUsed if blood loss is significant and anemia is present.
Evidence: Well-established💉 Vaccination Considerations
💉 If You're Getting Vaccinated
No specific interactions with vaccines are known. However, consult your doctor before receiving any vaccine during treatment.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not freeze
✅ DO
Keep in original container
❌ DON'T
Do not use if cloudy or contains particles
✅ DO
Protect from light
❌ DON'T
Do not store in direct sunlight
✈️ Traveling with This Medicine
This medicine is administered in a hospital setting, so travel advice is not applicable. If you are traveling after treatment, carry a copy of your prescription and medical records. Store any remaining medication as directed by your doctor. Consult your doctor before traveling.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: This medicine starts working immediately after infusion, with peak effect within 30-60 minutes.
A: Yes, you can eat normally unless your doctor advises otherwise.
A: It depends on your condition. Your doctor will determine the frequency.
🤔 Common Patient Concerns
🔄 Substitutes for buminate 20% infusion
View AllAlternative brands with exact same active ingredient:
-
Albumin 20% InjectionBayer Pharmaceuticals Pvt Ltd ₹1,381.25 10.5% COSTLIER
-
albumina umana infusionTrans Pharmaceuticals ₹2,250.00 80% COSTLIER
-
cealb 20% infusionBharat Serums & Vaccines Ltd ₹2,906.25 132.5% COSTLIER
-
alba 20% infusionLife Medicare & Biotech Pvt Ltd ₹3,656.25 192.5% COSTLIER
-
verbulin 20% injectionPlasmaGen Biosciences Pvt Ltd ₹3,875.63 210.1% COSTLIER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can be used as a nutritional supplement.
Fact: This medicine is not a nutritional supplement. It is used for specific medical conditions and should only be given under medical supervision. - Myth: This medicine is safe for everyone.
Fact: This medicine is contraindicated in certain conditions such as severe anemia, cardiac failure, and renal failure with oliguria.