brotasin syrup - Bromhexine (2mg/5ml) + Guaifenesin (50mg/5ml) medicine

Asmaril Syrup: Complete Guide to Uses, Dosage, Side Effects, and Safety

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🏭 Eastern Drug 📦 Varies by brand 💊 Allopathy 📅 Updated: Sep 22, 2026
🤰 Pregnancy Category Not established from the available information. Consult your doctor if you are pregnant or planning to become pregnant. This medicine should be used during pregnancy only if clearly needed and prescribed by a doctor. 📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Moderate for symptomatic relief of productive cough.
Reviewed by
SaathiMed Expert Panel | Sep 22, 2026

When to Call Your Doctor IMMEDIATELY

  • Blood in vomit or black, tarry stools
  • Severe abdominal pain
  • Difficulty breathing or wheezing
  • Swelling of the face, lips, tongue, or throat
  • Severe rash or blistering of the skin
  • Yellowing of the skin or eyes
  • Decreased urine output
  • Persistent fever or cough lasting more than 7 days

If experiencing severe symptoms, call emergency services immediately.

What is brotasin syrup used for?

This medicine is a combination cough syrup containing bromhexine and guaifenesin. It works by thinning and loosening mucus in the airways, making it easier to cough out. It is used for productive coughs with phlegm and should be taken as directed by a doctor.

  • Generic Name: Bromhexine (2mg/5ml) + Guaifenesin (50mg/5ml)
  • Manufacturer: Eastern Drug
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 brotasin syrup के बारे में (Hindi Summary)

उपयोग: यह दवा ब्रोमहेक्सिन और गुआइफेनेसिन का संयोजन है, जिसका उपयोग बलगम वाली खांसी (कफ वाली खांसी) के इलाज में किया जाता है। यह बलगम को पतला करके उसे बाहर निकालने में मदद करती है, जिससे छाती की जकड़न और खांसी में राहत मिलती है। यह दवा तीव्र और दीर्घकालिक ब्रोंकाइटिस जैसी स्थितियों में भी उपयोगी है। इसे डॉक्टर की सलाह के अनुसार ही लें।

साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, पेट में असुविधा, दस्त, सिरदर्द, चक्कर आना और नींद आना शामिल हैं। ये आमतौर पर हल्के होते हैं और अपने आप ठीक हो जाते हैं। यदि आपको गंभीर एलर्जी, सांस लेने में कठिनाई, या त्वचा पर चकत्ते जैसे लक्षण दिखें, तो तुरंत डॉक्टर से संपर्क करें।

सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुद से कोई भी दवा न लें। इस दवा को लेते समय भरपूर पानी पिएं। यदि आपको चक्कर या नींद आ रही हो तो वाहन न चलाएं। 7 दिनों से अधिक इस दवा का उपयोग न करें। यदि खांसी ठीक न हो या बुखार, दाने, या सांस लेने में तकलीफ हो तो डॉक्टर से मिलें। गर्भवती या स्तनपान कराने वाली महिलाएं डॉक्टर से सलाह लें।

💡 Did You Know? The first generic medicine was introduced in India in 1970 after the Patents Act was amended.

💊 brotasin syrup Uses & Benefits

[{"condition":"Productive cough (with phlegm)","description":"Helps loosen and thin mucus, making it easier to cough out and relieving chest congestion.","evidence":"Well-established"},{"condition":"Acute bronchitis","description":"Provides symptomatic relief by aiding in the clearance of excessive mucus from the airways.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage chronic mucus hypersecretion and facilitate expectoration.","evidence":"Well-established"},{"condition":"Respiratory conditions with thick mucus","description":"May be used in conditions like COPD or asthma where thick mucus is a problem, but only under medical supervision.","evidence":"Limited"}]

Off-label uses: []

