bronac 100mg injection - Acetylcysteine (100mg) medicine

Bronac 100mg Injection: Complete Medicine Guide

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🏭 Healers Pharmaceuticals 📦 Varies by brand 💊 Allopathy 📅 Updated: Oct 17, 2026
📋 Prescription Required 💊 Generic Available
Medically Reviewed
11 min read
Evidence: Well-established for approved indications.
Reviewed by
SaathiMed Expert Panel | Oct 17, 2026
🩺
Medically Fact-Checked & Clinically Verified by SaathiMed Clinical Review Board
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026

When to Call Your Doctor IMMEDIATELY

  • Difficulty breathing or wheezing
  • Swelling of face, lips, or throat
  • Severe rash or hives
  • Chest pain or palpitations
  • Severe dizziness or fainting
  • Yellowing of skin or eyes
  • Decreased urine output

If experiencing severe symptoms, call emergency services immediately.

What is bronac 100mg injection used for?

This medicine contains acetylcysteine, a mucolytic and antidote for paracetamol overdose. It is given by injection in a hospital setting.

  • Generic Name: Acetylcysteine
  • Manufacturer: Healers Pharmaceuticals
  • Form: Allopathy
  • Pregnancy Category: Consult doctor
  • Prescription Required: Yes

🇮🇳 bronac 100mg injection के बारे में (Hindi Summary)

उपयोग: यह दवा एसिटाइलसिस्टीन नामक तत्व से बनी है और इंजेक्शन के रूप में दी जाती है। इसका उपयोग मुख्य रूप से पैरासिटामोल की अधिक मात्रा (ओवरडोज) के इलाज में किया जाता है, जिससे लिवर को नुकसान से बचाया जा सके। इसके अलावा, यह बलगम को पतला करने और श्वसन मार्ग को साफ करने में भी मदद करती है। यह दवा अस्पताल में डॉक्टर या नर्स द्वारा इंजेक्शन के माध्यम से दी जाती है। इसे घर पर स्वयं न लगाएं।

साइड इफेक्ट्स: आम दुष्प्रभावों में मतली, उल्टी और त्वचा पर चकत्ते शामिल हैं। कुछ लोगों को नाक बहना या लार बढ़ना भी हो सकता है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, सांस लेने में कठिनाई, चेहरे या गले में सूजन, और रक्तचाप में गिरावट हो सकती है। अगर ऐसा कुछ हो, तो तुरंत डॉक्टर को बताएं।

सुरक्षा सलाह: यह दवा केवल डॉक्टर या नर्स द्वारा ही दी जानी चाहिए। इसे स्वयं न लगाएं। अगर आप गर्भवती हैं, गर्भधारण की योजना बना रही हैं, या स्तनपान करा रही हैं, तो डॉक्टर को बताएं। अपनी सभी दवाओं के बारे में डॉक्टर को जानकारी दें, खासकर नाइट्रोग्लिसरीन। अस्थमा होने पर डॉक्टर की निगरानी में ही यह दवा लें। शराब का सेवन न करें।

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 bronac 100mg injection Uses & Benefits

[{"condition":"Paracetamol overdose","description":"Used as an antidote to prevent or reduce liver damage caused by paracetamol poisoning.","evidence":"Well-established"},{"condition":"Mucolytic therapy in respiratory conditions","description":"Helps thin and loosen mucus in conditions like bronchitis, cystic fibrosis, and COPD.","evidence":"Well-established"},{"condition":"Diagnostic aid in certain procedures","description":"Sometimes used to clear mucus during bronchoscopy or other airway procedures.","evidence":"Limited"}]

Off-label uses: [{"condition":"Prevention of contrast-induced nephropathy","description":"Sometimes used off-label to protect kidneys before contrast imaging, but evidence is mixed.","evidence":"Limited"},{"condition":"Infertility treatment in women with polycystic ovary syndrome","description":"Occasionally used off-label to improve ovulation, but not standard practice.","evidence":"Limited"}]

Primary treatment for: Paracetamol overdose

Also treats: Bronchitis, Cystic fibrosis, COPD

📋 Drug Information

Generic Name(s)Acetylcysteine
Brand NameAcyline Tablet
ManufacturerHealers Pharmaceuticals
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassPAIN ANALGESICS
Action ClassAcetylcysteine -Mucolytic
Route of AdministrationIntravenous (IV) injection
StorageStore at room temperature (15-30°C). Protect from light. Do not freeze.
Shelf LifeRefer to the expiry date on the packaging.
WHO GuidelineNot established from the available information.
ICMR GuidelineNot established from the available information.

