bronkion-ace tablet - Acebrophylline (100mg) + Acetylcysteine (600mg) medicine

bronkion-ace tablet - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Onamoy Healthcare LLP ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is bronkion-ace tablet used for?

Ab-Flo-N Tablet (Acebrophylline + Acetylcysteine) is used to treat RESPIRATORY. It contains Acebrophylline (100mg) + Acetylcysteine (600mg), which Acebrophylline: bronchodilation via phosphodiesterase inhibition and adenosine a. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Acebrophylline + Acetylcysteine
  • Manufacturer: Onamoy Healthcare LLP
  • Form: Allopathy
  • Pregnancy Category: C
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? Over 80% of the antiretroviral drugs used globally to combat AIDS are supplied by Indian pharmaceutical companies.

๐Ÿ’Š bronkion-ace tablet Uses & Benefits

Chronic obstructive pulmonary disease (COPD), asthma, bronchitis, bronchiectasis

Off-label uses: Cystic fibrosis, Sinusitis

๐Ÿ“‹ Drug Information

Generic Name(s)Acebrophylline + Acetylcysteine
Brand NameAb-Flo-N Tablet
ManufacturerOnamoy Healthcare LLP
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Bronchodilator
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from moisture
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues
Protein BindingAcebrophylline: ~50%; Acetylcysteine: ~50%
MetabolismHepatic metabolism
Half-LifeAcebrophylline: 8-12 hours; Acetylcysteine: 5-6 hours
ExcretionRenal excretion
BioavailabilityAcebrophylline: ~70%; Acetylcysteine: ~10%
Onset of Action30-60 minutes
Peak Plasma Time1-3 hours
Duration of Action8-12 hours

How It Works

Acebrophylline: bronchodilation via phosphodiesterase inhibition and adenosine antagonism; Acetylcysteine: mucolysis by breaking disulfide bonds in mucus glycoproteins

Mechanism Steps

1Acebrophylline inhibits phosphodiesterase, increasing cAMP levels
2Acebrophylline blocks adenosine receptors, preventing bronchoconstriction
3Acetylcysteine reduces disulfide bonds in mucus, decreasing viscosity

๐Ÿ’ก How to Take bronkion-ace tablet

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bronkion-ace tablet

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Heartburn
  • Headache
  • Dizziness

๐Ÿšจ Serious Side Effects

  • Bronchospasm
  • Stevens-Johnson syndrome
  • Anaphylaxis

โš ๏ธ Rare Side Effects

  • Hepatitis
  • Nephritis
  • Thrombocytopenia

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Theophylline Major Increased theophylline levels and toxicity risk
Warfarin Major Increased anticoagulant effect
Cimetidine Moderate Reduced clearance of acebrophylline
Ciprofloxacin Moderate Increased acebrophylline levels
Alcohol Minor Possible additive gastrointestinal irritation
Antacids Minor Reduced absorption of acebrophylline

๐Ÿšจ Major Interactions

  • Theophylline
  • Warfarin

โšก Moderate Interactions

  • Cimetidine
  • Ciprofloxacin

โ„น๏ธ Minor Interactions

  • Alcohol
  • Antacids

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

May increase risk of gastrointestinal irritation

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to any component, peptic ulcer, severe hepatic impairment

๐Ÿ“Š Monitoring Parameters

Pulmonary function tests, liver function tests, renal function tests

๐Ÿคฑ Lactation Safety

Caution advised; not recommended unless clearly needed

๐Ÿ’Š Overdose Management

Symptomatic and supportive treatment; gastric lavage if indicated

โฐ Missed Dose

Take as soon as remembered; skip if near next dose; do not double dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

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