Primary treatment for: Productive cough

Also treats: Acute bronchitis, Chronic bronchitis, COPD, Asthma

📋 Drug Information

Generic Name(s)Bromhexine (2mg/5ml) + Guaifenesin (50mg/5ml)
Brand Namebrotasin syrup
ManufacturerEastern Drug
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action Class
Route of AdministrationOral
StorageStore at room temperature (15-30°C) in a dry place, away from direct sunlight. Keep the bottle tightly closed. Do not refrigerate unless specified on the label.
Shelf Life24 months from the date of manufacture.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Take this medicine with food to reduce the risk of stomach upset.
2
Drink plenty of water throughout the day to help loosen mucus.
3
Avoid taking this medicine with cough suppressants unless specifically directed by your doctor.
4
Do not use this medicine for a dry, irritating cough as it may not be effective.
5
If your cough does not improve within 7 days, consult your doctor for further evaluation.
6
Avoid alcohol while taking this medicine as it can increase drowsiness and dizziness.
7
Keep a record of your doses to avoid missing or doubling up.
8
If you are pregnant or breastfeeding, consult your doctor before using this medicine.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

Productive cough with phlegm
This medicine is commonly prescribed for this.
Likely Use
Dry cough
This medicine is not effective for dry cough and may be harmful.
Not Primary
Chest congestion
This medicine helps loosen mucus and relieve congestion.
Likely Use
Fever
This medicine is not a fever reducer. Consult a doctor if fever persists.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionBromhexine is rapidly absorbed from the gastrointestinal tract after oral administration. Guaifenesin is also absorbed from the gastrointestinal tract. The exact bioavailability of the combination in this syrup is not established from the available information.
DistributionBromhexine is widely distributed in the body, including the lungs. Guaifenesin distribution is not well characterized. Protein binding information is not established from the available information.
Protein BindingNot established from the available information.
MetabolismBromhexine undergoes extensive first-pass metabolism in the liver, primarily by cytochrome P450 enzymes. Guaifenesin is metabolized in the liver, but the exact pathways are not fully established.
Half-LifeThe elimination half-life of bromhexine is approximately 1-2 hours. The half-life of guaifenesin is not well established from the available information.
ExcretionBromhexine and its metabolites are primarily excreted in the urine. Guaifenesin and its metabolites are also excreted in the urine.
BioavailabilityThe oral bioavailability of bromhexine is low due to first-pass metabolism, approximately 20-30%. The bioavailability of guaifenesin is not well established from the available information.
Onset of ActionThe onset of action for bromhexine is typically within 30 minutes to 1 hour after oral administration. For guaifenesin, onset is also within 30 minutes to 1 hour. The full effect on mucus may take a few doses.
Peak Plasma TimePeak plasma concentration for bromhexine is reached approximately 1 hour after oral administration. For guaifenesin, peak levels are reached within 1-2 hours.
Duration of ActionThe duration of action for bromhexine is approximately 4-6 hours. For guaifenesin, the duration is about 4-6 hours. The syrup is usually taken 3 to 4 times a day.

How It Works

This medicine combines two active ingredients with complementary actions. Bromhexine is a mucolytic that reduces the viscosity of mucus by breaking down the network of mucopolysaccharide fibers, making the mucus thinner and easier to clear. Guaifenesin is an expectorant that increases the volume and reduces the viscosity of respiratory tract secretions by increasing the water content of mucus, thereby promoting ciliary action and facilitating the removal of mucus from the airways. Together, they help in the effective clearance of chest congestion.

Mechanism Steps

1
Bromhexine breaks down mucus structure: Bromhexine disrupts the structure of mucopolysaccharide fibers in mucus, reducing its thickness and stickiness.
2
Guaifenesin increases mucus water content: Guaifenesin draws water into the mucus, making it less viscous and easier to cough up.
3
Enhanced ciliary action: The thinner mucus is more easily moved by the cilia lining the airways, aiding in its expulsion.
4
Productive cough: The combined effect leads to a more effective cough that clears the airways, providing symptomatic relief.

💡 How to Take brotasin syrup

Strength: Each 5 ml of syrup contains Bromhexine 2 mg and Guaifenesin 50 mg.

