actimycetin suspension - Chloramphenicol (125mg) medicine

Actimycetin Suspension - Uses, Price, Side Effects

4.6 (19 reviews)

Chloramphenicol (125mg)

🏭 Medipol Pharmaceuticals India Pvt Ltd 📦 Varies by brand 💊 Allopathy 📅 Updated: Aug 22, 2026

📋 Prescription Required 💊 Generic Available

Medically Reviewed

SaathiMed Expert Panel | Aug 22, 2026

What is actimycetin suspension used for?

Actimycetin Suspension contains Chloramphenicol 125mg, an antibiotic used to treat bacterial ear infections. It works by stopping the growth of bacteria. This medicine is for external ear use only and should be used as directed by a doctor. Common side effects include irritation or redness at the application site.

Generic Name: Chloramphenicol
Manufacturer: Medipol Pharmaceuticals India Pvt Ltd
Form: Allopathy
Pregnancy Category: A
Prescription Required: Yes

💡 Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

💊 actimycetin suspension Uses & Benefits

Treatment of bacterial conjunctivitis, keratitis, and other superficial ocular infections.

Off-label uses: Prophylaxis in ocular surgery; treatment of blepharitis.

📋 Drug Information

Generic Name(s)	Chloramphenicol
Brand Name	Andrecin Eye Drop
Manufacturer	Medipol Pharmaceuticals India Pvt Ltd
Packaging / Form	Varies by brand (Allopathy)
Therapeutic Class	OTOLOGICALS
Action Class	Chloramphenicol
Route of Administration	Topical ophthalmic (eye drops).
Storage	Store at 15-30°C (59-86°F); protect from light; keep bottle tightly closed.
Shelf Life	As per manufacturer

🔬 Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed into the aqueous humor after topical ocular administration.

DistributionDistributes into ocular tissues; systemic absorption minimal with topical use.

Protein BindingApproximately 50-60% bound to plasma proteins.

MetabolismPrimarily hepatic via glucuronidation; active metabolite not significant.

Half-Life1.5-3.5 hours (systemic); topical ocular half-life not well defined.

ExcretionRenal excretion of metabolites and unchanged drug.

BioavailabilityLow systemic bioavailability due to topical administration.

Onset of ActionRapid; within 30 minutes after topical application.

Peak Plasma TimeNot applicable for topical use; minimal systemic levels.

Duration of ActionApproximately 6-8 hours after topical application.

How It Works

Inhibits bacterial protein synthesis by binding to the 50S ribosomal subunit, preventing peptide bond formation.

Mechanism Steps

1Chloramphenicol enters bacterial cell via diffusion.

2Binds reversibly to the 50S ribosomal subunit.

3Inhibits peptidyl transferase activity.

💡 How to Take actimycetin suspension

Follow your doctor's prescription exactly.

Dosage Timeline

🌅 Morning ✅ ☀️ Afternoon ❌ 🌆 Evening ✅ 🌙 Night ❌

⚠️ Side Effects of actimycetin suspension

✅ Common Side Effects

Transient stinging or burning
Blurred vision
Eye irritation
Redness

🚨 Serious Side Effects

Bone marrow suppression (aplastic anemia)
Gray baby syndrome (systemic use in neonates)
Hypersensitivity reactions

⚠️ Rare Side Effects

Optic neuritis
Peripheral neuropathy
Superinfection with resistant organisms

Consult your doctor if you experience any unusual symptoms.

🔬 Drug Interactions

⚠️ Drug	Severity	Effect
Warfarin	Major	Increased bleeding risk
Phenytoin	Moderate	Increased phenytoin levels
Rifampin	Moderate	Reduced chloramphenicol efficacy

🚨 Major Interactions

Warfarin
Phenytoin
Phenobarbital
Rifampin

⚡ Moderate Interactions

Oral contraceptives
Cyclosporine
Tacrolimus

ℹ️ Minor Interactions

Acetaminophen
Cimetidine

🍽️ Food Interactions

No significant food interactions reported.

🍷 Alcohol Interaction

Avoid alcohol; may increase risk of hepatotoxicity.

🛡️ Safety & Warnings

Liver

Moderate

Kidney

Low

Heart

Low

Pregnancy

Category A

🚫 Contraindications

Hypersensitivity to chloramphenicol; history of bone marrow depression; systemic use in neonates and pregnancy (third trimester).

📊 Monitoring Parameters

Monitor for signs of hypersensitivity, bone marrow suppression (rare with topical use), and superinfection.

🤱 Lactation Safety

Caution; small amounts excreted in breast milk, but topical use unlikely to cause significant exposu

💊 Overdose Management

Topical overdose unlikely; if ingested, induce vomiting or gastric lavage; monitor for bone marrow suppression.

⏰ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose; do not double dose.

👨‍⚕️ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

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🔄 Substitutes for actimycetin suspension

View All

Alternative brands with exact same active ingredient (Chloramphenicol (125mg)):

Medical Note: Always consult your doctor before switching medications.

⭐ User Reviews

Verified User Jul 10, 2026

This medicine was effective for me. I followed the doctor's advice.

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Regular Customer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.