Admox Plus 250mg/8mg Capsule: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Swelling of the face, lips, tongue, or throat, or difficulty breathing.
- Severe or bloody diarrhoea, or persistent watery diarrhoea.
- Widespread painful rash with blisters or peeling skin, often with fever.
- Yellowing of the skin or eyes, dark urine, or severe abdominal pain.
- Unusual bruising or bleeding, or a persistent sore throat with fever.
- Seizures or severe confusion, especially in patients with kidney disease.
- Decreased urine output or swelling in the legs or feet.
- Chest pain or palpitations.
If experiencing severe symptoms, call emergency services immediately.
What is bromoxy 250mg/8mg tablet used for?
This medicine is a prescription oral capsule containing amoxycillin (250 mg) and bromhexine (8 mg). It is used to treat bacterial respiratory tract infections with thick mucus. Amoxycillin kills bacteria, while bromhexine thins mucus to help clear the airways. It should be taken with food, and the full course must be completed as prescribed.
- Generic Name: Amoxycillin + Bromhexine
- Manufacturer: Medipol Pharmaceuticals India Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 bromoxy 250mg/8mg tablet के बारे में (Hindi Summary)
उपयोग: यह दवा एमोक्सिसिलिन (250 मिलीग्राम) और ब्रोमहेक्सिन (8 मिलीग्राम) का संयोजन है। यह मुख्य रूप से बैक्टीरियल श्वसन संक्रमण के इलाज के लिए दी जाती है, जिसमें गाढ़ा बलगम बनता है और खांसी आती है। एमोक्सिसिलिन बैक्टीरिया को मारता है, जबकि ब्रोमहेक्सिन बलगम को पतला करके उसे बाहर निकालने में मदद करता है। यह दवा ब्रोंकाइटिस, निमोनिया और क्रोनिक ब्रोंकाइटिस के तीव्र दौरे में उपयोगी होती है। इसे डॉक्टर के परामर्श के बिना नहीं लेना चाहिए। वायरल संक्रमण जैसे सर्दी-जुकाम में यह दवा काम नहीं करती।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में मतली, उल्टी, दस्त, पेट दर्द, भूख में कमी और मुँह में धातु जैसा स्वाद शामिल हैं। कुछ लोगों को त्वचा पर चकत्ते, खुजली या सूजन भी हो सकती है। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन एलर्जी, साँस लेने में कठिनाई, चेहरे या गले में सूजन, या खूनी दस्त जैसे लक्षण दिखने पर तुरंत डॉक्टर से मिलें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। पूरा कोर्स पूरा करें, भले ही आप बेहतर महसूस करने लगें। इसे भोजन के साथ लें ताकि पेट में जलन न हो। शराब का सेवन न करें। अन्य दवाओं के साथ लेने से पहले डॉक्टर को बताएं। अगर आपको गुर्दे या लीवर की बीमारी है, तो डॉक्टर को जरूर बताएं। त्वचा पर चकत्ते, सूजन या साँस लेने में तकलीफ हो तो दवा बंद करके तुरंत डॉक्टर से मिलें।
💊 bromoxy 250mg/8mg tablet Uses & Benefits
[{"condition":"Acute bacterial bronchitis","description":"Used to treat acute bronchitis caused by susceptible bacteria when accompanied by thick, tenacious mucus that is difficult to expectorate.","evidence":"Well-established for the antibiotic component; mucolytic component has supportive evidence."},{"condition":"Acute exacerbation of chronic bronchitis","description":"Prescribed for bacterial exacerbations of chronic bronchitis to eradicate the infection and help clear retained secretions.","evidence":"Well-established for amoxycillin; bromhexine used as adjunct for mucus clearance."},{"condition":"Community-acquired pneumonia (mild, outpatient)","description":"May be used in selected mild cases of community-acquired pneumonia when a clinician determines that amoxycillin is appropriate and mucus is thick.","evidence":"Established for amoxycillin in susceptible cases; combination evidence is limited."},{"condition":"Tracheobronchitis","description":"Used when bacterial tracheobronchitis is associated with excessive or viscous mucus production.","evidence":"Limited to supportive; based on clinical practice."},{"condition":"Bronchiectasis with secondary infection","description":"May be prescribed during infective exacerbations of bronchiectasis to treat susceptible bacteria and aid mucus drainage.","evidence":"Limited; specialist use only."}]
Off-label uses: [{"condition":"Sinusitis with thick secretions","description":"Occasionally prescribed off-label for bacterial sinusitis with thick mucus, though evidence for the bromhexine component is limited.","evidence":"Limited"},{"condition":"Otitis media with effusion","description":"Not a standard use; amoxycillin may be used for acute otitis media, but bromhexine is not established for this indication.","evidence":"Limited"}]
Primary treatment for: Bacterial respiratory tract infections with thick mucus
Also treats: Acute bronchitis, Chronic bronchitis exacerbation, Community-acquired pneumonia (mild), Tracheobronchitis, Bronchiectasis with infection
📋 Drug Information
| Generic Name(s) | Amoxycillin + Bromhexine |
| Brand Name | Amexine 500mg/8mg capsule |
| Manufacturer | Medipol Pharmaceuticals India Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | ANTI INFECTIVES |