1Shake the bottle well before each use.
2Use a measuring cup or spoon to measure the exact dose.
3Take the medicine orally, with or without food. Taking it with food may reduce stomach upset.
4Drink a glass of water after taking the medicine to help loosen mucus.
5Wash the measuring cup after each use.
6Do not take more than the prescribed dose.
7If you miss a dose, follow the missed dose instructions.

Dosage Information

Adult DosageThe usual adult dose of this medicine is 10 ml (2 teaspoons) taken three to four times a day, or as directed by your doctor. The dose may vary depending on the severity of your condition and your response to treatment. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician. This medicine is not recommended for children under 2 years of age. For children above 2 years, the dose is usually determined by the doctor based on the child's age and weight.
Elderly DosageElderly patients may be more sensitive to the side effects of this medicine, especially dizziness and drowsiness. Use with caution. Dose adjustment may be necessary based on renal and hepatic function. Consult your doctor for appropriate dosing.
Renal ImpairmentDose adjustment may be required in patients with severe kidney disease. Consult your doctor for appropriate dosing.
Hepatic ImpairmentDose adjustment may be required in patients with severe liver disease. Consult your doctor for appropriate dosing.
Maximum Daily DoseThe maximum daily dose for adults is generally 40 ml (8 teaspoons) in divided doses, but this should not be exceeded without medical advice. For children, the maximum dose is determined by the doctor.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

With food
Take with meals
Reduces stomach upset and nausea.
Water
Drink plenty
Helps loosen mucus and soothe the throat.

⏰ What to Do If You Miss a Dose

📌 Less than half the dosing interval has passed
→ Take the missed dose as soon as you remember.
💡 Continue with the regular schedule.
📌 More than half the dosing interval has passed
→ Skip the missed dose.
💡 Do not double dose to catch up.

⚠️ Side Effects of brotasin syrup

✅ Common Side Effects

Nausea (Common (5-10%))
Take with food or milk to reduce stomach upset. If it persists, consult your doctor.
Vomiting (Common (5-10%))
Stay hydrated with small sips of water. If vomiting is severe or persistent, contact your doctor.
Stomach discomfort (Common (5-10%))
Take after meals. Avoid spicy or fatty foods. If discomfort continues, consult your doctor.
Diarrhea (Common (5-10%))
Drink plenty of fluids to prevent dehydration. If diarrhea is severe or lasts more than 2 days, consult your doctor.
Headache (Uncommon (1-5%))
Rest and stay hydrated. If headache is severe or persistent, consult your doctor.
Dizziness (Uncommon (1-5%))
Avoid driving or operating machinery until you feel normal. If dizziness persists, consult your doctor.
Drowsiness (Uncommon (1-5%))
Avoid activities requiring alertness. If drowsiness is excessive, consult your doctor.

🚨 Serious Side Effects

Severe allergic reaction (anaphylaxis) (Rare (<0.1%))
Seek immediate medical attention if you experience swelling of the face, lips, tongue, or throat, difficulty breathing, or a severe rash.
Severe skin reactions (e.g., Stevens-Johnson syndrome) (Rare (<0.1%))
Stop the medicine and seek immediate medical help if you develop a painful rash, blisters, or peeling skin.
Gastrointestinal bleeding (Rare (<0.1%))
Seek immediate medical attention if you notice blood in vomit or black, tarry stools.

⚠️ Rare Side Effects

Bronchospasm
Seek immediate medical attention if you experience wheezing or difficulty breathing.
Liver enzyme elevation
Report any yellowing of skin or eyes, dark urine, or severe fatigue to your doctor.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Codeine Major
Dextromethorphan Major
MAOIs Major
Atropine Moderate
Antihistamines Moderate
Amoxicillin Moderate
Erythromycin Moderate
Diuretics Minor

🚨 Major Interactions

  • Cough suppressants (e.g., codeine, dextromethorphan)
  • Monoamine oxidase inhibitors (MAOIs)

⚡ Moderate Interactions

  • Anticholinergic drugs (e.g., atropine, antihistamines)
  • Antibiotics (e.g., amoxicillin, erythromycin)

