Bronil 2mg/100mg Tablet - Uses, Price, Side Effects
What is bronil 2mg/100mg tablet used for?
Bronil 2mg/100mg Tablet is a combination medicine used to treat asthma and chronic obstructive pulmonary disease (COPD). It contains Salbutamol, a bronchodilator that relaxes airway muscles, and Theophylline, which reduces inflammation and opens airways. Together, they improve breathing and prevent wheezing.
- Generic Name: Salbutamol + Theophylline
- Manufacturer: Glenwell Pharma
- Form: Allopathy
- Pregnancy Category: A
- Prescription Required: Yes
๐ bronil 2mg/100mg tablet Uses & Benefits
Bronchial asthma, chronic obstructive pulmonary disease (COPD), chronic bronchitis, emphysema.
Off-label uses: Not commonly used off-label; theophylline sometimes used for apnea of prematurity.
๐ Drug Information
| Generic Name(s) | Salbutamol + Theophylline |
| Brand Name | Asthelite |
| Manufacturer | Glenwell Pharma |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Bronchodilator (Beta-2 agonist + Xanthine derivative) |
| Route of Administration | Oral |
| Storage | Store at room temperature (20-25ยฐC), protect from light and moisture. |
| Shelf Life | As per manufacturer |
๐ฌ Pharmacology (PK/PD)
Pharmacokinetics
How It Works
Salbutamol: Selective beta-2 adrenergic receptor agonist causing bronchodilation; Theophylline: Inhibits phosphodiesterase, increases cAMP, and blocks adenosine receptors, leading to bronchodilation and anti-inflammatory effects.
Mechanism Steps
๐ก How to Take bronil 2mg/100mg tablet
Follow your doctor's prescription exactly.
Dosage Timeline
โ ๏ธ Side Effects of bronil 2mg/100mg tablet
โ Common Side Effects
- Nausea
- Vomiting
- Headache
- Insomnia
- Nervousness
- Tremor
- Palpitations
- Tachycardia
- Increased heart rate
๐จ Serious Side Effects
- Arrhythmias
- Seizures
- Hypokalemia
- Hyperglycemia
- Severe allergic reactions
- Respiratory arrest (overdose)
โ ๏ธ Rare Side Effects
- Hepatotoxicity
- Rhabdomyolysis
- Acute pancreatitis
- Anaphylaxis
Consult your doctor if you experience any unusual symptoms.
๐ฌ Drug Interactions
| โ ๏ธ Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | Increased bleeding risk |
| Ciprofloxacin | Moderate | Increased theophylline levels |
| Propranolol | Moderate | Reduced bronchodilator effect |
๐จ Major Interactions
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants (TCAs)
- Beta-blockers
- Other xanthine derivatives
- Cimetidine
- Ciprofloxacin
- Erythromycin
- Fluconazole
- Fluvoxamine
- Methotrexate
- Phenytoin
- Rifampin
- St. John's Wort
- Verapamil
โก Moderate Interactions
- Halothane
- Lithium
- Loop diuretics
- Quinolones
- Sympathomimetics
- Thyroid hormones
โน๏ธ Minor Interactions
- Caffeine
- Nicotine
- Oral contraceptives
- Thiabendazole
๐ฝ๏ธ Food Interactions
High-fat meals may increase absorption of theophylline; caffeine-containing foods may increase side effects.
๐ท Alcohol Interaction
Alcohol may increase theophylline clearance and reduce efficacy; also may increase risk of side effects.
๐ก๏ธ Safety & Warnings
๐ซ Contraindications
Hypersensitivity to salbutamol, theophylline, or any excipients; concurrent use with other xanthines; severe cardiac disorders (e.g., tachyarrhythmias); hyperthyroidism; seizure disorders (unless controlled); peptic ulcer; porphyria.
๐ Monitoring Parameters
Serum theophylline levels (therapeutic range 5-15 mcg/mL), heart rate, blood pressure, respiratory function, signs of toxicity (nausea, vomiting, arrhythmias, seizures).
๐คฑ Lactation Safety
Salbutamol: Excreted in breast milk, use with caution; Theophylline: Excreted in breast milk, may ca
๐ Overdose Management
Salbutamol: Beta-blocker (cardioselective) for tachycardia; Theophylline: Activated charcoal, supportive care, hemodialysis in severe cases.
โฐ Missed Dose
Take as soon as remembered; if close to next dose, skip missed dose. Do not double dose.