👨‍⚕️ Doctor's Practical Tips

Evidence-based practical advice from experienced clinicians

1
Administer acetylcysteine as soon as possible in paracetamol overdose, ideally within 8-10 hours.
2
Monitor for allergic reactions during infusion, especially in patients with asthma.
3
Ensure adequate hydration during treatment.
4
Adjust dose in patients with severe liver or kidney impairment.
5
Avoid concurrent use with nitroglycerin due to risk of severe hypotension.
6
Educate patients about the importance of follow-up liver function tests.

🔍 Is This Medicine Right for Your Symptom?

Educational reference. Always consult a doctor for diagnosis.

✅
Paracetamol overdose
This medicine is the antidote for paracetamol overdose.
Likely Use
✅
Thick mucus in airways
This medicine helps thin mucus.
Likely Use
❌
Fever
This medicine is not a fever reducer.
Not Primary

🔬 How This Medicine Works (Pharmacology)

Pharmacokinetics

AbsorptionAcetylcysteine is administered intravenously, so absorption is not applicable. It achieves rapid systemic availability.
DistributionIt distributes widely into body tissues, including the liver, kidneys, and lungs. It crosses the placenta and is excreted in breast milk.
Protein BindingApproximately 50% bound to plasma proteins.
MetabolismAcetylcysteine is metabolized in the liver to cysteine, which is then used for glutathione synthesis or further metabolized.
Half-LifeThe elimination half-life is approximately 2 to 6 hours, but may be prolonged in liver failure.
ExcretionIt is primarily excreted in urine as metabolites.
Bioavailability100% for intravenous administration.
Onset of ActionMucolytic effects may begin within minutes to hours after injection. For paracetamol overdose, it should be given as soon as possible, ideally within 8-10 hours.
Peak Plasma TimePeak plasma concentration is reached immediately after intravenous injection.
Duration of ActionThe duration of action varies depending on the indication and dose, typically several hours.

How It Works

Acetylcysteine works by breaking disulfide bonds in mucus, reducing its viscosity and making it easier to cough up. It also acts as a precursor to glutathione, a major antioxidant that helps detoxify harmful substances in the liver. In paracetamol overdose, it replenishes glutathione stores, allowing the liver to safely metabolize the toxic metabolite NAPQI.

Mechanism Steps

1
Mucolysis: Acetylcysteine breaks disulfide bonds in mucoproteins, reducing mucus viscosity.
2
Glutathione replenishment: It provides cysteine, a precursor for glutathione synthesis, which helps detoxify harmful metabolites.
3
Antioxidant effect: It directly neutralizes free radicals, reducing oxidative stress.

💡 How to Take bronac 100mg injection

Strength: 100 mg injection

1This medicine is given by a healthcare professional.
2Do not attempt to self-administer.
3Follow your doctor's instructions regarding appointments.
4Report any side effects immediately.

Dosage Information

Adult DosageThe dose of this medicine is determined by your doctor based on the condition being treated, your weight, and your kidney and liver function. For paracetamol overdose, a common regimen is 150 mg/kg over 1 hour, followed by 50 mg/kg over 4 hours, then 100 mg/kg over 16 hours. For mucolytic use, doses may vary. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function.
Pediatric DosagePediatric dosing is not established from available information. Consult a pediatrician.
Elderly DosageElderly patients may require dose adjustment based on renal and hepatic function. Consult your doctor.
Renal ImpairmentDose adjustment may be needed in severe renal impairment. Consult your doctor.
Hepatic ImpairmentUse with caution in severe liver disease. Dose adjustment may be necessary. Consult your doctor.
Maximum Daily DoseThe maximum daily dose is determined by the prescribing doctor based on the indication and patient factors.

