Broful Syrup: Complete Medicine Guide
Clinical Reference Standards: CDSCO (Central Drugs Standard Control Organisation), Indian Pharmacopoeia (IP) & WHO | Last Updated: September 2026
When to Call Your Doctor IMMEDIATELY
- Difficulty breathing or worsening of breathing after taking the medicine
- Chest pain or palpitations
- Severe dizziness or fainting
- Swelling of face, lips, or throat
- Severe rash or blistering of skin
- Irregular heartbeat
- Muscle weakness or cramps
If experiencing severe symptoms, call emergency services immediately.
What is broful syrup used for?
This medicine is a combination of terbutaline (a bronchodilator) and bromhexine (a mucolytic) used to relieve bronchospasm and loosen mucus in conditions like bronchitis and asthma. It is available as an oral syrup and should be taken as prescribed by a doctor.
- Generic Name: Terbutaline + Bromhexine
- Manufacturer: Fulfil Healthcare Pvt Ltd
- Form: Allopathy
- Pregnancy Category: Consult doctor
- Prescription Required: Yes
🇮🇳 broful syrup के बारे में (Hindi Summary)
उपयोग: यह दवा टर्ब्यूटलीन और ब्रोमहेक्सिन का संयोजन है, जिसका उपयोग ब्रोंकाइटिस और अस्थमा जैसी श्वसन संबंधी समस्याओं में सांस लेने में आसानी और बलगम को पतला करने के लिए किया जाता है। यह सिरप के रूप में उपलब्ध है और डॉक्टर के निर्देशानुसार लेनी चाहिए।
साइड इफेक्ट्स: इस दवा के सामान्य दुष्प्रभावों में हाथ-पैर कांपना, घबराहट, सिरदर्द, चक्कर आना, जी मिचलाना, उल्टी, पेट में असहजता और दिल की धड़कन तेज होना शामिल हो सकते हैं। गंभीर दुष्प्रभाव दुर्लभ हैं, लेकिन यदि सांस लेने में कठिनाई, चेहरे या गले में सूजन, तेज धड़कन या सीने में दर्द हो तो तुरंत डॉक्टर से संपर्क करें।
सुरक्षा सलाह: इस दवा को डॉक्टर के बताए अनुसार ही लें। खुराक बढ़ाएं या घटाएं नहीं। उपयोग से पहले बोतल को अच्छी तरह हिलाएं। सही मापने वाले कप या चम्मच का उपयोग करें। यदि आपको चक्कर या कंपन महसूस हो तो वाहन चलाने या मशीन चलाने से बचें। यदि आप गर्भवती हैं, स्तनपान करा रही हैं, या आपको हृदय, गुर्दे, यकृत, मधुमेह या थायरॉइड की समस्या है तो डॉक्टर को बताएं। बच्चों की पहुंच से दूर रखें।
💊 broful syrup Uses & Benefits
[{"condition":"Acute bronchitis","description":"Helps relieve bronchospasm and loosen thick mucus, making breathing easier and cough more productive.","evidence":"Well-established"},{"condition":"Chronic bronchitis","description":"Used to manage symptoms of chronic bronchitis by reducing bronchospasm and thinning mucus.","evidence":"Well-established"},{"condition":"Asthma","description":"Provides symptomatic relief of bronchospasm in asthma, but is not a substitute for inhaled corticosteroids or long-term controller medications.","evidence":"Established"},{"condition":"Productive cough with thick mucus","description":"Bromhexine helps break down mucus, making it easier to cough out, while terbutaline opens airways.","evidence":"Established"}]
Off-label uses: [{"condition":"Not established from the available information.","description":"Not established from the available information.","evidence":"Not established from the available information."}]
Primary treatment for: Bronchospasm associated with bronchitis or asthma
Also treats: Chronic obstructive pulmonary disease (COPD), Productive cough, Respiratory tract infections with thick mucus
📋 Drug Information
| Generic Name(s) | Terbutaline + Bromhexine |
| Brand Name | Askafex TR Suspension |
| Manufacturer | Fulfil Healthcare Pvt Ltd |
| Packaging / Form | Varies by brand (Allopathy) |
| Therapeutic Class | RESPIRATORY |
| Action Class | Bronchodilator + Mucolytic |
| Route of Administration | Oral |
| Storage | Store at room temperature (15-30°C) in a cool, dry place. Protect from direct sunlight and moisture. Do not freeze. Keep the bottle tightly closed when not in use. |
| Shelf Life | 24 months from the date of manufacture, or as indicated on the packaging. |
| WHO Guideline | Not established from the available information. |
| ICMR Guideline | Not established from the available information. |
👨⚕️ Doctor's Practical Tips
Evidence-based practical advice from experienced clinicians
🔍 Is This Medicine Right for Your Symptom?
Educational reference. Always consult a doctor for diagnosis.