| Action Class | ANTI INFECTIVES |
| Route of Administration | Oral |
| Storage | Store this medicine at room temperature between 15°C and 30°C (59°F and 86°F). Keep it in its original container, tightly closed, and protect it from direct sunlight, moisture, and heat. Do not store it in the bathroom or near the kitchen sink. Keep it out of the reach of children and pets. Do not use it after the expiry date printed on the pack. |
| Shelf Life | The shelf life of this medicine is typically 24 months from the date of manufacture when stored under the recommended conditions. Always check the expiry date on the packaging before use. Do not use the medicine if it is past its expiry date. |
| WHO Guideline | Not established from the available information for this specific fixed-dose combination. The World Health Organization includes amoxycillin in its Model List of Essential Medicines for the treatment of various bacterial infections, but the combination with bromhexine is not specifically addressed in WHO guidelines. |
| ICMR Guideline | Not established from the available information for this specific fixed-dose combination. The Indian Council of Medical Research has published guidelines for antimicrobial use in respiratory tract infections, but the specific combination of amoxycillin and bromhexine is not individually recommended in those guidelines. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with distinct mechanisms. Amoxycillin is a semi-synthetic aminopenicillin that binds to penicillin-binding proteins (PBPs) on the bacterial cell wall, inhibiting the final transpeptidation step of peptidoglycan synthesis. This weakens the cell wall, leading to bacterial lysis and death, particularly in actively dividing bacteria. Bromhexine is a mucolytic agent that reduces the viscosity of bronchial secretions by depolymerising mucoprotein and mucopolysaccharide fibres. It also stimulates the serous cells of the bronchial glands to produce more watery secretions, which helps thin the mucus and makes it easier to cough up. Together, the antibiotic targets the bacterial cause of the infection while the mucolytic improves clearance of secretions, potentially relieving cough and congestion more effectively than either agent alone.
Mechanism Steps
💡 How to Take bromoxy 250mg/8mg tablet
Strength: Each capsule contains amoxycillin 250 mg and bromhexine 8 mg. The capsule is intended for oral administration and is an immediate-release formulation.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is one capsule taken orally two to three times a day, depending on the severity of the infection and the prescribing doctor's judgement. The exact dose and duration must be individualized by a qualified clinician based on the indication, the patient's age, weight, renal and hepatic function, and the severity of the infection. Do not exceed the prescribed dose. Always complete the full course as directed, even if you feel better. If you have kidney or liver problems, your doctor may adjust the dose or frequency. |
| Pediatric Dosage | Pediatric dosing is not established from available information for this fixed-dose combination capsule. This medicine is generally not recommended for children under 12 years of age unless specifically prescribed by a paediatrician. A paediatrician will determine the appropriate dose based on the child's weight, age, and the specific infection. Do not give this medicine to a child without medical advice. |
| Elderly Dosage | Elderly patients (above 65 years) may require a lower dose or longer dosing interval because of age-related decline in kidney function. Renal function should be assessed before and during treatment. Elderly patients are also more prone to drug interactions and side effects, especially confusion, dizziness, and gastrointestinal upset. The dose must be individualized by a qualified clinician based on renal function and overall health status. |
| Renal Impairment | In patients with renal impairment, the dose of this medicine may need to be reduced or the dosing interval lengthened. For mild renal impairment (creatinine clearance 30-60 mL/min), the usual dose may be given but with increased caution. For moderate to severe renal impairment (creatinine clearance less than 30 mL/min), the dose should be reduced and the interval extended, as determined by a clinician. Amoxycillin can accumulate and cause neurotoxicity in severe renal failure. Bromhexine also requires caution. Regular monitoring of renal function is advised. |
| Hepatic Impairment | In patients with mild to moderate hepatic impairment, no specific dose adjustment is usually required for amoxycillin, but bromhexine undergoes extensive hepatic metabolism and should be used with caution. In severe hepatic impairment, this medicine should be used only if clearly needed and under close medical supervision. Liver function should be monitored. The dose must be individualized by a qualified clinician. |
