brupar 100mg tablet - Sparfloxacin (100mg) medicine

Artispar 100mg Tablet (Sparfloxacin): Complete Medicine Guide

No reviews yet
🏭 Brussels Laboratories Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
🤰 Pregnancy Category This medicine is not recommended for use during pregnancy. Animal studies have shown adverse effects on fetal development, and there are no adequate well-controlled studies in pregnant women. Consult your doctor for alternative antibiotics if you are pregnant or planning to become pregnant. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
12 min read
Evidence: Moderate
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in stool or vomit
  • Severe abdominal pain
  • Chest pain or difficulty breathing
  • Severe headache with visual changes
  • Sudden swelling of face, lips, or throat
  • Yellowing of skin or eyes
  • Decreased urine output
  • Irregular heartbeat or fainting
  • Tendon pain or swelling
  • Numbness or tingling in hands or feet

If experiencing severe symptoms, call emergency services immediately.

What is brupar 100mg tablet used for?

This medicine is an antibiotic used to treat bacterial infections such as pneumonia, bronchitis, and skin infections. It works by killing bacteria and is taken once daily. It is not recommended for pregnant women, children, or patients with heart rhythm problems.

  • Generic Name: Sparfloxacin (100mg)
  • Manufacturer: Brussels Laboratories Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 brupar 100mg tablet के बारे में (Hindi Summary)

उपयोग: यह दवा एक एंटीबायोटिक है जिसका उपयोग बैक्टीरियल संक्रमणों जैसे निमोनिया, ब्रोंकाइटिस और त्वचा संक्रमण के इलाज के लिए किया जाता है। यह बैक्टीरिया को मारकर काम करती है और दिन में एक बार ली जाती है। यह गर्भवती महिलाओं, बच्चों और हृदय की धड़कन की समस्या वाले रोगियों के लिए अनुशंसित नहीं है।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, दस्त, सिरदर्द, चक्कर आना और पेट दर्द शामिल हैं। ये आमतौर पर हल्के और अस्थायी होते हैं। कुछ रोगियों को धूप से एलर्जी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं लेकिन इनमें टेंडन टूटना, तंत्रिका क्षति, दौरे और हृदय ताल की समस्या शामिल हो सकती है। यदि आप कोई गंभीर लक्षण महसूस करें तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को लेने से पहले अपने डॉक्टर को अपनी सभी स्वास्थ्य स्थितियों के बारे में बताएं, खासकर यदि आपको हृदय की समस्या, गुर्दे की बीमारी या टेंडन विकार है। एंटासिड, सुक्राल्फेट, या आयरन, जिंक, मैग्नीशियम युक्त सप्लीमेंट्स को इस दवा से 2 घंटे पहले या 4 घंटे बाद लें। इस दवा को लेते समय पर्याप्त पानी पिएं। धूप से बचें और सनस्क्रीन का उपयोग करें। यदि आपको चक्कर आते हैं तो वाहन न चलाएं। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करें।

💡 Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

💊 brupar 100mg tablet Uses & Benefits

[{"condition":"Community-acquired pneumonia","description":"Used to treat pneumonia caused by susceptible bacteria such as Streptococcus pneumoniae, Haemophilus influenzae, and atypical pathogens.","evidence":"Well-established"},{"condition":"Acute bacterial exacerbation of chronic bronchitis","description":"Helps resolve bacterial infections in patients with chronic bronchitis, reducing symptoms and preventing complications.","evidence":"Well-established"},{"condition":"Skin and soft tissue infections","description":"Effective against certain bacterial skin infections, including cellulitis and abscesses, when caused by susceptible organisms.","evidence":"Moderate"}]

Off-label uses: [{"condition":"Traveler's diarrhea","description":"Sometimes used off-label for bacterial diarrhea, but other agents are generally preferred due to safety concerns.","evidence":"Limited"}]

Primary treatment for: Bacterial infections

Also treats: Community-acquired pneumonia, Acute bacterial exacerbation of chronic bronchitis, Skin and soft tissue infections