🔬 How This Medicine Works (Pharmacology)
Pharmacokinetics
How It Works
This medicine combines two active ingredients with complementary actions. Terbutaline is a selective beta-2 adrenergic receptor agonist that binds to beta-2 receptors on the smooth muscle cells of the airways, leading to relaxation of bronchial smooth muscle and widening of the airways (bronchodilation). Bromhexine is a mucolytic agent that works by breaking down the structure of mucus, reducing its viscosity and making it easier to expel. Together, they help relieve bronchospasm and clear mucus from the respiratory tract.
Mechanism Steps
💡 How to Take broful syrup
Strength: Each 5 mL of syrup contains Terbutaline 100 mg and Bromhexine 2.5 mg.
Dosage Information
| Adult Dosage | The usual adult dose of this medicine is 5 to 10 mL (one to two teaspoons) taken two to three times a day, or as prescribed by your doctor. The dose may vary depending on the condition being treated and the patient's response. Do not exceed the recommended dose. Dose must be individualized by a qualified clinician based on indication, age, weight, renal and hepatic function. |
| Pediatric Dosage | Pediatric dosing is not established from available information. Consult a pediatrician. |
| Elderly Dosage | Elderly patients may be more sensitive to the effects of terbutaline, especially cardiovascular effects. Use with caution and start with a lower dose as prescribed by a doctor. Dose must be individualized by a qualified clinician based on renal and hepatic function. |
| Renal Impairment | Use with caution in patients with renal impairment. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Hepatic Impairment | Use with caution in patients with hepatic impairment. Dose adjustment may be necessary. Consult your doctor for individualized dosing. |
| Maximum Daily Dose | The maximum daily dose should not exceed 30 mL (6 teaspoons) in adults, or as prescribed by a doctor. Do not exceed the recommended dose. |
Dosage Timeline
🍽️ Food Timing Guide
⏰ What to Do If You Miss a Dose
⚠️ Side Effects of broful syrup
✅ Common Side Effects
🚨 Serious Side Effects
⚠️ Rare Side Effects
Consult your doctor if you experience any unusual symptoms.
🔬 Drug Interactions
| Drug | Severity | Effect |
|---|---|---|
| Propranolol | Major | |
| MAOIs | Major | |
| Tricyclic antidepressants | Major | |
| Pseudoephedrine | Major | |
| Furosemide | Moderate | |
| Corticosteroids | Moderate | |
| Theophylline | Moderate | |
| Digoxin | Moderate | |
| Antacids | Minor | |
| Cough suppressants | Minor |
🚨 Major Interactions
- Non-selective beta-blockers (e.g., propranolol)
- Monoamine oxidase inhibitors (MAOIs)
- Tricyclic antidepressants
- Other sympathomimetic agents (e.g., pseudoephedrine)
⚡ Moderate Interactions
- Diuretics (e.g., furosemide)
- Corticosteroids
- Xanthine derivatives (e.g., theophylline)
- Digoxin
🍷 Alcohol Interaction
Avoid consuming alcohol while taking this medicine. Alcohol may increase the risk of dizziness, drowsiness, and cardiovascular side effects such as rapid heartbeat. It may also worsen stomach irritation.
🔎 Check Your Other Medicines
Educational tool. Always confirm with your doctor or pharmacist.
🛡️ Safety & Warnings
🚫 Contraindications
["Hypersensitivity to terbutaline, bromhexine, or any component of the formulation","Severe cardiac disease, especially arrhythmias or severe coronary insufficiency","Uncontrolled hypertension","Severe hyperthyroidism","Use with non-selective beta-blockers"]
⚠️ Warnings & Precautions
["Use with caution in patients with cardiovascular disorders, including coronary insufficiency, arrhythmias, and hypertension.","Use with caution in patients with diabetes mellitus, as terbutaline may increase blood glucose levels.","Use with caution in patients with hyperthyroidism, as terbutaline may exacerbate symptoms.","Use with caution in patients with seizure disorders.","Use with caution in patients with renal or hepatic impairment.","Do not exceed the recommended dose.","If symptoms persist or worsen, consult your doctor.","Keep out of reach of children."]
🤱 Lactation Safety
It is not known whether terbutaline and bromhexine are excreted in human breast milk. Consult your doctor before using this medicine while breastfeeding.
💊 Overdose Management
Overdose may cause severe tachycardia, palpitations, tremor, nausea, vomiting, and hypotension. In case of overdose, seek immediate medical attention. Treatment is supportive and symptomatic. Monitor cardiac function and electrolyte levels. There is no specific antidote for terbutaline or bromhexine.
⏰ Missed Dose
If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose to catch up.
Additional Safety Advice
Take this medicine exactly as prescribed by your doctor. Do not increase or decrease the dose without consulting your doctor. Shake the bottle well before each use. Use a proper measuring cup or spoon to measure the dose accurately. Avoid driving or operating heavy machinery if you feel dizzy or shaky after taking this medicine. Inform your doctor if you have heart disease, high blood pressure, diabetes, thyroid problems, or kidney or liver disease. Do not take this medicine with other cough and cold medicines without consulting your doctor. If you are pregnant, planning to become pregnant, or breastfeeding, tell your doctor before taking this medicine. Keep this medicine out of reach of children. Store it in a cool, dry place away from direct sunlight. Do not use this medicine after the expiry date.
