brom syrup - Bromocriptine (NA) medicine

brom syrup - Uses, Price, Side Effects & Substitutes

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๐Ÿญ Hi Tech Pharmaceuticals Pvt Ltd ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 28, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 28, 2026

What is brom syrup used for?

Brom 2.5mg Tablet (Bromocriptine) is used to treat NEURO CNS. It contains Bromocriptine (NA), which Ergot alkaloid dopamine D2 receptor agonist; inhibits prolactin secretion.. Always consult your doctor before use. Take as prescribed.

  • Generic Name: Bromocriptine
  • Manufacturer: Hi Tech Pharmaceuticals Pvt Ltd
  • Form: Allopathy
  • Pregnancy Category: B
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š brom syrup Uses & Benefits

Hyperprolactinemia; Parkinson's disease; acromegaly; type 2 diabetes (off-label).

Off-label uses: Type 2 diabetes; cocaine dependence; neuroleptic malignant syndrome.

๐Ÿ“‹ Drug Information

Generic Name(s)Bromocriptine
Brand NameBrom 2.5mg Tablet
ManufacturerHi Tech Pharmaceuticals Pvt Ltd
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassNEURO CNS
Action ClassDopamine agonists-Hyperprolactinemia
Route of AdministrationOral.
StorageStore at 20-25ยฐC (68-77ยฐF); protect from light and moisture.
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionRapidly absorbed from gastrointestinal tract; peak plasma concentration within 1-2 hours.
DistributionDistributes widely; crosses blood-brain barrier; enters breast milk.
Protein Binding90-96% bound to serum albumin.
MetabolismExtensively metabolized in the liver via CYP3A4.
Half-LifeBiphasic: initial half-life 6-8 hours, terminal half-life 50 hours.
ExcretionPrimarily excreted in feces (85%) via bile; renal excretion accounts for 2-6%.
BioavailabilityApproximately 28% due to first-pass metabolism.
Onset of Action30-60 minutes.
Peak Plasma Time1-2 hours.
Duration of Action4-8 hours.

How It Works

Ergot alkaloid dopamine D2 receptor agonist; inhibits prolactin secretion.

Mechanism Steps

1Bromocriptine binds to dopamine D2 receptors on lactotroph cells in the anterior pituitary.
2Activation of D2 receptors inhibits adenylyl cyclase, reducing cAMP levels.
3Decreased cAMP leads to reduced prolactin gene transcription and secretion.

๐Ÿ’ก How to Take brom syrup

Follow your doctor's prescription exactly.

โš ๏ธ Side Effects of brom syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Headache
  • Dizziness
  • Fatigue
  • Constipation
  • Nasal congestion

๐Ÿšจ Serious Side Effects

  • Hypotension
  • Hallucinations
  • Confusion
  • Pleural effusion
  • Retroperitoneal fibrosis
  • Cardiac valvulopathy

โš ๏ธ Rare Side Effects

  • Stroke
  • Myocardial infarction
  • Psychosis
  • Hepatic dysfunction

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Erythromycin Major Increased bromocriptine levels and toxicity risk.
Clarithromycin Major Increased bromocriptine levels and toxicity risk.
Ketoconazole Major Increased bromocriptine levels and toxicity risk.
Itraconazole Major Increased bromocriptine levels and toxicity risk.
Ritonavir Major Increased bromocriptine levels and toxicity risk.
Nefazodone Major Increased bromocriptine levels and toxicity risk.
Antipsychotics Moderate Antagonism of dopamine effects; reduced efficacy.
Metoclopramide Moderate Antagonism of dopamine effects; reduced efficacy.
MAOIs Moderate Increased risk of hypertensive crisis.
Methyldopa Moderate Reduced antihypertensive effect.
Reserpine Moderate Reduced antiparkinsonian effect.
Alcohol Minor Increased CNS depression and hypotension.
Caffeine Minor Possible reduced efficacy.
Oral contraceptives Minor Possible reduced efficacy.

๐Ÿšจ Major Interactions

  • Erythromycin
  • Clarithromycin
  • Ketoconazole
  • Itraconazole
  • Ritonavir
  • Nefazodone

โšก Moderate Interactions

  • Antipsychotics
  • Metoclopramide
  • MAOIs
  • Methyldopa
  • Reserpine

โ„น๏ธ Minor Interactions

  • Alcohol
  • Caffeine
  • Oral contraceptives

๐Ÿฝ๏ธ Food Interactions

High-fat meals may increase absorption; avoid alcohol.

๐Ÿท Alcohol Interaction

May increase risk of hypotension and CNS depression.

๐Ÿ›ก๏ธ Safety & Warnings

๐Ÿšซ Contraindications

Hypersensitivity to ergot alkaloids; uncontrolled hypertension; preeclampsia; postpartum eclampsia; nursing mothers.

๐Ÿ“Š Monitoring Parameters

Blood pressure; prolactin levels; liver function tests; cardiac monitoring in high doses.

๐Ÿคฑ Lactation Safety

Contraindicated; suppresses lactation and may cause adverse effects in infant.

๐Ÿ’Š Overdose Management

Gastric lavage; activated charcoal; supportive care; may require dopamine antagonists.

โฐ Missed Dose

Take as soon as remembered unless near next dose; do not double dose.

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 28, 2026

๐Ÿ”— View Profile

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