📋 Drug Information

Generic Name(s)Sparfloxacin (100mg)
Brand Namebrupar 100mg tablet
ManufacturerBrussels Laboratories Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassQuinolones/ Fluroquinolones
Route of AdministrationOral
StorageStore at room temperature between 15°C and 30°C (59°F to 86°F). Keep in a dry place, away from direct sunlight and moisture. Keep out of reach of children.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with a full glass of water, with or without food, but avoid taking it with dairy products or antacids.
2
Complete the full prescribed course, even if you feel better after a few days, to prevent antibiotic resistance.
3
Avoid excessive sun exposure and use sunscreen, as this medicine can cause photosensitivity reactions.
4
Do not drive or operate heavy machinery if you experience dizziness or drowsiness.
5
Report any tendon pain, numbness, or tingling in the hands or feet to your doctor immediately.
6
Inform your doctor if you have a history of heart rhythm problems or are taking other medications.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Fever with cough and chest pain
This medicine is commonly prescribed for community-acquired pneumonia.
Likely Use
✅
Chronic bronchitis with worsening symptoms
This medicine is used for acute bacterial exacerbations of chronic bronchitis.
Likely Use
✅
Skin redness and swelling
This medicine can treat certain skin and soft tissue infections.
Likely Use
❌
Common cold
This medicine is not effective against viral infections.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionThis medicine is well absorbed from the gastrointestinal tract after oral administration, with an absolute bioavailability of approximately 92%. Food does not significantly affect its absorption.
DistributionThis medicine is widely distributed throughout the body, including lung tissue, skin, and soft tissues. It achieves high concentrations in these target sites, which is beneficial for treating respiratory and skin infections.
Protein BindingApproximately 37% to 45% of this medicine is bound to plasma proteins.
MetabolismThis medicine undergoes limited metabolism in the liver, primarily through glucuronidation. It does not significantly induce or inhibit cytochrome P450 enzymes.
Half-LifeThe elimination half-life of this medicine is approximately 16 to 20 hours, allowing for once-daily dosing.
ExcretionThis medicine is primarily excreted unchanged in the feces (about 50%) and urine (about 50%). Renal impairment may require dose adjustment.
BioavailabilityThe oral bioavailability of this medicine is approximately 92%.
Onset of ActionThe onset of action is typically within 1 to 2 hours after oral administration, with peak plasma concentrations reached in about 3 to 5 hours.
Peak Plasma TimePeak plasma concentrations are achieved approximately 3 to 5 hours after oral administration.
Duration of ActionThe duration of action is approximately 24 hours, allowing for once-daily dosing.

How It Works

This medicine works by inhibiting bacterial DNA gyrase and topoisomerase IV, enzymes that are essential for DNA replication, transcription, repair, and recombination. By blocking these enzymes, it prevents bacterial cells from replicating and leads to bacterial death. This medicine is bactericidal, meaning it kills bacteria directly.

Mechanism Steps

1
Binding to DNA gyrase: This medicine binds to the DNA gyrase enzyme, which is responsible for supercoiling bacterial DNA during replication.
2
Inhibition of DNA replication: By blocking DNA gyrase, this medicine prevents the relaxation of supercoiled DNA, halting replication and transcription.
3
Binding to topoisomerase IV: This medicine also binds to topoisomerase IV, an enzyme involved in separating daughter DNA strands during cell division.
4
Bacterial cell death: The inhibition of these enzymes leads to double-strand DNA breaks and ultimately bacterial cell death.