👴 Special Considerations for Elderly
💡 For Patients Above 65
Elderly patients may be more sensitive to the cardiovascular effects of terbutaline, such as increased heart rate and palpitations. Use with caution and lower doses may be required. Monitor renal and hepatic function.
🤰 Pregnancy Planning (TTC)
If you are planning to become pregnant, consult your doctor before taking this medicine. The safety of this combination during pregnancy has not been fully established. Your doctor will weigh the benefits and risks.
🏥 Post-Surgery Considerations
Inform your surgeon and anesthesiologist if you are taking this medicine before surgery. Terbutaline may interact with certain anesthetic agents and can affect heart rate and blood pressure during surgery.
🦷 Dental Procedures
Inform your dentist if you are taking this medicine. It may cause dry mouth or interact with certain medications used in dental procedures. No specific precautions are generally required, but your dentist should be aware of your medication.
💚 Lifestyle Tips for Better Results
🏋️ Exercise Considerations
Avoid strenuous exercise if you have breathing difficulties. Consult your doctor before starting any exercise program. If you experience dizziness, palpitations, or shortness of breath during exercise, stop and seek medical advice.
🥗 Diet Recommendations
💼 Impact on Daily Work & Life
This medicine may cause dizziness, tremor, or nervousness, which can affect your ability to drive or operate machinery. Avoid these activities until you know how the medicine affects you. It is advisable to inform your employer if your work involves operating heavy machinery.
🛑 When to Stop This Medicine
Do not stop taking this medicine without consulting your doctor. If you experience severe side effects or your symptoms worsen, contact your doctor immediately. The duration of treatment will be determined by your doctor based on your condition.
📅 Long-Term Use Effects
Long-term use of this medicine should be under medical supervision. Prolonged use of terbutaline may lead to tolerance, reduced effectiveness, and potential cardiac effects. Regular monitoring of heart rate, blood pressure, and potassium levels may be required. Bromhexine is generally well tolerated for short-term use. Do not use for longer than prescribed without consulting your doctor.
🌿 Non-Medicine Approaches
These can complement medicine but do not replace prescribed treatment.
Helps loosen mucus and ease breathing.
Evidence: Traditional remedy with some supportive evidence.Techniques to help clear mucus from the airways.
Evidence: Well-established for certain respiratory conditions.May be prescribed instead of oral terbutaline for targeted relief.
Evidence: Well-established.💉 Vaccination Considerations
💉 If You're Getting Vaccinated
There are no known interactions between this medicine and vaccines. However, if you are scheduled for vaccination, inform your healthcare provider about all medicines you are taking.
📦 Storage Guide
✅ DO
Store at room temperature (15-30°C)
❌ DON'T
Do not refrigerate unless specified
✅ DO
Keep in original container
❌ DON'T
Do not transfer to unmarked containers
✅ DO
Keep away from direct sunlight
❌ DON'T
Do not store in bathroom cabinet
✅ DO
Keep out of reach of children
❌ DON'T
Do not use after expiry date
✈️ Traveling with This Medicine
When traveling, carry this medicine in its original packaging with the prescription label intact. Bring a copy of your prescription or doctor's note, especially for international travel. Store it in a cool, dry place away from direct sunlight. If traveling across time zones, adjust dosing times gradually as advised by your doctor. Check customs regulations for carrying prescription medicines.
💰 Cost Analysis & Savings
👥 Real Patient Stories
Educational, anonymized scenarios. Individual results may vary.
💬 Questions Patients Often Ask
A: The bronchodilator effect usually starts within 30 to 60 minutes after taking the syrup. The mucolytic effect may take longer to become noticeable.
A: Yes, you can take it with or without food. If it upsets your stomach, take it with a meal or snack.
A: If you miss a dose, take it as soon as you remember. If it is almost time for your next dose, skip the missed dose and continue with your regular schedule. Do not double the dose.
A: Pediatric dosing is not established from available information. Consult a pediatrician for appropriate dosing.
A: Consult your doctor before taking this medicine if you are pregnant or planning to become pregnant. The benefits and risks will be evaluated.
🤔 Common Patient Concerns
🛑 Myths vs. Facts
- Myth: This medicine can cure asthma permanently.
Fact: This medicine provides symptomatic relief but does not cure asthma. Asthma management requires long-term controller medications and lifestyle measures. - Myth: More syrup means faster relief.
Fact: Taking more than the prescribed dose can cause serious side effects. Always follow your doctor's instructions. - Myth: It is safe to take this medicine without a prescription.
Fact: This is a prescription medicine. Self-medication can be harmful. Always consult a doctor before use.
🔄 Alternative Options
Generic Alternatives
- Terbutaline + Bromhexine syrup
Brand Alternatives
- Broful Syrup