brox-cz tablet - Cetirizine (5mg) + Ambroxol (60mg) medicine

Brox-CZ Tablet - Uses, Price, Side Effects

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๐Ÿญ Rax Health Care Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 30, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 30, 2026

What is brox-cz tablet used for?

Brox-CZ Tablet is a combination medicine containing Cetirizine (5mg) and Ambroxol (60mg). Cetirizine is an antihistamine that relieves allergy symptoms like sneezing and runny nose, while Ambroxol is a mucolytic that helps thin and loosen mucus in the airways, making it easier to cough up. It is used for treating allergic cough, respiratory congestion, and associated symptoms.

  • Generic Name: Cetirizine + Ambroxol
  • Manufacturer: Rax Health Care Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š brox-cz tablet Uses & Benefits

Allergic rhinitis, cough with thick mucus, upper respiratory tract infections

Off-label uses: Chronic urticaria, COPD exacerbations

๐Ÿ“‹ Drug Information

Generic Name(s)Cetirizine + Ambroxol
Brand NameAmcold
ManufacturerRax Health Care Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassAntihistamine + Mucolytic
Route of AdministrationOral
StorageStore at 25ยฐC (77ยฐF); protect from light and moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionCetirizine: Well absorbed orally; Ambroxol: Rapidly absorbed from GI tract
DistributionCetirizine: Vd 0.5 L/kg; Ambroxol: Widely distributed, crosses placenta
Protein BindingCetirizine: 93%; Ambroxol: 90%
MetabolismCetirizine: Minimal hepatic metabolism; Ambroxol: Hepatic via glucuronidation
Half-LifeCetirizine: 8-11 hours; Ambroxol: 7-12 hours
ExcretionCetirizine: Renal (60% unchanged); Ambroxol: Renal (90% as metabolites)
BioavailabilityCetirizine: ~70%; Ambroxol: ~70-80%
Onset of ActionCetirizine: 1 hour; Ambroxol: 30 minutes
Peak Plasma TimeCetirizine: 1-2 hours; Ambroxol: 1-3 hours
Duration of ActionCetirizine: 24 hours; Ambroxol: 6-12 hours

How It Works

Cetirizine: Selective H1 receptor antagonist; Ambroxol: Increases airway secretion and reduces mucus viscosity

Mechanism Steps

1Cetirizine blocks H1 receptors, preventing histamine-mediated allergic responses
2Ambroxol stimulates serous bronchial glands, increasing fluid secretion
3Ambroxol depolymerizes mucopolysaccharides, reducing mucus viscosity

๐Ÿ’ก How to Take brox-cz tablet

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of brox-cz tablet

โœ… Common Side Effects

  • Drowsiness
  • Dry mouth
  • Fatigue
  • Nausea

๐Ÿšจ Serious Side Effects

  • Severe allergic reactions
  • Hepatotoxicity (rare)
  • Arrhythmias (rare)

โš ๏ธ Rare Side Effects

  • Thrombocytopenia
  • Stevens-Johnson syndrome
  • Anaphylaxis

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Alcohol Moderate Increased sedation and dizziness
CNS Depressants Moderate Enhanced sedative effect
MAO Inhibitors Major Increased risk of hypertensive crisis

๐Ÿšจ Major Interactions

  • CNS depressants
  • Alcohol
  • MAOIs

โšก Moderate Interactions

  • Anticholinergics
  • CYP3A4 inhibitors

โ„น๏ธ Minor Interactions

  • Theophylline
  • Digoxin

๐Ÿฝ๏ธ Food Interactions

Food may delay absorption of cetirizine

๐Ÿท Alcohol Interaction

Increased CNS depression

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to any component, severe renal impairment (CrCl <10 mL/min)

๐Ÿ“Š Monitoring Parameters

Renal function, CNS effects, respiratory status

๐Ÿคฑ Lactation Safety

Cetirizine excreted in milk; Ambroxol likely safe

๐Ÿ’Š Overdose Management

Symptomatic and supportive; gastric lavage if recent

โฐ Missed Dose

Take as soon as remembered; skip if almost time for next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 30, 2026

๐Ÿ”— View Profile

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