| Maximum Daily Dose | The maximum daily dose of this medicine is not established from the available information for this specific fixed-dose combination. The maximum recommended daily dose of amoxycillin is generally 4 grams per day for adults, but this combination product contains only 250 mg of amoxycillin per capsule, so the maximum daily dose would be determined by the prescribed frequency. Do not exceed the dose prescribed by your doctor. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of bromoxy 250mg/8mg tablet
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Warfarin | Major | |
| Methotrexate | Major | |
| Allopurinol | Moderate | |
| Probenecid | Moderate | |
| Oral contraceptives | Moderate | |
| Tetracyclines | Moderate | |
| Aminoglycosides | Moderate | |
| Oral typhoid vaccine | Moderate | |
| Antacids | Minor | |
| Food | Minor |
🚨 Major Interactions
- Warfarin and other oral anticoagulants
- Methotrexate
- Allopurinol
- Probenecid
⚡ Moderate Interactions
- Oral contraceptives
- Tetracyclines and chloramphenicol
- Aminoglycosides
- Typhoid vaccine (oral)
🍷 Alcohol Interaction
Alcohol should be avoided while taking this medicine. Alcohol can increase the risk of gastrointestinal irritation, nausea, and vomiting, and may add to the risk of liver-related side effects. It can also worsen dehydration if diarrhoea is present. There is no direct interaction that reduces the effectiveness of the antibiotic, but avoiding alcohol is safer and helps recovery.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Known hypersensitivity or allergy to amoxycillin, other penicillins, or any component of this medicine.","Previous severe allergic reaction (anaphylaxis) to beta-lactam antibiotics, including cephalosporins.","Active peptic ulcer disease or a history of recurrent gastrointestinal bleeding.","Severe hepatic impairment or severe renal impairment without appropriate dose adjustment.","Use in patients with infectious mononucleosis, as it increases the risk of a maculopapular rash.","Concurrent use with live bacterial vaccines (e.g., oral typhoid vaccine) due to inactivation.","Children under 12 years of age unless specifically prescribed by a paediatrician."]
⚠️ Warnings & Precautions
["Before starting this medicine, inform your doctor about all your medical conditions, especially kidney disease, liver disease, asthma, or allergies.","Tell your doctor about all prescription, over-the-counter, and herbal medicines you are taking, as interactions can occur.","This medicine may cause dizziness; avoid driving or operating heavy machinery until you know how it affects you.","Do not use this medicine to treat viral infections such as the common cold or influenza.","Complete the full prescribed course even if symptoms improve, to prevent recurrence and antibiotic resistance.","If you develop a skin rash, stop the medicine and consult your doctor immediately.","If you experience severe or bloody diarrhoea, do not take anti-diarrhoeal medicines without medical advice.","Use with caution in elderly patients, who may have reduced renal function and are more prone to side effects.","Inform your surgeon or dentist that you are taking this medicine before any surgical or dental procedure.","Do not share this medicine with others, even if they have similar symptoms."]
🤱 Lactation Safety
Amoxycillin is excreted in breast milk in small amounts and is generally considered compatible with breastfeeding. It may occasionally cause diarrhoea or thrush in the nursing infant. Bromhexine is also excreted in breast milk, and its effects on the nursing infant are not well established. This medicine should be used during breastfeeding only if prescribed by a doctor, who will weigh the benefits and risks. Monitor the infant for diarrhoea, rash, or oral thrush and consult a paediatrician if these occur.
💊 Overdose Management
Overdose with this medicine may cause nausea, vomiting, diarrhoea, and abdominal pain. In severe cases, especially in patients with renal impairment, amoxycillin can cause crystalluria, haematuria, and seizures. There is no specific antidote. Treatment is supportive and symptomatic. If a recent large overdose has been taken, activated charcoal may be considered if the patient presents within 1 to 2 hours. Maintain adequate hydration to promote urinary excretion. Monitor renal function, electrolyte levels, and neurological status. In case of seizure, manage with appropriate anticonvulsant therapy. Contact a poison control centre or emergency department immediately if an overdose is suspected.
