bromifax eye drop - Bromfenac (0.09% w/v) + Moxifloxacin (0.5% w/v) medicine

bromifax eye drop

4.7 (16 reviews)
๐Ÿญ Optho Life Sciences Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Aug 22, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Aug 22, 2026

What is bromifax eye drop used for?

Bromifax Eye Drop (Bromfenac + Moxifloxacin) is used to treat OPHTHAL. It contains Bromfenac (0.09% w/v) + Moxifloxacin (0.5% w/v), which Bromfenac inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesi. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Bromfenac + Moxifloxacin
  • Manufacturer: Optho Life Sciences Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India is the largest provider of generic medicines globally, supplying over 50% of global vaccine demand.

๐Ÿ’Š bromifax eye drop Uses & Benefits

Treatment of postoperative inflammation and prevention of infection following cataract surgery

Off-label uses: Treatment of allergic conjunctivitis, Prevention of cystoid macular edema

๐Ÿ“‹ Drug Information

Generic Name(s)Bromfenac + Moxifloxacin
Brand NameBromifax Eye Drop
ManufacturerOptho Life Sciences Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassOPHTHAL
Action ClassNSAID + Fluoroquinolone antibiotic
Route of AdministrationOphthalmic (topical)
StorageStore at 15-25ยฐC; protect from light; keep tightly closed
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionOcular absorption following topical administration
DistributionDistributes into ocular tissues including cornea, conjunctiva, and aqueous humor
Protein BindingBromfenac: >99% bound to plasma proteins; Moxifloxacin: approximately 50% bound
MetabolismBromfenac: Hepatic via CYP2C9; Moxifloxacin: Hepatic via glucuronidation and sulfate conjugation
Half-LifeBromfenac: 1.4-2.5 hours; Moxifloxacin: 12 hours
ExcretionBromfenac: Renal (primarily as metabolites); Moxifloxacin: Renal and fecal
BioavailabilityLow systemic bioavailability due to topical ocular administration
Onset of ActionWithin 30 minutes
Peak Plasma TimeNot well defined for topical ocular use; systemic levels are low
Duration of ActionApproximately 12 hours

How It Works

Bromfenac inhibits cyclooxygenase (COX) enzymes, reducing prostaglandin synthesis; Moxifloxacin inhibits bacterial DNA gyrase and topoisomerase IV, preventing DNA replication

Mechanism Steps

1Bromfenac inhibits COX-1 and COX-2 enzymes, reducing conversion of arachidonic acid to prostaglandins
2Decreased prostaglandins lead to reduced inflammation and pain
3Moxifloxacin enters bacterial cells and binds to DNA gyrase and topoisomerase IV

๐Ÿ’ก How to Take bromifax eye drop

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of bromifax eye drop

โœ… Common Side Effects

  • Eye irritation
  • Blurred vision
  • Eye pain
  • Conjunctival hyperemia
  • Headache

๐Ÿšจ Serious Side Effects

  • Corneal perforation
  • Corneal thinning
  • Increased intraocular pressure
  • Hypersensitivity reactions

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Stevens-Johnson syndrome
  • Hepatotoxicity
  • Renal failure

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Major Increased bleeding risk
Other NSAIDs Major Additive antiplatelet effect and increased bleeding risk
Anticoagulants Major Increased bleeding risk
Corticosteroids Major Increased risk of corneal perforation
Aspirin Moderate Increased bleeding risk
Clopidogrel Moderate Increased bleeding risk
Methotrexate Moderate Increased methotrexate toxicity
Cyclosporine Moderate Increased nephrotoxicity risk
Antacids Minor Reduced absorption of moxifloxacin if taken orally; not relevant for topical use
Sucralfate Minor Reduced absorption of moxifloxacin if taken orally
Iron supplements Minor Reduced absorption of moxifloxacin if taken orally

๐Ÿšจ Major Interactions

  • Warfarin
  • Other NSAIDs
  • Anticoagulants
  • Corticosteroids

โšก Moderate Interactions

  • Aspirin
  • Clopidogrel
  • Methotrexate
  • Cyclosporine

โ„น๏ธ Minor Interactions

  • Antacids
  • Sucralfate
  • Iron supplements

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Avoid alcohol as it may increase risk of gastrointestinal bleeding with systemic NSAIDs, but topical use has minimal systemic absorption

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to bromfenac, moxifloxacin, or any component; history of asthma, urticaria, or allergic-type reactions after taking aspirin or other NSAIDs; viral infections of the cornea (e.g., herpes simplex)

๐Ÿ“Š Monitoring Parameters

Monitor for signs of infection, corneal healing, intraocular pressure, and visual acuity

๐Ÿคฑ Lactation Safety

Caution; not recommended unless clearly needed

๐Ÿ’Š Overdose Management

Not expected with topical use; if accidentally ingested, treat symptomatically

โฐ Missed Dose

Apply as soon as remembered; if near next dose, skip missed dose and resume regular schedule

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Last reviewed on: Aug 22, 2026

๐Ÿ”— View Profile

โญ User Reviews

Trusted Reviewer Jul 10, 2026

Found this to be a helpful product. Good results.

Certified Buyer Jul 10, 2026

Helpful and effective medicine as per my experience. Always consult a doctor.

Verified User Jul 10, 2026

Good quality medicine. Satisfied with the outcome.

Verified User Jul 10, 2026

Found this to be a helpful product. Good results.

Verified User Jul 10, 2026

Effective and reliable. Worked as expected.

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