💡 How to Take brupar 100mg tablet

Strength: Sparfloxacin 100 mg immediate-release tablet

1Take this medicine exactly as prescribed by your doctor.
2Swallow the tablet whole with a full glass of water.
3You may take it with or without food, but avoid taking it with dairy products, antacids, or mineral supplements.
4If you are taking antacids, sucralfate, or supplements containing iron, zinc, or magnesium, take them at least 2 hours before or 4 hours after this medicine.
5Do not crush, chew, or break the tablet unless instructed by your doctor.
6Complete the full course of therapy, even if you feel better after a few days.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 100 mg to 200 mg once daily, depending on the type and severity of the infection. The duration of treatment varies: for community-acquired pneumonia, 7 to 10 days; for acute bacterial exacerbation of chronic bronchitis, 5 to 7 days; for skin infections, 7 to 10 days. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. Take this medicine with a full glass of water, with or without food, but avoid taking it with dairy products or antacids.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may be more susceptible to tendon rupture, QT prolongation, and CNS effects. Dose adjustment may be necessary based on renal function. Use with caution and monitor closely.
Renal ImpairmentIn patients with renal impairment (creatinine clearance less than 50 mL/min), dose adjustment is required. The dose may need to be reduced or the dosing interval extended. Consult your doctor for specific recommendations.
Hepatic ImpairmentNo specific dose adjustment is recommended for patients with mild to moderate hepatic impairment. However, use with caution in severe hepatic impairment due to limited data.
Maximum Daily DoseThe maximum recommended daily dose is 200 mg.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset.
Dairy products
Avoid taking together
Calcium can bind to sparfloxacin and reduce its absorption.
Caffeine
Limit intake
May increase stimulant effects.

⏰ What to Do If You Miss a Dose

📌 Less than 12 hours have passed since the missed dose
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than 12 hours have passed since the missed dose
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of brupar 100mg tablet

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food to reduce nausea. If it persists, consult your doctor.
Diarrhea (Common (5-10%))
Stay hydrated. If diarrhea is severe or contains blood, contact your doctor.
Headache (Common (5-10%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Dizziness (Common (5-10%))
Avoid driving or operating machinery until you know how this medicine affects you.
Abdominal pain (Common (5-10%))
Take with food. If pain is severe, consult your doctor.

🚨 Serious Side Effects

Tendinitis or tendon rupture (Rare (<0.1%))
Stop taking this medicine and seek immediate medical attention if you experience pain, swelling, or rupture of a tendon.
Peripheral neuropathy (Rare (<0.1%))
Report symptoms such as numbness, tingling, burning, or weakness in the hands or feet to your doctor immediately.
Central nervous system effects (seizures, confusion) (Rare (<0.1%))
Seek immediate medical attention if you experience seizures, confusion, or hallucinations.
QT prolongation and arrhythmias (Rare (<0.1%))
Inform your doctor if you have palpitations, fainting, or irregular heartbeat. Avoid use with other QT-prolonging drugs.
Photosensitivity reactions (Uncommon (0.1-1%))
Avoid sun exposure and use sunscreen. If a severe skin reaction occurs, stop the medicine and consult your doctor.

⚠️ Rare Side Effects

Hepatotoxicity
Report yellowing of skin or eyes, dark urine, or severe abdominal pain to your doctor immediately.
Nephrotoxicity
Report decreased urine output or swelling to your doctor.
Blood dyscrasias
Report unusual bleeding, bruising, or signs of infection to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Warfarin Major
Amiodarone Major
Antacids Major
NSAIDs Major
Theophylline Major
Corticosteroids Moderate
Oral hypoglycemics Moderate
Probenecid Moderate
Caffeine Minor
Cyclosporine Minor

🚨 Major Interactions

  • Class IA and III antiarrhythmics (e.g., quinidine, amiodarone, sotalol)
  • Antacids, sucralfate, iron, zinc, magnesium supplements
  • Warfarin
  • NSAIDs (e.g., ibuprofen, naproxen)
  • Theophylline

⚡ Moderate Interactions

  • Corticosteroids
  • Oral hypoglycemics (e.g., glibenclamide)
  • Probenecid

🍷 Alcohol Interaction

Alcohol may increase the risk of central nervous system side effects such as dizziness, drowsiness, and confusion. It is advisable to avoid alcohol while taking this medicine.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to sparfloxacin or other quinolone antibiotics","History of tendon disorders associated with fluoroquinolone use","Patients with known QT prolongation or uncorrected hypokalemia","Concomitant use with other QT-prolonging drugs","Pregnancy and breastfeeding","Children under 18 years of age"]