⏰ Missed Dose
If you miss a dose of this medicine, take it as soon as you remember, provided there is enough time before your next scheduled dose. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not take two doses at the same time to make up for a missed dose. If you are unsure what to do, contact your doctor or pharmacist for advice.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor, and do not share it with anyone else, even if they have similar symptoms. Complete the full course of treatment even if you start feeling better after a few days, because stopping early can allow the infection to return and can promote antibiotic resistance. Take this medicine with a full glass of water and preferably with food to reduce the chance of stomach upset. Do not crush, chew, or open the capsule unless your doctor or pharmacist tells you to do so. Avoid alcohol while taking this medicine, as it can worsen stomach irritation and may increase the risk of liver-related side effects. Inform your doctor about all other medicines you are taking, especially blood thinners such as warfarin, methotrexate, allopurinol, probenecid, or other antibiotics, because interactions can occur. If you have kidney disease, liver disease, or a history of allergies, tell your doctor before starting this medicine. Do not use this medicine to treat a viral infection such as a cold or flu. If you develop a rash, itching, swelling, or difficulty breathing, stop the medicine and seek emergency medical help immediately. If you experience severe or bloody diarrhoea, do not take anti-diarrhoeal medicines without consulting a doctor, as this may worsen the condition. Keep this medicine out of the reach of children and store it in its original packaging.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients are more likely to have reduced kidney function, which can lead to higher blood levels of amoxycillin and an increased risk of side effects such as confusion, dizziness, and seizures. The dose may need to be adjusted based on renal function. Elderly patients are also more prone to drug interactions and gastrointestinal side effects. Close monitoring is advised, and the medicine should be used with caution in those with underlying heart, liver, or kidney disease.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, discuss with your doctor before taking this medicine. Amoxycillin is generally considered safe during pregnancy, but bromhexine is not recommended in the first trimester. Your doctor may consider alternative treatments if you are trying to conceive or are in early pregnancy. Do not start or stop any medicine without medical advice.
🏥 Post-Surgery Considerations
If you have recently undergone surgery, inform your surgeon and anaesthesiologist that you are taking this medicine. Antibiotics can interact with certain anaesthetic agents and may affect wound healing or increase the risk of bleeding if you are also on blood thinners. Your doctor will determine whether to continue, adjust, or temporarily stop the medicine before and after surgery.
🦷 Dental Procedures
Inform your dentist that you are taking this medicine before any dental procedure. Antibiotics can interact with other medications used during dental work and may increase the risk of bleeding if you are on anticoagulants. Your dentist may recommend postponing elective dental procedures until you have completed the course, or may take extra precautions. Do not stop the medicine without consulting your doctor.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
While taking this medicine, you may feel tired or dizzy. Avoid strenuous exercise until you have recovered from the infection. Light activities such as walking may be fine if you feel up to it, but do not push yourself. If you experience shortness of breath, chest pain, or severe fatigue, stop exercising and consult your doctor. Always follow your doctor's advice regarding physical activity during recovery.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, nausea, or fatigue in some people. If you experience these effects, avoid driving or operating heavy machinery until you know how the medicine affects you. Most people can continue their normal daily activities, but it is important to take the medicine at the prescribed times and to rest adequately. If your work involves close contact with others, follow infection control practices to prevent spreading the infection.
🛑 When to Stop This Medicine
You should stop taking this medicine only after completing the full prescribed course, unless your doctor advises otherwise. If you experience a serious side effect such as a severe allergic reaction, bloody diarrhoea, or yellowing of the skin or eyes, stop the medicine immediately and seek medical attention. Do not stop the medicine early just because you feel better, as this can lead to a relapse of the infection and antibiotic resistance. If you have any concerns about stopping, consult your doctor.
📅 Long-Term Use Effects
Long-term use of this medicine is not recommended and is rarely necessary. Prolonged use of antibiotics such as amoxycillin can lead to the development of antibiotic-resistant bacteria, making future infections harder to treat. It can also disrupt the normal balance of gut bacteria, leading to diarrhoea or fungal infections such as oral thrush. Regular monitoring of kidney and liver function may be required if prolonged therapy is unavoidable. If you need treatment for more than 7 to 10 days, your doctor will reassess your condition and may consider alternative treatments.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Inhaling steam can help loosen thick mucus and relieve chest congestion naturally.
Evidence: SupportiveUsing saline nasal drops or irrigation can help clear nasal congestion and thin mucus.
