brofex syrup - Ambroxol (15mg) + Guaifenesin (50mg) medicine

Brofex Syrup - Uses, Price, Side Effects

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๐Ÿญ Biosys Medisciences ๐Ÿ“ฆ Varies by brand ๐Ÿ’Š Allopathy ๐Ÿ“… Updated: Jun 29, 2026
๐Ÿ“‹ Prescription Required ๐Ÿ’Š Generic Available
Medically Reviewed
SaathiMed Expert Panel | Jun 29, 2026

What is brofex syrup used for?

Brofex Syrup contains Ambroxol (15mg) and Guaifenesin (50mg). It is used for cough with phlegm (productive cough). Ambroxol is a mucolytic that breaks down mucus, while Guaifenesin is an expectorant that helps clear mucus from the airways. Together, they relieve chest congestion and make coughing more productive.

  • Generic Name: Ambroxol + Guaifenesin
  • Manufacturer: Biosys Medisciences
  • Form: Allopathy
  • Pregnancy Category: A
  • Prescription Required: Yes
๐Ÿ’ก Did You Know? India has the highest number of USFDA-compliant plants outside the USA.

๐Ÿ’Š brofex syrup Uses & Benefits

Productive cough, acute/chronic bronchitis, COPD, bronchiectasis

Off-label uses: None well-established

๐Ÿ“‹ Drug Information

Generic Name(s)Ambroxol + Guaifenesin
Brand NameAmbrolite-S Expectorant
ManufacturerBiosys Medisciences
Packaging / FormVaries by brand (Allopathy)
Therapeutic ClassRESPIRATORY
Action ClassMucolytic and Expectorant
Route of AdministrationOral
StorageStore at room temperature (20-25ยฐC), protect from light
Shelf LifeAs per manufacturer

๐Ÿ”ฌ Pharmacology (PK/PD)

Pharmacokinetics

AbsorptionWell absorbed orally
DistributionDistributes widely in body tissues
Protein BindingAmbroxol: ~90%; Guaifenesin: ~50%
MetabolismAmbroxol: Hepatic; Guaifenesin: Hepatic
Half-LifeAmbroxol: 7-12 hours; Guaifenesin: 1 hour
ExcretionAmbroxol: Renal; Guaifenesin: Renal
BioavailabilityAmbroxol: ~70%; Guaifenesin: ~95%
Onset of Action30-60 minutes
Peak Plasma TimeAmbroxol: 1-3 hours; Guaifenesin: 0.5-1 hour
Duration of Action6-12 hours

How It Works

Ambroxol increases secretion of respiratory tract fluid and reduces mucus viscosity; Guaifenesin increases respiratory tract fluid to thin bronchial secretions.

Mechanism Steps

1Ambroxol stimulates serous cells in bronchial glands to increase thin secretions
2Ambroxol depolymerizes mucopolysaccharides, reducing mucus viscosity
3Guaifenesin increases respiratory tract fluid volume, thinning mucus

๐Ÿ’ก How to Take brofex syrup

Follow your doctor's prescription exactly.

Dosage Timeline

๐ŸŒ… Morning โœ… โ˜€๏ธ Afternoon โŒ ๐ŸŒ† Evening โœ… ๐ŸŒ™ Night โŒ

โš ๏ธ Side Effects of brofex syrup

โœ… Common Side Effects

  • Nausea
  • Vomiting
  • Diarrhea
  • Dizziness
  • Headache

๐Ÿšจ Serious Side Effects

  • Severe allergic reaction
  • Stevens-Johnson syndrome
  • Bronchospasm

โš ๏ธ Rare Side Effects

  • Anaphylaxis
  • Angioedema
  • Renal calculi

Consult your doctor if you experience any unusual symptoms.

๐Ÿ”ฌ Drug Interactions

โš ๏ธ DrugSeverityEffect
Warfarin Moderate Increased risk of bleeding
Cough suppressants Moderate Reduced effectiveness of expectorant
Anticholinergics Minor May reduce bronchial secretions

๐Ÿšจ Major Interactions

  • Cough suppressants (e.g., codeine)
  • Anticholinergics

โšก Moderate Interactions

  • MAOIs
  • Antihypertensives

โ„น๏ธ Minor Interactions

  • Antacids
  • Cimetidine

๐Ÿฝ๏ธ Food Interactions

No significant food interactions

๐Ÿท Alcohol Interaction

Avoid alcohol; may increase sedation

๐Ÿ›ก๏ธ Safety & Warnings

Liver
Low
Kidney
Low
Heart
Low
Pregnancy
Category A

๐Ÿšซ Contraindications

Hypersensitivity to any component, peptic ulcer, severe hepatic/renal impairment

๐Ÿ“Š Monitoring Parameters

Cough frequency, sputum characteristics, respiratory function

๐Ÿคฑ Lactation Safety

Use with caution; not recommended

๐Ÿ’Š Overdose Management

Gastric lavage, supportive care, monitor for CNS depression

โฐ Missed Dose

Take as soon as remembered; skip if near next dose

๐Ÿ‘จโ€โš•๏ธ Reviewed by Expert

SaathiMed Expert Panel

MD, PhD - Pharmacology

Reviewed: Jun 29, 2026

๐Ÿ”— View Profile

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