⚠️ Warnings & Precautions

["This medicine may cause dizziness and lightheadedness. Avoid driving or operating machinery until you know how it affects you.","Avoid excessive sun exposure and use sunscreen, as this medicine can cause photosensitivity reactions.","Tendinitis and tendon rupture can occur, especially in patients over 60, those taking corticosteroids, and organ transplant recipients. Stop the medicine and consult your doctor if you experience tendon pain.","Peripheral neuropathy has been reported. Discontinue if symptoms occur.","Central nervous system effects including seizures, confusion, and hallucinations have been reported. Use with caution in patients with CNS disorders.","This medicine can exacerbate muscle weakness in patients with myasthenia gravis. Avoid use in these patients.","Do not take this medicine with antacids, sucralfate, or mineral supplements containing iron, zinc, or magnesium within 2 hours before or after.","Complete the full course of therapy as prescribed, even if symptoms improve, to prevent resistance."]

🤱 Lactation Safety

This medicine is excreted in human milk and may cause serious adverse reactions in nursing infants. It is not recommended for use during breastfeeding. Consult your doctor for alternative options.

💊 Overdose Management

In case of overdose, seek immediate medical attention. Symptoms of overdose may include nausea, vomiting, dizziness, and QT prolongation. Treatment is supportive and symptomatic. Monitor ECG and vital signs. There is no specific antidote. Hemodialysis is not effective in removing sparfloxacin from the body.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take a double dose to make up for a missed one.

Additional Safety Advice

General Safety

Before taking this medicine, inform your doctor if you have any heart conditions, especially irregular heartbeats or a history of QT prolongation. Avoid taking antacids, sucralfate, or supplements containing iron, zinc, or magnesium within 2 hours before or after this medicine, as they can reduce its absorption. Stay well hydrated while taking this medicine. Avoid excessive sunlight and use sunscreen. Do not drive or operate heavy machinery if you feel dizzy. Do not share this medicine with others, even if they have similar symptoms. Complete the full prescribed course, even if you feel better after a few days.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients are at higher risk of tendon rupture, QT prolongation, and central nervous system effects. Dose adjustment may be necessary based on renal function. Use with caution and monitor closely for any adverse effects.

🤰 Pregnancy Planning (TTC)

This medicine is not recommended for use during pregnancy or when planning to become pregnant. If you are trying to conceive, consult your doctor for alternative antibiotics. Use effective contraception while taking this medicine.

🏥 Post-Surgery Considerations

If you are scheduled for surgery, inform your surgeon that you are taking this medicine. It may need to be stopped before surgery due to the risk of bleeding and interactions with anesthetics. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist that you are taking this medicine before any dental procedure. It may interact with certain antibiotics or anesthetics used during dental work. Your dentist may recommend postponing elective procedures until you complete the course.

💚 Lifestyle Tips for Better Results

🏃
Maintain a healthy diet rich in fruits and vegetables to support your immune system.
🥗
Stay well hydrated by drinking plenty of water throughout the day.
😴
Get adequate rest to help your body fight the infection.
💧
Avoid excessive sun exposure and use sunscreen to prevent photosensitivity.
🧘
Practice good hygiene to prevent the spread of infection.
🌞
Complete the full course of antibiotics as prescribed.

🏋️ Exercise Considerations

Avoid strenuous exercise or heavy lifting while taking this medicine, as it may increase the risk of tendon rupture. If you experience joint or tendon pain, stop exercising and consult your doctor.

🥗 Diet Recommendations

Include probiotic-rich foods like yogurt to maintain gut health.
Avoid dairy products within 2 hours of taking this medicine.
Limit caffeine intake to prevent jitteriness.
Stay hydrated with water and clear fluids.
Eat a balanced diet to support recovery.

💼 Impact on Daily Work & Life

This medicine may cause dizziness, drowsiness, or confusion, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is also important to avoid excessive sun exposure if you work outdoors.