Dosage Timeline

🌅 Morning ❌ ☀️ Afternoon ❌ 🌆 Evening ❌ 🌙 Night ❌

🍽️ Food Timing Guide

Alcohol
Avoid
May increase risk of liver toxicity.

⏰ What to Do If You Miss a Dose

📌 This medicine is given by a healthcare professional.
→ Missed doses are unlikely. If you miss an appointment, contact your doctor to reschedule.
💡 Do not attempt to self-administer.

⚠️ Side Effects of bronac 100mg injection

✅ Common Side Effects

Nausea (Common (5-10%))
Usually resolves on its own. Inform your doctor if persistent.
Vomiting (Common (5-10%))
Stay hydrated. Consult doctor if severe.
Rash (Uncommon (1-5%))
Report to doctor. May need antihistamine.

🚨 Serious Side Effects

Anaphylaxis (Rare (<0.1%))
Seek immediate medical attention if you experience difficulty breathing, swelling, or severe rash.
Bronchospasm (Rare (<0.1%))
Seek immediate medical help if you have wheezing or difficulty breathing.
Hypotension (Rare (<0.1%))
Report dizziness or fainting immediately.

⚠️ Rare Side Effects

Seizures
Seek emergency medical care.
Liver enzyme elevation
Monitor liver function tests as advised.

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

Drug Severity Effect
Nitroglycerin Major
Activated charcoal Major
Cough suppressants Moderate

🚨 Major Interactions

  • Nitroglycerin
  • Activated charcoal

⚡ Moderate Interactions

  • Cough suppressants
  • Antibiotics (e.g., tetracycline, penicillin)

🍷 Alcohol Interaction

Avoid alcohol while receiving this medicine, as it may increase the risk of liver damage, especially in paracetamol overdose.

🔎 Check Your Other Medicines

Educational tool. Always confirm with your doctor or pharmacist.

🛡️ Safety & Warnings

🚫 Contraindications

["Known hypersensitivity to acetylcysteine","Severe asthma without medical supervision"]

⚠️ Warnings & Precautions

["Use with caution in patients with asthma.","Monitor for allergic reactions during infusion.","Avoid in patients with active peptic ulcer.","Use with caution in elderly and those with renal impairment.","Do not use if solution is discolored or contains particles."]

🤱 Lactation Safety

Acetylcysteine is excreted in breast milk. Consult your doctor before use if breastfeeding.

💊 Overdose Management

Overdose is unlikely with intravenous acetylcysteine as it is administered by healthcare professionals. If overdose is suspected, seek immediate medical attention. Treatment is supportive and symptomatic.

⏰ Missed Dose

This medicine is given by a healthcare professional, so missed doses are unlikely. If you miss an appointment for your injection, contact your doctor to reschedule as soon as possible.

Additional Safety Advice

General Safety

This medicine must be given by a healthcare professional. Do not attempt to self-administer. Inform your doctor if you are pregnant, planning to become pregnant, or breastfeeding. Tell your doctor about all other medicines you are taking, especially nitroglycerin, as it may cause severe low blood pressure. If you have asthma, your doctor will monitor you closely during the injection. Avoid alcohol while receiving this medicine as it may increase the risk of liver problems. Keep all follow-up appointments and blood tests as advised by your doctor.

👴 Special Considerations for Elderly

💡 For Patients Above 65

Elderly patients may be more susceptible to side effects such as dizziness and hypotension. Dose adjustment may be needed based on kidney and liver function.

🤰 Pregnancy Planning (TTC)

If you are planning pregnancy, consult your doctor before receiving this medicine. It is used only if clearly needed.

🏥 Post-Surgery Considerations

This medicine may be used after surgery if there is a risk of paracetamol overdose or to help clear mucus. Follow your doctor's instructions.

🦷 Dental Procedures

Inform your dentist if you have recently received this medicine. No specific precautions are established.

💚 Lifestyle Tips for Better Results

🏃
Stay well hydrated to help thin mucus.
🥗
Avoid alcohol to reduce liver strain.
😴
Follow a healthy diet rich in antioxidants.
💧
Get plenty of rest to support recovery.
🧘
Avoid smoking to improve respiratory health.

🏋️ Exercise Considerations

Avoid strenuous exercise immediately after receiving this injection, as it may cause dizziness. Resume normal activities as advised by your doctor.