Evidence: SupportiveTechniques such as postural drainage and percussion can help mobilise and clear secretions.
Evidence: Well-established for certain respiratory conditionsWarm drinks with honey can soothe the throat and provide symptomatic relief from cough.
Evidence: Supportive💉 Vaccination Considerations
💉 If You're Getting Vaccinated
This medicine may reduce the effectiveness of live bacterial vaccines, such as the oral typhoid vaccine. Complete the antibiotic course at least 3 days before receiving any live bacterial vaccine. Inactivated vaccines, such as the influenza vaccine, are not affected by this medicine. Consult your doctor for specific advice regarding vaccination timing.
📦 Storage Guide
✅ DO
Store at room temperature between 15°C and 30°C.
❌ DON'T
Do not refrigerate unless specified.
✅ DO
Keep in the original container, tightly closed.
❌ DON'T
Do not transfer to unmarked containers.
✅ DO
Keep away from direct sunlight and moisture.
❌ DON'T
Do not store in the bathroom or near the kitchen sink.
✅ DO
Keep out of the reach of children and pets.
❌ DON'T
Do not use after the expiry date.
✈️ Traveling with This Medicine
When travelling, carry this medicine in its original packaging with the prescription label clearly visible. Bring a copy of your prescription or a letter from your doctor, especially for international travel, as some countries have strict rules about antibiotics. Store the capsules in a cool, dry place away from direct sunlight and moisture. If crossing time zones, adjust your dosing schedule gradually to maintain even intervals, but consult your doctor for specific advice. Keep the medicine in your carry-on luggage rather than checked baggage to avoid loss or temperature extremes. Declare it at customs if required.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: You may start to feel some improvement in cough and mucus clearance within 24 to 72 hours. However, it is important to complete the full prescribed course, which is usually 5 to 7 days, to ensure the infection is fully treated.
A: Yes, it is recommended to take this medicine with food or immediately after a meal to reduce the risk of stomach upset and nausea.
A: If you miss a dose, take it as soon as you remember, unless it is almost time for your next dose. In that case, skip the missed dose and continue with your regular schedule. Do not double dose.
A: Amoxycillin is generally considered safe during pregnancy, but bromhexine is not recommended in the first trimester. This combination should be used during pregnancy only if prescribed by a doctor after weighing the benefits and risks.
A: It is best to avoid alcohol while taking this medicine, as it can increase stomach irritation and may worsen liver-related side effects.
A: This medicine is generally not recommended for children under 12 years of age unless specifically prescribed by a paediatrician. The dose for children is determined by a paediatrician based on weight and age.
🤔 Common Patient Concerns
🔄 Substitutes for bromoxy 250mg/8mg tablet
View AllAlternative brands with exact same active ingredient:
-
mycocin syrupAdcock Ingram Healthcare Pvt Ltd ₹24.48 68.6% CHEAPER
-
bromolin 250mg/8mg syrupCipla Ltd ₹26.16 66.5% CHEAPER
-
bromolin 250mg/8mg tablet dtCipla Ltd ₹29.36 62.4% CHEAPER
-
moxyna br 250mg/8mg capsuleHamax Pharmaceuticals ₹30.00 61.5% CHEAPER
-
moxind-br 250mg/8mg capsuleIndu Drugs Pvt Ltd ₹34.00 56.4% CHEAPER
Medical Note: Always consult your doctor before switching medications.
🛑 Myths vs. Facts
- Myth: This medicine can cure any cough and cold.
Fact: This medicine is an antibiotic and mucolytic combination. It only works against bacterial infections and does not treat viral colds or flu. - Myth: You can stop taking this medicine as soon as you feel better.
Fact: You must complete the full prescribed course to prevent the infection from returning and to avoid antibiotic resistance. - Myth: This medicine is safe to take without a prescription.
Fact: This is a prescription-only medicine. It should only be taken under the supervision of a qualified doctor. - Myth: Taking this medicine with alcohol is fine.
Fact: Alcohol should be avoided as it can worsen stomach irritation and increase the risk of liver-related side effects. - Myth: This medicine can be shared with family members who have similar symptoms.
Fact: Never share antibiotics. They are prescribed for a specific person and condition, and sharing can lead to incorrect treatment and resistance.
🔄 Alternative Options
Generic Alternatives
- Amoxycillin 250 mg + Bromhexine 8 mg capsule (various manufacturers)