🍷 Alcohol Interaction

Alcohol may increase the risk of dizziness, drowsiness, and stomach upset while taking this medicine. It is advisable to avoid alcohol consumption during treatment.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to bromhexine, guaifenesin, or any component of the formulation","Children under 2 years of age","Active peptic ulcer disease","Severe liver disease","Severe kidney disease"]

⚠️ Warnings & Precautions

["Do not use for a dry, non-productive cough.","If cough persists for more than 7 days, recurs, or is accompanied by fever, rash, or persistent headache, consult a doctor.","Use with caution in patients with a history of peptic ulcer.","Use with caution in patients with asthma or other respiratory conditions.","Avoid driving or operating machinery if you experience dizziness or drowsiness.","Do not exceed the recommended dose.","Keep out of reach of children."]

🤱 Lactation Safety

It is not known whether bromhexine and guaifenesin pass into breast milk. Consult your doctor before using this medicine while breastfeeding. The doctor will weigh the benefits and risks.

💊 Overdose Management

Overdose may cause nausea, vomiting, diarrhea, and abdominal discomfort. In case of overdose, seek immediate medical attention. Treatment is symptomatic and supportive. There is no specific antidote.

⏰ Missed Dose

If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.

Additional Safety Advice

General Safety

Take this medicine exactly as directed by your doctor. Do not exceed the recommended dose. Drink plenty of water while taking this medicine to help loosen mucus. Avoid driving or operating heavy machinery if you feel dizzy or drowsy. Do not take this medicine for more than 7 days without consulting your doctor. If your cough persists or worsens, or if you develop a fever, rash, or difficulty breathing, seek medical attention. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Keep this medicine out of reach of children.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more sensitive to the side effects of this medicine, especially dizziness, drowsiness, and confusion. Use with caution. Dose adjustment may be needed based on kidney and liver function. Consult your doctor.

🤰 Pregnancy Planning (TTC)

If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this medicine during pregnancy is not well established. Your doctor will decide if it is appropriate for you.

🏥 Post-Surgery Considerations

If you have recently undergone surgery, consult your doctor before taking this medicine. It may interact with other medications or affect your recovery.

🦷 Dental Procedures

Inform your dentist if you are taking this medicine before any dental procedure. It may cause dry mouth, which can affect dental work.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated by drinking plenty of fluids, especially water and warm soups.
🥗
Use a humidifier or take steamy showers to help loosen mucus.
😴
Avoid smoking and exposure to secondhand smoke.
💧
Get plenty of rest to help your body recover.
🧘
Gargle with warm salt water to soothe a sore throat.
🌞
Avoid alcohol and caffeine, which can dehydrate you.

🏋️ Exercise Considerations

While taking this medicine, you may experience dizziness or drowsiness. Avoid strenuous exercise or activities that require alertness until you know how this medicine affects you. Light activities like walking are generally safe.

🥗 Diet Recommendations

Drink warm fluids like herbal tea, soup, and broth.
Include honey and ginger in your diet to soothe the throat.
Avoid cold, sugary, and processed foods that can worsen mucus.
Eat plenty of fruits and vegetables rich in vitamin C.
Avoid dairy products if they seem to thicken your mucus.

💼 Impact on Daily Work & Life

This medicine may cause dizziness or drowsiness in some people. Avoid driving or operating heavy machinery until you know how it affects you. It is generally safe to continue desk work, but take breaks and stay hydrated.

🛑 When to Stop This Medicine

Stop taking this medicine and consult your doctor if your cough does not improve within 7 days, or if you develop fever, rash, or difficulty breathing. Do not stop abruptly if you have been taking it for a long time without consulting your doctor.

📅 Long-Term Use Effects

This medicine is intended for short-term use only. Prolonged use may lead to unnecessary side effects and may mask an underlying condition. If your cough persists for more than 7 days, consult a doctor for further evaluation. Long-term use should be avoided unless specifically directed by a doctor.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Steam inhalation

Inhaling steam can help loosen mucus and relieve congestion.

Evidence: Well-established
Saline nasal irrigation

Rinsing nasal passages with saline can help clear mucus.

Evidence: Well-established
Honey and lemon

A warm mixture of honey and lemon can soothe the throat and reduce cough.