🥗 Diet Recommendations

Drink plenty of water.
Eat fruits and vegetables rich in antioxidants.
Avoid alcohol.
Limit processed foods.

💼 Impact on Daily Work & Life

This medicine is given in a hospital or clinic. You may feel dizzy or nauseous after the injection. Avoid driving or operating machinery until you feel normal.

🛑 When to Stop This Medicine

Do not stop this medicine without consulting your doctor. It is given under medical supervision, and the course will be determined by your healthcare provider.

📅 Long-Term Use Effects

Long-term effects are not well established for short-term use. Prolonged use may lead to nausea, vomiting, or allergic reactions. Monitoring of liver and kidney function may be required with extended use.

🌿 Non-Medicine Approaches

These can complement medicine but do not replace prescribed treatment.

Oral acetylcysteine

May be used for mucolytic therapy in some cases.

Evidence: Well-established
Other mucolytics

Carbocisteine or bromhexine may be alternatives for mucus clearance.

Evidence: Well-established

💉 Vaccination Considerations

💉 If You're Getting Vaccinated

No known interactions with vaccines. Consult your doctor for personalized advice.

📦 Storage Guide

✅ DO

Store at room temperature (15-30°C)

❌ DON'T

Do not freeze

✅ DO

Keep in original container

❌ DON'T

Do not transfer to unmarked containers

✅ DO

Protect from light

❌ DON'T

Do not store in bathroom cabinet

✈️ Traveling with This Medicine

This medicine is given in a hospital setting, so travel advice is not applicable. If you are prescribed acetylcysteine for home use (unlikely), carry it in its original packaging with a copy of your prescription. Store at room temperature and protect from light. Check customs regulations for injectable medicines before traveling.

💰 Cost Analysis & Savings

👥 Real Patient Stories

Educational, anonymized scenarios. Individual results may vary.

👤 A 25-year-old woman accidentally took too much paracetamol.
She was brought to the emergency room where she received this medicine intravenously. The treatment was started within 6 hours of ingestion. She recovered fully without any liver damage. She was monitored for 24 hours and discharged with advice to avoid paracetamol for a few days.
💡 Lesson: Early administration of acetylcysteine is crucial to prevent liver damage in paracetamol overdose.
👤 A 60-year-old man with chronic bronchitis received this medicine to help clear mucus.
He was given acetylcysteine injection in the hospital. His breathing improved significantly, and he was able to cough up mucus more easily. He experienced mild nausea but no serious side effects.
💡 Lesson: Acetylcysteine can effectively thin mucus and improve respiratory symptoms in chronic lung conditions.

💬 Questions Patients Often Ask

Q: How long does it take to work?

A: For paracetamol overdose, it starts working immediately to protect the liver. For mucus clearance, effects may be seen within hours.

Q: Can I drive after taking this medicine?

A: This medicine may cause dizziness. Avoid driving until you know how it affects you.

Q: Is it safe during pregnancy?

A: Consult your doctor. It is used only if clearly needed.

🤔 Common Patient Concerns

💭 These are the concerns patients most commonly raise

  • Can I take this medicine at home?
  • How long does the injection take to work?
  • What if I miss a dose?
  • Is it safe in pregnancy?
  • Does it interact with other medicines?
  • What are the serious side effects?

🔄 Substitutes for bronac 100mg injection

View All

Alternative brands with exact same active ingredient:

Medical Note: Always consult your doctor before switching medications.

🛑 Myths vs. Facts

  • Myth: Acetylcysteine is only for cough.
    Fact: It is also a life-saving antidote for paracetamol overdose.
  • Myth: You can take acetylcysteine at home.
    Fact: It must be given by a healthcare professional.

🔄 Alternative Options

Generic Alternatives

  • Acetylcysteine 100 mg injection

Brand Alternatives

  • Bronac 100mg injection

📊 Comparison with Similar Medicines

[{"medicine":"Acetylcysteine","class":"Mucolytic","route":"Intravenous","main_use":"Paracetamol overdose, mucolysis"},{"medicine":"Carbocisteine","class":"Mucolytic","route":"Oral","main_use":"Respiratory conditions"}]

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