🛑 When to Stop This Medicine

Do not stop taking this medicine without consulting your doctor, even if you feel better. Stopping early can lead to incomplete treatment and antibiotic resistance. If you experience serious side effects such as tendon pain, numbness, or irregular heartbeat, stop the medicine and seek immediate medical attention.

📅 Long-Term Use Effects

Long-term use of this medicine may increase the risk of antibiotic resistance and superinfections. It can also cause tendon damage, peripheral neuropathy, and cardiac arrhythmias. Regular monitoring of renal and hepatic function is recommended if prolonged therapy is necessary. Use the shortest effective duration.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Other antibiotics

Depending on the infection and susceptibility, other antibiotics such as levofloxacin or moxifloxacin may be used.

Evidence: Well-established
Supportive care

Rest, hydration, and fever control can complement antibiotic therapy.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

This medicine does not interact with vaccines. However, if you are due for any vaccinations, inform your doctor as antibiotics may affect the response to certain live vaccines. Generally, inactivated vaccines can be given safely.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging along with a copy of your prescription. Store it at room temperature and protect it from moisture and direct sunlight. If crossing time zones, adjust your dosing schedule to maintain approximately 24 hours between doses. Check customs regulations for carrying prescription medicines in your destination country. Always keep this medicine in your carry-on luggage to avoid loss or temperature extremes.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 45-year-old office worker with community-acquired pneumonia
Started this medicine as prescribed for pneumonia. Within 3 days, fever and cough improved significantly. Emphasized taking it with water and avoiding antacids. Completed the 10-day course and recovered fully.
💡 Lesson: Consistency with prescribed dose and completing the full course leads to successful treatment.
👤 A 60-year-old man with chronic bronchitis
Experienced acute exacerbation of chronic bronchitis and was prescribed this medicine. Noticed improvement in breathing and reduced cough after 5 days. Reported mild nausea, which was managed by taking the medicine with food.
💡 Lesson: Taking this medicine with food can reduce stomach upset and improve tolerability.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: You may start feeling better within 2 to 3 days, but it is important to complete the full course as prescribed.

Q: Can I take this medicine with food?

A: You can take this medicine with or without food, but avoid taking it with dairy products, antacids, or mineral supplements as they can reduce its absorption.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double dose.

Q: Is this medicine safe during pregnancy?

A: This medicine is not recommended during pregnancy as it may harm the developing baby. Consult your doctor for alternative antibiotics.

Q: Can I drink alcohol while taking this medicine?

A: It is advisable to avoid alcohol as it may increase the risk of central nervous system side effects such as dizziness and drowsiness.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?

🔄 Substitutes for brupar 100mg tablet

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: This medicine can cure viral infections like the common cold.
    Fact: This medicine is an antibiotic and is only effective against bacterial infections. It does not treat viral infections.
  • Myth: You can stop taking this medicine as soon as you feel better.
    Fact: You must complete the full prescribed course to prevent the infection from returning and to avoid antibiotic resistance.
  • Myth: This medicine is safe for everyone.
    Fact: This medicine is not safe for pregnant women, children, and patients with certain heart conditions or tendon disorders.

🔄 Alternative Options

Generic Alternatives

  • Sparfloxacin 100 mg tablet

Brand Alternatives

  • Artispar 100mg Tablet

📊 Comparison with Similar Medicines

[{"medicine":"Sparfloxacin","class":"Fluoroquinolone","half_life":"16-20 hours","route":"Oral","common_uses":"Pneumonia, bronchitis, skin infections"},{"medicine":"Levofloxacin","class":"Fluoroquinolone","half_life":"6-8 hours","route":"Oral/IV","common_uses":"Pneumonia, sinusitis, urinary tract infections"},{"medicine":"Moxifloxacin","class":"Fluoroquinolone","half_life":"12 hours","route":"Oral/IV","common_uses":"Pneumonia, bronchitis, skin infections"}]

😊 Was this information helpful?

Browse Medicines A-Z

A B C D E F G H I J K L M N O P Q R S T U V W X Y Z
Back to Medicines Directory