Evidence: Limited

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your doctor about all medicines you are taking.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not refrigerate unless specified

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Keep away from direct sunlight

❌ DON'T

Do not store in bathroom cabinet

✅ DO

Keep out of reach of children

❌ DON'T

Do not use after expiry date

✈️ Traveling with This Medicine

When traveling, carry this medicine in its original packaging with the prescription label intact. Keep a copy of your prescription with you. Store it at room temperature and away from direct sunlight. If traveling across time zones, continue your regular dosing schedule as close as possible. Check customs regulations for carrying medications. Always pack it in your carry-on luggage.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 35-year-old man with acute bronchitis
Rajesh developed a severe cough with thick yellow phlegm after a cold. His doctor prescribed this medicine. He took it three times a day with meals and drank plenty of water. Within three days, his cough became more productive and his chest congestion eased. He completed the 5-day course as advised.
💡 Lesson: Taking this medicine with food and staying hydrated can enhance its effectiveness and reduce stomach upset.
👤 A 60-year-old woman with chronic bronchitis
Mrs. Sharma, a chronic bronchitis patient, often struggled with thick mucus. Her doctor added this medicine to her regimen during exacerbations. She found that it helped her clear her airways better, but she experienced mild nausea initially. Taking it after meals solved the problem.
💡 Lesson: This medicine can be beneficial for chronic bronchitis, but side effects like nausea can be managed by taking it with food.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: This medicine usually starts working within 30 minutes to 1 hour after taking a dose. You may notice that your cough becomes more productive and mucus is easier to cough out. However, the full effect may take a few doses.

Q: Can I take this medicine with other cough medicines?

A: You should not take this medicine with other cough suppressants (like codeine or dextromethorphan) because they can suppress the cough reflex and lead to mucus buildup. Always consult your doctor before combining any medicines.

Q: Is this medicine safe for children?

A: This medicine is not recommended for children under 2 years of age. For children above 2 years, consult a pediatrician for appropriate dosing.

Q: Can I take this medicine if I am pregnant?

A: Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant. The doctor will weigh the benefits and risks.

Q: What should I do if I miss a dose?

A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine long-term?
  • Will it affect my kidney function?
  • Can I drive after taking this medicine?
  • Does it interact with my blood pressure medicine?
  • What if I miss a dose?
  • Can I drink alcohol while taking this?
  • Is it safe for children?
  • Can I take it during pregnancy?

🔄 Substitutes for brotasin syrup

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Asmaril syrup can cure any type of cough.
    Fact: This medicine is only effective for productive coughs with phlegm. It is not useful for dry coughs and may even be harmful if used inappropriately.
  • Myth: Asmaril syrup is safe to take without a prescription.
    Fact: This medicine should be taken only when prescribed by a doctor. Self-medication can lead to inappropriate use and potential side effects.
  • Myth: Asmaril syrup can be taken indefinitely.
    Fact: This medicine is for short-term use. If cough persists beyond 7 days, consult a doctor.

🔄 Alternative Options

Generic Alternatives

  • Bromhexine + Guaifenesin syrup (various manufacturers)

Brand Alternatives

  • Asmaril Syrup (DWD Pharmaceuticals Ltd)

📊 Comparison with Similar Medicines

[{"medicine":"Bromhexine + Guaifenesin","composition":"Bromhexine 2mg/5ml + Guaifenesin 50mg/5ml","uses":"Productive cough","notes":"Combination provides mucolytic and expectorant action."},{"medicine":"Ambroxol + Guaifenesin","composition":"Ambroxol 15mg/5ml + Guaifenesin 50mg/5ml","uses":"Productive cough","notes":"Ambroxol is a metabolite of bromhexine with similar action."},{"medicine":"Bromhexine alone","composition":"Bromhexine 4mg/5ml","uses":"Productive cough","notes":"Only mucolytic, no expectorant."},{"medicine":"Guaifenesin alone","composition":"Guaifenesin 100mg/5ml","uses":"Productive cough","notes":"Only expectorant, no mucolytic."}]

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